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Topic 4: Genetics - Peoria Public Schools
Topic 4: Genetics - Peoria Public Schools

Simple tandem repeats in mammalian genomes
Simple tandem repeats in mammalian genomes

PowerPoint-Präsentation
PowerPoint-Präsentation

... found 4.624 genes, which showed differences in gene expression and 19.261 different DNA methylation sites. Between closer related cells like naive and activated/memory cells of the same lymphocyte subtype (CD4+ T-cells) the number decrease to 638 genes and 9.412 sites. Comparing monocytes against T- ...
Genetic Engineering
Genetic Engineering

... -genetic material changed by other than random natural breeding. -gene transfer-moving a gene from one organism to another. -these require skill and knowledge to be carried out properly ...
epigenetics
epigenetics

... SLIDE 11 Genetic imprinting Certain autosomal* genes have seemingly unusual inheritance patterns. "Imprinted genes" don't rely on traditional laws of Mendelian genetics, which describe the inheritance of traits as either dominant or recessive. In Mendelian genetics, both parental copies are equally ...
MolecularBiology1APLab6
MolecularBiology1APLab6

... • Enzymes that cut DNA at very specific base sequences (often palindromes) • Make blunt or sticky ends • Evolved to combat invasive DNA from viruses • Does not cut bacterium’s DNA because it’s missing correct DNA sequence • Different bacterial strains have different RE ...
Mutation and DNA Repair
Mutation and DNA Repair

... a CH3 group is attached to the 5 position on the ring. When 5-methyl cytosine is spontaneously deaminated, it is converted to thymine, a standard DNA base. Replication leads to a base change: one daughter stays a C-G base pair while the other is converted to T-A. Over evolutionary time, this has led ...
Genetics Study Guide Answers
Genetics Study Guide Answers

... Recombination between linked genes comes about for what reason? A) Mutation on one homolog is different from that on the other homolog. B) Independent assortment sometimes fails because Mendel had not calculated appropriately. C) When genes are linked they always "travel" together at anaphase. D) C ...
Gene expression and DNA microarrays
Gene expression and DNA microarrays

... • Each PCR product represents a single gene. • 4074 genes of 4101 on the array. • Printed on Corning CMT-GAPS slides. • 4 E. coli controls, each represented 15-20 times on the array. ...
Chapter 7.1 - Fredericksburg City Schools
Chapter 7.1 - Fredericksburg City Schools

... If the statement is true, write true. If the statement is false, change the underlined word(s) to make the statement true. ...
Biotechnology
Biotechnology

cd-epi.center
cd-epi.center

Study Guide
Study Guide

Genetics
Genetics

... homozygous • Human blood types illustrate other mechanisms of inheritance ...
Eucharyotic Chromatin Organization
Eucharyotic Chromatin Organization

... Why is the control of gene expression more complex in eukaryotes than prokaryotes ? (2)  4) cells that require cell specialization or ...
Slide 1
Slide 1

... This table shows the amino acids that are specified by different mRNA codons. Most amino acids are coded for by more than one codon and so many substitution mutations have no effect on the final polypeptide. A mutation in the DNA triplet CCA into CCG would change the codon in the mRNA from GGU to G ...
Sun exposure is very harmful and can lead to serious and painful
Sun exposure is very harmful and can lead to serious and painful

Genetic Engineering
Genetic Engineering

... 1. Isolate the foreign DNA by using _____restriction enzymes___ that cleave (cut) the donor DNA at very specific places 2. Vectors transfer the donor DNA into the host a. mechanical vectors = Carry DNA into a cell, micropipette or metal bullet b. biological vectors = virus or bacterial plasmid (____ ...
Ghost in Your Genes Viewing Guide
Ghost in Your Genes Viewing Guide

... But not all switches are epigenetic; some are genetic. That is, other genes within the chromosome turn genes on or off. In an animal's embryonic stage, these gene switches play a main role in laying out the animal's basic body plan and perform other early functions; the epigenome begins to take over ...
Genetic Exchange - Pennsylvania State University
Genetic Exchange - Pennsylvania State University

... “Jumping Genes” • Transposable elements (insertion sequences and transposons) can tranfer copies of themselves within or to other DNA molecules (chromosome, pDNA, or vDNA). • Antibiotic resistance genes rapidly spread within and between bacterial populations by composite transposons carried on F fac ...
W09micr430Lec17 - Cal State LA
W09micr430Lec17 - Cal State LA

... AP site, usually on the 5’ side This generates 3’-hydroxyl end, which is extended by DNA pol I as the 5’-exonuclease activity of this enzyme removes a portion of damaged DNA ahead. DNA ligase seals the nick. ...
Gene Technology
Gene Technology

... the gene into the cells of a person whose copy of the gene is defective  Disease being now treated with gene therapy  Cancer  Cystic fibrosis  Hemophilia  Rheumatoid arthritis ...
Handout 2: Glossary
Handout 2: Glossary

Slide 1
Slide 1

... Why are identical twins different?  They have the same genome, so WTF?  Base-pair mutations are one way to get genetic ...
L8 Bacterialgenetics 7e
L8 Bacterialgenetics 7e

... Repair mechanisms • Wrong nucleotide inserted – Proofreading – Mismatch repair ...
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Cancer epigenetics



Cancer epigenetics is the study of epigenetic modifications to the genome of cancer cells that do not involve a change in the nucleotide sequence. Epigenetic alterations are as important as genetic mutations in a cell’s transformation to cancer, and their manipulation holds great promise for cancer prevention, detection, and therapy. In different types of cancer, a variety of epigenetic mechanisms can be perturbed, such as silencing of tumor suppressor genes and activation of oncogenes by altered CpG island methylation patterns, histone modifications, and dysregulation of DNA binding proteins. Several medications which have epigenetic impact are now used in several of these diseases.
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