Approach to the interpretation of endometrial biopsies and curettings
... the normal gland to stroma ratio is maintained or there is slight increase. The endometrium shows proliferative activity, with cystically dilated glands of irregular sizes and shapes. Some glands may exhibit “out‐pouchings”, “infoldings” and “budding”. There is no nuclear atypia, the nuclei being ov ...
... the normal gland to stroma ratio is maintained or there is slight increase. The endometrium shows proliferative activity, with cystically dilated glands of irregular sizes and shapes. Some glands may exhibit “out‐pouchings”, “infoldings” and “budding”. There is no nuclear atypia, the nuclei being ov ...
Lysosomal enzymes and inflammation
... which were visible only with the electron microscope. These were first called 'the microsomes' (now known to be fragments of the endoplasmic reticulum and ...
... which were visible only with the electron microscope. These were first called 'the microsomes' (now known to be fragments of the endoplasmic reticulum and ...
Beyond apoptosis: nonapoptotic cell death in physiology and disease
... and Quest 2004) indicates that traditional apoptotic pathways may lead to necrotic cell death under certain conditions, and that specific mechanisms regulate this transition, as will be discussed. In this context, it is important to mention that such forms of regulated necrotic cell death have been ...
... and Quest 2004) indicates that traditional apoptotic pathways may lead to necrotic cell death under certain conditions, and that specific mechanisms regulate this transition, as will be discussed. In this context, it is important to mention that such forms of regulated necrotic cell death have been ...
JOHN MASON PAWELEK, Ph
... “The pathology of melanoma progression: Cell fusion as an explanation.” Linköping University, explanation. Linköping, Sweden, 3 October 2007. “Cancer cell fusion with migratory bone marrow-derived cells: A unifying explanation for metastasis 1st Conference on cell fusion and cancer”, Söderköping, Sw ...
... “The pathology of melanoma progression: Cell fusion as an explanation.” Linköping University, explanation. Linköping, Sweden, 3 October 2007. “Cancer cell fusion with migratory bone marrow-derived cells: A unifying explanation for metastasis 1st Conference on cell fusion and cancer”, Söderköping, Sw ...
Shewanella oneidensis MR-1 chemotaxis proteins and electron
... proteins with the Cache domain (mcp_cache, SO_2240) or the PAS (Per/Arnt/Sim) domain (mcp_pas, SO_1385). In the present paper, we report studies of S. oneidensis MR-1 that lend some insight into how microbes in this group can ‘sense’ the presence of a solid substrate such as a mineral surface, and m ...
... proteins with the Cache domain (mcp_cache, SO_2240) or the PAS (Per/Arnt/Sim) domain (mcp_pas, SO_1385). In the present paper, we report studies of S. oneidensis MR-1 that lend some insight into how microbes in this group can ‘sense’ the presence of a solid substrate such as a mineral surface, and m ...
Urinalysis
... Rapidly multiply in urine standing at room temperature Should be interpreted in view of clinical symptoms. ...
... Rapidly multiply in urine standing at room temperature Should be interpreted in view of clinical symptoms. ...
Induction of somatic embryogenesis as an example of stress
... efficient in this respect, we may get closer to understanding the processes underlying the induction phase of SE”. In carrot SE 2,4-D is required for the initiation of a program that can proceed further on its own, while the removal of 2,4-D from the induction medium may be important to control the ...
... efficient in this respect, we may get closer to understanding the processes underlying the induction phase of SE”. In carrot SE 2,4-D is required for the initiation of a program that can proceed further on its own, while the removal of 2,4-D from the induction medium may be important to control the ...
Lysis of Human Monocytic Leukemia Cells by
... factor in the increased sensitivity to ATP-mediated lysis. The lysis in a 6-hour "Cr release assay, induced by 1.25 mmol/L ATP, of THP- 1 cells cultured with 1,000 U/mL of IFN-y or GM-CSF for the indicated length of time was assessed. IFN-y was able progressivelyto increase the sensitivity of THP- 1 ...
... factor in the increased sensitivity to ATP-mediated lysis. The lysis in a 6-hour "Cr release assay, induced by 1.25 mmol/L ATP, of THP- 1 cells cultured with 1,000 U/mL of IFN-y or GM-CSF for the indicated length of time was assessed. IFN-y was able progressivelyto increase the sensitivity of THP- 1 ...
Mesoderm migration in the Xenopus gastrula
... its adhesive properties, its more specific role in mesoderm migration is the induction of lamellipodium formation. In this way, the SCR substrate not only provides adhesiveness and resistance to mesoderm cell traction, but also regulates the protrusive activities of migrating cells. Migrating mesode ...
... its adhesive properties, its more specific role in mesoderm migration is the induction of lamellipodium formation. In this way, the SCR substrate not only provides adhesiveness and resistance to mesoderm cell traction, but also regulates the protrusive activities of migrating cells. Migrating mesode ...
Haematopoietic and immune defects associated with GATA2 mutation
... Fig 1. Role of GATA2 in haematopoietic differentiation. Simplified map of key interactions of GATA2 with selected major lineage-specifying transcription factors. The factors indicated are necessary for downstream differentiation according to knock-out models or are highly expressed in differentiated ...
... Fig 1. Role of GATA2 in haematopoietic differentiation. Simplified map of key interactions of GATA2 with selected major lineage-specifying transcription factors. The factors indicated are necessary for downstream differentiation according to knock-out models or are highly expressed in differentiated ...
localization of products of atp hydrolysis in mammalian smooth
... was incubated in medium in which the ATP was replaced by 0.09 M Na B glycerol phosphate. In addition to the primary experiment and its controls, we carried out ancillary experiments to assess, independently, the role of the various incubating conditions and media constituents. Mouse urinary bladder, ...
... was incubated in medium in which the ATP was replaced by 0.09 M Na B glycerol phosphate. In addition to the primary experiment and its controls, we carried out ancillary experiments to assess, independently, the role of the various incubating conditions and media constituents. Mouse urinary bladder, ...
Antiproliferative and apoptotic effects of O
... on proliferation and apoptosis in cultures of the human hepatoblastoma HepG2 and hepatocarcinoma HBG cell lines. Our results show that TRX decreased DNA synthesis in a time- and dose-dependent manner and with a higher efficiency than DFO. Mitotic index was also strongly decreased by TRX and, unexpec ...
... on proliferation and apoptosis in cultures of the human hepatoblastoma HepG2 and hepatocarcinoma HBG cell lines. Our results show that TRX decreased DNA synthesis in a time- and dose-dependent manner and with a higher efficiency than DFO. Mitotic index was also strongly decreased by TRX and, unexpec ...
Effect of Gibberellic Acid and Actinomycin D on the Formation and
... reported for aleurone cells of germinating grains (3) and isolated layers treated for various lengths of time with GA (1, 13, 15, 28). However, the specific sequence of events leading to synthesis and secretion of hydrolases has not been adequately established. This is partly due to the difficulty o ...
... reported for aleurone cells of germinating grains (3) and isolated layers treated for various lengths of time with GA (1, 13, 15, 28). However, the specific sequence of events leading to synthesis and secretion of hydrolases has not been adequately established. This is partly due to the difficulty o ...
Naive T cell homeostasis: from awareness of space to a
... were seeded at higher frequencies25. Interestingly, the transfer of TCR-transgenic CD4+ T cells at very low frequencies led to an increase (by modest proliferation) in the size of the donor CD4+ T cell pool. Together these findings strongly suggest that homeostasis of the naive T cell pool produces ...
... were seeded at higher frequencies25. Interestingly, the transfer of TCR-transgenic CD4+ T cells at very low frequencies led to an increase (by modest proliferation) in the size of the donor CD4+ T cell pool. Together these findings strongly suggest that homeostasis of the naive T cell pool produces ...
An antibody raised to a maize auxin-binding protein has inhibitory
... affected in its auxin-regulated division response. This suggests that plasma membrane proteins of abpl-type (or immunologically related to abpl), whose activation triggers early modifications of ionic exchanges and electrical properties, are somehow involved in the regulation of division in protopla ...
... affected in its auxin-regulated division response. This suggests that plasma membrane proteins of abpl-type (or immunologically related to abpl), whose activation triggers early modifications of ionic exchanges and electrical properties, are somehow involved in the regulation of division in protopla ...
Wilson, S. I., Graziano, E., Harland, R., Jessell, T. M., and - ICB-USP
... have been implicated in neural induction. The precise roles, if any, that these factors play in neural induction in amniotes remains to be established. Results: To monitor the initial steps of neural induction in the chick embryo, we developed an in vitro assay of neural differentiation in epiblast ...
... have been implicated in neural induction. The precise roles, if any, that these factors play in neural induction in amniotes remains to be established. Results: To monitor the initial steps of neural induction in the chick embryo, we developed an in vitro assay of neural differentiation in epiblast ...
Discreteness of chromosome territories
... is whether chromosomes are interwoven with one another at their periphery or whether they form mutually exclusive territories. Similarly, we might ask to what extent subdomains within chromosomes are interwoven. Some data related to this topic have been published previously. Images of interphase nuc ...
... is whether chromosomes are interwoven with one another at their periphery or whether they form mutually exclusive territories. Similarly, we might ask to what extent subdomains within chromosomes are interwoven. Some data related to this topic have been published previously. Images of interphase nuc ...
Protection of Retinal Ganglion Cells from Natural and Axotomy
... 1990). It has been demonstrated that at birth the ganglion cell layer of the rat retina is constituted almost entirely of ganglion cells (Perry et al., 1983; Rabacchi et al., 1994a). As the retina matures, an increasing proportion of the neurons in this layer is represented by amacrine cells, which ...
... 1990). It has been demonstrated that at birth the ganglion cell layer of the rat retina is constituted almost entirely of ganglion cells (Perry et al., 1983; Rabacchi et al., 1994a). As the retina matures, an increasing proportion of the neurons in this layer is represented by amacrine cells, which ...
The Involvement of the Fibronectin Type II-like Modules
... acid, pH 6.0 (28). After extensive rinses, cellular stain was dissolved in 10% acetic acid, and cell numbers were quantitated by measurement of the optical density at 590 nm in a microplate reader. Positive control wells were coated with fibronectin (Chemicon) or acid soluble type I collagen prepare ...
... acid, pH 6.0 (28). After extensive rinses, cellular stain was dissolved in 10% acetic acid, and cell numbers were quantitated by measurement of the optical density at 590 nm in a microplate reader. Positive control wells were coated with fibronectin (Chemicon) or acid soluble type I collagen prepare ...
Pluripotent Stem Cell Handbook
... Human ESCs (hESCs) are isolated from the inner cell mass of the blastocyst stage of a developing embryo and were first derived in 1998 by Dr. James Thomson at the University of Wisconsin, Madison1. iPSCs are generated via ectopic expression of one or more genes to reprogram an adult somatic cell. Th ...
... Human ESCs (hESCs) are isolated from the inner cell mass of the blastocyst stage of a developing embryo and were first derived in 1998 by Dr. James Thomson at the University of Wisconsin, Madison1. iPSCs are generated via ectopic expression of one or more genes to reprogram an adult somatic cell. Th ...
Cell growth and differentiation in Arabidopsis
... this process, cell wall components are transported to and integrated in the tip area via the cytoskeleton, where high rates of both exocytosis and endocytosis are reported (Ueda et al., 2004; Ovecka et al., 2005; Smith and Oppenheimer, 2005). Actin has been shown to be an integral component of the m ...
... this process, cell wall components are transported to and integrated in the tip area via the cytoskeleton, where high rates of both exocytosis and endocytosis are reported (Ueda et al., 2004; Ovecka et al., 2005; Smith and Oppenheimer, 2005). Actin has been shown to be an integral component of the m ...
The Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and
... Analysis of Mitochondrial Ribosomes and Polysomes—For the analysis of mitochondrial polysomes, cells were labeled with [35S]methionine as described (5) and mixed with 143B.TK⫺ cells that had been labeled for 1 day with [5-3H]uridine in the absence of inhibitors (to provide size markers for the sucro ...
... Analysis of Mitochondrial Ribosomes and Polysomes—For the analysis of mitochondrial polysomes, cells were labeled with [35S]methionine as described (5) and mixed with 143B.TK⫺ cells that had been labeled for 1 day with [5-3H]uridine in the absence of inhibitors (to provide size markers for the sucro ...
Entry of oomycete and fungal effectors into plant and animal host cells
... generally effective, as most fungal pathogens of animals are opportunistic, causing disease mainly on immunecompromised hosts (Romani, 2011). Effector proteins of plant and animal pathogens A major weapon used against plant and animal immunity machinery by cellular pathogens, including bacteria, fun ...
... generally effective, as most fungal pathogens of animals are opportunistic, causing disease mainly on immunecompromised hosts (Romani, 2011). Effector proteins of plant and animal pathogens A major weapon used against plant and animal immunity machinery by cellular pathogens, including bacteria, fun ...
localization of products of atp hydrolysis in
... changes in the protocol, a set of ancillary experiments was performed in which one factor was varied while the others were held constant at the values of the primary experiment. While these data do not aid in a comparison of the findings with those obtained with the unmodified procedure of Wachstein ...
... changes in the protocol, a set of ancillary experiments was performed in which one factor was varied while the others were held constant at the values of the primary experiment. While these data do not aid in a comparison of the findings with those obtained with the unmodified procedure of Wachstein ...
Expression of the RET Receptor Tyrosine Kinase and GDNFR
... EMATOPOIESIS IS A tightly regulated process in which a small population of self-renewing primitive progenitors generates an offspring of increasingly differentiated end cells with specific functional activities.1 This process is controlled by a number of growth factors and cytokines,1 with some of t ...
... EMATOPOIESIS IS A tightly regulated process in which a small population of self-renewing primitive progenitors generates an offspring of increasingly differentiated end cells with specific functional activities.1 This process is controlled by a number of growth factors and cytokines,1 with some of t ...
Tissue engineering
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.