Making a firm decision: multifaceted regulation of cell fate in the
... embryo41–43. Members of the Par complex, including jAM1 (ReF. 42), aPKC and PAR3 (ReF. 41), become local‑ ized apically at the 8‑cell stage, whereas PAR1 is localized in basolateral regions43. When cells divide asymmetrically the outer daughters retain this polarity, but inside ones inherit mainly t ...
... embryo41–43. Members of the Par complex, including jAM1 (ReF. 42), aPKC and PAR3 (ReF. 41), become local‑ ized apically at the 8‑cell stage, whereas PAR1 is localized in basolateral regions43. When cells divide asymmetrically the outer daughters retain this polarity, but inside ones inherit mainly t ...
Summer 2012
... bioluminescence, the emission of light produced by a living organism. Luciferases are highly prized bioindicators for life science research and drug discovery, owing to their remarkable sensitivity, lack of toxicity and wide dynamic range of quantitation. Luciferases are used for many bioluminescenc ...
... bioluminescence, the emission of light produced by a living organism. Luciferases are highly prized bioindicators for life science research and drug discovery, owing to their remarkable sensitivity, lack of toxicity and wide dynamic range of quantitation. Luciferases are used for many bioluminescenc ...
The Induction of 72-kD Gelatinase in T Cells upon Adhesion to
... brain parenchyma and delayed the onset of EAE. These studies strongly suggest that the VLA-4 integrin is an important determinant for T cell entry into the central nervous system (CNS) leading to the development of EAE. The mechanisms by which T cells actively invade the perivascular tissue are virt ...
... brain parenchyma and delayed the onset of EAE. These studies strongly suggest that the VLA-4 integrin is an important determinant for T cell entry into the central nervous system (CNS) leading to the development of EAE. The mechanisms by which T cells actively invade the perivascular tissue are virt ...
Proteolysis and orientation in Dictyostelium slugs
... soaked up by the polyacrylamide beads and applied to the tips of migrating slugs in the same manner as with papain above. If a mixture of five different water-soluble inhibitors was used the slugs bent around the bead; clearly the inhibitors were slowing the cells on the side to which were applied ( ...
... soaked up by the polyacrylamide beads and applied to the tips of migrating slugs in the same manner as with papain above. If a mixture of five different water-soluble inhibitors was used the slugs bent around the bead; clearly the inhibitors were slowing the cells on the side to which were applied ( ...
Ocular Surface Disorders - Current Concepts and Management
... silicone provides adequate oxygen transmission for continuous wear, however Omafilcon A (proclear), a novel biomimetic, 59 % water content hydrogel soft contact lenses for daily wear has been found to give better comfort. 3. Promotion of epithelial wound healing and differentiation (a) Topical autol ...
... silicone provides adequate oxygen transmission for continuous wear, however Omafilcon A (proclear), a novel biomimetic, 59 % water content hydrogel soft contact lenses for daily wear has been found to give better comfort. 3. Promotion of epithelial wound healing and differentiation (a) Topical autol ...
hTERT Inhibition Triggers Epstein–Barr Virus Lytic Cycle and
... and several histone deacetylase inhibitors (9–12). EBVcarrying tumor cells may also be killed by prodrugs, such as ganciclovir or radiolabeled nucleoside analogs, which are activated by EBV lytic proteins, such as the viral thymidine kinase (9, 13, 14). Notably, combined treatment with arginine buty ...
... and several histone deacetylase inhibitors (9–12). EBVcarrying tumor cells may also be killed by prodrugs, such as ganciclovir or radiolabeled nucleoside analogs, which are activated by EBV lytic proteins, such as the viral thymidine kinase (9, 13, 14). Notably, combined treatment with arginine buty ...
1 - Global Health Laboratories
... numbers is unlikely to be causing disease. If both are present at over 100 colonies, sub-culture both organisms. If more than two organisms are isolated, then do not sub-culture / identify any of them since this is highly likely to be a contaminated specimen. An exception is that all growth from a s ...
... numbers is unlikely to be causing disease. If both are present at over 100 colonies, sub-culture both organisms. If more than two organisms are isolated, then do not sub-culture / identify any of them since this is highly likely to be a contaminated specimen. An exception is that all growth from a s ...
![An FGF4-FRS2[alpha]-Cdx2 Axis in Trophoblast Stem Cells Induces](http://s1.studyres.com/store/data/004612399_1-b568e9f7ef7ac5f7304ea5d975b0dd52-300x300.png)
An FGF4-FRS2[alpha]-Cdx2 Axis in Trophoblast Stem Cells Induces
... There is an increasing interest in stem cells as potential therapeutic reagents for various degenerative diseases and damaged organs. In fact, a variety of multipotent stem cells have recently been discovered in many tissues and organs and much effort has been made to manipulate them in vitro by usi ...
... There is an increasing interest in stem cells as potential therapeutic reagents for various degenerative diseases and damaged organs. In fact, a variety of multipotent stem cells have recently been discovered in many tissues and organs and much effort has been made to manipulate them in vitro by usi ...
A role for the DNA-damage checkpoint kinase Chk1 in the virulence
... Developmental decisions often involve differentiation processes that need to reset the cell cycle for induction of a new morphogenetic program. This is probably also the case for induction of the virulence program in pathogenic fungi. It could therefore be assumed that in pathogenic fungi the contro ...
... Developmental decisions often involve differentiation processes that need to reset the cell cycle for induction of a new morphogenetic program. This is probably also the case for induction of the virulence program in pathogenic fungi. It could therefore be assumed that in pathogenic fungi the contro ...
Measuring the mechanical properties of plant cells by combining
... Several models have been proposed that describe indentation experiments at different scales. A mathematical model that is often used to interpret data from AFM experiments is the Hertz model (Lin et al., 2007). This assumes that indentations are small enough to only probe elastic properties of the ...
... Several models have been proposed that describe indentation experiments at different scales. A mathematical model that is often used to interpret data from AFM experiments is the Hertz model (Lin et al., 2007). This assumes that indentations are small enough to only probe elastic properties of the ...
Regeneration and the need for simpler model organisms
... has, in fact, been shown during salamander limb regeneration for the retinoic acid nuclear receptor and FGF pathways (Boilly et al. 1991; Mullen et al. 1996; Pecorino et al. 1996). However, if regeneration merely uses developmental pathways, why should we be bothered with its study? The answer is si ...
... has, in fact, been shown during salamander limb regeneration for the retinoic acid nuclear receptor and FGF pathways (Boilly et al. 1991; Mullen et al. 1996; Pecorino et al. 1996). However, if regeneration merely uses developmental pathways, why should we be bothered with its study? The answer is si ...
The allocation of early blastomeres to the ectoderm and endoderm
... tiers called ‘veg1’ and ‘veg2’ (Fig. 1B,C). In vitro cell aggregation experiments have shown that both veg1 and veg2 cells possess the ability to make endoderm (Khaner and Wilt, 1991), but earlier fate-mapping studies projected that only the veg2 tier makes the archenteron in the intact embryo (Hörs ...
... tiers called ‘veg1’ and ‘veg2’ (Fig. 1B,C). In vitro cell aggregation experiments have shown that both veg1 and veg2 cells possess the ability to make endoderm (Khaner and Wilt, 1991), but earlier fate-mapping studies projected that only the veg2 tier makes the archenteron in the intact embryo (Hörs ...
necessary amino acids and vitamins
... Most experiments were performed with a strain of human embryonic diploid lung fibroblasts (HEDLF) cells isolated in this laboratory and referred to as the ' S' strain. These cells were frozen after approximately 15 population divisions and stored in liquid nitrogen. They show human diploid karyology ...
... Most experiments were performed with a strain of human embryonic diploid lung fibroblasts (HEDLF) cells isolated in this laboratory and referred to as the ' S' strain. These cells were frozen after approximately 15 population divisions and stored in liquid nitrogen. They show human diploid karyology ...
The effects of extracellular pH on immune function
... many of the functional changes in neutrophils and other immune cells. Others have discovered a direct relationship between intracellular and extracellular pH, regardless of which milieu is altered experimentally [30, 31]. For example, Osaki et al. [30] found that initial, extracellular alkalinizatio ...
... many of the functional changes in neutrophils and other immune cells. Others have discovered a direct relationship between intracellular and extracellular pH, regardless of which milieu is altered experimentally [30, 31]. For example, Osaki et al. [30] found that initial, extracellular alkalinizatio ...
Mutational analysis supports a core role for Drosophila a
... a-catenin associates the cadherin–catenin complex with the actin cytoskeleton. a-catenin binds to b-catenin, which links it to the cadherin cytoplasmic tail, and F-actin, but also to a multitude of actin-associated proteins. These interactions suggest a highly complex cadherin–actin interface. Moreo ...
... a-catenin associates the cadherin–catenin complex with the actin cytoskeleton. a-catenin binds to b-catenin, which links it to the cadherin cytoplasmic tail, and F-actin, but also to a multitude of actin-associated proteins. These interactions suggest a highly complex cadherin–actin interface. Moreo ...
Concepts of Biology
... The microscopes we use today are far more complex than those used in the 1600s by Antony van Leeuwenhoek, a Dutch shopkeeper who had great skill in crafting lenses. Despite the limitations of his now-ancient lenses, van Leeuwenhoek observed the movements of protists (a type of single-celled organism ...
... The microscopes we use today are far more complex than those used in the 1600s by Antony van Leeuwenhoek, a Dutch shopkeeper who had great skill in crafting lenses. Despite the limitations of his now-ancient lenses, van Leeuwenhoek observed the movements of protists (a type of single-celled organism ...
Research Template - UMKC School of Medicine
... The adventitia consists of an extracellular scaffold containing fibroblasts, blood and lymphatic vessels, nerves, progenitor and immune cells This makes the adventitia the most complex compartment of the blood vessel wall Recent published data shows that the adventitia is a center for storage, in ...
... The adventitia consists of an extracellular scaffold containing fibroblasts, blood and lymphatic vessels, nerves, progenitor and immune cells This makes the adventitia the most complex compartment of the blood vessel wall Recent published data shows that the adventitia is a center for storage, in ...
Lipid defense response of Chlorella as theoretical background in
... composition of it: by increase in rigidity and the lipid quantity of it cell wall and plasmalemma. Laboratory studies have shown that there are two active absorbing substances in Chlorella – sporopolein and alga cell wall [3,4]. The cell wall of Chlorella have three layers, of which the thicker midd ...
... composition of it: by increase in rigidity and the lipid quantity of it cell wall and plasmalemma. Laboratory studies have shown that there are two active absorbing substances in Chlorella – sporopolein and alga cell wall [3,4]. The cell wall of Chlorella have three layers, of which the thicker midd ...
Overexpression of vinculin suppresses cell motility in BALB/c 3T3 cells
... equivalent to the intrinsic protein of 3T3 cells: (1) immunofluorescence studies have shown that the transfected vinculin is co-distributed in adhesion plaques with the endogenous vinculin; (2) chicken and mammalian vinculins, both human [Price et al., 1989; Weller et al., 19901 and partial sequence ...
... equivalent to the intrinsic protein of 3T3 cells: (1) immunofluorescence studies have shown that the transfected vinculin is co-distributed in adhesion plaques with the endogenous vinculin; (2) chicken and mammalian vinculins, both human [Price et al., 1989; Weller et al., 19901 and partial sequence ...
The Dielectric Response of Spherical Live Cells in Suspension: An
... at the membrane’s surfaces. For spherical cells suspended in aqueous solutions, we give an analytic solution for the dielectric function, which is shown to account for the a- and b-plateaus seen in many experimental data. The effect of different physical parameters on the dielectric curves is method ...
... at the membrane’s surfaces. For spherical cells suspended in aqueous solutions, we give an analytic solution for the dielectric function, which is shown to account for the a- and b-plateaus seen in many experimental data. The effect of different physical parameters on the dielectric curves is method ...
A matter of size: developmental control of organ size in plants
... for auxin signaling in cell expansion has been confirmed by recent studies of the AUXIN-BINDING PROTEIN1 (ABP1) gene. Ectopic expression of ABP1 in transgenic tobacco leaves led to remarkable increases in cell volume. However, ABP1 does not seem to control organ size because the increase in cell siz ...
... for auxin signaling in cell expansion has been confirmed by recent studies of the AUXIN-BINDING PROTEIN1 (ABP1) gene. Ectopic expression of ABP1 in transgenic tobacco leaves led to remarkable increases in cell volume. However, ABP1 does not seem to control organ size because the increase in cell siz ...
Chapter 7 Cellular Structure and Function HUMAN SKIN HUMAN
... endosymbiont theory, a symbiotic mutual rela–tionship involved one prokaryotic cell living inside of another. The endosymbiont theory is discussed in greater detail in Chapter 14. Imagine how organisms would be different if the eukaryotic form had not evolved. Because eukaryotic cells are larger and ...
... endosymbiont theory, a symbiotic mutual rela–tionship involved one prokaryotic cell living inside of another. The endosymbiont theory is discussed in greater detail in Chapter 14. Imagine how organisms would be different if the eukaryotic form had not evolved. Because eukaryotic cells are larger and ...
Hallmarks of epithelial to mesenchymal transition are detectable in
... fact that anti-inflammatory strategies, such as anti-TNF antibodies or immunosuppressive medications, are not effective in preventing fibrosis and that no specific anti-fibrotic medical therapy exists [4]. Current hypothesis suggests that the first step of intestinal fibrosis is a tissue damage caus ...
... fact that anti-inflammatory strategies, such as anti-TNF antibodies or immunosuppressive medications, are not effective in preventing fibrosis and that no specific anti-fibrotic medical therapy exists [4]. Current hypothesis suggests that the first step of intestinal fibrosis is a tissue damage caus ...
Middle East Jeopardy - Central Kitsap Junior High
... Transports material throughout the cell. Endoplasmic Reticulum ...
... Transports material throughout the cell. Endoplasmic Reticulum ...
The cellular and molecular basis of cnidarian neurogenesis
... homeostasis of the nervous system. The generation of nerve cells has been analyzed in detail in few bilaterian model organisms, leaving open many questions about the evolution of this process. As the sister group to bilaterians, cnidarians occupy an informative phylogenetic position to address the e ...
... homeostasis of the nervous system. The generation of nerve cells has been analyzed in detail in few bilaterian model organisms, leaving open many questions about the evolution of this process. As the sister group to bilaterians, cnidarians occupy an informative phylogenetic position to address the e ...
Tissue engineering
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.