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Heart Chapter 13 Pages 252 – 273 Page 253 Functions of the Circulatory System  The heart is the pump that circulates blood to all parts of the body  Arteries, veins, & capillaries transport the blood  Blood carries oxygen & nutrients to the cells & carries waste products away  Lymph system returns excess fluid from the tissues the circulation Page ? Major Blood Circuits  Blood leaves the heart through arteries & returns by veins  Blood circulation routes • General or systemic circulation • Pulmonary circulation Pages 253 – 254  The The Heart circulatory system is efficient because of the heart – a tough, simply constructed muscle about the size of a closed fist; weighs about a pound  Location: thoracic cavity (between the lungs); apex of the heart points to the left  Stethoscope allows you to hear the heartbeat  If blood flow stops: • 5 seconds or more = loss of consciousness • 15 to 20 seconds = muscles twitch convulsively • 4 to 5 minutes = brain cells are damaged Page 253 Figure 13-1 Page 254 Structure of the Heart Heart = Hollow, muscular, double pump  Surrounding the heart is the Pericardium (a double layer of fibrous tissue which is filled with pericardial fluid)  Epicardium (visceral or serous pericardium)= the thin inner covering of the heart. [the outer layer of the pericardium is the parietal or fibrous pericardium]  Myocardium = Cardiac muscle tissue  Endocardium = inner lining of the heart; covers the heart valves & lines the blood vessels, providing a smooth transit for the flowing blood.  Page 256 Structure of the Heart  Interventricular septum = completely separates the blood in the right half & left half of the heart.  Leading to the heart • Superior & inferior vena cava • Coronary sinus • Pulmonary veins  Leading away from the heart • Pulmonary artery • Aorta Page 254 Figure 13-2 Page 255 Figure 13-3 Page 256 Chambers & Valves  Septum separates the heart into right and left halves; then each of these halves are separated into an upper & lower chambers • • Upper chambers – Left & right atria (singular atrium) Lower chambers – Left & right ventricles  Heart has four valves which keeps blood flowing in one direction Page 256   Valves Atrioventricular valves • Tricuspid valve (separates the right atria and right ventricle) • Bicuspid or mitral valve (separates the left atria and left ventricle) Semilunar valves • Pulmonary semilunar valve (opening of the pulmonary arteries) • Aortic semilunar valve (opening of the aorta) Page 257 Physiology of the Heart  Double pump • Right side of the heart – Deoxygenated blood • Left side of the heart – Oxygenated blood Page 257 Heart Rate & Cardiac Output  Normal adult rate is between 72-80 beats per minute  With each beat 60-80 mL of blood are ejected from the ventricles = Stroke volume  Cardiac output = stroke volume x heart rate  Exercise increases cardiac output Page 258 Heart Sounds  lubb dupp sounds = sounds the valves make when they close • Lubb  • Tricuspid and bicuspid valves (S1) Dupp  Aortic and pulmonary valves (S2) Pages 258 – 259 Conduction System  Electrical impulses cause rhythmic beating of the heart • Sinoatrial (SA) node [pacemaker] – sends out an electrical impulse that begins/regulates the heartbeat. This impulse causes the atria to contract. It then sends its impulse to the AV node. • Atrioventricular (AV) node – catches the impulse & sends it on to the atrioventricular bundle (bundle of His) • Bundle of His – passes the impulse on to the Purkinje fibers • Purkinje fibers –causes the ventricles to contract Page 258 Figure 13-7 Page 259 ECG or EKG  The electrocardiogram is a device to record the electrical activity of the heart • Systole – Contraction • Diastole – Relaxation  Positive & negative deflection  P wave – atrial depolarization  QRS – ventricular depolarization  T waves – ventricular repolarization Page 259 Page 259 SB Effects of Aging  Heart muscle fibers replaced by fibrous tissue  Heart valves increase in thickness  Cardiac output decreases  Changes become more significant when elderly person becomes physically or mentally stressed Pages 259 – 260 Prevention of Heart Disease Heart disease is the leading cause of death for both men & women in the US (Coronary heart disease) • Risk factors – family history, high blood pressure, high cholesterol, diabetes, current smoking, physical inactivity, & obesity.  Steps to lower risk or prevent heart disease • Lower blood cholesterol levels & triglycerides • Control & prevent high blood pressure • Lose weight & have regular exercise & a healthy diet • No tobacco use • Alcohol – Men: 2 drinks & Women: 1 drink  Pages 260 – 261 Diagnostic Tests – Noninvasive  Angiography  Cardiac MRI  Coronary calcium scoring/heart scan  Echocardiography  Electrocardiogram  Exercise stress tests  Holter monitor  MUGA (multiple gated acquisition scan)  Nuclear perfusion Page 261 Diagnostic Tests – Invasive  Cardiac catheterization  IVUS (intravascular coronary ultrasound)  TEE Page 261 Diagnostic Tests – Blood Tests  Arterial blood gases  BNP  Lipid panel  C-reactive protein  Cardiac Troponin T Page 262 Diseases of the Heart – Common Symptoms Arrhythmia – any change or deviation from the normal rate or rhythm of the heart  Bradycardia – slow heart rate (fewer than 60 beats per minute)  Tachycardia – rapid heart rate (more than 100 beats pre minute  Murmurs – indicate defects in the valves of the heart.  Mitral valve prolapse – the valve between the left atrium & left ventricle closes imperfectly.  Page 262 Diseases of the Coronary Artery  Coronary artery disease (CAD) = a narrowing of the coronary arteries that supply blood to the heart muscle. If these arteries get blocked completely a myocardial infarction may occur.  Angina pectoris (angina) = severe chest pain that arises when the heart does not receive enough oxygen.  Myocardial infarction (MI or heart attack) = death of heart muscle caused by a lack of blood supply to the myocardium. Pages 262 – 264 Infectious Diseases of the Heart  Pericarditis = inflammation of the outer membrane covering the heart.  Myocarditis = inflammation of the heart muscle  Endocarditis = inflammation of the membrane that lines the heart & covers the valves. May lead to a blood clot.  Rheumatic heart disease = results from frequent strep throat infections that then travel to the heart. May lead to the mitral valve leaking. Page 264 Heart Failure  When the ventricles of the heart are unable to contract effectively & blood pools in the heart  Symptoms depend on which ventricle fails • Left ventricle failure  Dyspnea (shortness of breath) • Right ventricle failure  Engorgement of organs, edema (excessive fluid in tissues) of the legs & feet, & ascites (abnormal accumulation of serous fluid in the abdominal cavity) Page 264 Congestive Heart Failure  Similar to heart failure  Left-sided failure – pulmonary edema  Right-sided failure – fluid buildup throughout body  Treatment • Cardiotonics, diuretics, vasodilators, & betablockers Pages 264 – 265 Rhythm/Conduction Defects  Heart block – interruption of the AV node message from the SA node • First-degree block – momentary delay at the AV node before the impulse is transmitted to the ventricles. • Second-degree block – 2 forms  (1) cycles of delayed impulses until the SA nodes fails to conduct to the AV node, & then returns to near normal  (2) characterized by a pattern of only every second, third, or fourth impulse being conducted to the ventricles. • Third-degree block or complete heart block – no impulse is carried over from the pacemaker. Page 265 Rhythm/Conduction Defects  Premature contractions – arrhythmia disorder that occurs when an area of the heart known as an ectopic pacemaker (not the SA node) sparks & stimulates a contraction of the myocardium • Atrial fibrillation – when abnormal impulses from the atria bombard the AV node. • PVCs – originate in the ventricles & cause contractions ahead of the anticipated beat. • Ventricular fibrillation – rhythm breaks down & muscle fibers contract at random, without coordination. Page 265 Types of Heart Surgery  Angioplasty (balloon surgery) = procedure to help open clogged vessels  Cardiac stents = tiny, webbed, stainless steel devices that hold arteries open after an angioplasty.  Coronary bypass = surgically providing a detour or bypass to allow the blood supply to go around the blocked area of a coronary artery.  Transmyocardial laser revascularization (TMR) = the use of lasers to puncture holes in the heart muscle to improve blood flow. Page 266 – 267 Heart Transplants  Used as a last resort  Problems include: • Histocompatibility = matching of tissue type • Organ rejection Page 268 SB Medical Highlights Pacemaker = surgical implanted, battery-operated electronic device that sends electrical impulses to regulate the rhythm of the heart  Cardiac resynchronization therapy = uses a special type of pacemaker to recoordinate the action of both the right & left ventricles of the heart, pacing both ventricles simultaneously.  Defibrillator = used to discharge a strong electrical current through the patient’s heart (internal or external)  Heart pumps = implanted in the abdomen & attached to a weakened heart to help it pump