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Treatment of Psychological Disorders History Psychological Therapies Biological Therapies Effectiveness Specific Disorder-Treatment Matches Old-Fashioned Causes & “Cures” Possession by demons Prehistoric Trephination In league with Satan Up to 1700 Exorcism Torture Starvation Humor imbalance From Greeks until 1800s Bloodletting Purging Whirling Illness Middle ages until 1800’s Confinement in asylums, often dungeon-like prisons History: 1800’s to 1950 Humanitarian Reform Movement (1800’s) “Inmates” begin to be housed in more standard living conditions Hysteria and general paresis Hysteria cured by Freud (1890’s) Psychological approach to treatment General paresis caused by syphilis (1913) Neuropsychiatric disorder affecting central nervous system – Presents with psychotic-like symptoms Biological approach to treatment Mental hospital inpatient population grows to 600,000 in 1950’s (see slide 5) History: 1950’s to present Discovery of antipsychotics in 1950’s Deinstitutionalization begins in 1960’s and continues until today 40,000 mental hospital inpatients remain (see slide 5) Some reasons for deinstitutionalization Introduction of antipsychotics Criticism of mental hospitals Community care movement Reduce costs to state governments Some negative consequences of deinstitutionalization 16% - 50% of incarcerated prisoners have a mental disorder The range in percentages depend on criteria for mental disorder classification 1/3-1/2 of homeless have mental disorders Jack Nicholson in “One Flew over the Cuckoo’s Nest” Antipsychotic Drugs & Inpatients Psychological Therapies (Psychotherapy) Psychodynamic Therapies Humanistic Therapies Behavioral Therapies Cognitive Therapies Group-Therapy Approaches Psychodynamic Therapies I The goal is to uncover and resolve conflicting thoughts, feelings, and intentions Insight: an understanding of one’s own psychological processes Free association Dream analysis: manifest vs. latent content Hypnosis Analysis of resistance Resistance is the barriers to free association and treatment in general that the patient creates. Catharsis: recovery into consciousness of repressed mental contents causes release of psychic energy and the melting away of associated symptoms Psychodynamic Therapies II Therapeutic alliance Patient-Therapist relationship Comfort level Nonjudgmental and empathetic listener Transference Patients bring enduring interpersonal patterns into their relationship with their therapist Positive vs. negative Countertransference Therapists may experience emotional responses to their patients Therapist must themselves undergo therapy in order to detect and handle these feelings Humanistic Therapies Removing impediments to personal growth Client-Centered Therapy – Carl Rogers Warm and Caring Relationship Empathy Unconditional Positive Regard Reflection Gestalt Therapy – Fritz Perls Empty chair technique Imagine that the person to whom you wish to express your feelings is sitting in the empty chair Two chair technique Place two sides of a dilemma in two different chairs and express each side while in that chair Behavioral Therapies I Focus is on altering symptoms rather than exploring their meaning Operant-Conditioning Techniques Reward and Punishment Biofeedback Behavior modification Token economies To treat headaches or chronic pain (see next slide) Skills Training Social skills – Assertiveness training ADHD Biofeedback & Tension Headaches Sensors on the head detect muscle activity System converts signal to visual display Patient watches the display, tries to reduce tension signal Muscle tension reduced Behavioral Therapies II Classical conditioning techniques are often used when there is a specific feared object (as in phobias) or desired object (as in addictions) Flooding Confronting a fearful stimulus without negative consequences will lead to extinction of the dysfunctional conditioned emotional response Systematic Desensitization Associating positive feelings with a feared stimulus – Relaxation training, construction of fear hierarchy, and gradual exposure Aversive Conditioning: associating negative feelings with a desirable, but unhealthy, object (see next slide) Aversion Therapy for Alcoholism Alcohol is paired with a chemical that causes nausea and vomiting Straightforward classical conditioning Cognitive Therapies I Rational-Emotive Behavior Therapy Albert Ellis A form of cognitive therapy in which people are confronted with their irrational, maladaptive beliefs. Common beliefs that are irrational and selfdefeating – I have to be liked by everyone – I have to be perfect at what I do – Everyone gets what they deserve Therapeutic devices – Step out of character – “How to refuse to be ashamed of anything” – Try new behaviors to see that these behaviors won’t bring your life crashing down around you Cognitive Therapies II A-B-C’s of Emotional Distress Disorders often occur because of self- defeating beliefs Activating Event - Beliefs - Consequences Rational-emotive therapy helps people change these beliefs Cognitive Therapies III Cognitive Therapy Aaron Beck A form of psychotherapy in which people are taught to think in more adaptive ways. Address cognitive distortions Catastrophizing: belief that was has happened was so awful or what will happen will be so terrible that you won’t be able to stand it Overgeneralization: seeing a single negative event as a never-ending pattern of defeat Address negative triad (world, self, future) in depression World: interpret events unfavorably Self: Does not like themselves Future: Regard future pessimistically Therapeutic devices Asking “What’s the evidence?” “Are these facts or interpretation?” “Is there another way to look at the situation?” Triggering distress during therapy so that it can be interpreted Keeping diaries or logs and doing reading assignments Group Therapy Approaches 4 to 10 people meet with one or two therapists usually once a week for 2 hours Successful group members can instill hope in newcomers Discovering that others have similar problems can relieve shame and guilt Group members talk about individual problems, but also gain insight from group processes in that people often interact with others in such a way that it is revealing Biological Therapies Drug Therapies (uses psychotropic medications) (also known as Psychopharmacology) Antianxiety Drugs “Tranquilizers” Can treat generalized anxiety Barbituates Work, but are highly addictive Benzodiazepines Increase activity of GABA, an inhibitory neurotransmitter Examples (trade names in parentheses) Diazepam (Valium) Chlordiazepoxide (Librium) Alprazolam (Xanax) Negative side effects Drowsiness; dangerous when combined with alcohol After stopping, two-week rebound period of greater anxiety Can be psychologically and physically addictive Can cause memory loss Buspirone (Trade name: BuSpar) Antidepressants Tricyclic antidepressants Block reuptake of serotonin and norepinephrine Improvement of 40-50% over placebo Imipramine (Trade name: Tofranil) Placebo: Any medical intervention designed to work through the power of suggestion A pill that does not contain any medically active ingredients can reduce symptoms by 20-40% MAO (monoamine oxidase) inhibitors MAO is an enzyme that breaks down serotonin So, if you inhibit this enzyme, you will increase the amount of serotonin in the brain Effective when personality disorders are also present Selective serotonin reuptake inhibitors (SSRI’s) Fluoxetine (Trade name: Prozac) Antipsychotic Drugs “Major tranquilizers” Known as this because of sedating effects Also known as “neuroleptics” Reduce positive symptoms, like hallucinations and delusions By inhibiting dopamine Do not do much for negative symptoms Examples (trade name in parentheses) Chlorpromazine (Thorazine) Haloperidol (Haldol) Clozapine (Clozaril) Risperidone (Risperdal) Side effects of thorazine: tardive dyskinesia Involuntary twitching in tongue, face, neck, and jaw Occurs in patients who have taken Thorazine for several years Irreversible Other Medical Interventions Electroconvulsive Therapy (ECT) Electric-shock treatments that often relieve severe depression by triggering seizures in the brain. Psychosurgery The surgical removal of portions of the brain for the purpose of treating psychological disorders. After, antipsychotic medications were introduced, psychosurgery was no longer a serious consideration Lobotomy Severing tissue in a cerebral lobe, typically the frontal lobe Produced severe side effects (see Phineas Gage) Treatment Effectiveness Psychotherapy Disorder-Treatment matches Usefulness of Psychotherapy Two ways to evaluate the usefulness of psychotherapy Effectiveness studies (this slide) vs. efficacy studies (next slide) Effectiveness studies Assessment of treatment outcomes under relatively less controlled conditions 1994 Consumer Reports Survey (N=2900) 2004 Consumer Reports Survey (N=3000) Somewhat improved to much improved – 86% Fairly satisfied to highly satisfied – 89% 28% rise in the use of psychological medications Medication plus psychotherapy produces the best outcome, followed by psychotherapy alone, and then drug therapy alone Reasons to be critical of the use of effectiveness studies Subjective measure No comparison to group that had problems but did not receive treatment Efficacy studies Assessment of treatment outcomes under controlled conditions Random assignment of subjects to conditions Therapists trained to adhere to manual Standardized length of treatment Summary of 475 efficacy studies (Smith et al., 1980) The figure below shows that the average psychotherapy patient is better off than 80% of untreated patients Are some psychotherapies better? On average, across all disorders, all therapies are equally effective (Sloane et al., 1977; Elkin et al., 1989) However, for some disorders, certain types of therapy tend to be more successful than others Two common, nonspecific factors at work in all types of psychotherapy Supportive relationship with caring therapist gives patients reason for hope The opportunity for a patient to open up can have healing power Pennebaker Anxiety Disorder & Treatment Match For specific phobias The sources of anxiety are better addressed with cognitivebehavioral therapy (CBT) than with medication Systematic Desensitization Virtual treatments can reduce fear responses For social phobia SSRI’s help, but CBT is better For panic disorder Treatments often combine medication and CBT, but relapse is less with CBT For obsessive-compulsive disorder (OCD) For tic-related OCD, SSRI’s and dopamine receptor blockers For non-tic-related OCD, oxytocin regulation Exposure and response prevention therapy Exposure & Response Prevention Another type of behavioral therapy Woman with handwashing compulsion Baseline Instruction Response prevention cycle After a few cycles, the woman was washing less often and getting fewer urges to wash Hand washing Urges Depression & Treatment Match Psychological medications MAO-inhibitors, tricyclics, and SSRI’s provide relief to 6070% of depressed persons Cognitive-behavioral therapy (CBT) Just as effective psychological medications Targets the automatic irrational thoughts that accompany depression Medication plus CBT is most effective Seasonal Affective Disorder Responds to phototherapy Exercise helps depression too Electroconvulsive therapy (ECT) The single most effective treatment for severe depression, and it saves lives, negative public views notwithstanding Transcranial magnetic stimulation (TMS) Bipolar Disorder & Treatment Match Lithium is “indispensable” for the treatment of bipolar disorder Reduces bipolar mood swings Especially effective at calming mania Less effective in reducing the severity of the depressive mood swings – For this reason, an antidepressant is often prescribed in addition to lithium Takes awhile (3-4 weeks) to “kick in” Side effects are unpleasant during this period Highly toxic Only 20% of bipolar patients who maintain their medications experience relapse But many patients discontinue medication, perhaps because of the “intoxicating pleasure” of manic states Schizophrenia & Treatment Match Antipsychotic medications are indispensable for the treatment of schizophrenia But significant sedative and motor side effects, resembling Parkinson’s disease, make treatment unpleasant for many patients In addition, patients show little improvement in social skills Psychosocial treatments Improve functioning beyond drug treatments Social skills training Most schizophrenic patients improve as they get older Professionals Involved in Therapy Clinical Psychologists Psychiatrists Psychiatric (or clinical) social worker Psychiatric nurse Counseling Psychologists Psychoanalysts Others offering therapy (paraprofessionals) Crisis intervention Pastoral Counselors Community outreach Where People Turn for Help Orientations of Psychotherapists Can Personality Disorders Be Treated? Dialectical Behavior Therapy Is Most Successful for Borderline Personality Disorder Antisocial Personality Disorder Is Difficult to Treat The Use of Medication to Treat Adolescent Depression Is Controversial Fewer than 30 percent of children who have mental health problems receive any type of treatment Twice as many of those taking SSRIs reported having suicidal thoughts (4 percent) as those taking a placebo (2 percent) None of the children or adolescents committed suicide The FDA voted in 2004 to require manufacturers to add to their product labels a warning that antidepressants increase the risk of suicidal thinking and behavior in depressed children and adolescents The Use of Medication to Treat Adolescent Depression Is Controversial The previous slide displayed the results of the TADS study All treatment groups experienced a reduction in thoughts of suicide compared with the baseline However, participants in the Prozac group were twice as likely to have serious suicidal thoughts or intentions compared with those undergoing other treatments Although prescribing drugs without CBT might be cost effective, it may not be in the best interests of depressed children Children with ADHD Can Benefit from a Variety of Approaches Methylphenidate (ritalin) targets under active brains and reduces negative behaviors (see Fig. 14.29 and Fig. 15.23) Side effects and lack of long-term efficacy limit the utility of ritalin Behavioral Treatments, though time-consuming, augment medication and help social skills, academics, and family relationships Autistic Children Benefit from a Structured Treatment Approach Generalization of skills must be taught explicitly Applied Behavior Analysis (ABA) is time intensive but raises IQ points by 20 onaverage The long-term prognosis for autism is poor