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Genomic gains and losses influence expression levels of genes
... PMS2L8, PMS2L9), apoptosis (TAX1BP1, CASP2, CARD4), DNA replication (RIP60, SSBP1), and signal transduction (AKAP9, CARD4). Also HOXA3 and HOXA9 were significantly lower expressed in AML-MO7 than in all other subtypes. In inborn diseases as well as in several malignant diseases, a pathogenetic role ...
... PMS2L8, PMS2L9), apoptosis (TAX1BP1, CASP2, CARD4), DNA replication (RIP60, SSBP1), and signal transduction (AKAP9, CARD4). Also HOXA3 and HOXA9 were significantly lower expressed in AML-MO7 than in all other subtypes. In inborn diseases as well as in several malignant diseases, a pathogenetic role ...
Genome Biology - Institute for Applied Ecology
... and untranscribed [22]. In addition, histone H4 at lysine residue 16 is acetylated in a region surrounding the MHM locus in ZW females but not in ZZ males [23]. Other noncoding RNAs, such as XIST in mammals and roX genes in Drosophila, are implicated in the control of X chromosome dosage compensatio ...
... and untranscribed [22]. In addition, histone H4 at lysine residue 16 is acetylated in a region surrounding the MHM locus in ZW females but not in ZZ males [23]. Other noncoding RNAs, such as XIST in mammals and roX genes in Drosophila, are implicated in the control of X chromosome dosage compensatio ...
The Comparison of Transcriptomes Undergoing Waterlogging at the
... under waterlogging stress. It is interesting to note that 3.1% of differentially expressed transcripts encode products that are involved in pathways related to cell-wall loosening enzymes. An additional 6.7% of the differentially expressed transcripts were predicted to encode enzymes related to prot ...
... under waterlogging stress. It is interesting to note that 3.1% of differentially expressed transcripts encode products that are involved in pathways related to cell-wall loosening enzymes. An additional 6.7% of the differentially expressed transcripts were predicted to encode enzymes related to prot ...
gene_expression
... Partitioning is a special case of fuzzy clustering, where the weights are restricted to binary values Hierarchical clustering is also “fuzzy” in some sense ...
... Partitioning is a special case of fuzzy clustering, where the weights are restricted to binary values Hierarchical clustering is also “fuzzy” in some sense ...
- SciTech Connect
... of oskar and bicoid mRNAs, which is established during oogenesis.9,10 Mislocalization of either oskar or bicoid mRNA in the oocyte leads to defects in segment specification, such as defective heads in the embryo.9,10 These and other studies demonstrate that maternally supplied RNAs are required for ...
... of oskar and bicoid mRNAs, which is established during oogenesis.9,10 Mislocalization of either oskar or bicoid mRNA in the oocyte leads to defects in segment specification, such as defective heads in the embryo.9,10 These and other studies demonstrate that maternally supplied RNAs are required for ...
How Biologists Conceptualize Genes: An empirical study
... unit. This has led to definitions of the gene, which include the promoter and regulatory sequences that affect whether the gene will be transcribed. In a case like the famous lac operon in E. coli, these sites are immediately upstream of the site at which transcription is initiated and it is easy to ...
... unit. This has led to definitions of the gene, which include the promoter and regulatory sequences that affect whether the gene will be transcribed. In a case like the famous lac operon in E. coli, these sites are immediately upstream of the site at which transcription is initiated and it is easy to ...
Opposing Activities of DRM and MES
... expressed at very low levels and poised for reactivation. Such finetuning is particularly important for genes for which a relatively small degree of transcriptional variability may have a profound influence on cell identity or function. For example, transcription of Oct3/4, which is critical for self- ...
... expressed at very low levels and poised for reactivation. Such finetuning is particularly important for genes for which a relatively small degree of transcriptional variability may have a profound influence on cell identity or function. For example, transcription of Oct3/4, which is critical for self- ...
SUSCEPTIBILITY TO TRANSMITTED
... a single dominant gene. Conspicuously higher values were obtained only in an occasional small test, and can be explained by chance occurrence. These findings are in agreement with the hypothesis of dominance, since all hybrid combinations have a substantial proportion of susceptible individuals. The ...
... a single dominant gene. Conspicuously higher values were obtained only in an occasional small test, and can be explained by chance occurrence. These findings are in agreement with the hypothesis of dominance, since all hybrid combinations have a substantial proportion of susceptible individuals. The ...
Interacting Gene Clusters and the Evolution of the Vertebrate
... of gene clusters and hypothesized that gene clusters may consist of slowly evolving genes and that this alone might explain the higher conservation of the clusters. We compared the distribution of the evolutionary conservation of genes in clusters (i.e., the phylogenetic range over which they were d ...
... of gene clusters and hypothesized that gene clusters may consist of slowly evolving genes and that this alone might explain the higher conservation of the clusters. We compared the distribution of the evolutionary conservation of genes in clusters (i.e., the phylogenetic range over which they were d ...
The relationship between higher‑order chromatin structure and
... So where do open chromatin fibres originate? Support for the idea that regions of ‘open’ chromatin fibres correspond to transcriptionally active genes came from sedimentation analysis of the chicken β‑globin locus. When active, i.e. in erythrocytes, chromatin from this locus sediments more slowly th ...
... So where do open chromatin fibres originate? Support for the idea that regions of ‘open’ chromatin fibres correspond to transcriptionally active genes came from sedimentation analysis of the chicken β‑globin locus. When active, i.e. in erythrocytes, chromatin from this locus sediments more slowly th ...
The Arabidopsis NAC Transcription Factor VNI2
... that VNI2, which is highly expressed in senescing plant tissues, is also induced by environmental stress conditions, suggesting that it may be involved in modulation of senescence in response to environmental stresses. We therefore decided to examine the potential role of VNI2 in the functional rela ...
... that VNI2, which is highly expressed in senescing plant tissues, is also induced by environmental stress conditions, suggesting that it may be involved in modulation of senescence in response to environmental stresses. We therefore decided to examine the potential role of VNI2 in the functional rela ...
Nucleotide Sequence of the Osmoregulatory proU Operon of
... the Sall site at position 1810 for another 26 codons; consistent with this identification is the observation by my colleagues and myself in maxicell experiments that a plasmid (pHYD56 [20]) in which this Sall end has been ligated with the SalI site of pBR322 (so that the open reading frame terminate ...
... the Sall site at position 1810 for another 26 codons; consistent with this identification is the observation by my colleagues and myself in maxicell experiments that a plasmid (pHYD56 [20]) in which this Sall end has been ligated with the SalI site of pBR322 (so that the open reading frame terminate ...
Bonus, a Drosophila TIF1 homologue, is a chromatin
... Several proteins have been identified that either interact with or modify HP1 (GREWAL and MOAZED 2003). One of these families of proteins is the TIF1 family. The TIF1 family of proteins, TIF1α (LE DOUARIN et al. 1995), TIF1β [also called KAP-1 (FRIEDMAN et al. 1996) or KRIP-1 (KIM et al. 1996)], an ...
... Several proteins have been identified that either interact with or modify HP1 (GREWAL and MOAZED 2003). One of these families of proteins is the TIF1 family. The TIF1 family of proteins, TIF1α (LE DOUARIN et al. 1995), TIF1β [also called KAP-1 (FRIEDMAN et al. 1996) or KRIP-1 (KIM et al. 1996)], an ...
Genes@ Work: an efficient algorithm for pattern discovery and
... we will explicitly handle the continuous nature of the gene expression data. Our definition of pattern can be interpreted as a cluster of samples over a subset of genes, an idea that has been referred to in the recent literature as biclustering. Recent biclustering work includes Cheng and Church (20 ...
... we will explicitly handle the continuous nature of the gene expression data. Our definition of pattern can be interpreted as a cluster of samples over a subset of genes, an idea that has been referred to in the recent literature as biclustering. Recent biclustering work includes Cheng and Church (20 ...
Neural tube defects and abnormal brain development in F52
... mice by the gene targeting technique. These mutant mice manifest severe neural tube defects that are not associated with other complex malformations, a phenotype reminiscent of common human neural tube defects. The neural tube defects observed include both exencephaly and spina bifida, and the pheno ...
... mice by the gene targeting technique. These mutant mice manifest severe neural tube defects that are not associated with other complex malformations, a phenotype reminiscent of common human neural tube defects. The neural tube defects observed include both exencephaly and spina bifida, and the pheno ...
Module 1: Introduction
... with your list (hopefully part of experiment design! ) – Summarize biological processes or other aspects of gene function – Controller for a process (TF) ...
... with your list (hopefully part of experiment design! ) – Summarize biological processes or other aspects of gene function – Controller for a process (TF) ...
DRACULA2 is a dynamic nucleoporin with a role in
... Nonetheless, transgenic seedlings with a mild phenotype had longer hypocotyls than Ws-2 under W; importantly, in these lines the hypocotyl response to W+FR was attenuated compared with Ws-2 (Fig. 1E, Fig. S3C). Together, these results indicated that At1g10390 is the causal gene for the phenotype of ...
... Nonetheless, transgenic seedlings with a mild phenotype had longer hypocotyls than Ws-2 under W; importantly, in these lines the hypocotyl response to W+FR was attenuated compared with Ws-2 (Fig. 1E, Fig. S3C). Together, these results indicated that At1g10390 is the causal gene for the phenotype of ...
Diversity of DNA methyltransferases that recognize asymmetric
... Multiple lines of evidence suggest that some DNA MTases function as dimers. Further, functional analysis of many restriction-modification systems showed the presence of more than one or fused MTase genes. It was proposed that presence of two MTases responsible for the recognition and methylation of ...
... Multiple lines of evidence suggest that some DNA MTases function as dimers. Further, functional analysis of many restriction-modification systems showed the presence of more than one or fused MTase genes. It was proposed that presence of two MTases responsible for the recognition and methylation of ...
channel 1 gene dosage
... wild-type, and this causes hyperexcitability, the salient feature of the disease myotonia. Potassium conductance (GK) values in myotonic mouse muscle fibres are lowered by about 60 % compared with wild-type. The defective ClCadr allele causes loss of the 4-5 kb ClC-1 mRNA. Mice heterozygous for the ...
... wild-type, and this causes hyperexcitability, the salient feature of the disease myotonia. Potassium conductance (GK) values in myotonic mouse muscle fibres are lowered by about 60 % compared with wild-type. The defective ClCadr allele causes loss of the 4-5 kb ClC-1 mRNA. Mice heterozygous for the ...
Lesson Plan, GeneChip® Microarrays: Teacher`s Guide
... module teaching guides, however, the general directions found in the student module are not repeated here. Rather than repeat all the student handouts with teacher directions added to it, the teacher directions provided here are completely separate. You should have a copy of the student directions a ...
... module teaching guides, however, the general directions found in the student module are not repeated here. Rather than repeat all the student handouts with teacher directions added to it, the teacher directions provided here are completely separate. You should have a copy of the student directions a ...
Genomic surveys and expression analysis of bZIP gene family in
... and oligo (dT) used as the primers to synthesize the first and second-strand cDNA. The cDNA was digested by two types of endonuclease NlaIII or DpnII, acquiring 17 bp tags with different adaptors of both ends to generate a tag library. After 15 cycles of linear PCR amplification, 105 bp fragments we ...
... and oligo (dT) used as the primers to synthesize the first and second-strand cDNA. The cDNA was digested by two types of endonuclease NlaIII or DpnII, acquiring 17 bp tags with different adaptors of both ends to generate a tag library. After 15 cycles of linear PCR amplification, 105 bp fragments we ...
First report of a tetracycline-inducible gene
... et al., 2005), conditional expression of toxin genes (Carroll et al., 2007), plasmid loss through inducible counterselection (Bae & Schneewind, 2006), titration of gene expression in the host cells (Corrigan et al., 2007), and antisense-mediated silencing of essential genes (Blokpoel et al., 2005). ...
... et al., 2005), conditional expression of toxin genes (Carroll et al., 2007), plasmid loss through inducible counterselection (Bae & Schneewind, 2006), titration of gene expression in the host cells (Corrigan et al., 2007), and antisense-mediated silencing of essential genes (Blokpoel et al., 2005). ...
... development 24 and 48 h post inoculation (Fig. 4A). PL secretion during the colonization of watermelon seedling stems by Cm-PL-3 and Cm-PL-10 was detected 48 h post inoculation, for Cg-14 and L-2.5 only after 120 h (Fig. 4B). Inoculation of watermelon seedlings with Cm-PL-10 and Cm-PL-3 caused dampi ...
A tandem repeat in decay accelerating factor 1 induced autoimmunity
... 15], prostaglandin PGE2 [16], and tissue specific factors [17]. Although there is evidence that DAF mRNA stability can be affected by tissue specific factors [17] and inflammation [18], most studies suggest that expression is primarily modulated at transcription [15–17, 19, 20]. The human DAF promot ...
... 15], prostaglandin PGE2 [16], and tissue specific factors [17]. Although there is evidence that DAF mRNA stability can be affected by tissue specific factors [17] and inflammation [18], most studies suggest that expression is primarily modulated at transcription [15–17, 19, 20]. The human DAF promot ...
Fulltext PDF - Indian Academy of Sciences
... higher temperatures, but often weeks later. There is, therefore, a clear temporal separation between the perception of cold temperature and the switch from vegetative to reproductive growth. Somehow the shoot apical meristem manages to “remember” the lessons that it learned in its cold underground c ...
... higher temperatures, but often weeks later. There is, therefore, a clear temporal separation between the perception of cold temperature and the switch from vegetative to reproductive growth. Somehow the shoot apical meristem manages to “remember” the lessons that it learned in its cold underground c ...