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Impact of diet on adult hippocampal neurogenesis
... these new neurons start also to receive synaptic inputs from the cortex and are capable of firing action potentials [118]. Therefore, these newly generated neurons become physiologically mature and functionally integrated in the circuit. It is still not perfectly understood why neurogenesis is restr ...
... these new neurons start also to receive synaptic inputs from the cortex and are capable of firing action potentials [118]. Therefore, these newly generated neurons become physiologically mature and functionally integrated in the circuit. It is still not perfectly understood why neurogenesis is restr ...
Forward to the special issue on Hox/Tale transcription factors in
... skeleton. miRNAs produced at the ...
... skeleton. miRNAs produced at the ...
Nutrigenomics in the Patient Care Process: Figuring Out the Puzzle
... SNPs What’s Their Relevance? • Some SNPs change the gene’s “instruction manual” - encoding a protein with altered shape, activity, stability and/or abundance • Only certain SNPs are associated with difference in molecular function significant enough to effect clinical measurements or disease risk • ...
... SNPs What’s Their Relevance? • Some SNPs change the gene’s “instruction manual” - encoding a protein with altered shape, activity, stability and/or abundance • Only certain SNPs are associated with difference in molecular function significant enough to effect clinical measurements or disease risk • ...
Dopamine and adaptive memory - Shohamy Lab
... and novel and build memory representations well-suited to guide later choices. By integrating findings from both human and animal research, we argue for a framework in which dopamine helps create enriched mnemonic representations of the environment to support adaptive behavior. The hippocampus: Crea ...
... and novel and build memory representations well-suited to guide later choices. By integrating findings from both human and animal research, we argue for a framework in which dopamine helps create enriched mnemonic representations of the environment to support adaptive behavior. The hippocampus: Crea ...
Genetic or epigenetic difference causing discordance between
... valproate is known to be a histone deacetylase (HDAC) inhibitor. Histone acetylation is coupled with DNA methylation and plays a role in the epigenetic regulation of gene expression. If inhibition of HDAC by valproate is related to its efficacy, it may suggest that such epigenetic gene regulation ma ...
... valproate is known to be a histone deacetylase (HDAC) inhibitor. Histone acetylation is coupled with DNA methylation and plays a role in the epigenetic regulation of gene expression. If inhibition of HDAC by valproate is related to its efficacy, it may suggest that such epigenetic gene regulation ma ...
The Making of the Fittest: Natural Selection and Adaptation
... mating, occurrence of mutation, and, finally, selection. Selection is influenced by factors such as environmental change, predation, and disease. These actively influence the competitive advantage of specific traits present in a population. Point out that a population will almost always meet one or ...
... mating, occurrence of mutation, and, finally, selection. Selection is influenced by factors such as environmental change, predation, and disease. These actively influence the competitive advantage of specific traits present in a population. Point out that a population will almost always meet one or ...
Drug-specific Sites of Topoisomerase II DNA
... The addition of distamycin (25 @i)to Kc cells has been shown to stimulation by dh-EPI at the 5' end of the Hi gene and only weak stimulation between the H3 and H4 genes (sites 8a and 8b in Fig. 3). markedly increase VM-26-stimulated cleavage levels in SAR regions Weaker sites stimulated by dh-EPI we ...
... The addition of distamycin (25 @i)to Kc cells has been shown to stimulation by dh-EPI at the 5' end of the Hi gene and only weak stimulation between the H3 and H4 genes (sites 8a and 8b in Fig. 3). markedly increase VM-26-stimulated cleavage levels in SAR regions Weaker sites stimulated by dh-EPI we ...
The Making of the Fittest: Natural Selection and Adaptation
... mating, occurrence of mutation, and, finally, selection. Selection is influenced by factors such as environmental change, predation, and disease. These actively influence the competitive advantage of specific traits present in a population. Point out that a population will almost always meet one or ...
... mating, occurrence of mutation, and, finally, selection. Selection is influenced by factors such as environmental change, predation, and disease. These actively influence the competitive advantage of specific traits present in a population. Point out that a population will almost always meet one or ...
Chapter 16: Gene Regulation in Bacteria
... 4. Recognize how repressors and antisense RNAs are used in translational regulation. 5. Recognize how feedback inhibition is used in posttranslational regulation. 6. Know how riboswitches can regulate gene expression. 16.1 Overview of Transcriptional Regulation Overview Gene regulation can occur at ...
... 4. Recognize how repressors and antisense RNAs are used in translational regulation. 5. Recognize how feedback inhibition is used in posttranslational regulation. 6. Know how riboswitches can regulate gene expression. 16.1 Overview of Transcriptional Regulation Overview Gene regulation can occur at ...
GUEST COMMENTARY
... chromosomal location near tonB. Franklin, Dove, and Yanofsky (15) had shown that many mutations conferring resistance to phage T1 were tonB deletions, some of which extended into the trp operon on one side and/or att80 on the other. The fact ...
... chromosomal location near tonB. Franklin, Dove, and Yanofsky (15) had shown that many mutations conferring resistance to phage T1 were tonB deletions, some of which extended into the trp operon on one side and/or att80 on the other. The fact ...
The making of the Fittest: Natural Selection and Adaptation
... mating, occurrence of mutation, and, finally, selection. Selection is influenced by factors such as environmental change, predation, and disease. These actively influence the competitive advantage of specific traits present in a population. Point out that a population will almost always meet one or ...
... mating, occurrence of mutation, and, finally, selection. Selection is influenced by factors such as environmental change, predation, and disease. These actively influence the competitive advantage of specific traits present in a population. Point out that a population will almost always meet one or ...
Developmental regulation and individual differences of neuronal
... and genome organization, are critical intermediates for numerous genetic and environmental factors affecting neuronal functions in healthy and diseased brains (1). For example, there is increasing evidence that epigenetic alterations in the cerebral cortex and hippocampus play an important role in t ...
... and genome organization, are critical intermediates for numerous genetic and environmental factors affecting neuronal functions in healthy and diseased brains (1). For example, there is increasing evidence that epigenetic alterations in the cerebral cortex and hippocampus play an important role in t ...
Caspary T, Cleary MA, Perlman EJ, Zhang P, Elledge SJ, and Tilghman SM. Genes Dev. 1999 Dec 1;13(23):3115-24. Oppositely imprinted genes p57Kip2 and Igf2 interact in a mouse model for Beckwith-Wiedemann syndrome.
... cells, and large accumulations of red blood cells (Fig. 2B). A similar disorganization was seen at 16.5. and 17.5 d.p.c., suggesting that this effect occurs before the normal degeneration of the organ late in gestation. It is unclear whether red blood cells accumulate because the tubule networks thr ...
... cells, and large accumulations of red blood cells (Fig. 2B). A similar disorganization was seen at 16.5. and 17.5 d.p.c., suggesting that this effect occurs before the normal degeneration of the organ late in gestation. It is unclear whether red blood cells accumulate because the tubule networks thr ...
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... genes, one from each parent. This redundancy probably evolved by selection for a ‘backup’ copy of each gene, in case one copy is mutated. Genes subject to genomic imprinting (!100 in humans and mice [1]) forgo this safety-net because they inactivate either the maternal or paternal allele, causing at ...
... genes, one from each parent. This redundancy probably evolved by selection for a ‘backup’ copy of each gene, in case one copy is mutated. Genes subject to genomic imprinting (!100 in humans and mice [1]) forgo this safety-net because they inactivate either the maternal or paternal allele, causing at ...
Wk12-DeanApop
... promoter was used in luciferase-linked reporter genes (Fig. 2A) • This involved cutting out pieces from the promoter until it no longer worked... ...
... promoter was used in luciferase-linked reporter genes (Fig. 2A) • This involved cutting out pieces from the promoter until it no longer worked... ...
File - UCLA Neuroscience
... positioning in laminated structures in the brain. Genome-wide linkage studies show a connection between ASD and the 7q locus, where the reelin gene is located. ASD patients also show reduced levels of reelin protein and mRNA expression. Reelin function may be affected by organophosphate pesticides, ...
... positioning in laminated structures in the brain. Genome-wide linkage studies show a connection between ASD and the 7q locus, where the reelin gene is located. ASD patients also show reduced levels of reelin protein and mRNA expression. Reelin function may be affected by organophosphate pesticides, ...
Deep Insight Section Genomic Imprinting: Parental differentiation of the genome
... in total (Luedi PP et al., 2005.). In addition to identifying and validating the various imprinted genes, a major focus of current research in this field is to understand how and why some alleles "remember" their parental lineage long after pronuclear fusion in the zygote, while the majority of alle ...
... in total (Luedi PP et al., 2005.). In addition to identifying and validating the various imprinted genes, a major focus of current research in this field is to understand how and why some alleles "remember" their parental lineage long after pronuclear fusion in the zygote, while the majority of alle ...
ppt - Chair of Computational Biology
... The junctions were grouped according to the directionality of the reactions, as shown. Divergent junctions, which allow the flow of metabolites in two alternative directions, predominantly show a linear coregulation pattern, where one of the emanating reaction is correlated with the incoming reactio ...
... The junctions were grouped according to the directionality of the reactions, as shown. Divergent junctions, which allow the flow of metabolites in two alternative directions, predominantly show a linear coregulation pattern, where one of the emanating reaction is correlated with the incoming reactio ...
Loss And Gain Of Function Experiments Implicate TMEM18
... intake at 2 weeks (Fig 4I) and DEXA scanning at 6-weeks post-surgery showed a significant difference in both total and fat mass between the two groups of mice (Fig 4J). TMEM18 contains four, not three, transmembrane domains TMEM18 has been described to be a three transmembrane protein that localizes ...
... intake at 2 weeks (Fig 4I) and DEXA scanning at 6-weeks post-surgery showed a significant difference in both total and fat mass between the two groups of mice (Fig 4J). TMEM18 contains four, not three, transmembrane domains TMEM18 has been described to be a three transmembrane protein that localizes ...
Studies on Chlamydomonas Chloroplast Transformation: Foreign
... of nonphotosynthetic, acetate-requiring mutants of Chlamydomonas reinhardtii with genetic lesions in the chloroplast-encoded atpB, psbA, and rbcL genes by wild-type DNA sequences delivered on microprojectiles. DNA gel blot analysis of photosynthetically active transformants obtained from an atpB del ...
... of nonphotosynthetic, acetate-requiring mutants of Chlamydomonas reinhardtii with genetic lesions in the chloroplast-encoded atpB, psbA, and rbcL genes by wild-type DNA sequences delivered on microprojectiles. DNA gel blot analysis of photosynthetically active transformants obtained from an atpB del ...
Cholinergic Deafferentation of the Entorhinal Cortex in Rats
... Subsequent to the retrieval of the reinforcer from the sample cup, the rat and cup were removed from the platform, and the surface was cleaned with a 70% ethanol solution. The rat was placed in his home cage for the duration of the delay period (15, 30, 60, or 180 min) and returned to the center of ...
... Subsequent to the retrieval of the reinforcer from the sample cup, the rat and cup were removed from the platform, and the surface was cleaned with a 70% ethanol solution. The rat was placed in his home cage for the duration of the delay period (15, 30, 60, or 180 min) and returned to the center of ...
5 - digbio
... step 2: add to tree as along as no cycle is formed step 3: remove the edge from graph step 4: repeat steps 1-3 till all nodes are connected in tree. ...
... step 2: add to tree as along as no cycle is formed step 3: remove the edge from graph step 4: repeat steps 1-3 till all nodes are connected in tree. ...
Ribosome stalls at trp codons, allowing 2+3 pairing Transcription
... Enzymes acting in pathway to produce tryptophan. Gene order correlates with order of reactions in pathway. Premature termination of transcription when trp levels are high ...
... Enzymes acting in pathway to produce tryptophan. Gene order correlates with order of reactions in pathway. Premature termination of transcription when trp levels are high ...
Gene expression patterns in human placenta
... trophoblasts, interposed fibrinoid, and the endometrial components (stromal and fibroblast-like cells, as well as some macrophages, veins, and arteries). Genome-scale transcriptional profiling has been used to study many human diseases and physiological processes, as well as to characterize gene-exp ...
... trophoblasts, interposed fibrinoid, and the endometrial components (stromal and fibroblast-like cells, as well as some macrophages, veins, and arteries). Genome-scale transcriptional profiling has been used to study many human diseases and physiological processes, as well as to characterize gene-exp ...