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Oral cancer is one of the leading cancers around the world and
Oral cancer is one of the leading cancers around the world and

... ideal molecular markers. DNA methylation frequently leads to transcriptional changes in both tumor suppressor genes and oncogenes. Some of the techniques developed thus far enable the identification of novel cancer genes altered by DNA methylation alone or in combination with genetic events. They ma ...
Phylogeny of the Primates
Phylogeny of the Primates

... As promised, you are going to get your chance to create a phylogenetic tree from some molecular clock data. We are going to give you some mutation differences in DNA. This is just like the bird phylogeny we did. Below is a table of REAL data. This date represents difference in DNA. It is obtained by ...
Unit 4
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... 11. Explain how viruses may cause disease symptoms, and describe some medical weapons used to fight viral infections. Damage or kill cells. In response to a viral infection, lysosomes may release hydrolytic enzymes. Be toxic themselves or cause infected cells to produce toxins. Cause varying degrees ...
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DNA Workshop
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Genetics Genetics, a discipline of biology, is the science of genes
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... DNA from bacteria. (A plasmid is circular DNA that is not part of a chromosome and can replicate independently.) Ligation is illustrated below. The DNA that results is called recombinant DNA. 3. In transformation, the recombinant DNA is inserted into a living cell, usually a bacterial cell. Changing ...
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... strand, the strands are said to be complementary. DNA copies itself through the process of replication: The two strands of the double helix unzip, forming replication forks. New bases are added, following the rules of base pairing (A with T and G with C). Each new DNA molecule has one original stran ...
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Bacterial Genetics
Bacterial Genetics

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Extrachromosomal DNA



Extrachromosomal DNA is any DNA that is found outside of the nucleus of a cell. It is also referred to as extranuclear DNA or cytoplasmic DNA. Most DNA in an individual genome is found in chromosomes but DNA found outside of the nucleus also serves important biological functions.In prokaryotes, nonviral extrachromosomal DNA is primarily found in plasmids whereas in eukaryotes extrachromosomal DNA is primarily found in organelles. Mitochondrial DNA is a main source of this extrachromosomal DNA in eukaryotes. Extrachromosomal DNA is often used in research of replication because it is easy to identify and isolate.Extrachromosomal DNA was found to be structurally different from nuclear DNA. Cytoplasmic DNA is less methylated than DNA found within the nucleus. It was also confirmed that the sequences of cytoplasmic DNA was different from nuclear DNA in the same organism, showing that cytoplasmic DNAs are not simply fragments of nuclear DNA.In addition to DNA found outside of the nucleus in cells, infection of viral genomes also provides an example of extrachromosomal DNA.
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