Examining the Process of de Novo Gene Birth
... transcribed into RNA. Until a few years ago, most scientists thought that only genes were transcribed into RNA. In courses, students learn about how meticulously gene transcription is regulated, with the implication that each cell transcribes only the genes that are needed at a given time. It turns ...
... transcribed into RNA. Until a few years ago, most scientists thought that only genes were transcribed into RNA. In courses, students learn about how meticulously gene transcription is regulated, with the implication that each cell transcribes only the genes that are needed at a given time. It turns ...
Metabolic functions of duplicate genes in Saccharomyces cerevisiae
... – In several cases, a single major isoform is essential. – Finally, only 19 of all duplicate families (105) are categorized to exhibit a potential dosage function. ...
... – In several cases, a single major isoform is essential. – Finally, only 19 of all duplicate families (105) are categorized to exhibit a potential dosage function. ...
Chen Lossos - Microarrays in Diffuse Large B-Cell Lymphoma
... the strongest initial evidence for the subcategorization of DLBCL. This study utilized a specialized cDNA array called Lymphochip, which was constructed by selecting genes expressed in lymphoid cells or which were previously reported to be involved in cancer biology. Using an unsupervised hierarchic ...
... the strongest initial evidence for the subcategorization of DLBCL. This study utilized a specialized cDNA array called Lymphochip, which was constructed by selecting genes expressed in lymphoid cells or which were previously reported to be involved in cancer biology. Using an unsupervised hierarchic ...
in plant physiology
... impaired in the pTAC mutants, whereas NEP-dependent transcription is up-regulated. These phenotypes and chloroplast gene expression patterns are reminiscent of those of rpo mutants (Allison et al. 1996; Hajdukiewicz et al. 1997), suggesting a critical role for pTAC proteins in PEP transcription. Aff ...
... impaired in the pTAC mutants, whereas NEP-dependent transcription is up-regulated. These phenotypes and chloroplast gene expression patterns are reminiscent of those of rpo mutants (Allison et al. 1996; Hajdukiewicz et al. 1997), suggesting a critical role for pTAC proteins in PEP transcription. Aff ...
Hox gene regulation by C. elegans sop-3
... acids without clear homologs in other organisms. However, the sequence contains motifs consisting of homopolymeric runs of amino acids found in several other transcriptional regulators, some of which also act in Hox gene regulatory pathways. The genetic properties of sop-3 are very similar to those ...
... acids without clear homologs in other organisms. However, the sequence contains motifs consisting of homopolymeric runs of amino acids found in several other transcriptional regulators, some of which also act in Hox gene regulatory pathways. The genetic properties of sop-3 are very similar to those ...
Title PPAR interprets a chromatin signature of - DR-NTU
... Bioinformatics, Lausanne, Switzerland, 3 Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore ...
... Bioinformatics, Lausanne, Switzerland, 3 Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore ...
Autosomal monoallelic expression in the mouse
... natural killer cell receptors [3-9]. However, we have recently shown that a surprisingly large number of human genes with diverse functions (nearly 10% of approximately 4,000 assessed genes) are subject to this type of random monoallelic expression [10]. For autosomal RMAE, as with X-chromosome inac ...
... natural killer cell receptors [3-9]. However, we have recently shown that a surprisingly large number of human genes with diverse functions (nearly 10% of approximately 4,000 assessed genes) are subject to this type of random monoallelic expression [10]. For autosomal RMAE, as with X-chromosome inac ...
Lecture 15 – PDF
... A. To this point we have considered segregation and assortment of gene pairs that are located on different, non-homologous chromosomes, viz., segregation/assortment from the dihybrid A/a; B/b is expected to yield the following gametes ¼ AB ...
... A. To this point we have considered segregation and assortment of gene pairs that are located on different, non-homologous chromosomes, viz., segregation/assortment from the dihybrid A/a; B/b is expected to yield the following gametes ¼ AB ...
Whole-genome expression analysis of snf swi mutants of
... cause repression of transcription by blocking transcription factor binding (1). In recent years, several studies have shown that the conserved protein complex, Snf兾Swi, can relieve this repression by perturbing the structure of nucleosomes (2). This remodeling probably allows transcription factors t ...
... cause repression of transcription by blocking transcription factor binding (1). In recent years, several studies have shown that the conserved protein complex, Snf兾Swi, can relieve this repression by perturbing the structure of nucleosomes (2). This remodeling probably allows transcription factors t ...
A haploid-specific transcriptional response to
... tions. We used microarray analysis and gene reporter fusions to assess the contributions of ploidy and mating-type to the transcriptional response induced by irradiation. Gamma irradiation generates various types of DNA damage, including double-strand breaks (DSBs). A single unre- 55 paired DSB is d ...
... tions. We used microarray analysis and gene reporter fusions to assess the contributions of ploidy and mating-type to the transcriptional response induced by irradiation. Gamma irradiation generates various types of DNA damage, including double-strand breaks (DSBs). A single unre- 55 paired DSB is d ...
Figure 2 - GEP Community Server
... Prediction Tracks" section); change this to "pack". This track shows the alignment of D. melanogaster cDNAs (complementary DNAs, made by copying the mRNA) that have been sequenced by the Berkeley Drosophila Genome Project (BDGP). Click on the "refresh" button (Figure 2). These two tracks both provid ...
... Prediction Tracks" section); change this to "pack". This track shows the alignment of D. melanogaster cDNAs (complementary DNAs, made by copying the mRNA) that have been sequenced by the Berkeley Drosophila Genome Project (BDGP). Click on the "refresh" button (Figure 2). These two tracks both provid ...
Leukaemia Section t(1;21)(p36;q22) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... Upper panel: normal genomic structures of PRDM16 and RUNX1 (non-coding parts in bleu). A cryptic exon, residing within intron 1 of PRDM16, is indicated in green (speckled). Lower panel: structure of RUNX1-PRDM16 fusion transcripts. Exons are numbered on the basis of consensus gene sequences. Exon si ...
... Upper panel: normal genomic structures of PRDM16 and RUNX1 (non-coding parts in bleu). A cryptic exon, residing within intron 1 of PRDM16, is indicated in green (speckled). Lower panel: structure of RUNX1-PRDM16 fusion transcripts. Exons are numbered on the basis of consensus gene sequences. Exon si ...
Ch 15b
... Inheritance of Organelle Genes • Extranuclear genes are genes found in organelles in the cytoplasm • The inheritance of traits controlled by extranuclear genes depends on the maternal parent because the zygote s cytoplasm comes from the egg • The first evidence of extranuclear genes came from stu ...
... Inheritance of Organelle Genes • Extranuclear genes are genes found in organelles in the cytoplasm • The inheritance of traits controlled by extranuclear genes depends on the maternal parent because the zygote s cytoplasm comes from the egg • The first evidence of extranuclear genes came from stu ...
A programme for the construction of a lambda phage
... developmental programme might have some valuable lessons for developmental biologists working on more complex systems. This review will present a simple account of the key steps in the lytic and lysogenic pathways, with emphasis on the control mechanisms governing co-ordination and commitment to a p ...
... developmental programme might have some valuable lessons for developmental biologists working on more complex systems. This review will present a simple account of the key steps in the lytic and lysogenic pathways, with emphasis on the control mechanisms governing co-ordination and commitment to a p ...
PDF
... modern vertebrate clusters apparently arose by serial duplication of a 13 member cluster with subsequent deletions. As a result, the homologous genes in different clusters (referred to as paralogues) are more similar to each other than they are to adjacent genes in the same cluster. Paralogous genes ...
... modern vertebrate clusters apparently arose by serial duplication of a 13 member cluster with subsequent deletions. As a result, the homologous genes in different clusters (referred to as paralogues) are more similar to each other than they are to adjacent genes in the same cluster. Paralogous genes ...
Powerpoint - Blood Journal
... repression of ferritin translation in low-iron conditions is similar to mechanism of iron-mediated regulation of erythroid ALA synthase (e-ALAS) gene. ...
... repression of ferritin translation in low-iron conditions is similar to mechanism of iron-mediated regulation of erythroid ALA synthase (e-ALAS) gene. ...
Fulltext PDF - Indian Academy of Sciences
... TMV at 48 hours post inoculation (hpi) using RNA extraction reagent kit according to the manufacturer’s protocols (Tiangen Biotech, Beijing). The concentration and quality of extracted RNA were evaluated by 1.0% agarose gel electrophoresis and Nanodrop 2000 spectrophotometer (Thermo, USA), respectiv ...
... TMV at 48 hours post inoculation (hpi) using RNA extraction reagent kit according to the manufacturer’s protocols (Tiangen Biotech, Beijing). The concentration and quality of extracted RNA were evaluated by 1.0% agarose gel electrophoresis and Nanodrop 2000 spectrophotometer (Thermo, USA), respectiv ...
Chpt19_TxnlRegEuk.doc
... some genes and then stall at a pause site. The classic example are heatshock genes in Drosophila, but other cases are also known. b. These genes are activated by release of stalled polymerases to elongate. In the case of the heat shock genes, this requires heat shock transcription factor (HSTF). The ...
... some genes and then stall at a pause site. The classic example are heatshock genes in Drosophila, but other cases are also known. b. These genes are activated by release of stalled polymerases to elongate. In the case of the heat shock genes, this requires heat shock transcription factor (HSTF). The ...
Chapter 11 Powerpoint
... • Transcription cannot proceed until the pre-initiation complex has been constructed at the promoter • Construction of the pre-initiation complex is a stepwise recruitment process that eventually brings in RNA pol II • Multiple transcription factors are involved, know them and their functions • The ...
... • Transcription cannot proceed until the pre-initiation complex has been constructed at the promoter • Construction of the pre-initiation complex is a stepwise recruitment process that eventually brings in RNA pol II • Multiple transcription factors are involved, know them and their functions • The ...
Genomic imprinting of a placental lactogen gene in Peromyscus
... organism. For this reason there has been intense debate about the function of imprinting (Moore and Haig 1991; Hurst 1997). While the more than 30 imprinted genes discovered to date have a variety of biochemical functions and many are widely expressed, mutations in the genes disproportionately affec ...
... organism. For this reason there has been intense debate about the function of imprinting (Moore and Haig 1991; Hurst 1997). While the more than 30 imprinted genes discovered to date have a variety of biochemical functions and many are widely expressed, mutations in the genes disproportionately affec ...
The Origin of the Jingwei Gene and the Complex Modular Structure
... Jingwei (jgw) is the first gene found to be of sufficiently recent origin in Drosophila to offer insights into the origin of a gene. While its chimerical gene structure was partially resolved as including a retrosequence of alcohol dehydrogenase (Adh), the structure of its non-Adh parental gene, the ...
... Jingwei (jgw) is the first gene found to be of sufficiently recent origin in Drosophila to offer insights into the origin of a gene. While its chimerical gene structure was partially resolved as including a retrosequence of alcohol dehydrogenase (Adh), the structure of its non-Adh parental gene, the ...
Chromatin Structure Is a Focus for Regulation 30.2
... – Euchromatin: Majority chromatin is in its extended (decondensed) state during interphase, only condenses during mitosis. – Heterochromatin: Remains highly condensed even in interphase. Accounts for the dark staining regions seen in interphase chromatin. Heterochromatin is further classified as: • ...
... – Euchromatin: Majority chromatin is in its extended (decondensed) state during interphase, only condenses during mitosis. – Heterochromatin: Remains highly condensed even in interphase. Accounts for the dark staining regions seen in interphase chromatin. Heterochromatin is further classified as: • ...