Download Nanotechnology and Heath: The use of nanostructure DDS

Nanotechnology and Heath: The use of nanostructure DDS system in tissue engineer,
cancer treatment and other diseases
Antonio.C.Tedesco, Ph.D.
Photobiology and Photomedicine Research Group
FFCLRP- São Paulo University, Ribeirão Preto, S. P., Brasil [email protected]
The ability of the body to restore its integrity subsequent to many different kinds of
injury is essential for the maintenance of life. Any living organism, in its constant interaction
with the environment and with other organisms, eventually faces adverse situations, such as
harsh climatic conditions, infections or many other diseases that might bring about the need to
repair or reconstitute its body structures in order to preserve the original tissue function.
Today there are a new field of medicine that are in charge of the development of new
techniques and therapeutic approaches to repair and restore the cell , tissue and body integrity
know generally a as Tissue Engineering. It can be defined as a therapeutic approach that use
biomaterials in association with small molecules, cells lines, genes, or other biological
material to maintain, replace, or repair organ function with the objective of correcting the
underlying pathology. Most of the work developed until now are based on the use of
engineered cells, tissues, associated with synthetic materials that can potentially extend and
improve a patient’s life. Three basics approaches have been used, 1) organ transplants, 2)
surgical reconstruction associate with the use of mechanical devices, and, more recently, 3)
cellular therapy. Cancer and many other non-oncological diseases has been used
nanotechnology associate with the development of drug delivery system to improve the
treatment protocol and also to establish new in vivo studies models. The association of tissue
engineering models, nanotechnology and photo process (drugs working by light activation)
will be discuss in this in this tutorial, presenting the future advantages of these combination
not only applicable to cancer treatment, but also to other diseases, as tuberculosis, PBmicose,
and epilepsy.
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