Multiple routes to memory: Distinct medial
... contextual recollection. Given the centrality of this issue for understanding the functional architecture of MTL, the present study used event-related functional MRI (fMRI) during episodic encoding to test whether perirhinal cortex, parahippocampal cortex, and hippocampus support distinct forms of l ...
... contextual recollection. Given the centrality of this issue for understanding the functional architecture of MTL, the present study used event-related functional MRI (fMRI) during episodic encoding to test whether perirhinal cortex, parahippocampal cortex, and hippocampus support distinct forms of l ...
Pseudogenes as regulators of biological function
... genes or pseudogenes) particularly challenging. Several pseudogenes exhibit tissue-specific patterns of transcription, with a particular prevalence for testis-specific expression [5,22]. Pseudogenes can also exhibit patterns of expression that are distinct from the parent coding genes from which the ...
... genes or pseudogenes) particularly challenging. Several pseudogenes exhibit tissue-specific patterns of transcription, with a particular prevalence for testis-specific expression [5,22]. Pseudogenes can also exhibit patterns of expression that are distinct from the parent coding genes from which the ...
LECTURE 13: EPIGENETICS – IMPRINTING Reading: Ch. 18, p
... putting either two female pronuclei or two male pronuclei into mouse eggs and then transferring the eggs into a foster mother. Control embryos derived from fusion of a maternally-derived pronucleus and a paternally-derived pronucleus developed normally, but embryos from the fusion of two maternally- ...
... putting either two female pronuclei or two male pronuclei into mouse eggs and then transferring the eggs into a foster mother. Control embryos derived from fusion of a maternally-derived pronucleus and a paternally-derived pronucleus developed normally, but embryos from the fusion of two maternally- ...
Inflorescence Meristem Identity in Rice Is Specified
... of inflorescence development studied here except that a low level of MADS5 expression was observed in the spikelet initiation stage (R4) (Figure 2B). Inflorescence Development Was Severely Perturbed in the MADS Quadruple Knockdown Plants To understand the role of PAP2 and the three AP1/FUL-like genes ...
... of inflorescence development studied here except that a low level of MADS5 expression was observed in the spikelet initiation stage (R4) (Figure 2B). Inflorescence Development Was Severely Perturbed in the MADS Quadruple Knockdown Plants To understand the role of PAP2 and the three AP1/FUL-like genes ...
Transcription regulation of the Escherichia coli pcnB gene coding for
... rapidly changing environmental conditions (SzalewskaPalasz et al. 2007b). There are two major eVectors of the stringent response. The Wrst one is a couple of two speciWc nucleotides, guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), collectively called (p)ppGpp and rapidly prod ...
... rapidly changing environmental conditions (SzalewskaPalasz et al. 2007b). There are two major eVectors of the stringent response. The Wrst one is a couple of two speciWc nucleotides, guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), collectively called (p)ppGpp and rapidly prod ...
14. Development and Plasticity
... To find the general principles of brain development is one of the major scientific quests in neuroscience Not all characteristics of the brain can be specified by a ...
... To find the general principles of brain development is one of the major scientific quests in neuroscience Not all characteristics of the brain can be specified by a ...
New Construct Approaches for Efficient Gene Silencing in Plants
... transcriptional terminator. Here, we show that this regulatory element becomes obsolete when gene fragments are positioned between two oppositely oriented and functionally active promoters. The resulting convergent transcription triggers gene silencing that is at least as effective as unidirectional ...
... transcriptional terminator. Here, we show that this regulatory element becomes obsolete when gene fragments are positioned between two oppositely oriented and functionally active promoters. The resulting convergent transcription triggers gene silencing that is at least as effective as unidirectional ...
14. Development and Plasticity
... To find the general principles of brain development is one of the major scientific quests in neuroscience Not all characteristics of the brain can be specified by a ...
... To find the general principles of brain development is one of the major scientific quests in neuroscience Not all characteristics of the brain can be specified by a ...
Gene Section USF1 (upstream transcription factor 1) Atlas of Genetics and Cytogenetics
... complex factors, coactivator and corepressor proteins (Corre and Galibert, 2005; Huang et al., 2007; Corre et al., 2009; Wong et al., 2009). In addition, USF1 interacts with other transcription factors to achieve cooperative transcriptional activation of individual genes (Corre and Galibert, 2005). ...
... complex factors, coactivator and corepressor proteins (Corre and Galibert, 2005; Huang et al., 2007; Corre et al., 2009; Wong et al., 2009). In addition, USF1 interacts with other transcription factors to achieve cooperative transcriptional activation of individual genes (Corre and Galibert, 2005). ...
Synaptogenesis in the human cortex occurs between - UvA-DARE
... reveals a paradox; as experiences cause more pruning and at the same time a better network how it is possible then, that EE results in more synapses, which also has a positive effect on the organism‟s behavior? At this moment it is not yet clear whether pruning actually occurs in CA1. The variety o ...
... reveals a paradox; as experiences cause more pruning and at the same time a better network how it is possible then, that EE results in more synapses, which also has a positive effect on the organism‟s behavior? At this moment it is not yet clear whether pruning actually occurs in CA1. The variety o ...
AtREM1, a Member of a New Family of B3 Domain
... In spite of the important role played by the genetic analysis in the identification of key genes in different biological processes, the results of current Arabidopsis genome sequencing projects show that only 8% of the gene sequences identified have been experimentally characterized to date (Lin et ...
... In spite of the important role played by the genetic analysis in the identification of key genes in different biological processes, the results of current Arabidopsis genome sequencing projects show that only 8% of the gene sequences identified have been experimentally characterized to date (Lin et ...
Hypotonic infants and the Prader-Willi Syndrome
... and 12 months of age with idiopathic hypotonia and detected 29 PWS cases (45%). Those authors emphasize that although this frequency is probably overestimated, due to an investigation bias, the methylation test should be performed in this group of patients, considering that it is non-invasive and ex ...
... and 12 months of age with idiopathic hypotonia and detected 29 PWS cases (45%). Those authors emphasize that although this frequency is probably overestimated, due to an investigation bias, the methylation test should be performed in this group of patients, considering that it is non-invasive and ex ...
Peroxisome Proliferator-Activated Receptor
... knockout mice.1 This is in marked contrast to the response seen in wild-type mice, in which exposure to clofibrate or Wy-14,643 causes increases in the number, size, and staining intensities of peroxisomes, as well as conspicuous swelling of mitochondria. A unique observation in hepatocytes of PPARα ...
... knockout mice.1 This is in marked contrast to the response seen in wild-type mice, in which exposure to clofibrate or Wy-14,643 causes increases in the number, size, and staining intensities of peroxisomes, as well as conspicuous swelling of mitochondria. A unique observation in hepatocytes of PPARα ...
The ARG9 Gene Encodes the Plastid-Resident N
... the dark. Cosegregation of the slow-growth phenotype with the Arg⫹ trait was observed, suggesting that insertion of the ARG9 gene interrupts a gene controlling respiration. However, neither mutant was deficient for complex I activity, as determined by enzymatic measurement or in-gel staining (data n ...
... the dark. Cosegregation of the slow-growth phenotype with the Arg⫹ trait was observed, suggesting that insertion of the ARG9 gene interrupts a gene controlling respiration. However, neither mutant was deficient for complex I activity, as determined by enzymatic measurement or in-gel staining (data n ...
Functional Annotation of Regulatory Pathways
... and a set of functional attributes VF, let 2VG and 2VF denote the power set of VG and VF, respectively. Then, functional annotation AðVG ; VF Þ ¼ fF ; Gg defines mapping F : VG ! 2VF and G : VF ! 2VG , such that Tj 2 F ðgi Þ if and only if gi 2 GðTj Þ, for any gi 2 VG and Tj 2 VF . The frequency of ...
... and a set of functional attributes VF, let 2VG and 2VF denote the power set of VG and VF, respectively. Then, functional annotation AðVG ; VF Þ ¼ fF ; Gg defines mapping F : VG ! 2VF and G : VF ! 2VG , such that Tj 2 F ðgi Þ if and only if gi 2 GðTj Þ, for any gi 2 VG and Tj 2 VF . The frequency of ...
Neuromodulation and cortical function: BEHAVIOURAL BRAIN
... cortical structures (along intrinsic and association fibers) is mediated by glutamatergic synaptic transmission. The glutamatergic neurons mediating this interaction between cortical regions are commonly pyramidal cells which display the property of neuronal adaptation. That is, they decrease in fir ...
... cortical structures (along intrinsic and association fibers) is mediated by glutamatergic synaptic transmission. The glutamatergic neurons mediating this interaction between cortical regions are commonly pyramidal cells which display the property of neuronal adaptation. That is, they decrease in fir ...
Brief neonatal maternal separation alters extinction of conditioned
... (e.g., Meerlo et al., 1999; but see Kosten et al., 2005). However, to our knowledge, the effects of maternal separation on learning and unlearning of conditioned fear and the corticolimbic structures mediating these behaviors have not been assessed. The neural substrates for acquisition of condition ...
... (e.g., Meerlo et al., 1999; but see Kosten et al., 2005). However, to our knowledge, the effects of maternal separation on learning and unlearning of conditioned fear and the corticolimbic structures mediating these behaviors have not been assessed. The neural substrates for acquisition of condition ...
The UCSC Known Genes
... Browser, at the UCSC web site. It also has extensive cross-references to other databases like GenBank/NCBI, Swiss-Prot/TrEMBL, KEGG, BioCyc, and many others. protein IDs and GenBank mRNA IDs is created from this UniProt data. The existing GenBank mRNA sequences are aligned with their corresponding p ...
... Browser, at the UCSC web site. It also has extensive cross-references to other databases like GenBank/NCBI, Swiss-Prot/TrEMBL, KEGG, BioCyc, and many others. protein IDs and GenBank mRNA IDs is created from this UniProt data. The existing GenBank mRNA sequences are aligned with their corresponding p ...
Eukaryotic Genes and Genomes II
... In the last lecture we considered the structure of genes in eukaryotic organisms and went on to figure out a way to identify S. cerevisiae genes that are transcriptionally regulated in response to a change in environment. The ability to regulate gene expression in response to environmental cues is a ...
... In the last lecture we considered the structure of genes in eukaryotic organisms and went on to figure out a way to identify S. cerevisiae genes that are transcriptionally regulated in response to a change in environment. The ability to regulate gene expression in response to environmental cues is a ...
Long-term potentiation in the anterior cingulate cortex and chronic
... cyclases (ACs), mainly AC1 and Ca2þ/CaM-dependent protein kinases. The trafficking of postsynaptic GluA1 containing AMPA receptor contributes to enhanced synaptic responses. An NMDA receptor independent form of LTP can be also induced. Activation of L-type voltage-gated calcium channels (L-VGCCs) is ...
... cyclases (ACs), mainly AC1 and Ca2þ/CaM-dependent protein kinases. The trafficking of postsynaptic GluA1 containing AMPA receptor contributes to enhanced synaptic responses. An NMDA receptor independent form of LTP can be also induced. Activation of L-type voltage-gated calcium channels (L-VGCCs) is ...
Dual-Tagging Gene Trap of Novel Genes in Drosophila
... functional information on nearby genes, although they are quite useful in monitoring the enhancer activity near the vector insertion site. In many cases, this expression pattern resembles that of the transcript of an intrinsic gene. The gene, however, may lie over tens of kilobases away from the ins ...
... functional information on nearby genes, although they are quite useful in monitoring the enhancer activity near the vector insertion site. In many cases, this expression pattern resembles that of the transcript of an intrinsic gene. The gene, however, may lie over tens of kilobases away from the ins ...
genes. Numbers of 6-10 copies per genome have
... The SSU genes and flanking regions in TSSU3-2 and TSSU3-8 were sequenced. Using sequences of other SSU genes, the leader peptide, mature coding regions and introns were located. In Figure 2, the sequence of these two genes is shown and compared to that of a previously sequenced tobacco SSU gene, NtS ...
... The SSU genes and flanking regions in TSSU3-2 and TSSU3-8 were sequenced. Using sequences of other SSU genes, the leader peptide, mature coding regions and introns were located. In Figure 2, the sequence of these two genes is shown and compared to that of a previously sequenced tobacco SSU gene, NtS ...
Tutorial - Ensembl
... An Ensembl gene may have multiple transcripts reflecting alternative splicing, in this case the EPO gene only shows one transcript in Ensembl. ...
... An Ensembl gene may have multiple transcripts reflecting alternative splicing, in this case the EPO gene only shows one transcript in Ensembl. ...
SNaPshot® Multiplex System for SNP genotyping
... Capillary electrophoretic analysis of methylation status in CpGrich regions by single-base extension of primers modified with N6-methoxy-2,6-diaminopurine. ...
... Capillary electrophoretic analysis of methylation status in CpGrich regions by single-base extension of primers modified with N6-methoxy-2,6-diaminopurine. ...