Lymphoid Organs in Mice T Cells from Gut
... the migratory fate of CD8+ T cells that do not meet their cognate Ag remains elusive. These naive lymphocytes, which make up most CD8+ T lymphocytes in secondary lymphoid organs, are exposed to proinflammatory cytokines secreted by activated dendritic cells (DCs) in the inflamed lymphoid tissue mili ...
... the migratory fate of CD8+ T cells that do not meet their cognate Ag remains elusive. These naive lymphocytes, which make up most CD8+ T lymphocytes in secondary lymphoid organs, are exposed to proinflammatory cytokines secreted by activated dendritic cells (DCs) in the inflamed lymphoid tissue mili ...
B-cell lymphoma, thiamine deficiency, and lactic
... solid neoplasms. While the mechanism is not entirely understood, there are many proposed theories, which include intrinsic lactate production by the tumor cells, impaired clearance of lactate in kidney or liver dysfunction, and riboflavin or thiamine deficiency (2). Tumor cells have been found to have ...
... solid neoplasms. While the mechanism is not entirely understood, there are many proposed theories, which include intrinsic lactate production by the tumor cells, impaired clearance of lactate in kidney or liver dysfunction, and riboflavin or thiamine deficiency (2). Tumor cells have been found to have ...
Chapter 7. The Cell: Cytoskeleton
... network of fibers extending throughout cytoplasm 3 main protein fibers ...
... network of fibers extending throughout cytoplasm 3 main protein fibers ...
Developmental control of blood cell migration by the Drosophila VEGF pathway. Cell 108, 865-876. pdf
... period in midembryogenesis they migrate along specific pathways to disperse throughout the body, where they function as immune and interstitial cells. Like vertebrate monocytes and macrophages, insect hemocytes phagocytose or encapsulate foreign material and apoptotic cells (Hoffmann et al., 1999). ...
... period in midembryogenesis they migrate along specific pathways to disperse throughout the body, where they function as immune and interstitial cells. Like vertebrate monocytes and macrophages, insect hemocytes phagocytose or encapsulate foreign material and apoptotic cells (Hoffmann et al., 1999). ...
Contents - Hodder Education
... Every living organism is made up of one or more cells. Cells are the basic units of life. Nothing smaller than a cell can lead an independent life and show all the characteristics of a living thing. Figures 1.1 and 1.2 show examples of plant cells viewed under the microscope. Some of a plant cell’s ...
... Every living organism is made up of one or more cells. Cells are the basic units of life. Nothing smaller than a cell can lead an independent life and show all the characteristics of a living thing. Figures 1.1 and 1.2 show examples of plant cells viewed under the microscope. Some of a plant cell’s ...
... chemotactic response towards the BAL fluid was elicited. When anti-IL-8 and anti-RANTES antibodies were added, chemotactic activity to BAL fluid from patients suffering from IPF remained unchanged, indicating that the two cytokines are not responsible for the effect observed. Finally, BAL fluid did ...
Induction of the Stem-like Cell Regulator CD44
... In this article, we found that inhibitors of Rho-associated protein kinase (ROCK) or of actomyosin cytokinesis markedly facilitated the formation of spheroids from primary colon cancers, and revealed that the CD44high cells in the spheroids share common characteristics with CSCs. Unexpectedly, a fra ...
... In this article, we found that inhibitors of Rho-associated protein kinase (ROCK) or of actomyosin cytokinesis markedly facilitated the formation of spheroids from primary colon cancers, and revealed that the CD44high cells in the spheroids share common characteristics with CSCs. Unexpectedly, a fra ...
Diatom cell division in an environmental context
... subject has never attained mainstream status. Furthermore, many of the studies were performed before whole genome sequences and tools for genetic manipulation became available for diatoms. Our view of cell division in eukaryotes has thus become somewhat distorted because the organisms most intensive ...
... subject has never attained mainstream status. Furthermore, many of the studies were performed before whole genome sequences and tools for genetic manipulation became available for diatoms. Our view of cell division in eukaryotes has thus become somewhat distorted because the organisms most intensive ...
Confocal imaging of glial cells in the intact rat optic nerve
... nerve have been computer imaged in three dimensions by laser scanning confocal microscopy of single cells, dye-filled with lysinated rhodamine dextran (LRD). Our results illustrate the first application of these techniques to an intact CNS white matter tract and provide comparative data for previous ...
... nerve have been computer imaged in three dimensions by laser scanning confocal microscopy of single cells, dye-filled with lysinated rhodamine dextran (LRD). Our results illustrate the first application of these techniques to an intact CNS white matter tract and provide comparative data for previous ...
The transcription factor Th-POK negatively regulates
... NKT17 cells were still less than 10% of the total NK1.1low V␣14i NKT cells, while in the Th-POK mutant mice they constituted the majority of the NK1.1low V␣14i NKT cells. NKT17 cells also are known to express lower amounts of the IL-2R subunit CD122 than other V␣14i NKT cells.7 The RNA microarray a ...
... NKT17 cells were still less than 10% of the total NK1.1low V␣14i NKT cells, while in the Th-POK mutant mice they constituted the majority of the NK1.1low V␣14i NKT cells. NKT17 cells also are known to express lower amounts of the IL-2R subunit CD122 than other V␣14i NKT cells.7 The RNA microarray a ...
Extended PDF
... was carried out to follow the formation of the GFP gradient at a single-cell level. gfp+ and gfp cells were mixed, applied to an agarose pad, and their growth and fluorescence were monitored. Immediately after mixing (t0 min), the fluorescence signal was confined to the gfp+ cells and no detectable ...
... was carried out to follow the formation of the GFP gradient at a single-cell level. gfp+ and gfp cells were mixed, applied to an agarose pad, and their growth and fluorescence were monitored. Immediately after mixing (t0 min), the fluorescence signal was confined to the gfp+ cells and no detectable ...
In Vitro Toxicology and Cellular Fate Determination Using
... cultures, the Biomek® 2000 workstation dispensed the CellTiter-Glo™ Reagent and then agitated the plates for two minutes on the integrated shaker. Plates were incubated for 10 minutes in the dark at room temperature before being read on an EG&G MicroLumat Luminometer. Apo-ONE™ Assays of staurosporin ...
... cultures, the Biomek® 2000 workstation dispensed the CellTiter-Glo™ Reagent and then agitated the plates for two minutes on the integrated shaker. Plates were incubated for 10 minutes in the dark at room temperature before being read on an EG&G MicroLumat Luminometer. Apo-ONE™ Assays of staurosporin ...
Electron Microscopic Observations on the Excretion of Cell
... the bacterial surface and was presumably released into the medium. It was often observed that the bulged-out cell-wall region was associated with somesmall granules at the surface (PI. 2, fig. 3; P1. 3, figs 6, 7, 10). In some cases distinct granules were not observed, but instead a greater electron ...
... the bacterial surface and was presumably released into the medium. It was often observed that the bulged-out cell-wall region was associated with somesmall granules at the surface (PI. 2, fig. 3; P1. 3, figs 6, 7, 10). In some cases distinct granules were not observed, but instead a greater electron ...
Introduction to Cell fate and plasticity Introduction, fate maps
... Fig. 2. In Xenopus, the blastula constitutes a selfdifferentiating morphogenetic field, in which cells are able to communicate over long distances. When the blastula is bisected with a scalpel blade, identical twins can be obtained, provided that both fragments retain Spemann’s organizer tissue. Thu ...
... Fig. 2. In Xenopus, the blastula constitutes a selfdifferentiating morphogenetic field, in which cells are able to communicate over long distances. When the blastula is bisected with a scalpel blade, identical twins can be obtained, provided that both fragments retain Spemann’s organizer tissue. Thu ...
Geranylgeranylated Proteins are Involved in the Regulation of
... effects of various modulators of farnesylated and geranylgeranylated proteins were investigated in myeloma cells. Results: Depletion of geranylgeranylpyrophosphate inhibited myeloma cell proliferation through accumulation of cells in G1 phase of the cell cycle and loss of cells in S phase. In contra ...
... effects of various modulators of farnesylated and geranylgeranylated proteins were investigated in myeloma cells. Results: Depletion of geranylgeranylpyrophosphate inhibited myeloma cell proliferation through accumulation of cells in G1 phase of the cell cycle and loss of cells in S phase. In contra ...
studies on the intracellular digestive process in mammalian tissue
... the DNA-protein coacervates as a marker permitted a study of the various stages of the intracellular digestive process which will be described in this report. The role of the dense bodies in intracellular digestion is also demonstrated by labeling them with a different colloidal metal (saccharated i ...
... the DNA-protein coacervates as a marker permitted a study of the various stages of the intracellular digestive process which will be described in this report. The role of the dense bodies in intracellular digestion is also demonstrated by labeling them with a different colloidal metal (saccharated i ...
Nuclear-cytoplasmic distribution of Inh2
... processes, including the cell cycle, gene expression, cell adhesion and glycogen metabolism (Cohen, 1989; Shenolikar, 1994). To achieve this wide range of effects, PP1 exists as a series of holoenzymes, with its catalytic subunit, PP1C, bound to a regulatory subunit, of which there are dozens. Evide ...
... processes, including the cell cycle, gene expression, cell adhesion and glycogen metabolism (Cohen, 1989; Shenolikar, 1994). To achieve this wide range of effects, PP1 exists as a series of holoenzymes, with its catalytic subunit, PP1C, bound to a regulatory subunit, of which there are dozens. Evide ...
Development of bacterial oxidative stress assays
... upregulating the production of reactive oxygen species. Reactive oxygen species are also produced by host immune cells as protection against infectious bacteria. Superoxide dismutase (SOD) is a defensive enzyme that protects bacteria from the damage caused by reactive oxygen species. It is hypothesi ...
... upregulating the production of reactive oxygen species. Reactive oxygen species are also produced by host immune cells as protection against infectious bacteria. Superoxide dismutase (SOD) is a defensive enzyme that protects bacteria from the damage caused by reactive oxygen species. It is hypothesi ...
Nance et al gastrulation paper - The Hardin Lab
... early embryo must establish an outer-inner polarity. Cells on the ventral surface of the embryo become committed to endodermal and mesodermal fates through a combination of cell signaling events and asymmetrically localized factors (Bowerman et al., 1993; Bowerman et al., 1992; Goldstein, ...
... early embryo must establish an outer-inner polarity. Cells on the ventral surface of the embryo become committed to endodermal and mesodermal fates through a combination of cell signaling events and asymmetrically localized factors (Bowerman et al., 1993; Bowerman et al., 1992; Goldstein, ...
Gene nuc2 - The Journal of Cell Biology
... We found that, among 587 strains, only one ts mutant designated nuc2-663 (nuc; nuclear structure alteration) showed a high frequency (80-90%) of condensed chromosomes in the arrested cells (Fig. 1 b). These chromosomes do not separate even after prolonged incubation. The frequency of condensed chrom ...
... We found that, among 587 strains, only one ts mutant designated nuc2-663 (nuc; nuclear structure alteration) showed a high frequency (80-90%) of condensed chromosomes in the arrested cells (Fig. 1 b). These chromosomes do not separate even after prolonged incubation. The frequency of condensed chrom ...
Chapter 6 A Tour of the Cell Multiple-Choice Questions
... A) plant cells are capable of having a much higher surface-to-volume ratio than animal cells. B) plant cells have a much more highly convoluted (folded) plasma membrane than animal cells. C) plant cells contain a large vacuole that reduces the volume of the cytoplasm. D) animal cells are more spheri ...
... A) plant cells are capable of having a much higher surface-to-volume ratio than animal cells. B) plant cells have a much more highly convoluted (folded) plasma membrane than animal cells. C) plant cells contain a large vacuole that reduces the volume of the cytoplasm. D) animal cells are more spheri ...
Nature - Andreas Jenny`s Laboratory
... neurulation by promoting the convergence of neural progenitors to the midline2–8. Here we show a novel role for PCP signalling during neurulation in zebrafish. We demonstrate that noncanonical Wnt/PCP signalling polarizes neural progenitors along the anteroposterior axis. This polarity is transientl ...
... neurulation by promoting the convergence of neural progenitors to the midline2–8. Here we show a novel role for PCP signalling during neurulation in zebrafish. We demonstrate that noncanonical Wnt/PCP signalling polarizes neural progenitors along the anteroposterior axis. This polarity is transientl ...
Molecular signatures of T-cell inhibition in HIV-1 infection
... TIM-1 through TIM-8 exist in mice, whereas humans express only TIM-1, TIM-3, and TIM-4 [41,42]. The TIM family members all have certain structural morphologies in common, i.e. an N-terminal immunoglobulin V domain, a mucin domain, and a transmembrane domain followed by a cytoplasmic tail [41-43]. TI ...
... TIM-1 through TIM-8 exist in mice, whereas humans express only TIM-1, TIM-3, and TIM-4 [41,42]. The TIM family members all have certain structural morphologies in common, i.e. an N-terminal immunoglobulin V domain, a mucin domain, and a transmembrane domain followed by a cytoplasmic tail [41-43]. TI ...
Document
... this type of media. SFM could also be very specific to certain cell types at certain growth phase hence the need to have very selective media leading to increased cost. Co mparison of price between SFM and SSM could be very subjective. For instance, use of SFM in research lab where volu me is not th ...
... this type of media. SFM could also be very specific to certain cell types at certain growth phase hence the need to have very selective media leading to increased cost. Co mparison of price between SFM and SSM could be very subjective. For instance, use of SFM in research lab where volu me is not th ...
Embryonic Stem Cells: from Blastocyst to in vitro Differentiation
... Another limiting factor relating to cell culture systems is that hES cells still require the presence of feeder layer. In fact, feeder-free system for hES cell culture is required if hES cell cultures are to become clinical-grade, since the use of animal feeders and/or ingredients for growth of hES ...
... Another limiting factor relating to cell culture systems is that hES cells still require the presence of feeder layer. In fact, feeder-free system for hES cell culture is required if hES cell cultures are to become clinical-grade, since the use of animal feeders and/or ingredients for growth of hES ...
Tissue engineering
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.