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Haploid gametes (n 23) Egg cell n n Sperm cell FERTILIZATION MEIOSIS Multicellular diploid adults (2n 46) 2n MITOSIS and development © 2010 Pearson Education, Inc. Diploid zygote (2n 46) Key Haploid (n) Diploid (2n) Figure 8.12 – Sexual reproduction may convey an evolutionary advantage by: • Speeding adaptation to a changing environment • Allowing a population to more easily rid itself of harmful genes © 2010 Pearson Education, Inc. Meiosis • http://highered.mcgrawhill.com/sites/0072495855/student_view0/chapter28/animation__how_ meiosis_works.html • http://highered.mcgrawhill.com/sites/0072495855/student_view0/chapter28/animation__stage s_of_meiosis.html • http://highered.mcgrawhill.com/sites/0072495855/student_view0/chapter28/animation__uniqu e_features_of_meiosis.html • http://highered.mcgrawhill.com/sites/0072495855/student_view0/chapter28/animation__matur ation_of_the_follicle_and_oocyte.html • http://highered.mcgrawhill.com/sites/0072495855/student_view0/chapter28/animation__rando m_orientation_of_chromosomes_during_meiosis.html © 2010 Pearson Education, Inc. NONDISJUNCTION IN MEIOSIS II NONDISJUNCTION IN MEIOSIS I Meiosis I Nondisjunction: Pair of homologous chromosomes fails to separate. Meiosis II Nondisjunction: Pair of sister chromatids fails to separate. Gametes n1 n1 n–1 Abnormal gametes © 2010 Pearson Education, Inc. Number of n – 1 chromosomes n1 n–1 Abnormal gametes n n Normal gametes Figure 8.20-3 © 2010 Pearson Education, Inc. Table 8.1 Which of the following is an actual difference between mitosis and meiosis? 1. A single cell is divided into two cells in mitosis and four cells in meiosis. 2. Mitosis produces haploid cells, and meiosis produces diploid cells. 3. Mitosis involves two cellular divisions, and meiosis has only one cellular division. 4. The chromosomes replicate before mitosis and meiosis, but in meiosis they replicate again between the first and second divisions. © 2010 Pearson Education, Inc. The diagram on the right represents the cell cycle through time of a eukaryotic organism. Which of the four phases of the cell cycle is the most variable in length of time, depending on the type of cell? 1. G1 phase 2. S phase 3. G2 phase 4. M phase © 2010 Pearson Education, Inc.