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RNAi and RNAa - The Yin and Yang of RNAome
RNAi and RNAa - The Yin and Yang of RNAome

Journal of Advanced Computing (2012) 1
Journal of Advanced Computing (2012) 1

Text S1 unc-46 The unc-46 gene encodes a protein required for the
Text S1 unc-46 The unc-46 gene encodes a protein required for the

... neurons is controlled by the transcription factor UNC-30 [2]. The C. elegans cis element of acr-14 directed expression in one pair of cells in the lateral ganglion in the head, AVAL/R, and neurons (median count was 41) in the ventral cord (Figure 3B). Based on the number of cells and the morphology ...
Lluís Millán Ariño GENOMIC DISTRIBUTION AND FUNCTIONAL SPECIFICITY OF
Lluís Millán Ariño GENOMIC DISTRIBUTION AND FUNCTIONAL SPECIFICITY OF

... 3.1. All H1 variants are non-specifically present at gene promoters and are depleted from transcription start sites (TSS) in active genes In our first attempt to elucidate H1 variant distribution in the genome, we tested occupancy in specific loci corresponding to diverse genomic features. Therefore ...
CorrelateTalk
CorrelateTalk

... • In this talk, we’ll consider the case of DNA copy number and gene expression measurements on a single set of samples. • Sparse CCA gives us a tool that can be used to answer the question: Can we identify a small set of gene expression measurements that is correlated with a region of DNA copy numbe ...
TCE - University of Arizona
TCE - University of Arizona

... Dig-labeled gC1qBP cDNA was hybridized to 1 or 2 ug of ...
L12_RNAseq
L12_RNAseq

... • RNA is extracted from tissue, cleaved into fragments a few hundred nucleotides long, and then converted to a complementary DNA (cDNA) library (Wilhelm & Landry, 2009). • Sequencing adaptors are ligated to both ends of each fragment, and the products are sequenced using any highthroughput method su ...
Candidate gene prioritization with Endeavour
Candidate gene prioritization with Endeavour

... and are therefore more suited for diseases of unknown etiology. These methods rely on disease relevant keywords, or on complementary disease specific experimental data sets. For instance, the Génie web server ranks genes using a textmining approach that is fed with user-selected keywords and can be ...
The Arabinose Operon (http://faculty.clintoncc.suny.edu/faculty
The Arabinose Operon (http://faculty.clintoncc.suny.edu/faculty

... Ara C also binds to other sites within the operon, inhibiting transcription of the three structural genes. The genes therefore are normally not active. ...
Lecture 21: Macroevolution
Lecture 21: Macroevolution

... • involved in gross alterations in phenotype • Affect develop’t of cuticular structures from imaginal disks • in all animal phyla • share # of common characteristics • e.g. antennapedia ...
microarray activity - Blue Valley Schools
microarray activity - Blue Valley Schools

... room to tape other such cDNA’s under the same probe sequence). This set represents DNA hybridization. Be sure to obey the rules of base complementarity, and remember that double stranded DNA is antiparallel. For this activity you may assume the temperature is high enough so that there must be at lea ...
MODELING GENE EXPRESSION FROM MICROARRAY
MODELING GENE EXPRESSION FROM MICROARRAY

... (state) is simplified to being either completely “on” or “off”. These states are often represented by the binary values 1 and 0, respectively, and the state of a gene is determined by a Boolean function of the states of other genes. The functions can be represented in tables, or as rules. And exampl ...
Non-Mendelian Genetics
Non-Mendelian Genetics

... Characterized by genes carried on the X or Y chromosomes. • If the genes are on the • Those carried on the X y, they are called are more abundant holandric. Ex: Ear hair • EX: Muscular Dystrophy ...
Document
Document

... expression profiles and transcriptional control. ...
linkage-recomb2
linkage-recomb2

... genotypes appear in the F2 generation. Different linked genes are inherited as a group rather than as separate units. The closer 2 genes are on a chromosome, the more likely it is that they will be inherited together. ...
Drosophila-Mega-Review
Drosophila-Mega-Review

The angiotensin-converting enzyme (ACE) gene family ofAnopheles
The angiotensin-converting enzyme (ACE) gene family ofAnopheles

... twenty-six exons and two promoters, and has clearly arisen by gene duplication [4]. The somatic promoter drives expression of the larger protein (exons 1–12 and exons 14–26), which consists of two very similar domains connected in tandem by a short inter-domain peptide. Each domain possesses a funct ...
File
File

... A mutant has been isolated that produces all three enzymes at the same level as induced cells do, even without any yuctose in the medium. ...
Investigation 1: Identify the Transcriptional Unit
Investigation 1: Identify the Transcriptional Unit

... 2. To navigate to the genomic region surrounding the tra gene, enter "contig1:9,65011,000" into the "enter position or search terms" field located just above the displayed tracks and then click on the “go” button. As you learned in the previous module, you can also use the buttons in the navigation ...
Iron-sulfur Clusters in RNA Polymerase: A New Role for an Ancient
Iron-sulfur Clusters in RNA Polymerase: A New Role for an Ancient

... However, mutant strains with RNAP containing variant subunit D exhibited a slow growth phenotype. Western blot analysis indicated the slow growth phenotype is not due to significant differences in RNAP levels. Partial purification of RNAP followed by Western blot analysis and non-specific transcript ...
Microarray Analysis -- Image Processing and Filter Design
Microarray Analysis -- Image Processing and Filter Design

... Microarray is a new technology of molecular biology research. It is an excellent tool to monitor gene transcription for thousands of genes at a time. The first step of this technique involves spotting known sequences on a substrate, which in most cases are glass slides or nylon membranes. This is fo ...
portable document (.pdf) format
portable document (.pdf) format

... “Oncogene outliers” are those genes which show systematically increased expressions in disease samples, but only for a small number of cancer samples. Since the discovery of the existence of oncogenes, several proposals have been made for detecting differentially expressed (DE) genes in two-class mi ...
Gene Section ANXA1 (annexin A1)  Atlas of Genetics and Cytogenetics
Gene Section ANXA1 (annexin A1) Atlas of Genetics and Cytogenetics

... However the regulation from glucocorticoid (GC) appear to be dependent upon an activation involving NFIL-6 or AP1 (Solito et al., 1998a; Solito et al., 1998b). The GC mediated regulations confirm the original studies which proposed ANXA1 as mediator of the glucocorticoid action (Flower, 1988). In mo ...
Analysis of Microarray Genomic Data of Breast Cancer Patients
Analysis of Microarray Genomic Data of Breast Cancer Patients

Ding, Yi : Singular Value Decomposition applied to the building of class predictor
Ding, Yi : Singular Value Decomposition applied to the building of class predictor

... expression data on a genomic scale (Spellman et. al 1998, Eisen et. al 1998, Golub et. al 1999). The outputs of the experiments are expression profiles either sampled at different times or from different sources (patients belonging to different phenotype). This has a profound impact on the study of ...
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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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