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Gene Section SSX2 (Synovial Sarcoma, X breakpoint 2) in Oncology and Haematology
Gene Section SSX2 (Synovial Sarcoma, X breakpoint 2) in Oncology and Haematology

... Synovial sarcoma (SS) is an aggressive soft tissue tumor that inflicts young adults between 15 and 40 years of age. Though its cell of origin is still unknown, it is thought to be a mesenchymal stem cell. Synovial sarcomas most frequently arise in the para-articular areas, but are also known to appe ...
bicoid - Blumberg Lab
bicoid - Blumberg Lab

... • ultimately, you will need to know this stuff for MCAT and GRE • may as well learn it now while we are here to explain the parts that may not be completely clear ...
Ch.15 Study Guide
Ch.15 Study Guide

... FIGURES 15.4) Each chromosome has hundreds or thousands of genes. Linked genes do not assort independently.  Independent assortment of chromosomes and crossing over produce genetic recombinants (pp. 273-275, FIGURES 15.5) Recombinant offspring, which exhibit new combinations of traits inherited fro ...
Sex chromosome evolution in non
Sex chromosome evolution in non

... in the developing gonads before differentiation. Interestingly, expression is higher in the left gonad, which in female chicken develops to ovary as the right anlage regresses. The predicted amino acid sequence of FET1 does not correspond to any known domain that would be informative to infer a func ...
Several recent reports have suggested a relationship between
Several recent reports have suggested a relationship between

... However, taken together, the research data and population studies suggesting that epigenetic changes with deleterious consequences could result from the application of ART techniques in the human must be taken seriously. Though we must be careful considering technological and etiological causes sepa ...
Lec 10 - Regulation of Gene
Lec 10 - Regulation of Gene

... Each cell of a living organism contains thousands of genes. But all genes do not function at a time. Genes function according to requirements of the cell. Genes control the phenotypic expression of various characters through the production of specific enzymes. Enzymes are special proteins which cata ...
lecture9 - Stanford AI Lab
lecture9 - Stanford AI Lab

Transposable Elements
Transposable Elements

... terminal repeats ; usually the two copies of the repeat are closely related rather than ...
Two Cyp19 (P450 Aromatase) Genes on Duplicated Zebrafish
Two Cyp19 (P450 Aromatase) Genes on Duplicated Zebrafish

... 1996; Chang et al. 1997). Goldfish have at least two forms of cyp19, one expressed in ovaries and the other found in the brain (Tchoudakova and Callard 1998). In the brain, aromatization of androgens into estrogens is an essential step in regulating a variety of physiological and behavioral processe ...
Normalization between a pair of arrays
Normalization between a pair of arrays

... Some regulatory proteins play more general role in initiating transcription (for example the eukaryotic transcription factors of type II or the RNA polymerase itself that is essential for the transcription of all genes). It is considered that dedicated regulatory proteins are those that affect up to ...
Introduction to Bioinformatics.
Introduction to Bioinformatics.

... Sequence Tag. * EST sequencing can identify genes that are ‘missed’ with ab initio gene-finding methods, such as ORF-finder. ...
Gene Regulation
Gene Regulation

... predicted modules. This was expected as this region often contains the promoter of the genes. Surprisingly, there are modules immediately downstream of TSSs. These may represent alternative promoters for initiation downstream from the annotated transcripts. Regions surrounding the sites of terminati ...
MCDB 1041 Activity 3: Thinking about how “linkage” affects the
MCDB 1041 Activity 3: Thinking about how “linkage” affects the

... PART I. Comparing inheritance of genes on the same chromosome (Linkage) to when they are on different chromosomes. In the 1930’s, scientists had the idea that they could figure out where all the genes were on the human chromosomes by following patterns of inheritance. They looked for diseases or tra ...
The Gene Balance Hypothesis: From Classical Genetics to Modern
The Gene Balance Hypothesis: From Classical Genetics to Modern

... female Drosophila and among her progeny found intersexual flies that possessed a mixture of male and female parts (Bridges, 1925). The karyotype of these intersexual flies was composed of two X chromosomes with an otherwise triploid complement of chromosomes. However, flies with only one X chromosom ...
Maternal and paternal genomes contribute equally to the
Maternal and paternal genomes contribute equally to the

... approaches similar to ours but looking much later after fertilization greatly expanded the list of genes with parent-of-origin-specific expression in the endosperm but did not identify such genes in embryos23,24. Thus, the imprinting-like phenomenon that we observed in early embryos is short lived, ...
Mapping strategies for sequence reads (with focus on RNA-seq)
Mapping strategies for sequence reads (with focus on RNA-seq)

... potential donor/acceptor splice sites within neighboring regions are joined ...
Using credibility intervals instead of hypothesis tests in SAGE analysis
Using credibility intervals instead of hypothesis tests in SAGE analysis

... desired credibility stringency. In this example, choosing q = 50% or q = 95% leads to ‘differentially’ conclusion and q = 99% leads to ‘not differentially’, since the last contains Q = 0.5 (equivalent to ratio R = 1) and the others do not. Frame (b) shows method’s behavior at extreme case, when tran ...
Top Ten Ways to Ensure Valid RNAi Data
Top Ten Ways to Ensure Valid RNAi Data

... contrast, another report indicates that siRNAs can silence non-target genes containing as few as 14–15 consecutive complementary nucleotides [3]. Therefore, until we reach a better understanding of siRNA specificity, it is best to allow for at least 2 nucleotide mismatches between an siRNA and all c ...
A multistep epigenetic switch enables the stable
A multistep epigenetic switch enables the stable

... that partial expression is not due to the fact that the deletions shift the a mutant in which these sequences were deleted (cHNL332; Fig. 4c). sequences of upstream genes closer to agn43 (cHNL330; Fig. 2d). The above experiments identified two different partial states. One Together, these data sugge ...
Every Cell Has a Sex - Women`s Health Research Institute
Every Cell Has a Sex - Women`s Health Research Institute

A dioxin sensitive gene, mammalian WAPL, is implicated in
A dioxin sensitive gene, mammalian WAPL, is implicated in

... and 5 0 -CACTTGCGGTGCACGATGGAG-3 0 ; or CYP1A1 specific primers, 5 0 -TTTGGTTTGGGCAAGCGA-3 0 and 5 0 -GTCTAAGCCTGAAGATGC-3 0 . Reaction mixtures were denatured at 95 C for 30 s, then subjected to 40 PCR cycles at either 95 C for 3 s, 68 C for 30 s, and 86 C for 6 s for mWAPL, or 95 C for 3 s, 68 ...
Linkage II
Linkage II

... • Interlocus distance is proportional to the degree of crossing over between. – Little or no crossing over in close genes. – Frequent, even multiple crossovers between distant genes. • Chromosome map, determined from recombination rates, indicates relative locations of genes on a chromosome. ...
The Importance of Epigenetic Phenomena in Regulating Activity of
The Importance of Epigenetic Phenomena in Regulating Activity of

... do not alter the nucleotide sequence of DNA. It can be described as a phenomenon that determines the final functionality of a locus or chromosome without changing the underlying DNA sequence (Goldberg, Allis, and Bernstein 2007). Instead of altering the DNA sequence, epigenetic factors affect how an ...
Archaeal Transcription Initiation - IMBB
Archaeal Transcription Initiation - IMBB

... homologs of the eucaryal TFIIS transcription elongation factors have been identified (Bult et al., 1996), but close homologs of eucaryal transcription regulators have not been detected. Archaeal genomes also contains genes related to the nusA and nusG genes that encode bacterial transcription antite ...
Linked___Genes
Linked___Genes

... B and C are 5 units apart B ____5___C A and C are 10 units apart A ________10 _________C The resulting map is: ...
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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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