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Chapter 1 - Research Explorer
Chapter 1 - Research Explorer

... 1998). The degradation of these compounds results in the formation of important metabolites, which are vital in biochemical processes (e.g. in the biosynthesis of lipids), as well as in energy production (via the Krebs cycle and ketone body production). The degradation of the BCAAs starts with their ...
Tryptophan synthase uses an atypical mechanism to achieve
Tryptophan synthase uses an atypical mechanism to achieve

IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS)
IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS)

... cassava peels at a mixing ratio of 1:1 had significant effect in increasing average cumulative biogas yield. They posited that substrates with very high C/N ratio would produce very low biogas (Table 4). However, when codigested with materials with a low C/N ratio, stabilize the ratio to an optimal ...
The metabolism of photosynthetically fixed
The metabolism of photosynthetically fixed

... photosynthetically fixed carbon released from its “symbiotic” chloroplasts. Previous experimental investigations of E. uiridis have been described by Trench & Smith (1970), Trench, Boyle & Smith (1973a, b, 1974), Gallop (1974) and Hinde & Smith (1972, 1975). These show that the animal contains undam ...
CX3 creatine
CX3 creatine

... Creatine plays a vital role in energy production by recycling ATP (adenosine triphosphate) in muscles. ATP is the body’s major molecule that produces “explosive” chemical energy within cells and is also known as “molecular currency” since it transfers energy within all cells of the body. Approximate ...
bile acids - The Vespiary
bile acids - The Vespiary

and Functions of y-Aminobutyric Acid
and Functions of y-Aminobutyric Acid

Contents - Elsevier
Contents - Elsevier

PDF
PDF

Redacted for Privacy
Redacted for Privacy

... Becker, Dr. Sonia Anderson, Dr. Daniel Arp and Dr. Thomas Savage. Dr. Savage, in particular, for guiding me through several editions of this work. His patience and standards are to be commended. I wish to thank both Dr. Becker and Dr. Anderson for introducing me into the study of proteins; and to Dr ...
Correlation of an Immobilized Digestive Enzyme Assay with Poultry
Correlation of an Immobilized Digestive Enzyme Assay with Poultry

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Minimum electrophilicity principle in Lewis acid–base complexes of
Minimum electrophilicity principle in Lewis acid–base complexes of

... To reinvestigate the acidity strength of some boron trihalides (BX3; X = F, Cl and Br) from theoretical point of view, two sets of Lewis bases (weak and strong), which can form stable compounds with these acids, are considered here. It is expected that more stable complexes are formed by stronger ac ...
Structural and Biochemical Characterization of a Bifunctional
Structural and Biochemical Characterization of a Bifunctional

... The structure of the protein was determined via single wavelength anomalous dispersion (SAD). Analysis of the X-ray data measured from the selenomethionine-labeled crystals with SHELXD revealed 54-selenium atoms.10 Visual inspection of the anomalous difference map led to the location of six additiona ...
and Schizosaccharomyces pombe
and Schizosaccharomyces pombe

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Amino Acid Sequencing
Amino Acid Sequencing

... undetected can be determined. Biologists believe that the greater the similarity between the amino acid sequences of two organisms, the closer their relationship. Conversely, the greater the differences, the more distant the relationship. Furthermore, biologists have found that such biochemical evid ...
Being right on Q: shaping eukaryotic evolution
Being right on Q: shaping eukaryotic evolution

... formation is not a peripheral bacterial phenomenon anymore: it now occurs in the middle of the new organism. Secondly, alternatively using different catabolic substrates, as described above, gave rise to more ROS formation [5,6]. Why should this be so? Relative amounts of the intermediates FADH2 and ...
Continuous Production of Ethanol via a Magnetically Stabilized
Continuous Production of Ethanol via a Magnetically Stabilized

... continuous, bioreactor. This was achieved by the entrapment of Saccharomyces Cerevisiae yeast in calcium alginate beads, doped with magnetite. The bioreactor was constructed in-house and consisted of a flow through chamber in which the beads were stabilized with an array of magnets. Ethanol producti ...
Active Learning Questions
Active Learning Questions

... can exist in significant amounts in aqueous solutions? 23. How many significant figures are there in the following numbers: 10.78, 6.78, 0.78? If these were pH values, to how many significant figures can you express the [H]? Explain any discrepancies between your answers to the two questions. 24. I ...
Contribution of 13C-NMR spectroscopy to the elucidation of
Contribution of 13C-NMR spectroscopy to the elucidation of

... pyruvate and oxaloacetate are formed, respectively. These intermediates can be partially oxidized to acetate and partially reduced to propionate leading to stoichiometries as given in Table 2 (Eqs. 1 and 2). Also glutamate may be converted reductively to propionate (Table 2, Eq. 3). This was describ ...
A Systematic Approach to Enzyme Assay Optimization, Illustrated by
A Systematic Approach to Enzyme Assay Optimization, Illustrated by

Energy Metabolism Regulating Mammalian Oocyte
Energy Metabolism Regulating Mammalian Oocyte

... pathway and Ca2+ homeostasis (Van Blerkom, 2004, Ramalho-Santos et al., 2009). Dysfunction of mitochondria has been linked to several pathologies, such as heart diseases (Facecchia et al., 2011; Perrelli, et al. 2011), neurodegenerative (Facecchia et al., 2011) and infertility (Ramalho-Santos et al. ...
Metabolism of [14C]glutamate and [14C]glutamine by
Metabolism of [14C]glutamate and [14C]glutamine by

... indicating that the mycelium did not retain labelled amino acids in the apoplastic space. Part of the radioactivity removed from the feeding solution could not be found inside the mycelium (Tables 1 and 2). This proportion increased with time and may be due to formation of volatile compounds in the ...
Electron Transport, NADPH Turnover, and Metabolism of Reactive
Electron Transport, NADPH Turnover, and Metabolism of Reactive

... NDex(NADH), as reviewed previously (76). In some investigations (e.g. 60), platanetin was used as a diagnostic inhibitor to identify NDex activity. However, platanetin was later shown to inhibit all five NAD(P)H dehydrogenases in plant mitochondria, with KI value of 4–15 µM for the four rotenone-ins ...
BioFiles v5 n1 - Sigma
BioFiles v5 n1 - Sigma

... stronger affinity for the Siglec binding site. Terminal sialic acids also protect penultimate glycoconjugate sugars, primarily galactose, from carbohydrate binding receptors such as galectins (vertebrate galactose-specific lectins) that are associated with inflammation, apoptosis, and immune cell re ...
Effects of dietary polyunsaturated fatty acids on
Effects of dietary polyunsaturated fatty acids on

... Storey, 1995; Frank and Storey, 1996) and are within the range of natural S. lateralis diets [as calculated by Munro and Thomas (Munro and Thomas, 2004)]. Custom diets were formulated by Purina Mills Test Diet division (Richmond, IN, USA) and supplied by Ren’s Feed (Oakville, ON, Canada). All diets ...
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Citric acid cycle



The citric acid cycle – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle – is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate derived from carbohydrates, fats and proteins into carbon dioxide and chemical energy in the form of adenosine triphosphate (ATP). In addition, the cycle provides precursors of certain amino acids as well as the reducing agent NADH that is used in numerous other biochemical reactions. Its central importance to many biochemical pathways suggests that it was one of the earliest established components of cellular metabolism and may have originated abiogenically.The name of this metabolic pathway is derived from citric acid (a type of tricarboxylic acid) that is consumed and then regenerated by this sequence of reactions to complete the cycle. In addition, the cycle consumes acetate (in the form of acetyl-CoA) and water, reduces NAD+ to NADH, and produces carbon dioxide as a waste byproduct. The NADH generated by the TCA cycle is fed into the oxidative phosphorylation (electron transport) pathway. The net result of these two closely linked pathways is the oxidation of nutrients to produce usable chemical energy in the form of ATP.In eukaryotic cells, the citric acid cycle occurs in the matrix of the mitochondrion. In prokaryotic cells, such as bacteria which lack mitochondria, the TCA reaction sequence is performed in the cytosol with the proton gradient for ATP production being across the cell's surface (plasma membrane) rather than the inner membrane of the mitochondrion.
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