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Peroxyl free radicals: potential mediators of tumor initiation and
Peroxyl free radicals: potential mediators of tumor initiation and

The kinetics of the conversion of DHA to MGO
The kinetics of the conversion of DHA to MGO

... Large amounts of sugar present with lots of capacity for H-bonding – binding other molecules that might be potential catalysts for example water pH (measure of capacity to donate H+) is moot in this environment – only measured in diluted honey Lots of other compounds present arising from the flower ...
Characterization of the mineral phosphate solubilizing activity of
Characterization of the mineral phosphate solubilizing activity of

... Traditional production of P fertilizers is based on chemical processing of insoluble mineral phosphate high-grade ore, which includes an energy intensive treatment with sulfuric acid at high temperature. This process has become an environmentally undesirable and costly aVair (Vassilev et al. 2006). ...
PhyPA: Phylogenetic method with pairwise sequence alignment
PhyPA: Phylogenetic method with pairwise sequence alignment

... ing the amino acid sequences, and then aligning the codon sequences according to the aligned amino acid sequences (Xia, 2001, Chapter 5). This approach has two shortcomings. First, given the two sequences in Fig. 1a, the approach would yield Alignment 1 (Fig. 1b, where the two sequences differing by ...
88KB
88KB

... (position 75 in the wild-type genomic ribozyme) and, as a control, in helix P2 (position 84). To assign the carbon resonances of the labeled cytosines, a separate construct was prepared with a C-to-U mutation at position 84 (Figure 2a). The annealed complex cleaved to completion when stoichiometric ...


... the glycolytic intermediate dihydroxyacetone phosphate to glycerol-3-phosphate, a reaction catalyzed by NAD⫹-dependent glycerol-3-phosphate dehydrogenase. Subsequently, the glycerol-3-phosphate formed in this reaction is hydrolyzed by glycerol-3-phosphatase to yield glycerol and inorganic phosphate. ...
Aspartame and Neuordegenerative Diseases
Aspartame and Neuordegenerative Diseases

... Gastrin (Stegink, 1984; Faber, 1989). While determining the strength or biological activity of that substance, an intermediate chemical was synthesized. That new chemical, aspartylphenylalanine-methl-ester, was given the name Aspartame. ...
Hepatic Steatosis - Arteriosclerosis, Thrombosis, and Vascular Biology
Hepatic Steatosis - Arteriosclerosis, Thrombosis, and Vascular Biology

... muscle-specific modulation of lipoprotein lipase may result in altered distribution of tissue TGs. In mice with musclespecific LPL overexpression, muscle TG content is increased, whereas liver TG content is decreased compared with wildtype mice.17 These observations in mouse models without excessive ...
Campbell`s Biology, 9e (Reece et al.) Chapter 9 Cellular Respiration
Campbell`s Biology, 9e (Reece et al.) Chapter 9 Cellular Respiration

... A) The covalent bonds in organic molecules and molecular oxygen have more kinetic energy than the covalent bonds in water and carbon dioxide. B) Electrons are being moved from atoms that have a lower affinity for electrons (such as C) to atoms with a higher affinity for electrons (such as O). C) The ...
Chapter 6 - IFSC-USP
Chapter 6 - IFSC-USP

... synaptic cleft, ensuring a rapid decrease in ACh concentration after its release from the presynaptic terminal. AChE has a very high catalytic activity (about 5000 molecules of ACh per AChE molecule per second) and hydrolyzes ACh into acetate and choline. The choline produced by ACh hydrolysis is tr ...
Cis-trans isomerization of omega dihedrals in Proteins
Cis-trans isomerization of omega dihedrals in Proteins

ADP
ADP

... Glurose-6-phosphate dehydrogenase (G6PD) is the first key enzyme for the pathway. All hydrogen atoms coming from two times of dehydrogenation are accepted by NADP+ to generate NADPH + H+ Ribose-5-phosphate is a very important intermediate molecule during the pentose phosphate pathway. ...
The malonyl CoA axis as a potential target for treating ischaemic
The malonyl CoA axis as a potential target for treating ischaemic

... into the mitochondrial matrix through a carnitinedependent transport system.8,16 This carnitine transport system involves three enzymes: CPT-I, carnitine acyltranslocase, and CPT-II. Of these three enzymes, CPT-I is rate limiting in regard to mitochondrial fatty acid uptake and is subject to potent ...
The Maillard Reaction
The Maillard Reaction

Escherichia coli ATP Synthase
Escherichia coli ATP Synthase

... kg of ATP, the cell’s energy currency, in a 75-year lifespan by converting food into useable energy by oxidation. ATP is generated by ATP synthase from ADP and inorganic phosphate (Pi) [1, 2]. ATP synthase is not only the essential means of cellular energy production in animals but also in plants an ...
Presentation 2013-201307040352
Presentation 2013-201307040352

... The complex biological functions of Carnitine derive from the non-linear interactions of many gene products, interactions that are strongly modulated by the environment ...
Post-PCR sterilization: a method to control carryover contamination
Post-PCR sterilization: a method to control carryover contamination

Fumaric acid: an overlooked form of fixed carbon in Arabidopsis and
Fumaric acid: an overlooked form of fixed carbon in Arabidopsis and

... extraction of a particular organic acid resulted in production of more than one substantial peak on the gas chromatograph, indicating that derivatization and extraction of that organic acid results in formation of more than one chemical product (Table 1). Comparison of the column retention times of ...
Design, Synthesis, and Antibacterial Properties of Dual
Design, Synthesis, and Antibacterial Properties of Dual

... First and foremost, I would like to express my deepest gratitude for my advisor, Dr. Grover Waldrop. His insight, guidance, advice, and support throughout the years have been nothing but beneficial and advantageous to my growth as a scientist. I would also like to thank Dr. Carol Taylor for her unde ...
PDF
PDF

... Thiomicrospira crunogena (Dobrinski et al., 2005) and Thiobacillus neopolitanus (Holthuijzen et al., 1986), contain carboxysomes and appear to employ a carbon concentrating mechanism, so that these adaptations are not exclusively by phototrophic organisms. No such mechanisms have been identified in a ...
Inhibitors of HIV-1 Reverse Transcriptase—Associated
Inhibitors of HIV-1 Reverse Transcriptase—Associated

... nonnucleoside RT inhibitors (NNRTIs), differing in structure and mechanism of action [1]. N(t)RTIs are RT active site-directed nucleoside analogs that require metabolic activation (phosphorylation) for antiviral activity. Once activated, NRTI-triphosphates and NtRTI-diphosphates compete with cellula ...
Inhibitors of HIV-1 Reverse Transcriptase—Associated
Inhibitors of HIV-1 Reverse Transcriptase—Associated

... nonnucleoside RT inhibitors (NNRTIs), differing in structure and mechanism of action [1]. N(t)RTIs are RT active site-directed nucleoside analogs that require metabolic activation (phosphorylation) for antiviral activity. Once activated, NRTI-triphosphates and NtRTI-diphosphates compete with cellula ...
ADP
ADP

... malate ③ allosteric inhibited by intermediates ...
PDF
PDF

... Thiomicrospira crunogena (Dobrinski et al., 2005) and Thiobacillus neopolitanus (Holthuijzen et al., 1986), contain carboxysomes and appear to employ a carbon concentrating mechanism, so that these adaptations are not exclusively by phototrophic organisms. No such mechanisms have been identified in a ...
Proteolytic processing in the secretory pathway of Aspergillus niger
Proteolytic processing in the secretory pathway of Aspergillus niger

... Proteolysis in the fungal secretory pathway Several proteases present in the secretory pathway have a proteolytic processing function. In contrast to their extracellular degrading partners, their function is needed to ensure that the proteins of interest are correctly produced. The proteolysis of th ...
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Biosynthesis



Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.
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