1 Supplemental Table 1. FACS-isolated, SSEA-4
... partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias. -induces cartilage and bone formation, -based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. -the protein ...
... partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias. -induces cartilage and bone formation, -based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. -the protein ...
File - interACT - American College of Toxicology
... Zhejiang University in Hangzhou, China, and received her Ph.D. Degree with honors in University of Kansas Medical Center. Julia currently is an Assistant Professor in Toxicology in the Department of Environmental and Occupational Health Sciences. She is a recipient of the Sheldon D. Murphy Endowed C ...
... Zhejiang University in Hangzhou, China, and received her Ph.D. Degree with honors in University of Kansas Medical Center. Julia currently is an Assistant Professor in Toxicology in the Department of Environmental and Occupational Health Sciences. She is a recipient of the Sheldon D. Murphy Endowed C ...
Regulation of Ovule Development
... REVOLUTA (REV) (and other related genes), expressed laterally, could be these factors (Figure 2A). However, it is unlikely that these factors contribute directly to identity in this region. A double mutant of the ettin and tsl genes produces structures that could be interpreted as naked placentas: t ...
... REVOLUTA (REV) (and other related genes), expressed laterally, could be these factors (Figure 2A). However, it is unlikely that these factors contribute directly to identity in this region. A double mutant of the ettin and tsl genes produces structures that could be interpreted as naked placentas: t ...
lilliputian - Development - The Company of Biologists
... **rafHM7: a temperature-sensitive hypomorphic raf allele with reduced transcription from the raf gene (Dickson et al., 1992; Melnick et al., 1993). ...
... **rafHM7: a temperature-sensitive hypomorphic raf allele with reduced transcription from the raf gene (Dickson et al., 1992; Melnick et al., 1993). ...
Making Headway: The Roles of Hox Genes and Neural
... The kreisler mouse was identified due to its circling behavior, a phenotype, which is usually associated with inner ear defects[65]. Kreisler expression is initiated at 8.5dpc in the prospective r5 territory and is later expressed in r5 and r6 after which it is quickly downregulated in both rhombome ...
... The kreisler mouse was identified due to its circling behavior, a phenotype, which is usually associated with inner ear defects[65]. Kreisler expression is initiated at 8.5dpc in the prospective r5 territory and is later expressed in r5 and r6 after which it is quickly downregulated in both rhombome ...
Table 3 - HAL Descartes
... screen for SOX10 gene deletions. Briefly, the 3 coding exons of the SOX10 gene, exon 4 of POLR2F and 4 regions located 5’ of SOX10 were amplified in two multiplex reactions. The beginning of exon 3 and the middle of the exon 5 coding sequences are not covered by the amplicons, however a deletion res ...
... screen for SOX10 gene deletions. Briefly, the 3 coding exons of the SOX10 gene, exon 4 of POLR2F and 4 regions located 5’ of SOX10 were amplified in two multiplex reactions. The beginning of exon 3 and the middle of the exon 5 coding sequences are not covered by the amplicons, however a deletion res ...
Genetic and biochemical analysis of the adenylyl cyclase of
... Figure 1. Plasmid maps. pPC2 contains the S. pombe adenylyl cyclase gene in the pUC1 18 vector and has been previously described (Young et al., 1989). The positions of sites for Stu (St), Pst I (P), Hpa I (Hp), BamHI (B), EcoRl (R), Nco I (N), Hindlil (H), Sph I (Sp), Sal I (S), Xba I (X), Sma I (Sm ...
... Figure 1. Plasmid maps. pPC2 contains the S. pombe adenylyl cyclase gene in the pUC1 18 vector and has been previously described (Young et al., 1989). The positions of sites for Stu (St), Pst I (P), Hpa I (Hp), BamHI (B), EcoRl (R), Nco I (N), Hindlil (H), Sph I (Sp), Sal I (S), Xba I (X), Sma I (Sm ...
Standards and guidelines for the interpretation of sequence
... A uniform nomenclature, informed by a set of standardized criteria, is recommended to ensure the unambiguous designation of a variant and enable effective sharing and downstream use of genomic information. A standard gene variant nomenclature (http://www.hgvs.org/mutnomen) is maintained and versione ...
... A uniform nomenclature, informed by a set of standardized criteria, is recommended to ensure the unambiguous designation of a variant and enable effective sharing and downstream use of genomic information. A standard gene variant nomenclature (http://www.hgvs.org/mutnomen) is maintained and versione ...
Wheat, Fusarium toxins and disease: the good, the bad and the ugly
... crop in Canada, with Manitoba exporting wheat to approximately 66 different countries. It is processed into flour, cereal food, animal feed and industrial products such as ethanol. ¾THE BAD: Fusarium head blight (FHB) is the most serious disease in wheat around the world. Fusarium graminearum is the ...
... crop in Canada, with Manitoba exporting wheat to approximately 66 different countries. It is processed into flour, cereal food, animal feed and industrial products such as ethanol. ¾THE BAD: Fusarium head blight (FHB) is the most serious disease in wheat around the world. Fusarium graminearum is the ...
CIRCADIAN RHYTHMS IN PLANTS C Robertson McClung
... CAB). This list continues to grow (75, 95) and it seems likely that microarray analysis should soon identify most genes showing circadian oscillations in mRNA abundance. Initial estimates suggest that from 5% to 6% of Arabidopsis genes are rhythmically expressed (46a). This is a far cry from the app ...
... CAB). This list continues to grow (75, 95) and it seems likely that microarray analysis should soon identify most genes showing circadian oscillations in mRNA abundance. Initial estimates suggest that from 5% to 6% of Arabidopsis genes are rhythmically expressed (46a). This is a far cry from the app ...
Network properties of human disease genes with pleiotropic effects
... profiles with their interactors could be explained by different biological functions. Hence, we used Gene Ontology (GO) to functionally characterize the essential and phenodiv genes for their cellular component, molecular function and biological process (Additional files 1 and 2). GO analysis of ess ...
... profiles with their interactors could be explained by different biological functions. Hence, we used Gene Ontology (GO) to functionally characterize the essential and phenodiv genes for their cellular component, molecular function and biological process (Additional files 1 and 2). GO analysis of ess ...
jing is required for wing development and to establish the
... antennal and eye development, and, together with its partner gene extradenticle (exd), encodes a cofactor for the Hox proteins (ALDAZ et al. 2005; AZPIAZU and MORATA 2000; CASARES and MANN 1998; CASARES and MANN 2000; DONG et al. 2000; MANN and AFFOLTER 1998; PICHAUD and CASARES 2000). tsh also has ...
... antennal and eye development, and, together with its partner gene extradenticle (exd), encodes a cofactor for the Hox proteins (ALDAZ et al. 2005; AZPIAZU and MORATA 2000; CASARES and MANN 1998; CASARES and MANN 2000; DONG et al. 2000; MANN and AFFOLTER 1998; PICHAUD and CASARES 2000). tsh also has ...
Supplemental Material
... 1993; VIEIRA et al. 1997). End sequences from 593 of these P1 clones that map to unique sites within the genome were generated to anchor the assembly onto the polytene chromosome map. In cases where a reference sequence of D. virilis was available for the in situ localized probe, position of the seq ...
... 1993; VIEIRA et al. 1997). End sequences from 593 of these P1 clones that map to unique sites within the genome were generated to anchor the assembly onto the polytene chromosome map. In cases where a reference sequence of D. virilis was available for the in situ localized probe, position of the seq ...
controlling flowering time and plant height in
... more additional QTL in the same linkage group as the QTL detected by marker-regression. The sizes and locations of the additional QTL are not known. ...
... more additional QTL in the same linkage group as the QTL detected by marker-regression. The sizes and locations of the additional QTL are not known. ...
Profile of Edward M. De Robertis - Howard Hughes Medical Institute
... follow in his father’s footsteps. “Consequently, I did not have to invest any energy in choosing a career,” he says. Students interested in biology were steered toward the field of medicine, so De Robertis went down that path. He earned a degree in medicine in 1971 from the University of Uruguay’s Sc ...
... follow in his father’s footsteps. “Consequently, I did not have to invest any energy in choosing a career,” he says. Students interested in biology were steered toward the field of medicine, so De Robertis went down that path. He earned a degree in medicine in 1971 from the University of Uruguay’s Sc ...
PDF
... talpid2 and talpid3 have similar limb phenotypes, yet the craniofacial phenotypes are distinct. talpid3 has severe hypotelorism, a hypoplastic frontonasal mass superior to the eyes, medially fused nasal placodes, a narrow and peg-like lower beak, and an oral cavity that is divided in two by the maxi ...
... talpid2 and talpid3 have similar limb phenotypes, yet the craniofacial phenotypes are distinct. talpid3 has severe hypotelorism, a hypoplastic frontonasal mass superior to the eyes, medially fused nasal placodes, a narrow and peg-like lower beak, and an oral cavity that is divided in two by the maxi ...
Costimulatory receptors in jawed vertebrates: Conserved
... (Tetraodon nigroviridis) and zebrafish (Danio rerio). In zebrafish, it was not possible to find sequences corresponding to exons 3 and 4 (encoding transmembrane and intracytoplasmic region) from the available genome assembly. The Ensembl zebrafish genome assembly (v36) had two copies of CD28 exons 1 and ...
... (Tetraodon nigroviridis) and zebrafish (Danio rerio). In zebrafish, it was not possible to find sequences corresponding to exons 3 and 4 (encoding transmembrane and intracytoplasmic region) from the available genome assembly. The Ensembl zebrafish genome assembly (v36) had two copies of CD28 exons 1 and ...
A Fitness-Independent Evolvability Measure for Evolutionary
... most existing evolvability measures are more or less fitnessdependent. Hence, it would be interesting to examine evolvability of developmental models independent of a problemspecific fitness function. In addition, most existing evolvability measures are suggested for discrete direct or developmental ...
... most existing evolvability measures are more or less fitnessdependent. Hence, it would be interesting to examine evolvability of developmental models independent of a problemspecific fitness function. In addition, most existing evolvability measures are suggested for discrete direct or developmental ...
View Full Text-PDF
... Insulin resistance is a condition of decrease body response to natural insulin level in the serum, which is currently known as a characteristic feature of T2DM and participates in deformities in all of these tissues and organs. Thepresent study was conducted to evaluate the role of TNF- and resistin ...
... Insulin resistance is a condition of decrease body response to natural insulin level in the serum, which is currently known as a characteristic feature of T2DM and participates in deformities in all of these tissues and organs. Thepresent study was conducted to evaluate the role of TNF- and resistin ...
Lanosterol Biosynthesis in the Prokaryote
... is the subject of our recent work after identifying the first proven prokaryotic sterol biosynthetic gene/protein (Jackson et al. 2002). The importance of sterols in eukaryotes is well established because they modulate membrane fluidity and also serve as precursor molecules for hormone and brassinos ...
... is the subject of our recent work after identifying the first proven prokaryotic sterol biosynthetic gene/protein (Jackson et al. 2002). The importance of sterols in eukaryotes is well established because they modulate membrane fluidity and also serve as precursor molecules for hormone and brassinos ...
Identity elements in tRNA-mediated transcription
... system. An uncharged tRNA can bind to the leader transcript, maintain the antiterminator conformation and thus promote the expression of the operon or gene. A tRNA that is charged with an amino acid on the acceptor arm, however, would not be able to bind and stabilize the antiterminator in the leade ...
... system. An uncharged tRNA can bind to the leader transcript, maintain the antiterminator conformation and thus promote the expression of the operon or gene. A tRNA that is charged with an amino acid on the acceptor arm, however, would not be able to bind and stabilize the antiterminator in the leade ...
FS406-22
... and 95°C (Fig. 1). Agitation of the culture was nec(12). Cluster 2 includes molybdenum dinitrogenase reductases from methanogens, as well as essary for growth on N2, and clusters of two or more alternative vanadium and iron-only dinitrogenase reductases (VnfH, AnfH) from Methanosarcinales cocci were ...
... and 95°C (Fig. 1). Agitation of the culture was nec(12). Cluster 2 includes molybdenum dinitrogenase reductases from methanogens, as well as essary for growth on N2, and clusters of two or more alternative vanadium and iron-only dinitrogenase reductases (VnfH, AnfH) from Methanosarcinales cocci were ...
Leukaemia Section 3q rearrangements in myeloid malignancies Atlas of Genetics and Cytogenetics
... from MDS1 and EVI1, the resulting transcript MDS1/EVI1, contains the 2 first MDS1 exons spliced in frame to EVI1 exon 2. The MDS1 gene spans approximately 230 kb. Protein The EVI1 gene encodes a sequence specific Cys2/Hys2 type 145kDa zinc finger protein, containing two sets of seven and three zing ...
... from MDS1 and EVI1, the resulting transcript MDS1/EVI1, contains the 2 first MDS1 exons spliced in frame to EVI1 exon 2. The MDS1 gene spans approximately 230 kb. Protein The EVI1 gene encodes a sequence specific Cys2/Hys2 type 145kDa zinc finger protein, containing two sets of seven and three zing ...
Identification of One BOCR Mutation and Five NF1 Mutations in Male
... expressed BCL-6 corepressor [19]. It may specifically inhibit the gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least partially by class I and II histone deacetylases [20]. Furthermore, BCL-6 co ...
... expressed BCL-6 corepressor [19]. It may specifically inhibit the gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least partially by class I and II histone deacetylases [20]. Furthermore, BCL-6 co ...
History of Discoveries in Molecular Biology
... The idea was not the product of a painstaking laboratory discipline, but was conceived while cruising in a Honda Civic on Highway 128 from San Francisco to Mendocino. "I do my best thinking while driving," the scientist with the tanned face and bleached hair once explained. For this brilliant idea b ...
... The idea was not the product of a painstaking laboratory discipline, but was conceived while cruising in a Honda Civic on Highway 128 from San Francisco to Mendocino. "I do my best thinking while driving," the scientist with the tanned face and bleached hair once explained. For this brilliant idea b ...