Role of the p21 Protein in the Fanconi Anemia Pathway
... – If the kinetics of D2 mono-Ub and p21 expression are similar, this would be suggestive that both proteins are involved in the same cellular process. ...
... – If the kinetics of D2 mono-Ub and p21 expression are similar, this would be suggestive that both proteins are involved in the same cellular process. ...
Physical map of the aromatic amine and m-toluate
... Bacterial strains and plasmids. The Pseudomonasputida and Escherichia coli strains and the plasmids used and constructed during the course of this investigation are detailed in Table 1. Media and culture conditions. Nutrient agar and nutrient broth were prepared according to the manufacturers' instr ...
... Bacterial strains and plasmids. The Pseudomonasputida and Escherichia coli strains and the plasmids used and constructed during the course of this investigation are detailed in Table 1. Media and culture conditions. Nutrient agar and nutrient broth were prepared according to the manufacturers' instr ...
Get - Wiley Online Library
... The bases of certain nucleotides can bind to others via hydrogen bonds. These noncovalent interactions (called base pairing) allow different nucleic acid molecules to recognize each other. Generally, G pairs with C and A with T (in DNA) or U (in RNA). Thus, two nucleic acid polymers containing compl ...
... The bases of certain nucleotides can bind to others via hydrogen bonds. These noncovalent interactions (called base pairing) allow different nucleic acid molecules to recognize each other. Generally, G pairs with C and A with T (in DNA) or U (in RNA). Thus, two nucleic acid polymers containing compl ...
7nQ Jj I f NO "7^07 - UNT Digital Library
... to understand. It offers a detailed look at all the components of genetics. It contains study questions as well as summaries for each chapter to provide an even better way to retain the knowledge from my lectures. The course that I have outlined is intended for a junior or senior college student. So ...
... to understand. It offers a detailed look at all the components of genetics. It contains study questions as well as summaries for each chapter to provide an even better way to retain the knowledge from my lectures. The course that I have outlined is intended for a junior or senior college student. So ...
Detection of chromosome 2 and chromosome 7 within X-ray
... lagging chromosomes induced by spindle poisons is micronucleation, which occurs after mitosis during nuclear membrane formation. The cytokinesis block method using cytochalasin B allows detection of cells which have undergone division, as binucleated cells, and micronuclei occurring in such cells ca ...
... lagging chromosomes induced by spindle poisons is micronucleation, which occurs after mitosis during nuclear membrane formation. The cytokinesis block method using cytochalasin B allows detection of cells which have undergone division, as binucleated cells, and micronuclei occurring in such cells ca ...
Chromosomes in Saccharomyces cerevisiae
... and URA3 markers, originally carried by the plasmid, mitotically stable. Therefore, continuous growth in leucine-free medium enriches for integrants. We determined that the integrant TA1145-I arose from recombination between the LEU2 sequences on YLp16 and the nonfunctional leu2 gene on chromosome I ...
... and URA3 markers, originally carried by the plasmid, mitotically stable. Therefore, continuous growth in leucine-free medium enriches for integrants. We determined that the integrant TA1145-I arose from recombination between the LEU2 sequences on YLp16 and the nonfunctional leu2 gene on chromosome I ...
International Journal of Antimicrobial Agents Mechanism of drug
... The role of mobile genetic elements in imparting multiple drug resistance to a clinical isolate of Vibrio fluvialis (BD146) was investigated. This isolate showed complete or intermediate resistance to all of the 14 antibiotics tested. Polymerase chain reaction (PCR) revealed the presence of a class 1 ...
... The role of mobile genetic elements in imparting multiple drug resistance to a clinical isolate of Vibrio fluvialis (BD146) was investigated. This isolate showed complete or intermediate resistance to all of the 14 antibiotics tested. Polymerase chain reaction (PCR) revealed the presence of a class 1 ...
Cytogenetics with special reference to domestic animals
... of short, repeated sequences are shown in black. Mouse centromeres (indicated in black in B) are located at the ends of chromosomes; no known genes lie beyond the centromere on any mouse chromosome. For the most part, human centromeres, indicated by constrictions, occupy more internal positions on c ...
... of short, repeated sequences are shown in black. Mouse centromeres (indicated in black in B) are located at the ends of chromosomes; no known genes lie beyond the centromere on any mouse chromosome. For the most part, human centromeres, indicated by constrictions, occupy more internal positions on c ...
Jigsaw handout - the Biology Scholars Program Wiki
... binds to lac repressor and causes a conformation change that alters the structure of lac repressor so that it cannot bind to DNA. Therefore, in the presence of lactose, lac repressor does not bind to the operator and RNA polymerase can transcribe the genes in the lac operon. Case study (homework or ...
... binds to lac repressor and causes a conformation change that alters the structure of lac repressor so that it cannot bind to DNA. Therefore, in the presence of lactose, lac repressor does not bind to the operator and RNA polymerase can transcribe the genes in the lac operon. Case study (homework or ...
No Slide Title
... Cyclin-cdks are themselves regulated by phosphorylation of the cdk • Cyclin associated cdk is still inactive as a kinase • Threonine at position 160 (T160) of cdk2 has to be phosphorylated for the kinase to be active. The cdk activating kinase (CAK) is actually cyclin H-cdk7 • Threonine at position ...
... Cyclin-cdks are themselves regulated by phosphorylation of the cdk • Cyclin associated cdk is still inactive as a kinase • Threonine at position 160 (T160) of cdk2 has to be phosphorylated for the kinase to be active. The cdk activating kinase (CAK) is actually cyclin H-cdk7 • Threonine at position ...
CHROMOSOMES AND DISEASE
... history when many new lands and races were being discovered and described for the first time. Thus the name suggested for people with this specific disability was Mongolism. Today the disorder is more appropriately referred to as Down syndrome or trisomy 21. The disorder results from an abnormality ...
... history when many new lands and races were being discovered and described for the first time. Thus the name suggested for people with this specific disability was Mongolism. Today the disorder is more appropriately referred to as Down syndrome or trisomy 21. The disorder results from an abnormality ...
A molecular method for assessing meiofauna diversity in marine
... majority of meiofauna in most samples as well as the most easily recognized taxa, and makes the need for taxonomic expertise unnecessary (Raffaelli and Mason, 1981). This technique assumes that copepods are more sensitive to pollution than nematodes, and that nematodes will be the most abundant mei ...
... majority of meiofauna in most samples as well as the most easily recognized taxa, and makes the need for taxonomic expertise unnecessary (Raffaelli and Mason, 1981). This technique assumes that copepods are more sensitive to pollution than nematodes, and that nematodes will be the most abundant mei ...
Figure 20-6
... • During metaphase I the bivalents attach via their kinetochores to spindle microtubules, and migrate to the spindle equator • The presence of paired homologues at the equator is a feature specific to meiosis • The bivalents are randomly oriented, and homologues are held together only by chiasmata © ...
... • During metaphase I the bivalents attach via their kinetochores to spindle microtubules, and migrate to the spindle equator • The presence of paired homologues at the equator is a feature specific to meiosis • The bivalents are randomly oriented, and homologues are held together only by chiasmata © ...
Action
... Antimetabolites are compounds that prevent the formation or utilization of a normal cellular metabolite. Most antimetabolites are enzymes inhibitors. The rate-limiting enzymes of nucleotide biosynthesis are often the primary target for the antimetabolites. Antimetabolites can also inhibit other enzy ...
... Antimetabolites are compounds that prevent the formation or utilization of a normal cellular metabolite. Most antimetabolites are enzymes inhibitors. The rate-limiting enzymes of nucleotide biosynthesis are often the primary target for the antimetabolites. Antimetabolites can also inhibit other enzy ...
Gene Detection Systems Catalog
... systems used in genetic research technology applications worldwide. Gene Link, Inc. is privately held biotechnology company incorporated in the State of New York dedicated to fundamental and applied research on genetic/biomedical projects relating to gene mapping, localization, detection and marketi ...
... systems used in genetic research technology applications worldwide. Gene Link, Inc. is privately held biotechnology company incorporated in the State of New York dedicated to fundamental and applied research on genetic/biomedical projects relating to gene mapping, localization, detection and marketi ...
lntraclonal mating in Trypanosoma brucei is
... DNA of trypanosomes, has shown that one DNA component (maxicircles) is inherited uniparentally, while the other (minicircles) is inherited from both parents (Gibson & Garside, 1990). The generation of hybrid kDNA networks implies that both cellular and mitochondrial fusion occur during genetic excha ...
... DNA of trypanosomes, has shown that one DNA component (maxicircles) is inherited uniparentally, while the other (minicircles) is inherited from both parents (Gibson & Garside, 1990). The generation of hybrid kDNA networks implies that both cellular and mitochondrial fusion occur during genetic excha ...
mMESSAGE mMACHINE® Kit User Guide
... to be transcribed. Circular plasmid templates will generate extremely long, heterogeneous RNA transcripts because RNA polymerases are very processive. It is generally worthwhile to examine the linearized template DNA on a gel to confirm that cleavage is complete. Since initiation of transcription is ...
... to be transcribed. Circular plasmid templates will generate extremely long, heterogeneous RNA transcripts because RNA polymerases are very processive. It is generally worthwhile to examine the linearized template DNA on a gel to confirm that cleavage is complete. Since initiation of transcription is ...
Science and the Dead - Council for British Archaeology
... years and are likely to continue to do so. Increasingly, the different techniques are used in conjunction (e.g. DNA and stable isotopic techniques for personal identification). Hence, there has also been an increase in requests for the application of multiple destructive techniques. Some large organi ...
... years and are likely to continue to do so. Increasingly, the different techniques are used in conjunction (e.g. DNA and stable isotopic techniques for personal identification). Hence, there has also been an increase in requests for the application of multiple destructive techniques. Some large organi ...
Getting Started With Gel Electrophoresis
... from red algae. When dissolved in hot water and allowed to cool, the solution turns into a gel because long agarose molecules hydrogen bond together, creating a large, threedimensional network trapping the water. This gel can then be placed in an electrophoresis chamber, which along with a power sup ...
... from red algae. When dissolved in hot water and allowed to cool, the solution turns into a gel because long agarose molecules hydrogen bond together, creating a large, threedimensional network trapping the water. This gel can then be placed in an electrophoresis chamber, which along with a power sup ...
Specialized Transduction by Bacteriophage P22 in Salmonella typhimurium: Genetic and Physical Structure of the Transducing Genomes and the Prophage Attachment Site.
... chromosome. By examining DNA heteroduplexes in the electron microscope, we found that DNA molecules from P22pro-I and P22pro-3 each contain a substitution which adds length to the composite genome making the intracellular replicated genome too long to fit into a single phage particle. In this respec ...
... chromosome. By examining DNA heteroduplexes in the electron microscope, we found that DNA molecules from P22pro-I and P22pro-3 each contain a substitution which adds length to the composite genome making the intracellular replicated genome too long to fit into a single phage particle. In this respec ...
Rearrangements in the Human T-Cell-Receptor Â
... disease in a very small proportion (0.01-0.02%) of HTLV-Iinfected individuals (1) imply that additional genetic changes may be required for the onset of the disease. Nonrandom chromosome translocations are a nearly constant feature of human leukemias and lymphomas. In 1985, we reported re arrangemen ...
... disease in a very small proportion (0.01-0.02%) of HTLV-Iinfected individuals (1) imply that additional genetic changes may be required for the onset of the disease. Nonrandom chromosome translocations are a nearly constant feature of human leukemias and lymphomas. In 1985, we reported re arrangemen ...
TRIzol Reagent
... BCP (1-bromo-2 chloropropane) can be used in the place of chloroform. BCP has a higher density. Because of its higher density, the interface is more compact and therefore the aqueous layer is more easily recovered. (see Chomczynski, P. and Mackey, K. (1995) Anal. Biochem. 225, 163-164). The quantity ...
... BCP (1-bromo-2 chloropropane) can be used in the place of chloroform. BCP has a higher density. Because of its higher density, the interface is more compact and therefore the aqueous layer is more easily recovered. (see Chomczynski, P. and Mackey, K. (1995) Anal. Biochem. 225, 163-164). The quantity ...
DNA supercoil
DNA supercoiling refers to the over- or under-winding of a DNA strand, and is an expression of the strain on that strand. Supercoiling is important in a number of biological processes, such as compacting DNA. Additionally, certain enzymes such as topoisomerases are able to change DNA topology to facilitate functions such as DNA replication or transcription. Mathematical expressions are used to describe supercoiling by comparing different coiled states to relaxed B-form DNA.As a general rule, the DNA of most organisms is negatively supercoiled.