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View our poster (1.1 MB PDF)
View our poster (1.1 MB PDF)

... Figure 1. RNA interference (RNAi) is a highly evolutionarily conserved mechanism of gene regulation. RNAi occurs at the post-transcriptional level and is triggered by short double-stranded RNA (dsRNA), known as short interfering RNA (siRNA), which is endogenously processed from long dsRNA by the RNa ...
WUS and STM in shoot meristem regulation
WUS and STM in shoot meristem regulation

... suggesting that STM fulfils two functions: it inhibits differentiation of the cells in the embryo apex and prevents outgrowth of the cells separating the cotyledon primordia in the periphery. Repression of differentiation by STM in the SAM primordium appears to occur mainly via repression of the MYB ...
Genit 3
Genit 3

... d. with genes for the same characteristics at corresponding loci. One homologous chromosome is inherited from the organism's mother; the other from the organism's father.[1] They are usually not identical. Each chromosome in the pair contains genes for the same biological features, such as eye color ...
Charcot-Marie
Charcot-Marie

... identified. This means that the electrical test (nerve conduction studies) is still often very useful in making the diagnosis. An exception is when there is a clear family history of autosomal dominant inheritance (see below), when DNA testing for the commonest form of CMT (type 1A) might be perform ...
as Adobe PDF - Edinburgh Research Explorer
as Adobe PDF - Edinburgh Research Explorer

... Figure 1. Biniou-bound enhancers drive expression in diverse spatial domains. (A) Schematic diagram showing the experimental design. The green arrow indicates Biniou’s continuous expression from stage 10 (∼6 h after egg laying) to the end of embryogenesis. ChIP-on-chip experiments were conducted at ...
Gene Expression Databases - HSLS
Gene Expression Databases - HSLS

... Development of gene ontology based tools ...
Biology Final Exam Review Questions Answer Section SHORT
Biology Final Exam Review Questions Answer Section SHORT

... STA: CA.BIO.4.d TOP: Foundation Edition BLM: comprehension 46. ANS: A sperm that has 23 chromosomes fertilizes an egg that has 23 chromosomes resulting in a 23 pairs of chromosomes (46 total) in the autosomal cells of the individual. PTS: 1 DIF: L2 REF: p. 392 | p. 393 OBJ: 14.1.1 Identify the types ...
Comparative Analysis Using DNA Microarrays: Sensitivity
Comparative Analysis Using DNA Microarrays: Sensitivity

... Application within strategy of recurrence (first approximation)  Let p denote probability that SLRMEASURE for a given gene will exceed a threshold l on a single comparison  Then the probability that SLRMEASURE will exceed l on all 2n-1 independent measurements will be ~ p2n–1 ...
SLOs - 3.3 Genetics small - Miss Jan`s Science Wikispace
SLOs - 3.3 Genetics small - Miss Jan`s Science Wikispace

...  Explain how metabolic pathways are regulated in prokaryotes through gene induction  Explain what a repressor is  Explain how the end-product of a metabolic pathway can activate a repressor and switch genes off (gene repression)  Explain the difference between an inducible and non-inducible syst ...
PDF
PDF

... and polarized light sensors (Hardie, 1985). According to their differentiated function, R1-6 innervate the first OL neuropil, which is the lamina, whereas R7 and R8 axons run across the lamina to innervate the neuropil beneath, which is the medulla. Next, the lobula and lobula plate (together called ...
PDF
PDF

... evolution in honeybees. In support of this previous studies found elevated frequencies of WS mutations, particularly in regions of high GC content [2,39]. A striking and unique feature of the honeybee genome is the over-representation of CpG dinucleotides [26]. The statistic CpGO/E measures the freq ...
Input signals to the plant circadian clock
Input signals to the plant circadian clock

... common pathway or process are expressed at the same phase, suggesting that the phase might be important for the function of that process. Many genes encoding enzymes of phenylpropanoid biosynthesis had peak RNA levels before dawn, perhaps because it is advantageous to accumulate photoprotective ¯avo ...
download file
download file

... complementation, and deficiency testing were performed by standard genetic methods (Herman and Horvitz, 1980). Aldicarb, 2-methyl-2[methylthio]proprionaldehyde O-[methylcarbamoyl]oxime, was obtained from Chem Services (West Chester, PA) and was prepared as a 100 mM stock solution in 70% ethanol. Ald ...
MyGene.info Documentation
MyGene.info Documentation

... Each individual gene object contains an “_id” field as the primary key. The value of the “_id” field is the NCBI gene ID (the same as “entrezgene” field, but as a string) if available for a gene object, otherwise, Ensembl gene ID is used (e.g. those Ensembl-only genes). Here is an example. We recomm ...
The Wnt code: cnidarians signal the way
The Wnt code: cnidarians signal the way

... bilaterian evolution. In insects and nematodes only seven and five wnt genes can be identified in the Drosophila and Caenorhabditis genome. This clearly shows that there is no simple correlation between the increase in morphological complexity and the repertoire in genes of genomes (Kusserow et al., 2 ...
Fitness landscapes of gene regulation in variable - UvA-DARE
Fitness landscapes of gene regulation in variable - UvA-DARE

... pressures in an environment that is fluctuating, which makes that there are many more potential parameters to optimize. Optimality can, for example, concern the nature of the environmental fluctuations (regular or stochastic), their time scales, the strength of selection in each environmental state, a ...
Genetic Homologies between Flagellar Antigens of
Genetic Homologies between Flagellar Antigens of

... Hybrids of Salmonella abony and Escherichia coli combining antigenic characteristics of both parents have been obtained. In this case the antigens, each determined by distinct structural genes, retain their original identity. Only flagellar antigens have so far been studied, and these strains would ...
Par-1
Par-1

... machinery Many components of RNAi machinery have been identified through genetic screening for RNAi defective mutants and through biochemical studies using cell extracts (e.g. Drosophila embryo extract). ...
Altered Pax gene expression in murine notochord mutants: the
Altered Pax gene expression in murine notochord mutants: the

... review see Griineberg, 1963) and floor plate (Bovolenta and Dodd, 1991; Theiler, 1959) in their posterior body region, whereas in the anterior region the notochord degeneration leaves both vertebral column and neural tube almost unaffected. In Pintail (It) animals the ...
Engrailed cooperates with extradenticle and homothorax to repress
Engrailed cooperates with extradenticle and homothorax to repress

... En carries out these functions, at least in part, by repressing downstream target genes (Smith and Jaynes, 1996; Tolkunova et al., 1998). It has two well-characterized repression domains, one of which binds the Groucho co-repressor complex (Han and Manley, 1993; Jaynes and O’Farrell, 1988; Jaynes an ...
SALSA MLPA probemix P018-F1 SHOX - MRC
SALSA MLPA probemix P018-F1 SHOX - MRC

... within the PAR1 region (pseudoautosomal region 1) which covers the 3000 kb of the X and Y chromosomes next to the p-telomere. This P018-F1 SHOX probemix contains probes for each exon of the human SHOX gene, as well as a probe just before the SHOX promoter region. In addition, several probes are pres ...
Full Text  - The International Journal of Developmental Biology
Full Text - The International Journal of Developmental Biology

... stages is represented on Figure 1. When microspores initiate meiosis, coenocytic masses are established by enlarged plasmodesmata, the cytomictic channels (Fig. 1B), which create a cytoplasmic continuum between groups of cells. This way, there is an effective synchronization during microsporogenesis ...
Scientific and Standardization Committee Communication Protein S
Scientific and Standardization Committee Communication Protein S

... completely abrogated protein S expression, whereas others did express, albeit at a reduced level. This suggests that each mutation may have an individual effect on phenotype and that broad generalisation will not be possible (S. Rezende, Personal Communication). Thus, evidence is accumulating that t ...
Taxonomic evaluation of the Streptomyces griseus clade using
Taxonomic evaluation of the Streptomyces griseus clade using

... [email protected] ...
View Tutorial
View Tutorial

... differences between the sequences. Click on View → Coloring → Apply to All. Then click View → Coloring → Sequence Similarity → BLOSUM80. The sequences will now be colored by sequence similarity using the BLOSUM 80 substitution matrix. Take a moment to examine the resulting alignment. The dark blue c ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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