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... The mutant alleles trx2, trx3 and trxL are all homozygous lethal; they fail to complement the homoeotic phenotype of trx1, as well as each others lethality. Genetic analysis suggests that all three alleles abolish most, if not all, of the wildtype function of the trx locus (Ingham, 1981); in additio ...
... The mutant alleles trx2, trx3 and trxL are all homozygous lethal; they fail to complement the homoeotic phenotype of trx1, as well as each others lethality. Genetic analysis suggests that all three alleles abolish most, if not all, of the wildtype function of the trx locus (Ingham, 1981); in additio ...
Evolution 2010 Wilkins
... fitness are likely to be quite similar in most cases. However, if we consider a pair of antagonistic loci (e.g., a paternally expressed growth enhancer and a maternally expressed growth suppressor), the simplest model permits no pattern of expression that is evolutionarily stable simultaneously at b ...
... fitness are likely to be quite similar in most cases. However, if we consider a pair of antagonistic loci (e.g., a paternally expressed growth enhancer and a maternally expressed growth suppressor), the simplest model permits no pattern of expression that is evolutionarily stable simultaneously at b ...
Phytopathology
... is an emerging methodology useful for identification of DNA fragments and may be applicable for rapid identification and detection of plant pathogens associated with plants (20,21,26). An array of species-specific oligonucleotide probes representing the various pathogens of potato, built on a solid ...
... is an emerging methodology useful for identification of DNA fragments and may be applicable for rapid identification and detection of plant pathogens associated with plants (20,21,26). An array of species-specific oligonucleotide probes representing the various pathogens of potato, built on a solid ...
Replication timing as an epigenetic mark
... chromosomes.9,10 Chromatin is assembled at the replication fork and different types of chromatin are assembled at different times during S-phase.11 Every multi-cellular organism studied to date exhibits a strong positive correlation between early replication and transcription.12 At the same time, ch ...
... chromosomes.9,10 Chromatin is assembled at the replication fork and different types of chromatin are assembled at different times during S-phase.11 Every multi-cellular organism studied to date exhibits a strong positive correlation between early replication and transcription.12 At the same time, ch ...
Fanconi anemia and RAD50 deficiency: genetic and functional
... the different types of molecular events that lead to the restoration of heterozygosity, and thereby normal function, of the self-corrected cell types in individuals constitutionally homozygous or compound heterozygous for disease causing gene mutations. ...
... the different types of molecular events that lead to the restoration of heterozygosity, and thereby normal function, of the self-corrected cell types in individuals constitutionally homozygous or compound heterozygous for disease causing gene mutations. ...
Package `BitSeq`
... analysis and differential expression analysis of RNA-seq data in two stage process. In the first stage it uses Bayesian inference methodology to infer expression of individual transcripts from individual RNA-seq experiments. The second stage of BitSeq embraces the differential expression analysis of ...
... analysis and differential expression analysis of RNA-seq data in two stage process. In the first stage it uses Bayesian inference methodology to infer expression of individual transcripts from individual RNA-seq experiments. The second stage of BitSeq embraces the differential expression analysis of ...
ACTIN-RELATED PROTEIN6 Regulates Female Meiosis By
... In flowering plants, meiocytes develop from subepidermal cells in anthers and ovules. The mechanisms that integrate generegulatory processes with meiotic programs during reproductive development remain poorly characterized. Here, we show that Arabidopsis thaliana plants deficient in ACTIN-RELATED PROT ...
... In flowering plants, meiocytes develop from subepidermal cells in anthers and ovules. The mechanisms that integrate generegulatory processes with meiotic programs during reproductive development remain poorly characterized. Here, we show that Arabidopsis thaliana plants deficient in ACTIN-RELATED PROT ...
Genetic Basis for Osmosensitivity and Genetic Instability of the Wine
... and an ABI PRISM 7000 instrument (Applied Biosystems, Carlsbad, CA). PCR reactions were conducted in triplicate using 2 µL cDNA as template for both genes of interest. IPP1 was used as a control gene, as this gene is not affected by osmotic stress (Rep et al. 1999). IPP1 was also expressed at the sa ...
... and an ABI PRISM 7000 instrument (Applied Biosystems, Carlsbad, CA). PCR reactions were conducted in triplicate using 2 µL cDNA as template for both genes of interest. IPP1 was used as a control gene, as this gene is not affected by osmotic stress (Rep et al. 1999). IPP1 was also expressed at the sa ...
NUCLEIC ACID ECONOMY IN BACTERIA INFECTED WITH
... 0.1 gin. gelatin, and HC1 to adjust to pH 7.4. Analytical Methods.--Most of the experiments required periodic measures of DNAP~ and mature phage P~. DNA-P 3~ was determined (Schmidt and Thannhauser, 1945) by precipitating a chilled 1 ml. sample of the culture in a conical tube with 9 ml. 0.3 M trich ...
... 0.1 gin. gelatin, and HC1 to adjust to pH 7.4. Analytical Methods.--Most of the experiments required periodic measures of DNAP~ and mature phage P~. DNA-P 3~ was determined (Schmidt and Thannhauser, 1945) by precipitating a chilled 1 ml. sample of the culture in a conical tube with 9 ml. 0.3 M trich ...
Isolation of COV1, a gene involved in the regulation of vascular
... The vascular system in plants forms the structural architecture required to transport solutes and water. During primary vascular development, the pattern of vascular tissue is first visualised by the appearance of the procambial cells. These procambial cells subsequently differentiate into both the ...
... The vascular system in plants forms the structural architecture required to transport solutes and water. During primary vascular development, the pattern of vascular tissue is first visualised by the appearance of the procambial cells. These procambial cells subsequently differentiate into both the ...
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... 2010). In addition, a previous study showed that the ASP is also required for formation of the gill slit (Kourakis and Smith, 2007). To test whether ASP formation is affected in Ci-Hox1-deficient animals, we made use of epidermal GFP transgenic lines (Sasakura et al., 2010) in which the disc-like or ...
... 2010). In addition, a previous study showed that the ASP is also required for formation of the gill slit (Kourakis and Smith, 2007). To test whether ASP formation is affected in Ci-Hox1-deficient animals, we made use of epidermal GFP transgenic lines (Sasakura et al., 2010) in which the disc-like or ...
17. Prof. K. P. Bhatia: Paroxysmal Movement Disorders
... dystonia/chorea lasting many hours17 and frequently precipitated by stress, fatigue, alcohol or coffee.3 Unlike PKD the episodes are infrequent with long attack-free intervals. As with PKD more males than females are affected (1.4:1) and attacks wane with age.17 An autosomal dominant pattern of inhe ...
... dystonia/chorea lasting many hours17 and frequently precipitated by stress, fatigue, alcohol or coffee.3 Unlike PKD the episodes are infrequent with long attack-free intervals. As with PKD more males than females are affected (1.4:1) and attacks wane with age.17 An autosomal dominant pattern of inhe ...
From DNA to diversity: molecular genetics and the evolution of
... the structure of DNA was discovered. Although many reasons exist to explain this omission, foremost among them is that biology first had to address another central genetic mystery a that is, which genes out of the thousands in any species control morphology? One of the most important biological disc ...
... the structure of DNA was discovered. Although many reasons exist to explain this omission, foremost among them is that biology first had to address another central genetic mystery a that is, which genes out of the thousands in any species control morphology? One of the most important biological disc ...
Preview Sample 2
... remember that an animal with a recessive phenotype must be homozygous. Thus, if you mate several red horses to each other and also mate several black horses to each other, the crosses that always yield only offspring with the parental phenotype must have been between homozygous recessives. For examp ...
... remember that an animal with a recessive phenotype must be homozygous. Thus, if you mate several red horses to each other and also mate several black horses to each other, the crosses that always yield only offspring with the parental phenotype must have been between homozygous recessives. For examp ...
Base Composition and Translational Selection are Insufficient to
... codons [1,2]. Codon bias may vary among genes of the same organism, which is associated with factors like asymmetrical mutation pressures or tissue-specific gene expression, but is relatively uniform within the most highly expressed genes [3–10]. CUB is often explained as the product of two potentia ...
... codons [1,2]. Codon bias may vary among genes of the same organism, which is associated with factors like asymmetrical mutation pressures or tissue-specific gene expression, but is relatively uniform within the most highly expressed genes [3–10]. CUB is often explained as the product of two potentia ...
Drosophila Muller F Elements Maintain a Distinct Set of Genomic
... The overall sequence improvement protocol has previously been described (Slawson et al. 2006; Leung et al. 2010). Reads placed in each fosmid region were retrieved from the National Center for Biotechnology Information Trace Archive (http://www.ncbi.nlm.nih.gov/ Traces/home/) and assembled using the ...
... The overall sequence improvement protocol has previously been described (Slawson et al. 2006; Leung et al. 2010). Reads placed in each fosmid region were retrieved from the National Center for Biotechnology Information Trace Archive (http://www.ncbi.nlm.nih.gov/ Traces/home/) and assembled using the ...
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... factor (Abe et al., 2005; Wigge et al., 2005). The resulting complex activates transcription of genes that promote floral development, including AP1, thus triggering the floral transition. Activation of FT by CO is likely to be mediated through interactions with nuclear factor Y proteins (NF-Y) – also ...
... factor (Abe et al., 2005; Wigge et al., 2005). The resulting complex activates transcription of genes that promote floral development, including AP1, thus triggering the floral transition. Activation of FT by CO is likely to be mediated through interactions with nuclear factor Y proteins (NF-Y) – also ...
The Mean Between Meme and Gene Comparison
... recognizes that the development of the gene and meme pool differ in the method and rate of mutation. Most genetic mutations occur during the process of reading and transposing DNA and sexual reproduction. Genes are generally quite stable, which is one of the key reasons for the successful formulati ...
... recognizes that the development of the gene and meme pool differ in the method and rate of mutation. Most genetic mutations occur during the process of reading and transposing DNA and sexual reproduction. Genes are generally quite stable, which is one of the key reasons for the successful formulati ...
redundancy and regulatory interactions between two
... FAR cDNA clones showed that four utilized the alternative splice site. The variation occurs within a region of the MADS-box protein known as the I-domain (Ma et al., 1991), the length and sequence composition of which have been postulated to affect the heterodimerization specificity amongst MADS-box ...
... FAR cDNA clones showed that four utilized the alternative splice site. The variation occurs within a region of the MADS-box protein known as the I-domain (Ma et al., 1991), the length and sequence composition of which have been postulated to affect the heterodimerization specificity amongst MADS-box ...
Zinc Ions and Cation Diffusion Facilitator Proteins
... with the predicted mouse ZnT-1 (Palmiter and Findley, 1995) and S. cerevisiae COT1 (Conklin et al., 1992) proteins. Predicted membrane-spanning domains are boxed and labeled with Roman numerals. Clusters of histidine residues following transmembrane domain IV are in red. In CDF-1, this region contai ...
... with the predicted mouse ZnT-1 (Palmiter and Findley, 1995) and S. cerevisiae COT1 (Conklin et al., 1992) proteins. Predicted membrane-spanning domains are boxed and labeled with Roman numerals. Clusters of histidine residues following transmembrane domain IV are in red. In CDF-1, this region contai ...
Virp1 Is a Host Protein with a Major Role in Potato - IMBB
... Viroids are small, circular, single-stranded RNA molecules that, while not coding for any protein, cause several plant diseases. Viroids rely for their infectious cycle on host proteins, most of which are likely to be involved in endogenous RNA-mediated phenomena. Therefore, characterization of host ...
... Viroids are small, circular, single-stranded RNA molecules that, while not coding for any protein, cause several plant diseases. Viroids rely for their infectious cycle on host proteins, most of which are likely to be involved in endogenous RNA-mediated phenomena. Therefore, characterization of host ...
Epigenetic inheritance of acquired traits through sperm RNAs and
... (tsRNAGly(GCC))11 could change early embryonic gene expression, indicating that sperm tsRNAs play an active part in the transmission of paternally acquired traits by reshaping early embryonic development. A recent study revealed that sperm tsRNAs show a dramatic increase in abundance during late spe ...
... (tsRNAGly(GCC))11 could change early embryonic gene expression, indicating that sperm tsRNAs play an active part in the transmission of paternally acquired traits by reshaping early embryonic development. A recent study revealed that sperm tsRNAs show a dramatic increase in abundance during late spe ...
Gbx2 is required for the morphogenesis of the mouse inner ear
... duct and an enlargement of the membranous labyrinth. The enlarged membranous labyrinth could be secondary to the loss of the endolymphatic duct, which has been shown to be important in maintaining fluid homeostasis within the membranous labyrinth (Everett et al., 2001; Hulander et al., 2003). In add ...
... duct and an enlargement of the membranous labyrinth. The enlarged membranous labyrinth could be secondary to the loss of the endolymphatic duct, which has been shown to be important in maintaining fluid homeostasis within the membranous labyrinth (Everett et al., 2001; Hulander et al., 2003). In add ...