Prof. Kamakaka`s Lecture 16 Notes
... also required positive regulation. That is, a factor was needed for specific activation of the operon. The specific activator was called CAP ( Catabolic activator protein) produced by the gene crp (not part of the lac operon). CAP forms a complex with cyclic AMP (cAMP). This complex is capable of ac ...
... also required positive regulation. That is, a factor was needed for specific activation of the operon. The specific activator was called CAP ( Catabolic activator protein) produced by the gene crp (not part of the lac operon). CAP forms a complex with cyclic AMP (cAMP). This complex is capable of ac ...
Deciphering the developmental program in the ascidian
... the overall GRN (Fig. 1). Living organisms tend to exclude wastefulness from their genomes. Consequently, a paradoxical phenomenon might emerge: genes that are more critical for development might show fewer abnormalities than less important genes when they are knocked out because of functional redun ...
... the overall GRN (Fig. 1). Living organisms tend to exclude wastefulness from their genomes. Consequently, a paradoxical phenomenon might emerge: genes that are more critical for development might show fewer abnormalities than less important genes when they are knocked out because of functional redun ...
Eur. J. Ophthalmol. 1... - digital
... magnification. All micrographs were digitalized, as previously described - Axonal Counting, Myelin sheaths and Axonal degeneration recording: The total number of normal/altered axons in the electron micrographs of similar magnification and study area from the three groups were counted. The number of ...
... magnification. All micrographs were digitalized, as previously described - Axonal Counting, Myelin sheaths and Axonal degeneration recording: The total number of normal/altered axons in the electron micrographs of similar magnification and study area from the three groups were counted. The number of ...
My First PowerPoint Presentation
... Block cocaine and NMDA antagonists (PCP, L-687,414) - induced hyperactivity Potentiate effects of Olanzapine on psychostimulant-induced hyperacitivity Brain activation pattern reminiscent of the antipsychotic drug Olanzapine ...
... Block cocaine and NMDA antagonists (PCP, L-687,414) - induced hyperactivity Potentiate effects of Olanzapine on psychostimulant-induced hyperacitivity Brain activation pattern reminiscent of the antipsychotic drug Olanzapine ...
Full Text - Harvard University
... There are two main concepts in Neo-Darwinian evolution theory: Genotype and Phenotype. Genotype refers to the all the genetic information that constitutes an organism. Phenotype refers to all the observable traits or characteristics of that organism. Considering gene expression as an observable trai ...
... There are two main concepts in Neo-Darwinian evolution theory: Genotype and Phenotype. Genotype refers to the all the genetic information that constitutes an organism. Phenotype refers to all the observable traits or characteristics of that organism. Considering gene expression as an observable trai ...
Marwa Yahia Ahmed_o
... masking coexisting IL-1 activity in tissue. The major biological role of extracellular sIL1Ra isoform is to compete with IL-1 agonists for binding to cell surface receptors, thus modulating their effect. Whereas, the intracellular IL-1Ra may be a storage form that is released upon necrotic cell deat ...
... masking coexisting IL-1 activity in tissue. The major biological role of extracellular sIL1Ra isoform is to compete with IL-1 agonists for binding to cell surface receptors, thus modulating their effect. Whereas, the intracellular IL-1Ra may be a storage form that is released upon necrotic cell deat ...
Strains to Theiler`s Virus Persistent Infection the Difference of
... Theiler’s virus causes a persistent infection with demyelination that is studied as a model for multiple sclerosis. Inbred strains of mice differ in their susceptibility to viral persistence due to both H-2 and non-H-2 genes. A locus with a major effect on persistence has been mapped on chromosome 1 ...
... Theiler’s virus causes a persistent infection with demyelination that is studied as a model for multiple sclerosis. Inbred strains of mice differ in their susceptibility to viral persistence due to both H-2 and non-H-2 genes. A locus with a major effect on persistence has been mapped on chromosome 1 ...
Interaction of a GATA factor with cis-acting elements involved in light
... We have previously identified a cis-acting element, named the XXIII box, that is essential for light-regulated expression of the nuclear gene GAPB, which encodes the B subunit of chloroplast glyceraldehyde-3-phosphate dehydrogenase from Arabidopsis thaliana. Examination of the sequences indicated tha ...
... We have previously identified a cis-acting element, named the XXIII box, that is essential for light-regulated expression of the nuclear gene GAPB, which encodes the B subunit of chloroplast glyceraldehyde-3-phosphate dehydrogenase from Arabidopsis thaliana. Examination of the sequences indicated tha ...
93134006蔡家妮 期中作業二
... comparative analysis of the nanH (VC1784) gene tree with the species gene tree, deduced from the housekeeping gene malate dehydrogenase (mdh), among V. cholerae and V. mimicus isolates. Both gene trees showed an overall congruence; on both gene trees V. cholerae O1 and O139 serogroup isolates cluste ...
... comparative analysis of the nanH (VC1784) gene tree with the species gene tree, deduced from the housekeeping gene malate dehydrogenase (mdh), among V. cholerae and V. mimicus isolates. Both gene trees showed an overall congruence; on both gene trees V. cholerae O1 and O139 serogroup isolates cluste ...
Growth medium composition-determined regulatory mechanisms
... Transcriptional activation from the pheBA and catBCA promoters is regulated by CatR and the catechol degradation pathway intermediate cis,cis-muconate. Here it is shown that physiological control mechanisms are superimposed on this regulatory system. Transcriptional activation from the pheBA and cat ...
... Transcriptional activation from the pheBA and catBCA promoters is regulated by CatR and the catechol degradation pathway intermediate cis,cis-muconate. Here it is shown that physiological control mechanisms are superimposed on this regulatory system. Transcriptional activation from the pheBA and cat ...
APPSWE Microinjected Mouse Model
... Abnormalities in synaptic properties are evident. For example, long-term potentiation of neurons in the CA1 and dentate gyrus regions of the hippocampus has been reported to be markedly impaired in older transgenic mice (15-17 months) but not young ones (2-8 months).2 This was correlated with Aβ acc ...
... Abnormalities in synaptic properties are evident. For example, long-term potentiation of neurons in the CA1 and dentate gyrus regions of the hippocampus has been reported to be markedly impaired in older transgenic mice (15-17 months) but not young ones (2-8 months).2 This was correlated with Aβ acc ...
Identification of chromosome intervals from 129 and C57BL/6 mouse
... developed an autoimmune phenotype. The humoral autoimmunity in this congenic strain was indistinguishable to that observed in a mouse carrying a deletion of the Apcs gene, located within the lupus-linked genomic region on distal chromosome 1 and considered as a candidate gene for murine SLE.6 Theref ...
... developed an autoimmune phenotype. The humoral autoimmunity in this congenic strain was indistinguishable to that observed in a mouse carrying a deletion of the Apcs gene, located within the lupus-linked genomic region on distal chromosome 1 and considered as a candidate gene for murine SLE.6 Theref ...
Imprinted gene expression in hybrids: perturbed
... The developmental establishment and maintenance of imprinting involve complex interactions between cis-regulatory elements and trans-acting factors, some of which are themselves subject to imprinting (Kelsey and Feil, 2013; Wolf, 2013). The transcription factor gene ZAC1 is imprinted in both mice an ...
... The developmental establishment and maintenance of imprinting involve complex interactions between cis-regulatory elements and trans-acting factors, some of which are themselves subject to imprinting (Kelsey and Feil, 2013; Wolf, 2013). The transcription factor gene ZAC1 is imprinted in both mice an ...
Model information sheet - EU
... enlarged lymphoid follicles containing multiple germinal centres. Later in life a second phase of lymphoproliferation occurs; this is characterised by extreme plasma cell hyperplasia in lymphoid tissue throughout the body (ILAR, 1989). An increased incidence of lymphoma has been reported (East, 1970 ...
... enlarged lymphoid follicles containing multiple germinal centres. Later in life a second phase of lymphoproliferation occurs; this is characterised by extreme plasma cell hyperplasia in lymphoid tissue throughout the body (ILAR, 1989). An increased incidence of lymphoma has been reported (East, 1970 ...
Cloning and Genetic Analysis of Six Pyrroloquinoline
... Under the conditions described in Methods, 80% of the cells of M . organophilum DSM 760 were killed by EMS. In preliminary experiments the mutagenized cells were used to inoculate separate small cultures, with the aim of isolating a single mutant strain from each culture, so as to obtain independent ...
... Under the conditions described in Methods, 80% of the cells of M . organophilum DSM 760 were killed by EMS. In preliminary experiments the mutagenized cells were used to inoculate separate small cultures, with the aim of isolating a single mutant strain from each culture, so as to obtain independent ...
Coupling of zygotic transcription to mitotic control at the Drosophila
... degradation are coupled through the transcription of specific microRNAs that promote maternal RNA deadenylation and clearance (Giraldez et al., 2006). A similar role for zygotically expressed miRNAs has been postulated for maternal RNA degradation during Drosophila MBT (Bushati et al., 2008). Howeve ...
... degradation are coupled through the transcription of specific microRNAs that promote maternal RNA deadenylation and clearance (Giraldez et al., 2006). A similar role for zygotically expressed miRNAs has been postulated for maternal RNA degradation during Drosophila MBT (Bushati et al., 2008). Howeve ...
Time-shift and inverse clustering of expression data finds new
... highlighted in the black cell. There is a time delay (time shift) in their relationship because the match score of 19 is not on the main diagonal of the matrix. Figure 1F is the corresponding matrix D for the profiles shown in Fig. 1C. The match score is S=20; and because the maximum value is from m ...
... highlighted in the black cell. There is a time delay (time shift) in their relationship because the match score of 19 is not on the main diagonal of the matrix. Figure 1F is the corresponding matrix D for the profiles shown in Fig. 1C. The match score is S=20; and because the maximum value is from m ...
Evolution of antifreeze glycoprotein gene from a trypsinogen gene in
... of special blood-borne antifreeze glycoproteins (AFGPs; ref. 6). Antifreeze proteins prevent freezing of the body fluids of teleosts, whose equilibrium freezing point (20.7 to 218C) is significantly higher than that of seawater (21.98C), by adsorbing to small ice crystals in the body and inhibiting ...
... of special blood-borne antifreeze glycoproteins (AFGPs; ref. 6). Antifreeze proteins prevent freezing of the body fluids of teleosts, whose equilibrium freezing point (20.7 to 218C) is significantly higher than that of seawater (21.98C), by adsorbing to small ice crystals in the body and inhibiting ...
(reversed and/or heterotaxic) phenotype in SWV mice
... experiment 3; one animal was homozygous for the upper (SWV) allele, presumably representing a recombinant between the iu and Igh-C loci (Fig. 2; Hanzlik et al., ’90). The incidence of the IV phenotype a s shown by reversal a t birth and the phenotype at autopsy is given in Table l. The incidence of ...
... experiment 3; one animal was homozygous for the upper (SWV) allele, presumably representing a recombinant between the iu and Igh-C loci (Fig. 2; Hanzlik et al., ’90). The incidence of the IV phenotype a s shown by reversal a t birth and the phenotype at autopsy is given in Table l. The incidence of ...
Sex Chromosome Dosage Effects On Gene Expression In
... reverse transcription polymerase chain reaction (qPCR) measures of expression for genes of interest identified in our core sample (Table S1, Material and Methods). To first verify our study design as a tool for probing SCD effects on gene expression, and to identify core SCD-sensitive genes, we scre ...
... reverse transcription polymerase chain reaction (qPCR) measures of expression for genes of interest identified in our core sample (Table S1, Material and Methods). To first verify our study design as a tool for probing SCD effects on gene expression, and to identify core SCD-sensitive genes, we scre ...
PDF
... reverse transcription polymerase chain reaction (qPCR) measures of expression for genes of interest identified in our core sample (Table S1, Material and Methods). To first verify our study design as a tool for probing SCD effects on gene expression, and to identify core SCD-sensitive genes, we scre ...
... reverse transcription polymerase chain reaction (qPCR) measures of expression for genes of interest identified in our core sample (Table S1, Material and Methods). To first verify our study design as a tool for probing SCD effects on gene expression, and to identify core SCD-sensitive genes, we scre ...
Involvement of HLS1 in Sugar and Auxin
... transition, leaf senescence and development of storage organs such as seeds or tubers (Bernier et al. 1993, Koch 1996, Jackson 1999, Smeekens 2000, Rolland et al. 2002, Borisjuk et al. 2004, Gibson 2005, Wingler et al. 2006). Studies carried out over the past 10 years have begun to reveal the molecu ...
... transition, leaf senescence and development of storage organs such as seeds or tubers (Bernier et al. 1993, Koch 1996, Jackson 1999, Smeekens 2000, Rolland et al. 2002, Borisjuk et al. 2004, Gibson 2005, Wingler et al. 2006). Studies carried out over the past 10 years have begun to reveal the molecu ...
Journal of Plant Physiology
... protein (AP2/EREBP) transcription factors have important functions in the transcriptional regulation of biological processes related to growth and development, as well as in responses to environmental stimuli (Riechmann and Meyerowitz, 1998; Gutterson and Reuber, 2004). The Arabidopsis genome encode ...
... protein (AP2/EREBP) transcription factors have important functions in the transcriptional regulation of biological processes related to growth and development, as well as in responses to environmental stimuli (Riechmann and Meyerowitz, 1998; Gutterson and Reuber, 2004). The Arabidopsis genome encode ...
Differential Gene Expression in the Gastrula of Xenopus Laevis
... Confirmed the presence of Differential Gastrula mRNA separate from Maternal mRNA Gradually disappear after Gastrula; Implication that it has little preceding stages. Some increase in concentration. ...
... Confirmed the presence of Differential Gastrula mRNA separate from Maternal mRNA Gradually disappear after Gastrula; Implication that it has little preceding stages. Some increase in concentration. ...
Creating conditional dual fluorescence labelled transgenic animals
... In addition to messenger RNA that encodes proteins, non-coding RNAs, including microRNA (miRNA) and long non-coding RNA (lncRNA) have been shown to be involved in gene regulation at post-transcriptional and translational levels. For example, microRNAs, about 22 nucleotide long, are among the largest ...
... In addition to messenger RNA that encodes proteins, non-coding RNAs, including microRNA (miRNA) and long non-coding RNA (lncRNA) have been shown to be involved in gene regulation at post-transcriptional and translational levels. For example, microRNAs, about 22 nucleotide long, are among the largest ...