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L8 Bacterialgenetics 7e
L8 Bacterialgenetics 7e

... Repair mechanisms • Wrong nucleotide inserted – Proofreading – Mismatch repair ...
Genetics in the New Millennium: From Plants to People
Genetics in the New Millennium: From Plants to People

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Epigenetics and the exposomes: Obesity and beyond
Epigenetics and the exposomes: Obesity and beyond

... In reproduction, certain genes are turned on while others are turned off in the process of imprinting. In the case of imprinting, even though there are two copies of the gene, only one copy is expressed and there is no substitute functional allele. For this reason, imprinting makes the imprinted gen ...
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... Transferring to other organisms, e.g. -- insulin production to bacteria -- herbicide/ insect resistance to plants -- crop yield & nutritional value (e.g. ‘golden rice’) -- biofuel (e.g., rape seed oil) ...
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... A. the form of the enzyme that is involvedin promoter recognition B. the form of the enzyme that is involvedin productive elongation C. caused by phosphorylation of theN-terminus of the largest subunit D. is also found as a feature of RNApolymerase III The transcription factor called TFIID a. is a g ...
DNA Structure: Deoxyribonucleic acid
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Cancer epigenetics



Cancer epigenetics is the study of epigenetic modifications to the genome of cancer cells that do not involve a change in the nucleotide sequence. Epigenetic alterations are as important as genetic mutations in a cell’s transformation to cancer, and their manipulation holds great promise for cancer prevention, detection, and therapy. In different types of cancer, a variety of epigenetic mechanisms can be perturbed, such as silencing of tumor suppressor genes and activation of oncogenes by altered CpG island methylation patterns, histone modifications, and dysregulation of DNA binding proteins. Several medications which have epigenetic impact are now used in several of these diseases.
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