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Germ-line modification
Germ-line modification

... (2) None of the key terms are defined. What constitutes ‘identity’, ‘essential’ or ‘predetermined’ characteristics?  Does modification of the mtDNA alter the identity of the person born? ...
Hydrogen bond geometry in DNA–minor groove
Hydrogen bond geometry in DNA–minor groove

... (1). Different experimental and theoretical analyses have brought a large amount of information about sequence specificity, binding energies and stability of the several DNA–drug complexes (2–15). From the very beginning it was postulated that minor groove binding drugs as netropsin could recognize ...
Problem Sets - MIT Biology
Problem Sets - MIT Biology

... (g) List all of the above six crosses (parts (a) – (f)) that are proper complementation tests which clearly reveal whether two mutations are in the same gene or different genes. Part e) is a proper complementation test that clearly shows that wild-type alleles of A and B will rescue the mutant pheno ...
Flexibility of centromere and kinetochore structures
Flexibility of centromere and kinetochore structures

... cancers such as non-Hodgkin’s lymphoma [34], acute myeloid leukemia [35], and liposarcomas [36]. Neocentromeres map to at least 21 different human chromosomes, including X and Y, although they are particularly common on specific chromosome domains including 3q, 13q and 15q [32,37]. Little is known a ...
Article Mitochondrial DNA turnover occurs during preimplantation
Article Mitochondrial DNA turnover occurs during preimplantation

... fidelity of mtDNA synthesis with an associated reduction in the ...
`Candidatus Phytoplasma mali`, `Candidatus Phytoplasma pyri` and
`Candidatus Phytoplasma mali`, `Candidatus Phytoplasma pyri` and

... coherent, genus-level taxon. In the monophyletic phytoplasma clade, groups and subgroups have been delineated, many of which are being considered as putative species under the provisional status ‘Candidatus’ (Seemüller et al., 2002) for incompletely described prokaryotes, according to Murray & Stac ...
Genome-wide analysis of the distribution of AP2/ERF transcription
Genome-wide analysis of the distribution of AP2/ERF transcription

... Background: Cabbage (Brassica oleracea) is one of the most important leaf vegetables grown worldwide. The entire cabbage genome sequence and more than fifty thousand proteins have been obtained to date. However a high degree of sequence similarity and conserved genome structure remain between cabbag ...
Rh phenotype prediction by DNA typing and its
Rh phenotype prediction by DNA typing and its

... 1997). No consensus has yet been achieved as to which polymorphism may be most reliable for testing of any given population. RH and particularly RHD DNA typing is much confounded by the presence of two highly homologous genes, RHCE and RHD, and the complex polymorphisms between both genes. In contra ...
Questions & Answer keys Test 2 Genetic engg.
Questions & Answer keys Test 2 Genetic engg.

... Forensically, the DNA from a single hair, sperm or drop of blood can be used to identify by the analysis of: Select one: a. Short tandem repeats b. ESTs 16 of 24 ...
Disintegrin, hemorrhagic, and proteolytic activities of Mohave
Disintegrin, hemorrhagic, and proteolytic activities of Mohave

... disintegrins and Mojave toxin. All venom samples were analyzed for the presence of hemorrhagic, proteolytic and disintegrin activities. The venoms were each chromatographed by reverse phase and their fractions tested for disintegrin activity. All specimens containing Mojave toxin were the most toxic ...
The XTH Family of Enzymes Involved in Xyloglucan
The XTH Family of Enzymes Involved in Xyloglucan

... two pairs of solitary XTH genes have been identified as having been duplicated, possibly by transposition: At-XTH17 and AtXTH18 share almost identical sequences in their promoter regions, while At-XTH19 and At-XTH20 are identified as duplicates by phylogenetic analysis (Fig. 2B). The Arabidopsis XTH ...
htp Pseudomonas aeruginosa AMANDA SWANEPOEL
htp Pseudomonas aeruginosa AMANDA SWANEPOEL

... In the vast majority of ecological niches, P. aeruginosa can grow in association with surfaces, which leads to the formation of biofilms (Zobell, 1943; Costerton et al., 1995). Biofilms have been defined as structured communities of bacterial cells that are enclosed in a self-produced polymeric matr ...
Introduction to GO Annotation
Introduction to GO Annotation

... Sample text from PMID: 12374299 In this study, we report the isolation and molecular characterization of the B. napus PERK1 cDNA, that is predicted to encode a novel receptor-like kinase. We have shown that like other plant RLKs, the kinase domain of PERK1 has serine/threonine kinase activity, In ad ...
Inheritance of White Colour in Alpacas
Inheritance of White Colour in Alpacas

... Figure 3.17: The relative amount of total melanin present in different coloured alpaca fibres. .......................... 23  Figure 3.18: The relative proportion of type of melanin present in alpaca fibre of different colours. ................. 24  Figure 3.19: Comparison of total melanin content w ...
Chapter 4
Chapter 4

... The Human Genome Variation Society publishes nomenclature guidelines [den Dunnen et al., 2000] for unambiguous sequence variant descriptions used in clinical reports, literature and genetic databases. To check and interpret these descriptions the Mutalyzer program suite [Wildeman et al., 2008] has b ...
The universal reagent for genome tailoring
The universal reagent for genome tailoring

... which then allows the functioning of the targeted allele, provided nothing but the alteration embedded in the homology arm was introduced. Here again the loxPflanked selectable marker placed into a noncoding region (Fig. 3A) provides the solution (Nagy et al., 1998; Reichardt et al., 1998; Wang et a ...
Glioma heterogeneity and the LAT-1
Glioma heterogeneity and the LAT-1

... To date, glioblastoma subject to the most extensive genomic profiling of any cancer (Dunn, et al Genes Dev. 2012 26: 756-784) The Cancer Genome Atlas Research Network (Parsons et al. 2008) and other studies have enabled us to systematically and comprehensively define the genomic landscape of gliobla ...
Can Environmentally Induced Epigenetic Changes be Trans
Can Environmentally Induced Epigenetic Changes be Trans

GENETICS – BIO 300
GENETICS – BIO 300

... working with microorganisms ...
RT2 Profiler PCR Arrays: Pathway-focused gene
RT2 Profiler PCR Arrays: Pathway-focused gene

... JJ Performance: ...
Control of Lysogenization by Phage P22. II. Mutations (clyA) in the c1 Gene that Cause Increased Lysogenization
Control of Lysogenization by Phage P22. II. Mutations (clyA) in the c1 Gene that Cause Increased Lysogenization

... & Kaiser (1971) and Echols & Green (1971) proposed that the h ~11 and cl11 gene products are needed to activate transcription from a promoter, p,, (defined by cy mutations), in order to allow high-level transcription of the c1 gene during the early stages of h infection. Tokuno & Gough (1976) later ...
Are Incomplete Denitrification Pathways a Common Trait in Thermus
Are Incomplete Denitrification Pathways a Common Trait in Thermus

... 60 °C. The primary focus of this study was to investigate the denitrification pathways of Thermus (Bacteria) isolates from geothermal springs from Tengchong, China. This study tested the hypothesis that incomplete denitrification is a common characteristic of the genus Thermus, regardless of geograp ...
Leuconostoc miyukkimchii sp. nov., isolated from brown algae
Leuconostoc miyukkimchii sp. nov., isolated from brown algae

... that strain M2T was most closely related to Leuconostoc inhae IH003T, Leuconostoc kimchii IH25T, Leuconostoc gasicomitatum LMG 18811T, Leuconostoc gelidum DSM 5578T, Leuconostoc palmae TMW2.694T and Leuconostoc holzapfelii BFE 7000T with sequence similarities of 98.9 %, 98.8 %, 98.8 %, 98.7 %, 98.5 ...
what is alignment? - UWI St. Augustine
what is alignment? - UWI St. Augustine

1 Introduction - Wiley-VCH
1 Introduction - Wiley-VCH

... 1.5.1.1 Proteins that Interact with Single Stranded RNAs In many organisms, proteins with RNA binding activity are very abundant. The most common structural family or protein motif that binds single stranded RNA is the RNA recognition motif (RRM). In human, for example, this motif is present in abou ...
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Helitron (biology)

A helitron is a transposon found in eukaryotes that is thought to replicate by a so-called ""rolling-circle"" mechanism. This category of transposons was discovered by Vladimir Kapitonov and Jerzy Jurka in 2001. The rolling-circle process begins with a break being made at the terminus of a single strand of the helitron DNA. Transposase then sits at this break and at another break where the helitron targets as a migration site. The strand is then displaced from its original location at the site of the break and attached to the target break, forming a circlular heteroduplex. This heteroduplex is then resolved into a flat piece of DNA via replication. During the rolling-circle process, DNA can be replicated beyond the initial helitron sequence, resulting in the flanking regions of DNA being ""captured"" by the helitron as it moves to a new location.
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