Understanding the pathological manifestations of aromatase excess
... Recent studies have revealed that promoters of so-called housekeeping genes are recruited for the aberrant expression of aromatase in AEXS [1,7,8]. Thus, aromatase is probably expressed continuously and ubiquitously in all somatic cells, as are housekeeping genes, which is in contrast to the continu ...
... Recent studies have revealed that promoters of so-called housekeeping genes are recruited for the aberrant expression of aromatase in AEXS [1,7,8]. Thus, aromatase is probably expressed continuously and ubiquitously in all somatic cells, as are housekeeping genes, which is in contrast to the continu ...
Unit II presentation
... • Also presents as neonatal jaundice anaemia Chronic non-spherocytic haemolytic anaemia • The precise mechanism by which increased sensitivity to oxidative damage leads to haemolysis is not fully known. • The sequence of events after an exogenous trigger factor is present is also unknown ...
... • Also presents as neonatal jaundice anaemia Chronic non-spherocytic haemolytic anaemia • The precise mechanism by which increased sensitivity to oxidative damage leads to haemolysis is not fully known. • The sequence of events after an exogenous trigger factor is present is also unknown ...
Ribotyping of Clostridium perfringens from industrially produced
... Molecular epidemiology of Yersinia enterocolitica O3 infections: use of chromosomal DNA restriction fragment length polymorphism of rRNA genes. Journal of Clinical Microbiology 29, 2368–2374. Esteban, E.K., Snipes, D., Hird, R., Kasten, and Kinde, H. (1993) Use of ribotyping for characterization of ...
... Molecular epidemiology of Yersinia enterocolitica O3 infections: use of chromosomal DNA restriction fragment length polymorphism of rRNA genes. Journal of Clinical Microbiology 29, 2368–2374. Esteban, E.K., Snipes, D., Hird, R., Kasten, and Kinde, H. (1993) Use of ribotyping for characterization of ...
X-Chromosome dosage compensation
... (XO or XY) and females (XX) to differ in their dose of X chromosomes. In each species, an essential X chromosome-wide process called dosage compensation ensures that somatic cells of either sex express equal levels of X-linked gene products. The strategies used to achieve dosage compensation are div ...
... (XO or XY) and females (XX) to differ in their dose of X chromosomes. In each species, an essential X chromosome-wide process called dosage compensation ensures that somatic cells of either sex express equal levels of X-linked gene products. The strategies used to achieve dosage compensation are div ...
Document
... adding to this area of essential knowledge by studying how the plant hormone cytokinin is involved in controlling leaf development and expansion. Both cytokinin mode of action and leaf development are important areas that are poised to be experimentally explored. Plant hormones are vital compounds t ...
... adding to this area of essential knowledge by studying how the plant hormone cytokinin is involved in controlling leaf development and expansion. Both cytokinin mode of action and leaf development are important areas that are poised to be experimentally explored. Plant hormones are vital compounds t ...
ABSTRACT Using a bioinformatics approach to identify genes that
... done by GeneWeaver’s identifying the other gene sets within the maximal cliques that a gene set of interest occupies. The Jaccard index can be used to determine the degree of similarity between two gene sets. Jaccard indexes are more meaningfully visualized using the Jaccard Overlap Tool, which repr ...
... done by GeneWeaver’s identifying the other gene sets within the maximal cliques that a gene set of interest occupies. The Jaccard index can be used to determine the degree of similarity between two gene sets. Jaccard indexes are more meaningfully visualized using the Jaccard Overlap Tool, which repr ...
Evolutionary dynamics of RNA-like replicator systems
... Interestingly, a similar situation exists in RNA and DNA. RNA and DNA are chemically very similar to each other, the only difference being the presence or absence of one oxygen atom per nucleotide. Although RNA molecules are the only templates from which proteins are translated in the cell, DNA can ...
... Interestingly, a similar situation exists in RNA and DNA. RNA and DNA are chemically very similar to each other, the only difference being the presence or absence of one oxygen atom per nucleotide. Although RNA molecules are the only templates from which proteins are translated in the cell, DNA can ...
Risk assessment - Office of the Gene Technology Regulator
... might give rise to harm to people or the environment. These 16 events included consideration of whether, or not, expression of the introduced genes could result in products that are toxic or allergenic to people or other organisms, alter characteristics that may impact on the spread and persistence ...
... might give rise to harm to people or the environment. These 16 events included consideration of whether, or not, expression of the introduced genes could result in products that are toxic or allergenic to people or other organisms, alter characteristics that may impact on the spread and persistence ...
Development 130, 3567-3578. - Howard Hughes Medical Institute
... Gastrulation defects in Chrd–/– mice The Chrd secreted Bmp-binding protein is expressed in the mouse node and its derivatives, notochord and pharyngeal endoderm (Fig. 1A-F). The Chrd protein contains four cysteine-rich (CR) domains, all of which are able to bind Bmps. CR1 and CR3 show the highest af ...
... Gastrulation defects in Chrd–/– mice The Chrd secreted Bmp-binding protein is expressed in the mouse node and its derivatives, notochord and pharyngeal endoderm (Fig. 1A-F). The Chrd protein contains four cysteine-rich (CR) domains, all of which are able to bind Bmps. CR1 and CR3 show the highest af ...
how to solve genetics problems
... then al of their children will express the dominant allele’s phenotype. These children would be carriers and when marrying another carrier or a homozygous recessive person, the recessive phenotype could reappear. e.g. Aa x Aa produce AA, Aa and aa. ...
... then al of their children will express the dominant allele’s phenotype. These children would be carriers and when marrying another carrier or a homozygous recessive person, the recessive phenotype could reappear. e.g. Aa x Aa produce AA, Aa and aa. ...
Exome sequencing as a tool for Mendelian disease gene discovery
... nonsense single-base substitutions or small insertion– deletions (that is, indels), are predicted to have functional consequences and/or to be deleterious14. As such, the exome represents a highly enriched subset of the genome in which to search for variants with large effect sizes. Defining the exo ...
... nonsense single-base substitutions or small insertion– deletions (that is, indels), are predicted to have functional consequences and/or to be deleterious14. As such, the exome represents a highly enriched subset of the genome in which to search for variants with large effect sizes. Defining the exo ...
2008 HSC Notes from the Marking Centre Biology
... principles and ideas. Many candidates wrote a lot of information that was not relevant to the question. Some responses showed evidence of rote learning of an anticipated answer based on a single source. These responses did not address the syllabus content and/or outcomes being assessed and hence did ...
... principles and ideas. Many candidates wrote a lot of information that was not relevant to the question. Some responses showed evidence of rote learning of an anticipated answer based on a single source. These responses did not address the syllabus content and/or outcomes being assessed and hence did ...
Gene Section JAK2 (janus kinase 2) Atlas of Genetics and Cytogenetics
... 25 exons spanning roughly 140 kb of genomic DNA; 5402 bp pre-mRNA; 6 different transcripts, putatively encoding 4 different protein isoforms. ...
... 25 exons spanning roughly 140 kb of genomic DNA; 5402 bp pre-mRNA; 6 different transcripts, putatively encoding 4 different protein isoforms. ...
Dysfunction of Wild-Type Huntingtin in Huntington
... factors (2). Various authors demonstrated that transcription factors such as CBP [cAMP-response element binding protein (CREB) binding protein], TATA binding protein, and Sin3A can be recruited into the intranuclear aggregates, thus reinforcing the hypothesis of a role for transcriptional dysregulat ...
... factors (2). Various authors demonstrated that transcription factors such as CBP [cAMP-response element binding protein (CREB) binding protein], TATA binding protein, and Sin3A can be recruited into the intranuclear aggregates, thus reinforcing the hypothesis of a role for transcriptional dysregulat ...
Exclusion of known corneal dystrophy genes in an autosomal
... Purpose: With advances in phenotyping tools and availability of molecular characterization, an increasing number of phenotypically and genotypically diverse inherited corneal dystrophies are described. We aimed to determine the underlying causative genetic mechanism in a three-generation pedigree af ...
... Purpose: With advances in phenotyping tools and availability of molecular characterization, an increasing number of phenotypically and genotypically diverse inherited corneal dystrophies are described. We aimed to determine the underlying causative genetic mechanism in a three-generation pedigree af ...
Distribution and structural variation of the she pathogenicity island in
... coli (EHEC), enteropathogenic E. coli (EPEC), enteroinvasive E. coli (EIEC), Yersinia enterocolitica and Salmonella enterica serovar Typhimurium. The study showed that the she PAI has undergone a variety of structural changes, de®ned by the presence or absence of speci®c marker genes in the PAI. The ...
... coli (EHEC), enteropathogenic E. coli (EPEC), enteroinvasive E. coli (EIEC), Yersinia enterocolitica and Salmonella enterica serovar Typhimurium. The study showed that the she PAI has undergone a variety of structural changes, de®ned by the presence or absence of speci®c marker genes in the PAI. The ...
REVIEWS
... fingers of the Snail superfamily. a | Composite of the overall structure of Snail superfamily members, which shows the relative positions of the SNAG (Snail/Gfi) domain, the zinc fingers (I–V), and the Scratch- and Slug-specific boxes. b | Consensus sequences of the different zinc fingers for the wh ...
... fingers of the Snail superfamily. a | Composite of the overall structure of Snail superfamily members, which shows the relative positions of the SNAG (Snail/Gfi) domain, the zinc fingers (I–V), and the Scratch- and Slug-specific boxes. b | Consensus sequences of the different zinc fingers for the wh ...
coloured foal booklet - British Skewbald and Piebald Association
... However, what can never be guaranteed is what type of pattern you’ll get, and whether your foal, coloured or not – is going to grow into the horse you ultimately wanted. Breeding any horse, coloured or not, is a huge responsibility, and when you are breeding for colour this responsibility is, if any ...
... However, what can never be guaranteed is what type of pattern you’ll get, and whether your foal, coloured or not – is going to grow into the horse you ultimately wanted. Breeding any horse, coloured or not, is a huge responsibility, and when you are breeding for colour this responsibility is, if any ...
Analysis of single nucleotide polymorphisms in human
... Correlation with predicted secondary structure Secondary structure predictions of the exon sequences containing the SNPs show that SNPs are found in all the secondary structural elements: helical, beta-sheet and coil regions. While the absolute number of SNPs in coils is generally more than the numb ...
... Correlation with predicted secondary structure Secondary structure predictions of the exon sequences containing the SNPs show that SNPs are found in all the secondary structural elements: helical, beta-sheet and coil regions. While the absolute number of SNPs in coils is generally more than the numb ...
color info - Bedonna`s Performance Horses
... Agouti genes and will give one to every foal, so his dark colored foals will be Bays, Browns, or Buckskins, etc. Bred to crème gene mares, the foals may be Palomino or Buckskin. He is also now tested for the 5-Panel Test, and he is Negative for all 5 diseases. CCQH LUCKY … and… ZACH BLUE Both of the ...
... Agouti genes and will give one to every foal, so his dark colored foals will be Bays, Browns, or Buckskins, etc. Bred to crème gene mares, the foals may be Palomino or Buckskin. He is also now tested for the 5-Panel Test, and he is Negative for all 5 diseases. CCQH LUCKY … and… ZACH BLUE Both of the ...
An AT-hook gene is required for palea formation and floral organ
... Consistent with this controversy of sepal equivalent organ in rice and other grasses, class A genes in rice remain difficult to determine. Similar to rice, the maize outer whorl organ identity remains elusive that molecular dissection of regulatory pathways has just started (Thompson et al., 2009; Wh ...
... Consistent with this controversy of sepal equivalent organ in rice and other grasses, class A genes in rice remain difficult to determine. Similar to rice, the maize outer whorl organ identity remains elusive that molecular dissection of regulatory pathways has just started (Thompson et al., 2009; Wh ...
Quantitative expression of cholera toxin mRNA in Vibrio cholerae
... Table 1 shows the results of cycle threshold (Ct) analysis for the CTX arrangements A, B and C and the classical strain. The mean ratios were also calculated as 0.05, 0.11 and 0.25 for the CTX arrangements A, B and C and were significantly different from that of the classical strain, which was given ...
... Table 1 shows the results of cycle threshold (Ct) analysis for the CTX arrangements A, B and C and the classical strain. The mean ratios were also calculated as 0.05, 0.11 and 0.25 for the CTX arrangements A, B and C and were significantly different from that of the classical strain, which was given ...
Mice lacking desmocollin 1 show epidermal fragility accompanied
... et al., 1998; Tselepis et al., 1998). Each constitutes a cadherin subfamily that comprises three genetic isoforms (Dsc1, 2, and 3 and Dsg1, 2, and 3) (Buxton et al., 1993). Dscs and Dsgs show tissue-specific expression: Dsc2 and Dsg2 are ubiquitous in desmosome-containing tissues, whereas Dscs 1 and ...
... et al., 1998; Tselepis et al., 1998). Each constitutes a cadherin subfamily that comprises three genetic isoforms (Dsc1, 2, and 3 and Dsg1, 2, and 3) (Buxton et al., 1993). Dscs and Dsgs show tissue-specific expression: Dsc2 and Dsg2 are ubiquitous in desmosome-containing tissues, whereas Dscs 1 and ...
Inverse correlation between SMN1 and SMN2 copy numbers
... with two copies of SMN1.4,10 We meta-analyzed published data,3,4,8,10,13,14 and updated deduced SMN1 allele frequencies5 as follows: ‘zero-copy allele’ (chromosome 5 lacking SMN1 exon 7), 9.83 10 3; ‘one-copy allele’, 9.57 10 1; ‘two-copy allele’ (chromosome 5 with two copies of SMN1 exon 7), 3. ...
... with two copies of SMN1.4,10 We meta-analyzed published data,3,4,8,10,13,14 and updated deduced SMN1 allele frequencies5 as follows: ‘zero-copy allele’ (chromosome 5 lacking SMN1 exon 7), 9.83 10 3; ‘one-copy allele’, 9.57 10 1; ‘two-copy allele’ (chromosome 5 with two copies of SMN1 exon 7), 3. ...
