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Directed Reading
Directed Reading

... chemical energy is released gradually in a series of enzyme-assisted reactions. When a log is burned, stored chemical energy is released quickly as heat and light. 12. ATP is called an energy currency because cells can “spend it” in order to carry out cellular processes that require energy. 13. Ener ...
Table of Contents - Milan Area Schools
Table of Contents - Milan Area Schools

... catalyzed by an enzyme complex attached to the inner mitochondrial membrane. • The acetyl group is added to coenzyme A to form acetyl CoA. One NADH + H+ is generated during this reaction. ...
electron transport chain
electron transport chain

... Given the relatively modest number of calories burned by anything but the most vigorous activities, why can people consume over 2,000 kilocalories a day, yet maintain a healthy body weight? ( Module 6.4) They can't, and this has led to a problem of obesity in the United States. People really should ...
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Exercise Physiology Study Guide-Test 1 History of Exercise
Exercise Physiology Study Guide-Test 1 History of Exercise

... Oxidation of Fat (Beta-Oxidation) o Lypolysis-breakdown of triglyericde into glycerol and free fatty acids (FFA’s) o Acetyle CoA enters Krebs cycle and ETC o Fat oxidation requires more oxygen and generates more energy than CHO oxidation o Once acetyl CoA enters Krebs cycle, it follows the same fate ...
Cellular Respiration
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... higher positive charge in the intermembrane space than in the matrix, and a chemical gradient created by a higher concentration of protons in the intermembrane space. • The electrochemical gradient stores free energy; the protonmotive force (PMF). • The mitochondrial membrane is almost impermeable t ...
EXAM 2 Fall2007.doc
EXAM 2 Fall2007.doc

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Oxidative Phosphorylation Goal: ATP Synthesis
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electron transport chain

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... Therefore, input of succinyl CoA provides the citric acid cycle a net gain of carbon of carbon atoms which could be used for biosynthesis (e.g. gluconeogenesis - making glucose). Acetyl CoA (2 carbon unit) enters the citric acid cycle before the loss of 2 carbon dioxide so there is no net gain of ca ...
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... tumour cells rely on anaerobic respiration even in the presence of oxygen and that this is due to some impairment of the mitochondria in these cells. One opportunity for fighting cancer may therefore be to disrupt the glycolytic pathway in cancer cells, thereby depriving them of the energy they need ...
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Cellular Respiration – Chapter 7 – Lesson 2 – Aerobic Cellular

... ­ Recall that by the end of Stage 1, glycolysis, the cell had formed 2 ATPs, 2NADHs and 2  pyruvate molecules—all in the cytoplasm ­ Stage 2 begins when the two pyruvate molecules formed in glycolysis are transported  through the two mitochondrial membranes into the matrix ...
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Physiology for Coaches

... Phoshagen system: • Provides energy at the start of exercise, in sporting terms is primarily used in short high intensity activities such as weight lifting and sprinting. In this system two reactions occur ...
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Citric acid cycle



The citric acid cycle – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle – is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate derived from carbohydrates, fats and proteins into carbon dioxide and chemical energy in the form of adenosine triphosphate (ATP). In addition, the cycle provides precursors of certain amino acids as well as the reducing agent NADH that is used in numerous other biochemical reactions. Its central importance to many biochemical pathways suggests that it was one of the earliest established components of cellular metabolism and may have originated abiogenically.The name of this metabolic pathway is derived from citric acid (a type of tricarboxylic acid) that is consumed and then regenerated by this sequence of reactions to complete the cycle. In addition, the cycle consumes acetate (in the form of acetyl-CoA) and water, reduces NAD+ to NADH, and produces carbon dioxide as a waste byproduct. The NADH generated by the TCA cycle is fed into the oxidative phosphorylation (electron transport) pathway. The net result of these two closely linked pathways is the oxidation of nutrients to produce usable chemical energy in the form of ATP.In eukaryotic cells, the citric acid cycle occurs in the matrix of the mitochondrion. In prokaryotic cells, such as bacteria which lack mitochondria, the TCA reaction sequence is performed in the cytosol with the proton gradient for ATP production being across the cell's surface (plasma membrane) rather than the inner membrane of the mitochondrion.
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