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Homologous recombination
Homologous recombination

... Retrotransposition mechanisms using DNA targets. The COXI gene of strain 1+t20 (top) contains both the donor aI1 intron (hatched) and the 5 848 ectopic site in intron 5 (open rectangle) The mechanism on the left begins with reverse splicing into the ectopic site in double-stranded DNA. Inefficient n ...
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The Hereditary Material - Advanced

... of the R strain bacteria still occurred. They found that the proteases, which remove proteins from cells, and ribonuclease, which break apart RNA, did not affect transformation, but an enzyme preparation of deoxyribonuclease, which breaks down DNA, destroyed the transforming power. Together, these r ...
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... 2. As the DNA molecule unzips, RNA polymerase assembles RNA nucleotides using one strand of the DNA as a template. 3. Only the 3’  5’ template strand of DNA is transcribed. The RNA complimentary strand grows in the 5’  3’ direction. ...
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The origin of life molecules Nucleotide(核苷酸)

... poly(A) tails. (2) The hairpin structure that likely forms around the miRNA sequence of the pri-miRNA acts as a signal for digestion by a double-stranded (ds) ribonuclease (Drosha) to produce the precursor miRNA (Pre-miRNA). (3) Exportin-5 mediates nuclear export of pre-miRNAs. (4) A cytoplasmic dsR ...
How Do Chromosomes Carry Information?
How Do Chromosomes Carry Information?

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... chromosomes) fuses with egg cell (containing 23 chromosomes) • The nucleus of the sperm cell is injected into the egg cell • After the sperm fertilizes the egg, a zygote containing 23 pairs of chromosomes (46 total chromosomes) is formed ...
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... Sexual reproduction gives variation because, when gametes fuse, one of each pair of alleles comes from each parent. Chromosomes are made up of DNA. A gene is a small section of DNA. DNA can be used to identify individuals in a process known as DNA fingerprinting. ...
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... explaining the link between a change in the genetic code and a change in phenotype. I can explain how a mutation can lead to a new allele by linking genotype and phenotype. I can discuss why mutations are only passed on if they occur in gametes. ...
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... our bodies that we just don’t understand.  Performing experiments in humans, however, is highly unethical.  We are still able to make insights into human development and disease by studying similar genes in model organisms. Many of the basic principles of biology that were first identified in model ...
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Extrachromosomal DNA



Extrachromosomal DNA is any DNA that is found outside of the nucleus of a cell. It is also referred to as extranuclear DNA or cytoplasmic DNA. Most DNA in an individual genome is found in chromosomes but DNA found outside of the nucleus also serves important biological functions.In prokaryotes, nonviral extrachromosomal DNA is primarily found in plasmids whereas in eukaryotes extrachromosomal DNA is primarily found in organelles. Mitochondrial DNA is a main source of this extrachromosomal DNA in eukaryotes. Extrachromosomal DNA is often used in research of replication because it is easy to identify and isolate.Extrachromosomal DNA was found to be structurally different from nuclear DNA. Cytoplasmic DNA is less methylated than DNA found within the nucleus. It was also confirmed that the sequences of cytoplasmic DNA was different from nuclear DNA in the same organism, showing that cytoplasmic DNAs are not simply fragments of nuclear DNA.In addition to DNA found outside of the nucleus in cells, infection of viral genomes also provides an example of extrachromosomal DNA.
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