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Biochemistry Vocabulary Review Molecules that have the same chemical formula but different structure are called… Isomers The energy needed to get a chemical reaction started. Activation Energy Large molecules made mostly of C and H that do not mix well with water are called… Lipids Amino acid The monomer of proteins The smallest unit of molecules that make up polymers, or building blocks, are called… Monomers Carbohydrate A macromolecule made up of sugars Macromolecules made of nucleotides that contain C, H, O, N, S and P are called… Nucleic acids Dehydration synthesis A reaction where two molecules are joined by the removal of water The monomer of a nucleic acid consisting of a sugar molecule, a phosphate, and a base is called… Nucleotide Enzyme A protein that acts as a biological catalyst The bond between two amino acids is called a… Peptide bond Hydrolysis A reaction where a larger molecule is broken down by adding water Large molecules that are made from many smaller, repeating molecules called monomers are known as… Polymers Protein A macromolecule made up of amino acids The molecule on which an enzyme works is called the… Substrate