Isolation and characterization of Viviparous
... related genes (Suzuki et al., 1997). The multiple domains of ABI3 enable it to function either as an activator or a repressor depending on the promoter context (Zhang et al., 2006b). The N-terminal A1 domain is responsible for ABA-dependent co-activation and repression activities (Hoecker et al., 19 ...
... related genes (Suzuki et al., 1997). The multiple domains of ABI3 enable it to function either as an activator or a repressor depending on the promoter context (Zhang et al., 2006b). The N-terminal A1 domain is responsible for ABA-dependent co-activation and repression activities (Hoecker et al., 19 ...
Gene Section JUN (V-Jun sarcoma virus 17 oncogene homolog (avian))
... JUN is the most important component of AP-1 transcription factors, and its transcriptional activity is possibly attenuated by JUNB or JUND. It has been well accepted that JUN regulates cell proliferation, apoptosis and transformation. JUN promotes cell cycle transition from G1 phase to S phase by up ...
... JUN is the most important component of AP-1 transcription factors, and its transcriptional activity is possibly attenuated by JUNB or JUND. It has been well accepted that JUN regulates cell proliferation, apoptosis and transformation. JUN promotes cell cycle transition from G1 phase to S phase by up ...
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... phalanges respectively. In a foot infected with the Hoxd-L1virus (B), the anterior two digits have a similar structure which includes the two phalanges normally found in the second digit. The anterior metatarsal now arises proximally and has a structure similar to that of the posterior tarsometatars ...
... phalanges respectively. In a foot infected with the Hoxd-L1virus (B), the anterior two digits have a similar structure which includes the two phalanges normally found in the second digit. The anterior metatarsal now arises proximally and has a structure similar to that of the posterior tarsometatars ...
Journal of Molecular Biology
... 1975: Yagil et al.. 1975). whereas a dual role has been suggested for t,he phoR gene product : namely, as a repressor and as an activator in the presence and absence of phosphate, respectively (Garen & Echols. 1962: Wanner B LatterelI. 1980). The phoM gene product acts as an activator that can parti ...
... 1975: Yagil et al.. 1975). whereas a dual role has been suggested for t,he phoR gene product : namely, as a repressor and as an activator in the presence and absence of phosphate, respectively (Garen & Echols. 1962: Wanner B LatterelI. 1980). The phoM gene product acts as an activator that can parti ...
Recent retrotransposition events have not affected
... Expression state from eGenetics data (Kelso et al, Genome Research, 2003) ...
... Expression state from eGenetics data (Kelso et al, Genome Research, 2003) ...
Human, yeast and hybrid 3-phosphoglycerate kinase gene
... and is therefore underloaded. Based on these results and other "Northerns" (not shown), we conclude that the hPGK mRNA produced by unit e is about 70 percent of that produced by unit c, quantisation done by removal of bands and scintillation counting. Therefore in contrast to other heterologous gene ...
... and is therefore underloaded. Based on these results and other "Northerns" (not shown), we conclude that the hPGK mRNA produced by unit e is about 70 percent of that produced by unit c, quantisation done by removal of bands and scintillation counting. Therefore in contrast to other heterologous gene ...
and GvpD-mediated transcription regulation of the p
... 24–28 nt upstream of the transcription start site. An analysis of this sequence element in hyperthermophilic archaea indicates that it constitutes the TBP-binding site, especially when TBP is complexed with TFB (Kosa et al., 1997; Littlefield et al., 1999). The TFB-responsive element BRE, a purine-r ...
... 24–28 nt upstream of the transcription start site. An analysis of this sequence element in hyperthermophilic archaea indicates that it constitutes the TBP-binding site, especially when TBP is complexed with TFB (Kosa et al., 1997; Littlefield et al., 1999). The TFB-responsive element BRE, a purine-r ...
Mutations in SIN4 and RGR1 Cause Constitutive Expression of MAL
... Our previous work reported that the role of maltose permease in induction is the accumulation of intracellular maltose but the means of sensing the presence of intracellular maltose remain undetermined (Wang et al. 2002). It is possible that the MAL-activator itself is the maltose-binding sensor. Al ...
... Our previous work reported that the role of maltose permease in induction is the accumulation of intracellular maltose but the means of sensing the presence of intracellular maltose remain undetermined (Wang et al. 2002). It is possible that the MAL-activator itself is the maltose-binding sensor. Al ...
Plant LTR-retrotransposons and MITEs: control of
... 4 –8% of the genome, in large genomes like maize they can account for more than 50– 80% of their DNA content (Kumar and Bennetzen, 1999). The copy number of retrotransposons increases with their activity due to their replicative mechanism of transposition and has probably played a major role in plan ...
... 4 –8% of the genome, in large genomes like maize they can account for more than 50– 80% of their DNA content (Kumar and Bennetzen, 1999). The copy number of retrotransposons increases with their activity due to their replicative mechanism of transposition and has probably played a major role in plan ...
Human housekeeping genes are compact
... and the UTRs are less susceptible to change. It should be mentioned that intronless genes were included in our analysis after verifying that their inclusion or exclusion had no effect on the results. It also must be noted that the UTRs are not always fully sequenced, and thus their actual lengths mi ...
... and the UTRs are less susceptible to change. It should be mentioned that intronless genes were included in our analysis after verifying that their inclusion or exclusion had no effect on the results. It also must be noted that the UTRs are not always fully sequenced, and thus their actual lengths mi ...
General background text Pharmacogenetics - CYP3A4
... in question and the combination with environmental factors such as co-medication, diet and disease conditions. Variations can exist in a population for the DNA that encodes for a protein. Variations can result in alleles that encode for proteins with no or reduced activity. The simplest form of vari ...
... in question and the combination with environmental factors such as co-medication, diet and disease conditions. Variations can exist in a population for the DNA that encodes for a protein. Variations can result in alleles that encode for proteins with no or reduced activity. The simplest form of vari ...
The Birth- and- Death Evolution of Multigene Families Revisited
... families in question. For instance, gene families have been categorized separating those organized into gene clusters from those with members at dispersed locations across the chromosomes. Yet, a classification based on the underlying mechanism for the origin of the family members is, in many cases, ...
... families in question. For instance, gene families have been categorized separating those organized into gene clusters from those with members at dispersed locations across the chromosomes. Yet, a classification based on the underlying mechanism for the origin of the family members is, in many cases, ...
letter Widespread aneuploidy revealed by DNA microarray expression profiling
... rpb1∆187 data11 (Fig. 2b) and hhf2 depletion expression data12 (Fig. 2c). In addition, an expression profile of a pip2∆ oaf1∆ double mutant was recently determined by SAGE analysis13, and although the number of sequence tags for the mutant is small, there appears to be a chromosome-wide expression b ...
... rpb1∆187 data11 (Fig. 2b) and hhf2 depletion expression data12 (Fig. 2c). In addition, an expression profile of a pip2∆ oaf1∆ double mutant was recently determined by SAGE analysis13, and although the number of sequence tags for the mutant is small, there appears to be a chromosome-wide expression b ...
The microRNA, miR-29c, participates in muscle development
... differentiation and apoptosis[4–6]. The miR-29 family contains three members, miR-29a, miR-29b and miR29c[7], and they have similar expression patterns and biofunctions. MiR-29 can participate in many physiological and chemical processes. It has been reported that miR29a can inhibit apoptosis and pr ...
... differentiation and apoptosis[4–6]. The miR-29 family contains three members, miR-29a, miR-29b and miR29c[7], and they have similar expression patterns and biofunctions. MiR-29 can participate in many physiological and chemical processes. It has been reported that miR29a can inhibit apoptosis and pr ...
Gene overexpression reveals alternative
... increase in GCN4 mRNA translation, coupled with an extensive protein synthesis shut down. However, both phenomena are independent of Gcn2 function (Tzamarias et al., 1989). In addition, the assimilation of GCN4 mRNA translational derepression in vitro, does not require the Gcn2 kinase (Krupitza and ...
... increase in GCN4 mRNA translation, coupled with an extensive protein synthesis shut down. However, both phenomena are independent of Gcn2 function (Tzamarias et al., 1989). In addition, the assimilation of GCN4 mRNA translational derepression in vitro, does not require the Gcn2 kinase (Krupitza and ...
Expression of the Mitochondrial ATPase6 Gene and Tfam in Down
... (1996), the spindle exhibited abnormal tubulin placement and one or more chromosomes were displaced from the metaphase plate during the second meiotic division in 79% of oocytes in an older age group under investigation. In contrast, only 17% of the oocytes from a younger age group exhibited aneuplo ...
... (1996), the spindle exhibited abnormal tubulin placement and one or more chromosomes were displaced from the metaphase plate during the second meiotic division in 79% of oocytes in an older age group under investigation. In contrast, only 17% of the oocytes from a younger age group exhibited aneuplo ...
Constraint and divergence of global gene expression in
... eLife digest The way that the embryo of a mammal, such as a mouse or a human, develops from a fertilized egg is a complicated process that relies on controlling: which genes are active; when these genes activate; and for how long they are active. In broad terms, there are four ways that this control ...
... eLife digest The way that the embryo of a mammal, such as a mouse or a human, develops from a fertilized egg is a complicated process that relies on controlling: which genes are active; when these genes activate; and for how long they are active. In broad terms, there are four ways that this control ...
Ge´nie: literature-based gene prioritization at multi genomic scale
... literature, especially when they are from poorly studied organisms, the literature from equivalent (orthologous) genes in related organisms is usually taken into consideration under the assumption that proteins bearing high sequence similarity also share similar functions (4). However, the large num ...
... literature, especially when they are from poorly studied organisms, the literature from equivalent (orthologous) genes in related organisms is usually taken into consideration under the assumption that proteins bearing high sequence similarity also share similar functions (4). However, the large num ...
Sleep Spindles as Facilitators of Memory Formation and Learning
... involved in the consolidation of novel memories [23]. These studies show that spindles play a role in learning also in other species and that laboratory animals can be used to investigate the underlying mechanisms (see below). The correlative relationship of sleep spindles and memory task performanc ...
... involved in the consolidation of novel memories [23]. These studies show that spindles play a role in learning also in other species and that laboratory animals can be used to investigate the underlying mechanisms (see below). The correlative relationship of sleep spindles and memory task performanc ...
Mice homozygous for a targeted disruption of Hoxd-3
... parts are deleted, others are homeotically transformed ...
... parts are deleted, others are homeotically transformed ...
SGD sample annotations
... on a SDS-PAGE gel and the bands excised and identified by mass spectroscopy. These results are shown in Figures 1 and 2. Ahc1p was shown to be physically associated with the ADA complex by immunoprecipitation also and hence the authors conclude that Ahc1p is part of the ADA complex. This information ...
... on a SDS-PAGE gel and the bands excised and identified by mass spectroscopy. These results are shown in Figures 1 and 2. Ahc1p was shown to be physically associated with the ADA complex by immunoprecipitation also and hence the authors conclude that Ahc1p is part of the ADA complex. This information ...
Supplementary Methods Tables
... Data flow and organization. The TCGA data and analysis network involves leaders and teams working at multiple institutions and organizations in defined and coordinated roles, described briefly in the following overview. The Biospecimen Core Resources (BCRs) receive tissue samples and clinical metada ...
... Data flow and organization. The TCGA data and analysis network involves leaders and teams working at multiple institutions and organizations in defined and coordinated roles, described briefly in the following overview. The Biospecimen Core Resources (BCRs) receive tissue samples and clinical metada ...
Praktikum der Microarray-Datenanalyse
... • if H0 is true, no more than a fraction α of the replications will yield a p-value ≤ α • subject-sampling p-value: replications involve taking a new sample of subjects and measure same genes → a significant p-values gives confidence to find the same associations within a new sample of subjects • ge ...
... • if H0 is true, no more than a fraction α of the replications will yield a p-value ≤ α • subject-sampling p-value: replications involve taking a new sample of subjects and measure same genes → a significant p-values gives confidence to find the same associations within a new sample of subjects • ge ...
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... relies on this activity, which has proved to be the case from recent work by Ostendorff et al. (Ostendorff et al., 2002), in addition to its proposed role in recruiting the histone deacetylase complex (Bach et al., 1999). Thus, Rnf12/RLIM appears to be a negative regulator for LIM-HD/Ldb1 complexes. ...
... relies on this activity, which has proved to be the case from recent work by Ostendorff et al. (Ostendorff et al., 2002), in addition to its proposed role in recruiting the histone deacetylase complex (Bach et al., 1999). Thus, Rnf12/RLIM appears to be a negative regulator for LIM-HD/Ldb1 complexes. ...
DROSOPHILA: GENETICS MEETS BEHAVIOUR
... genetics is helping to clarify the nature of the genes and allelic variants that affect normal individual differences in behaviour, how they evolved and how they might differ from laboratory-generated mutants. Why might natural variants be useful tools for behavioural genetics analysis? Because they ...
... genetics is helping to clarify the nature of the genes and allelic variants that affect normal individual differences in behaviour, how they evolved and how they might differ from laboratory-generated mutants. Why might natural variants be useful tools for behavioural genetics analysis? Because they ...