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Name______________________________________________Date________________ Chapter 1 - The Human Body: Notes Mrs. Peck I. AN OVERVIEW OF ANATOMY AND PHYSIOLOGY (p. 2) A. Anatomy (p. 2) Anatomy- the study of the structure and shape of the body & body parts & their relationships to one another 1. Gross Anatomy- study of large observable structures 2. Microscopic Anatomy- study of cells & tissues of body (as seen thru microscope) Dissection- aimed at helping us understand the f’ns of ea of the various levels of organization, but body works as a whole & is more complex than sum of its parts B. Physiology (p. 2) Physiology- study of how the body & its parts work or function diff. types of physiology eg. neurophysiology, cardiac physiology C. Relationship Between Anatomy and Physiology (p. 2) 1. Anatomical structure determines physiological function eg: digestive system: single long tube from entrance to exit, with twists & turns 2. Anatomy & physiology are separate but closely related concepts. *A slight change in anatomy can have a significant effect on physiology II. LEVELS OF STRUCTURAL ORGANIZATION (pp. 2-7) A. From Atoms to Organisms (pp. 2-3) Every level of the system relies on the smooth workings of the level preceding it Malfunction at any level may have life-threatening consequences 1. Chemical Level- atoms combine to form molecules atom- building blocks of matter 2. Cellular Level- molecules combine to form cells such as smooth muscle cells cell- smallest units of all living things 3. Tissue Level- similar cells combine to form tissues such as smooth muscle tissue tissue- groups of similar cells that have a common function eg: epithelial, connective, muscular, neural II. LEVELS OF STRUCTURAL ORGANIZATION (pp. 2-7) 2 A. From Atoms to Organisms (pp. 2-3) 4. Organ Level- differing tissues combine to form organs organ- structure that is composed of two or more tissue types & performs a specific function for the body eg: such as a blood vessel made of epithelial, smooth, and connective tissues 5. Organ System Level- differing organs combine to form organ systems organ system- group of organs that cooperate to accomplish a common purpose eg: digestive: includes esophagus, stomach, small & large intestine, colon ect. each organ has their job to do organs work together to move food thru system: breaking it down & absorbing nutrients 6. Organismal Level- many organs systems combine to form organisms highest level of structural organization eg: human being II. LEVELS OF STRUCTURAL ORGANIZATION (pp. 2-7) 3 B. Organ System Overview (pp. 3-7) Organ systems have a primary f’n, but all are closely interrelated & impact each oth. discuss f’nal relationship b/w muscles & bones, respiratory & cardiovascular systems 1. Integumentary System- external covering for body, vitamin D synthesis, cutaneous reception, sweat and oil gland secretion skin, the external covering of the body waterproofs body cushions & protects deeper tissues from injury excretes salts & urea via perspiration helps regulate body temperature 2. Skeletal System- protect & support deeper movement, hematopoiesis, mineral storage consists of bone, cartilages, ligaments, & joints supports body provides a framework that muscles use to cause movement protective function eg: skull protects brain hematopoiesis- formation of blood cells within cavities of skeleton bones act as a storehouse for minerals 3. Muscular System- manipulation of environment, locomotion, facial expression, maintains posture, and produces heat muscles have one f’n: to contract (shorten) -allows locomotion -maintains posture -produces heat 3 Types: 1. Skeletal Muscles - large fleshy muscles attached to bones 2. Cardiac Muscle- heart muscle 3. Smooth Muscle- surround blood vessels & hollow organs move fluids (blood, urine) or other substances (food) along definite pathways within the body 4. Nervous System- fast-acting response to internal and external stimuli, activation of muscles and glands fast-acting control system consists of brain, spinal cord, nerves, and sensory receptors respond to irritants or stimuli .....outside of body (light, sound, temp changes) ........inside of body (decreases in oxygen) 1. sensory receptors detect changes 2. send messages via nerve impulse to CNS (brain & spinal cord) 3. CNS assesses info and responds by activating appropriate body effectors (muscles or glands) 5. Endocrine System- secretion of hormones which regulate growth, reproduction, metabolism controls body activities (slower than nervous system) endocrine glands produce hormones (molecules) & release to blood glands: pituitary thyroid parathyroid adrenals thymus pancreas pineal ovaries testes 6. Cardiovascular System- transportation of blood which carries oxygen, CO2 , nutrients, and wastes consists of heart and blood vessels blood is used as transporting fluid carries oxygen, nutrients, hormones, & other substances to and from tissues white blood cells and chemicals in blood protect body from bacteria, toxins, tumors heart acts as a pump that moves blood thru vessels 4 7. Lymphatic System- returns leaked fluid to blood, disposes of debris, houses white blood cells for immunity consists of lymphatic vessels, lymph nodes, spleen, tonsils, ect complementary role to the cardiovascular system lymphatic vessels return fluid leaked from blood to blood vessels lymph nodes (& oth. lymphatic organs) cleanse blood & house immunity cells 8. Respiratory System- maintains blood oxygen & removes carbon dioxide via lung air sacs consists of nasal passages, pharynx, larynx, trachea, bronchi, and lungs within lungs are alveoli that exchanges gases with blood supplies body with oxygen & removes carbon dioxide 9. Digestive System- breaks down ingested food for absorption, eliminates undigested foods as feces consists of oral cavity, esophagus, stomach, small & large intestine, & rectum includes liver which secretes bile wh/ breaks down fats includes pancreas which secretes digestive enzymes a tube running thru the body from mouth to anus role: 1. break down food & deliver nutrients to blood to be dispersed thru body 2. reclaim water from food bolus 10. Urinary System- eliminates nitrogenous wastes; regulates water, electrolyte, and acid-base balance of blood consists of kidneys, ureters, bladder, & urethra called the excretory system removes nitrogen-containing waste (urea) from break down of proteins maintaining the body’s water & salt balance regulates the acid-base balance of the blood 11. Reproductive System- production of viable offspring a. Male- consists of testes, scrotum, penis, accessory glands, & duct system testes produce sperm & male sex hormones b. Female- consists of ovaries & female duct system female duct system consists of uterine tubes, uterus, & vagina ovaries produce eggs & female sex hormones fertilization of egg by sperm dev of fetus in uterus mammary glands to nourish newborn III. MAINTAINING LIFE (pp. 7-9) A. Necessary Life Functions (pp. 7-9) many organ systems attribute to these life functions 1. Maintaining Boundaries- keep inside distinct from outside each cell has cell membrane to keep its boundary skin maintains whole body boundary (protects from environment) 2. Movement- performed by muscular system wh/ is attached to the skeletal system movement of blood, food, urine thru cardiovascular, digestive, & urinary 3. Responsiveness (irritability)- ability to sense changes in env. & react to them nervous system plays primary role in this life f’n 5 III. MAINTAINING LIFE (pp. 7-9) A. Necessary Life Functions (pp. 7-9) 7 4. Digestion- breaking down ingested food into simple molecules nutrients absorbed into blood & are transported thru-out body 5. Metabolism- chemical reactions that occur within body cells catabolism- breaking down complex substances into simpler anabolism- making larger substances from smaller ones respiration- using oxygen to break down glucose to make ATP regulated mostly by the endocrine hormones 6. Excretion- removal of wastes from the body urinary system- removes nitrogenous waste digestive system- removes undigested food (feces) 7. Reproduction- production of offspring (regulated by endocrine system) production of new cells for growth or repair 8. Growth- increase in size thru cell production cell production rate greater than cell destruction rate Every life function relies on multiple systems eg: digestion, metabolism III. MAINTAINING LIFE (pp. 7-9) B. Survival Needs (p. 9) 8 nutrients- chemicals used for energy and cell building 1. Nutrients (food)- supplies energy and building blocks for cell production carbohydrates- major energy source glucose starch- polymers of glucose glycogen- 2 glucose molecules bonded....stored in liver proteins- used for cell and enzyme production lipids- (fats) used for cell production energy reserve insulation of body and organs vitamins and minerals- used for biochemical reactions 2. Oxygen- used in respiration (break down of glucose into ATP) 3. Water- provides fluid base for body secretions and excretions base of blood most abundant chemical substance in body ( 60%- 80% of body weight) obtained thru ingestion loss via perspiration, evaporation form lungs, & body excretion III. MAINTAINING LIFE (pp. 7-9) B. Survival Needs (p. 9) 9 4. Body Temperature- humans are endothermic....must maintain constant temp (~98°F) heat generated via muscle activity death occurs if temperature varies too much temp drops- metabolic reactions slow temp raises- metabolic reactions occur rapidly proteins denature (break down) 5. Atmospheric Pressure- force exerted on body by weight of the air breathing dependent upon ATM pressure gas exchange dependent....therefore metabolism dependent Inhalation: diaphragm contracts....increases volume of lungs..decreases lung pressure higher ATM pressure than inside lungs.....air rushes into area of low pressure Expiration (exhalation): diaphragm relaxes...decrease lung volume....increases pressure inside lungs higher internal lung pressure than ATM pressure....air rushes out of lungs Describe the physiological effects of working outside on a 100° F day and compare that to being outside on a day that is below freezing. How does body compensate & maintain homeostasis? Even though our bodies are not exposed to extremes of heatstroke or frostbite, they are still in a constant state of flux, balancing between a range of “normal” values that are rarely static IV. HOMEOSTASIS (pp. 9-11) 10 homeostasis- the body’s ability to maintain relatively stable internal conditions even though the external env. is continuously changing A. Homeostatic Control Mechanisms (p. 10-11) 1. Receptor- stimulus response via afferent pathway 2. Control Center- determines set point and analyzes incoming information to determine appropriate response 3. Effector- response via efferent pathway 4. Negative Feedback Mechanisms- heart rate, blood pressure, breathing rate, blood glucose net effect of response is to shut off original stimulus or reduce its intensity chief regulators of homeostasis under normal healthy conditions. A rise in any given value (blood pH, heart rate, blood pressure) precipitates a reaction to lower it, until such time as it becomes too low, causing negative feedback to initiate responses to raise it again. eg: thermostat in room & HVAC system 5. Positive Feedback mechanisms- blood clotting, childbirth more rare than negative feedback mechanisms eg: childbirth involves an ever-increasing buildup of responses that trigger the next response until they bring about the culmination of a major event like a nuclear reaction, positive feedback involves a series of chain reactions of ever-increasing magnitude B. Homeostatic Imbalance (p. 11) condition that can result in disease aging- body becomes less efficient at maintaining homeostasis increasing illness, disease, and effects of aging V. THE LANGUAGE OF ANATOMY (pp. 11-20) 11 A. Anatomical Position (p. 11) - body is erect with the feet parallel & the arms hanging at the sides with the palms facing forward B. Regional Terms (pp. 12-13, fig. 1.5) 1. Anterior Body Landmarks a. abdominal- anterior body trunk inferior to ribs b. acromial- point of shoulder c. antecubital- anterior surface of elbow d. axillary- armpit e. brachial- arm f. buccal- cheek area g. carpal- wrist h. cervical- neck region i. coxal- hip j. crural- leg k. digital- fingers, toes l. femoral- thigh m. fibular- lateral part of leg n. inguinal- area where thigh meets body trunk; groin o. nasal- nose area p. oral- mouth q. orbital- eye area r. patellar- anterior knee s. pelvic- area overlying the pelvis anteriorly t. pubic- genital region u. sternal- breastbone area v. tarsal- ankle region w. thoracic- chest x. umbilical- navel V. THE LANGUAGE OF ANATOMY (pp. 11-20) B. Regional Terms (pp. 12-13 fig. 1.5) 2. Posterior Body Landmarks a. calcaneal- heel of foot b. cephalic- head c. deltoid- curve of shoulder formed by large deltoid muscle d. femoral- thigh e. gluteal- buttock f. lumbar- area of back between ribs & hips g. occipital- posterior surface of head h. i. j. olecranal- posterior surface of elbow popliteal- posterior knee area sacral- area between hips k. scapular- shoulder blade region l. sural- posterior surface of lower leg; calf m. vertebral- area of spine n. plantar- sole of the foot (actually on the inferior body surface not posterior) Activity 1. locate radial, brachial, carotid, femoral, popliteal, & pedal pulses using tactile and stethoscope methods. Activity 2. Play “simon-says” with anatomical terms Activity 3. Pin the tail on the person using cards with anatomical terms V. THE LANGUAGE OF ANATOMY (pp. 11-20) C. Directional Terms (p. 14; Table 1.1) 13 used to explain exactly where one body structure is in relation to another learn as opposites 1. superior- toward the head end or upper part of a structure or the body; above 2. inferior- away from the head end or toward the lower part of a structure or the body, below 3. anterior (Ventral)- toward or at the front of the body; in front of 4. posterior (Dorsal)- toward or at the backside of the body; behind 5. medial- toward or at the midline of the body; on the inner side of 6. lateral- away from the midline of the body; on the outer side of 7. intermediate- between a more medial and a more lateral structure 8. proximal- close to the origin of the body part or the point of attachment of a limb to the body trunk 9. distal- farther from the origin of a body part or the point of attachment of a limb to the body trunk 10. superficial-toward or at the body surface 11. deep- away from the body surface; more internal ventral and anterior are synonymous in humans; not the case in four-legged animals. ventral refers to the “belly” of an animal and is the inferior surface of the four-legged animal dorsal and posterior are synonymous in humans; not the case in four-legged animals dorsal refers to the “back” of an animal and is the superior surface of the four-legged animal V. THE LANGUAGE OF ANATOMY (pp. 11-20) 14 D. Body Planes and Sections (p. 13 & 17; Figure 1.6) section- a cut through body wall, organ, or tissue 1. sagittal section- lengthwise (longitudinal) division into right & left parts a. midsagittal section- right & left parts have equal size median section 2. frontal section - lengthwise (longitudinal) division into anterior & posterior parts coronal section 3. transverse (horizontal) section - cross-sectional division into superior & inferior parts cross section E. Body Cavities (pp. 17-18; Figure 1.8) 15 1. Dorsal Body Cavity- protection of delicate central nervous system neurons a. Cranial Cavity - superior; brain & pituitary gland b. Spinal Cavity - inferior; spinal cord 2. Ventral Body Cavity-much larger than dorsal cavity (thoracic & abdominopelvic cavities) a. Thoracic Cavity - superior; trachea, lungs, heart diaphragm - dome-shaped muscular division b/w thoracic & abdominal cavities mediastinum - separates lungs into right & left cavities b. Abdominopelvic Cavity - (no true separation b/w abdominal & pelvic cavities) i. Superior Abdominal Cavity - stomach, liver, intestines, other organs ii. Inferior Pelvic Cavity - reproductive organs, bladder, rectum E. Body Cavities (pp. 17-18; Figure 1.8) 16 2. Ventral Body Cavity iii. Abdominopelvic Quadrants - 4 (used by medical personnel) (1) Right Upper Quadrant (2) Right Lower Quadrant (3) Left Upper Quadrant (4) Left Lower Quadrant iv. Abdominopelvic Regions - 9 (1) Umbilical Region (used by anatomists) centermost region (2) Epigastric Region superior to the umbilical region (above stomach) (3) Hypogastric (Pubic) Region inferior to umbilical region (hypo- low) (4) Right Iliac (inguinal) Region lateral to hypogastric region (iliac sup. hip bone) (5) Left Iliac (inguinal) Region lateral to hypogastric region (iliac sup. hip bone) (6) Right Lumbar Region lateral to umbilical region (7) Left Lumbar Region lateral to umbilical region (8) Right Hypochondriac Region (9) Left Hypochondriac Region lateral to epigastric region (chondro- cartilage) lateral to epigastric region (chondro- cartilage) *activity: use tape to make planes, attach signs of 9 regions