Entrez Gene - Galter Health Sciences Library
... Library of Medicine (NLM) at the National Institutes of Health (NIH). The NCBI website contains several free computerized information-processing methods of biological information. NCBI not only conducts research on biomedical problems at the molecular level using mathematical and computational metho ...
... Library of Medicine (NLM) at the National Institutes of Health (NIH). The NCBI website contains several free computerized information-processing methods of biological information. NCBI not only conducts research on biomedical problems at the molecular level using mathematical and computational metho ...
What_Is_Ontology_Bos.. - Buffalo Ontology Site
... • in what part of the normal body? • in what anatomical abnormality? ...
... • in what part of the normal body? • in what anatomical abnormality? ...
Operon: Lac trp Is the metabolic pathway anabolic or catabolic
... off when there is no lactose in the cell. The lac operon would be on when lactose is present and there is little or no glucose in the cell. However, the lac operon would be off (or operating at very low levels) even when lactose is present if sufficient glucose is simultaneously present. The trp ope ...
... off when there is no lactose in the cell. The lac operon would be on when lactose is present and there is little or no glucose in the cell. However, the lac operon would be off (or operating at very low levels) even when lactose is present if sufficient glucose is simultaneously present. The trp ope ...
Auxin-binding proteins without KDEL sequence in the moss Funaria
... labelling approaches were used. The results presented here reveal the presence of specific ABPs in Funaria. Antibodies specific to corn ABP1 could detect polypeptides of 31–33 and 46 kDa, respectively. However, unlike ABP1 of corn, both these polypeptides did not contain epitopes of the classical KD ...
... labelling approaches were used. The results presented here reveal the presence of specific ABPs in Funaria. Antibodies specific to corn ABP1 could detect polypeptides of 31–33 and 46 kDa, respectively. However, unlike ABP1 of corn, both these polypeptides did not contain epitopes of the classical KD ...
Hox gene regulation by C. elegans sop-3
... previously described another gene, sop-1, identified in the same suppressor screen, which encodes a component of the transcriptional Mediator complex (Zhang and Emmons, 2000). Mutations in both sop-1 and sop-3 suppress a mutation in a cis regulatory element of the C. elegans caudal homolog, pal-1. T ...
... previously described another gene, sop-1, identified in the same suppressor screen, which encodes a component of the transcriptional Mediator complex (Zhang and Emmons, 2000). Mutations in both sop-1 and sop-3 suppress a mutation in a cis regulatory element of the C. elegans caudal homolog, pal-1. T ...
CHAPTER 4 Gene Control of Proteins
... • b. Alkaptonuria is much more common in 1st cousin marriages than marriages with unrelated partners. ...
... • b. Alkaptonuria is much more common in 1st cousin marriages than marriages with unrelated partners. ...
Gel electrophoresis - Caltech Particle Theory
... (16 picograms = 16 ' l0'r2 grams) in order to be detected. This image was taken from a home page operated by Hitachi Software (http://www.hitachi-soft.com /hitsoft/ ss/fmbio/feb. htm) ...
... (16 picograms = 16 ' l0'r2 grams) in order to be detected. This image was taken from a home page operated by Hitachi Software (http://www.hitachi-soft.com /hitsoft/ ss/fmbio/feb. htm) ...
S - www2
... Note that in both the examples of hemoglobin and serum albumin, the sedimentation coefficient gets smaller at acid pH, i.e., the protein moves more slowly in the centrifuge tube. ...
... Note that in both the examples of hemoglobin and serum albumin, the sedimentation coefficient gets smaller at acid pH, i.e., the protein moves more slowly in the centrifuge tube. ...
PPT
... • Exact-like matching achieves 0.76 F-measure (0.96 P, 0.64 R) • Approximate matching improve recall only ...
... • Exact-like matching achieves 0.76 F-measure (0.96 P, 0.64 R) • Approximate matching improve recall only ...
Regulation of the Discs Large Tumor Suppressor by a
... cell-cell contact, being rapidly degraded by the ubiquitin-proteasome pathway in isolated cells (22). However, loss of differentiated epithelial morphology and progression toward a highly transformed and metastatic phenotype of epithelial tumor cells are associated with down-regulation of hDlg prote ...
... cell-cell contact, being rapidly degraded by the ubiquitin-proteasome pathway in isolated cells (22). However, loss of differentiated epithelial morphology and progression toward a highly transformed and metastatic phenotype of epithelial tumor cells are associated with down-regulation of hDlg prote ...
lecture1.pps
... ¶ Study of the structure, biosynthesis and biology of saccharides (sugar chains or “glycans”) in nature. ¶ Glycobiology is an integrative science, crossing all subfields of chemistry, biology and medicine. ¶ Chemical analysis and biochemistry dominated the field in the early part of the century. ¶ I ...
... ¶ Study of the structure, biosynthesis and biology of saccharides (sugar chains or “glycans”) in nature. ¶ Glycobiology is an integrative science, crossing all subfields of chemistry, biology and medicine. ¶ Chemical analysis and biochemistry dominated the field in the early part of the century. ¶ I ...
Supplementary Results dN/dS Complete results for all three models
... modulating antigenic responses in the host, we would expect that these proteins would show high rates of evolution. However, the difficulties in subdividing these variable groups into correct orthogroups may be the cause of some of these elevated dN/dS values. In our analysis, the PE and PPE gene fa ...
... modulating antigenic responses in the host, we would expect that these proteins would show high rates of evolution. However, the difficulties in subdividing these variable groups into correct orthogroups may be the cause of some of these elevated dN/dS values. In our analysis, the PE and PPE gene fa ...
can detect white spot syndrome virus (wssv
... specific to WSSV were obtained. Four were IgG1 and three were IgG2a. The yield of the monoclonal antibodies in this study was higher than those previously reported [i.e, only 3-4 clones were obtained by Poulos et al7, Anil et al16, and Lui et al9]. All MAbs were very specific and did not show any cr ...
... specific to WSSV were obtained. Four were IgG1 and three were IgG2a. The yield of the monoclonal antibodies in this study was higher than those previously reported [i.e, only 3-4 clones were obtained by Poulos et al7, Anil et al16, and Lui et al9]. All MAbs were very specific and did not show any cr ...
Capillary Electrophoresis System
... preparations). Capillary Electrophoresis (CE) is a well-established technique to separate and quantify proteins or other macromolecules (such as DNA, RNA) from complex mixtures. It also allowed the measurement of anions in solutions which can be interesting for example to determine the protein bindi ...
... preparations). Capillary Electrophoresis (CE) is a well-established technique to separate and quantify proteins or other macromolecules (such as DNA, RNA) from complex mixtures. It also allowed the measurement of anions in solutions which can be interesting for example to determine the protein bindi ...
Plant mitochondria contain the protein translocase subunits TatB
... Journal of Cell Science • Advance article ...
... Journal of Cell Science • Advance article ...
Chapter 18: REGULATION OF GENE EXPRESSION
... Regulation of Gene Expression in Eukaryotes Regulation of Chromatin Structure: Histone Acetylation a) End view of histone tails protruding outward from a nucleosome. The amino acids in the N-terminal tails are ...
... Regulation of Gene Expression in Eukaryotes Regulation of Chromatin Structure: Histone Acetylation a) End view of histone tails protruding outward from a nucleosome. The amino acids in the N-terminal tails are ...
Chapter 28 Discovery and Classification of Glycan
... function for lectins in many organisms. In eukaryotic cells, including yeast as well as higher eukaryotes, several groups of lectins are important in glycoprotein biosynthesis and intracellular movement (Chapter 39). In the endoplasmic reticulum (ER), two lectins, calnexin and calreticulin bind m ...
... function for lectins in many organisms. In eukaryotic cells, including yeast as well as higher eukaryotes, several groups of lectins are important in glycoprotein biosynthesis and intracellular movement (Chapter 39). In the endoplasmic reticulum (ER), two lectins, calnexin and calreticulin bind m ...
Connecting gene expression data from
... the delineation of gene expression profiles, in order to identify those key genes and gene clusters whose expressions alter disease state.7,8 These gene alteration patterns are identified in order to underpin the mechanism of disease. In order to experimentally determine gene expression variations a ...
... the delineation of gene expression profiles, in order to identify those key genes and gene clusters whose expressions alter disease state.7,8 These gene alteration patterns are identified in order to underpin the mechanism of disease. In order to experimentally determine gene expression variations a ...
Higher Expression Level and Lower Toxicity of Genetically Spliced
... Background: Rotavirus group A (RVA) is recognized as a major cause of severe gastroenteritis in children and new-born animals. Nonstructural protein 4 (NSP4) is responsible for the enterotoxic activity of these viruses in the villus epithelial cells. Amino acids 114-135 of NSP4 are known to form the ...
... Background: Rotavirus group A (RVA) is recognized as a major cause of severe gastroenteritis in children and new-born animals. Nonstructural protein 4 (NSP4) is responsible for the enterotoxic activity of these viruses in the villus epithelial cells. Amino acids 114-135 of NSP4 are known to form the ...
Course leader - University of Warwick
... overshoot, rewind to a higher value etc. Make sure the tip is firmly attached. Depress the plunger to the first stop, immerse tip of tip below the liquid surface (but not right to the bottom) and slowly suck up liquid (if you get air bubbles in it eject and start again). Remove the pipette from the ...
... overshoot, rewind to a higher value etc. Make sure the tip is firmly attached. Depress the plunger to the first stop, immerse tip of tip below the liquid surface (but not right to the bottom) and slowly suck up liquid (if you get air bubbles in it eject and start again). Remove the pipette from the ...
Show and tell: cell biology of pathogen invasion
... Using newly developed in vivo fluorescence imaging methods, protein–protein interactions can also be visualized in living samples, validating interactions identified by ex planta assays such as yeast two-hybrid interaction or co-immunoprecipitation studies [3–6]. The best-known imaging method for st ...
... Using newly developed in vivo fluorescence imaging methods, protein–protein interactions can also be visualized in living samples, validating interactions identified by ex planta assays such as yeast two-hybrid interaction or co-immunoprecipitation studies [3–6]. The best-known imaging method for st ...
49 fv protein synth.p65
... A gene is a length of DNA or mRNA which codes for the assembly of a specific polypeptide, and so the sequence of codons which make up the gene will determine the sequence in which amino acids are assembled into that polypeptide. This sequence of amino acids is the primary structure of the polypeptid ...
... A gene is a length of DNA or mRNA which codes for the assembly of a specific polypeptide, and so the sequence of codons which make up the gene will determine the sequence in which amino acids are assembled into that polypeptide. This sequence of amino acids is the primary structure of the polypeptid ...
Facilitation of chromatin dynamics by SARs Craig M Hart and Ulrich
... MATH-20 could interfere with this targeting. The aberrant mitotic structures induced by MATH-20 addition may be a consequence of such a mistargeting of the condensation proteins to non-SAR sequences. ...
... MATH-20 could interfere with this targeting. The aberrant mitotic structures induced by MATH-20 addition may be a consequence of such a mistargeting of the condensation proteins to non-SAR sequences. ...
Cell signaling under salt, water and cold stresses Jian
... protein [12,13•]. It was proposed that SOS3 senses cytosolic calcium changes that are elicited by salt stress [12]. Salt stress has been known to trigger a transient increase in cytosolic free calcium concentration. How this calcium signal differs from other stimuli-activated calcium signals, and ho ...
... protein [12,13•]. It was proposed that SOS3 senses cytosolic calcium changes that are elicited by salt stress [12]. Salt stress has been known to trigger a transient increase in cytosolic free calcium concentration. How this calcium signal differs from other stimuli-activated calcium signals, and ho ...
Figure S1. Chloroplast localization and topology of TerC
... thylakoid membranes of transformed Arabidopsis lines. Salt treatments were performed as described previously (Armbruster et al. 2010) using antibodies specific for GFP, Lhcb1 (Agrisera) and PsaD (Agrisera). For thermolysin treatments, isolated thylakoid membranes were resuspended in10 mM HEPES-KOH, ...
... thylakoid membranes of transformed Arabidopsis lines. Salt treatments were performed as described previously (Armbruster et al. 2010) using antibodies specific for GFP, Lhcb1 (Agrisera) and PsaD (Agrisera). For thermolysin treatments, isolated thylakoid membranes were resuspended in10 mM HEPES-KOH, ...
Protein moonlighting
Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.