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Genetics of Cancer
Genetics of Cancer

Document
Document

... Genes that inhibit cell division are inactivated. – Mutation in a gene that halts the cell cycle in G1 causes retinoblastoma. – Mutation in p53, a gene that promotes apoptosis if a cell has damaged DNA, leads to a variety of cancers. – Mutation in BRCA1, involved in tumor suppression and DNA repair, ...
Goal 3.01 Quiz 1
Goal 3.01 Quiz 1

... A. Some DNA mutates as the cells are developing. B. Some DNA functions in males, while other DNA functions only in females. C. Some DNA is active in certain cells, while other DNA is active in other cells. D. Some DNA recombines to form different proteins than the DNA found in the original cells. ...
Review for Post Exam 10 on iLearn
Review for Post Exam 10 on iLearn

... 2. Why is DNA called a universal code? 3. What macromolecule is DNA and RNA? 4. How are genes coded for in DNA 5. Why does DNA replicate? 6. How is DNA inherited? 7. Describe how DNA replicates? (makes a copy of itself) Using the words: DNA helicase, DNA polymerase, base pair rule, semi conservative ...
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Chapters Bacteria, viruses, prions

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DNA Technology

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Transformed (cancer) cells
Transformed (cancer) cells

... – Ionizing radiation removes electrons, generating reactive ions that cause DNA damage – UV radiation causes pyrimidine dimer formation in DNA ...
Cancer is generally understood as a genetic or cellular disease
Cancer is generally understood as a genetic or cellular disease

Recombinant DNA I
Recombinant DNA I

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Study guideCh8

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Genetic Engineering
Genetic Engineering

... • 3. A Plasmid holding foreign DNA is inserted into the DNA and is connected by the ligase. (sticky end to sticky end) • 4. The recombinant DNA is inserted into a bacterium which carries out its function inside the larger organism. • 5. When the DNA becomes active it directs the body to construct di ...
Goals of pharmacogenomics
Goals of pharmacogenomics

...  Collection of all RNA transcripts (m, t, rRNA)  Tissue specific gene expression  Which genes are on/off  Varies with cell type, environment, disease, etc..  Use microarrays ...
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Quiz 3 Key - UW Canvas

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docx Probes and fingerprint matching Card sort or vocab

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Slide 1

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hox genes - WordPress.com
hox genes - WordPress.com

... •PROMOTER REGIONS are associated with genes and help initialize transcription of the gene into a protein •GENETIC SWITCHES play a role regulating the EXPRESSION of genes ...
Genetics
Genetics

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... WES analyses the total genome, or protein-coding sequence. Most of the known disease causing genes lie within this part of the genome. ...
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Compendium 11 Learning Outcomes • Describe the structure and

... • Describe the structure and functions of proteins • Describe the structure of nucleic acids, differentiating between DNA and RNA • Define the components of a nucleotide • Differentiate between the nucleotide bases of DNA and RNA • Explain what the genetic code is and what it is coding for • Describ ...
Biology 303 EXAM III
Biology 303 EXAM III

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1 Genetics (BIL-250) Review Questions #1 (2

... (6-2) What are the 4 main types of amino acids? How many amino acids are there total? How many stop codons exist? (6-3) Illustrate a peptide bond? Label the N- and C- termini. (6-4) What distinguishes primary, secondary, tertiary, and quaternary protein structure? (6-5) What is a framewhift mutation ...
Dioxyribose Nucleic Acid
Dioxyribose Nucleic Acid

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Honors Biology Final Exam-‐Part 2-‐Semester 2

... 38.    Any  trait  that  better  enables  an  organism  to  survive  in  its  environment   39.    Effect  that  occurs  after  a  disaster  that  drastically  reduces  population  size.   40.    A  structure  which  has  no  functi ...
Understanding DNA
Understanding DNA

... 2. Draw the cell and label the ff structures: a. cell membrane Note: Follow guidelines on b. chromosomes Making Diagrams ...
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Cancer epigenetics



Cancer epigenetics is the study of epigenetic modifications to the genome of cancer cells that do not involve a change in the nucleotide sequence. Epigenetic alterations are as important as genetic mutations in a cell’s transformation to cancer, and their manipulation holds great promise for cancer prevention, detection, and therapy. In different types of cancer, a variety of epigenetic mechanisms can be perturbed, such as silencing of tumor suppressor genes and activation of oncogenes by altered CpG island methylation patterns, histone modifications, and dysregulation of DNA binding proteins. Several medications which have epigenetic impact are now used in several of these diseases.
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