Staphylococcus aureus-induced G2/M phase transition delay
... proportion of cells in the G1/G0 phase. [14]. Exposure of eukaryotic cells to the cytolethal distending toxin of E. coli results in arrest in both the G1 and G2 phases [12,15]. Pathogen-induced cell cycle alteration may be linked to the inhibition of cyclindependent kinases (CDKs), key effectors res ...
... proportion of cells in the G1/G0 phase. [14]. Exposure of eukaryotic cells to the cytolethal distending toxin of E. coli results in arrest in both the G1 and G2 phases [12,15]. Pathogen-induced cell cycle alteration may be linked to the inhibition of cyclindependent kinases (CDKs), key effectors res ...
Lesson Overview
... - Some of the proteins form channels and pumps that help to move material across the cell membrane - Many of the carbohydrate molecules act like chemical identification cards, allowing individual cells to identify one another ...
... - Some of the proteins form channels and pumps that help to move material across the cell membrane - Many of the carbohydrate molecules act like chemical identification cards, allowing individual cells to identify one another ...
Developmental plasticity, cell fate specification and morphogenesis
... and ICM identities are incompatible with each other and indeed Cdx2 and Oct4 reciprocally inhibit each other [41]. One of the important functions of the TE is the formation of the blastocyst cavity, the location of which determines the embryonic –abembryonic axis of the embryo. As the TE matures, it ...
... and ICM identities are incompatible with each other and indeed Cdx2 and Oct4 reciprocally inhibit each other [41]. One of the important functions of the TE is the formation of the blastocyst cavity, the location of which determines the embryonic –abembryonic axis of the embryo. As the TE matures, it ...
Flyer AN07 VDAC.cdr
... carcinoma cells VDAC is highly expressed and can form a complex with hexokinase and Bcl2 proteins making the cell resistant towards chemotherapeutic agents by supporting anti-apoptotic behaviour. By blocking VDAC function with erastin, cancer cells can be destroyed selectively. VDAC structure has be ...
... carcinoma cells VDAC is highly expressed and can form a complex with hexokinase and Bcl2 proteins making the cell resistant towards chemotherapeutic agents by supporting anti-apoptotic behaviour. By blocking VDAC function with erastin, cancer cells can be destroyed selectively. VDAC structure has be ...
10 m
... An example of an internal signal occurs at the M phase checkpoint In this case, anaphase does not begin if any kinetochores remain unattached to spindle microtubules Attachment of all of the kinetochores activates a regulatory complex, which then activates the enzyme separase Separase allow ...
... An example of an internal signal occurs at the M phase checkpoint In this case, anaphase does not begin if any kinetochores remain unattached to spindle microtubules Attachment of all of the kinetochores activates a regulatory complex, which then activates the enzyme separase Separase allow ...
Abstract
... An electron transfer flavoprotein (ETF) is essential for viability and its depletion causes a ...
... An electron transfer flavoprotein (ETF) is essential for viability and its depletion causes a ...
Embryonic stem cells in non-human primates An overview of neural
... tissues. ES cell lines have been derived from several NHP species. The first lines were isolated in the Rhesus monkey (Macaca mulatta) in 1995 by Dr. James Thomson at the Wisconsin National Primate Research Center (Thomson et al., 1995), and few years later in the cynomolgus monkey (Macaca fascicula ...
... tissues. ES cell lines have been derived from several NHP species. The first lines were isolated in the Rhesus monkey (Macaca mulatta) in 1995 by Dr. James Thomson at the Wisconsin National Primate Research Center (Thomson et al., 1995), and few years later in the cynomolgus monkey (Macaca fascicula ...
IL-10 transcription is negatively regulated by BAF180, a component
... SNF2-like ATPase subunits, and these ATPases couple the hydrolysis of ATP to changes in chromatin structure. SWI/SNF, Mi2, ISWI, and other ATP-dependent remodeling enzymes are classified into subfamilies based upon homology of the ATPase subunit [4,19,20]. These remodeling enzymes appear to both act ...
... SNF2-like ATPase subunits, and these ATPases couple the hydrolysis of ATP to changes in chromatin structure. SWI/SNF, Mi2, ISWI, and other ATP-dependent remodeling enzymes are classified into subfamilies based upon homology of the ATPase subunit [4,19,20]. These remodeling enzymes appear to both act ...
reviews - London Health Sciences Centre
... shedding of cells from a primary tumour into the circulation, survival of the cells in the circulation, arrest in a new organ, extravasation into the surrounding tissue, initiation and maintenance of growth, and vascularization of the metastatic tumour. • Some types of tumour show an organ-specific ...
... shedding of cells from a primary tumour into the circulation, survival of the cells in the circulation, arrest in a new organ, extravasation into the surrounding tissue, initiation and maintenance of growth, and vascularization of the metastatic tumour. • Some types of tumour show an organ-specific ...
Genetic transformation of HeLa cells by Agrobacterium - igem
... different mechanisms may be responsible for transformation of HeLa cells by Agrobacterium: vir dependent and vir independent. Next, we examined the ability of Agrobacterium to infect other human cell lines. Table 1 shows that HEK393 cells and neuronal PC12 cells also were susceptible to genetic tran ...
... different mechanisms may be responsible for transformation of HeLa cells by Agrobacterium: vir dependent and vir independent. Next, we examined the ability of Agrobacterium to infect other human cell lines. Table 1 shows that HEK393 cells and neuronal PC12 cells also were susceptible to genetic tran ...
performance of nonlinear visual units in ocular hypertension
... packages. Examination of the threshold data from each subject to a principal component obtained from both methods showed that the analysis. The first two principal components measured variances were heterogeneous and were indeed primarily correlated and composed that a log transform was indicated fo ...
... packages. Examination of the threshold data from each subject to a principal component obtained from both methods showed that the analysis. The first two principal components measured variances were heterogeneous and were indeed primarily correlated and composed that a log transform was indicated fo ...
Chewing the fat on natural killer T cell development
... Figure 1. CD1d is initially expressed on the cell surface loaded with phospholipids but then traffics to lysosomes where phospholipids are exchanged with glycolipids. (A) In normal cells, lysosomal glycolipid degradation, which is controlled by various hydrolytic enzymes and lipid transfer proteins, ...
... Figure 1. CD1d is initially expressed on the cell surface loaded with phospholipids but then traffics to lysosomes where phospholipids are exchanged with glycolipids. (A) In normal cells, lysosomal glycolipid degradation, which is controlled by various hydrolytic enzymes and lipid transfer proteins, ...
The Transition Between Different Physiological States
... increase in DNA and a second, but smaller, burst of synthesis. In the temperature shift, which involves no overt change in the definitive size and composition of the cells, the rate of DNA synthesis thus cycles between extremely high and low values before the final 37' rate is established. On the ba ...
... increase in DNA and a second, but smaller, burst of synthesis. In the temperature shift, which involves no overt change in the definitive size and composition of the cells, the rate of DNA synthesis thus cycles between extremely high and low values before the final 37' rate is established. On the ba ...
Chapter 1: The Microbial World and You
... The smaller the distance between objects at which they can be distinguished as separate, the greater the resolving power. Light must pass between two objects in order for them to be seen as separate. Depends on light wavelength. If wavelength is too long to pass between objects, they will appe ...
... The smaller the distance between objects at which they can be distinguished as separate, the greater the resolving power. Light must pass between two objects in order for them to be seen as separate. Depends on light wavelength. If wavelength is too long to pass between objects, they will appe ...
Regulated appearance of NMDA receptor subunits and channel
... nervous system are not available for molecular analyses, one-cell-derived neuroectodermal progenitor cell lines can provide appropriate in vitro models to understand the importance of the subunit composition of NMDA receptors and to investigate the time schedule of the subunit expression during some ...
... nervous system are not available for molecular analyses, one-cell-derived neuroectodermal progenitor cell lines can provide appropriate in vitro models to understand the importance of the subunit composition of NMDA receptors and to investigate the time schedule of the subunit expression during some ...
(Vibrcgen-Zellmiihle, Fa. E. Buhl er, Tiibingen, Germany). The results
... though initial selection was for lactose growth. Two of there were crossed (211-L5-a Y 341-&A ) ond an isolate designated 41 I-L5-A was obtained. This isolate her been used for all rubrequent glycerol growth studier. Grwth conditions ore: rotary shaking, 3/4 inch TO d ’tvs, 150 cycles per minute, 30 ...
... though initial selection was for lactose growth. Two of there were crossed (211-L5-a Y 341-&A ) ond an isolate designated 41 I-L5-A was obtained. This isolate her been used for all rubrequent glycerol growth studier. Grwth conditions ore: rotary shaking, 3/4 inch TO d ’tvs, 150 cycles per minute, 30 ...
Document
... they are involved in calcium signaling and intermediary metabolism, and they regulate the extrinsic apoptotic pathway following cell insult. Recent studies show that mitochondria are implicated in many diseases including neurological disorders such as Parkinson’s1 and Alzheimer’s disease2, as well a ...
... they are involved in calcium signaling and intermediary metabolism, and they regulate the extrinsic apoptotic pathway following cell insult. Recent studies show that mitochondria are implicated in many diseases including neurological disorders such as Parkinson’s1 and Alzheimer’s disease2, as well a ...
Lysosomal Sequestration of Polyamine
... trials—despite accumulating ~5 times more analogue than parental cells. We now report that treatment of CHO/664 cells with DENSPM results in the formation of numerous large cytoplasmic vacuoles, which on the basis of electron microscopy and cytochemical staining seem to be lysosomal in origin. A s ...
... trials—despite accumulating ~5 times more analogue than parental cells. We now report that treatment of CHO/664 cells with DENSPM results in the formation of numerous large cytoplasmic vacuoles, which on the basis of electron microscopy and cytochemical staining seem to be lysosomal in origin. A s ...
Document
... An example of an internal signal occurs at the M phase checkpoint In this case, anaphase does not begin if any kinetochores remain unattached to spindle microtubules Attachment of all of the kinetochores activates a regulatory complex, which then activates the enzyme separase Separase allow ...
... An example of an internal signal occurs at the M phase checkpoint In this case, anaphase does not begin if any kinetochores remain unattached to spindle microtubules Attachment of all of the kinetochores activates a regulatory complex, which then activates the enzyme separase Separase allow ...
Contract Monoclonal Antibody Production
... bioreactors). For cost, speed and scale up reasons, the in vivo type has been the most popular method of choice. Custom in vivo monoclonal antibody production is accomplished using a wide variety of cell lines. At Scantibodies BALB/c mice are maintained in a breeding colony with a population of 100, ...
... bioreactors). For cost, speed and scale up reasons, the in vivo type has been the most popular method of choice. Custom in vivo monoclonal antibody production is accomplished using a wide variety of cell lines. At Scantibodies BALB/c mice are maintained in a breeding colony with a population of 100, ...
Choose your fate: artery, vein or lymphatic vessel?
... initiates Prox1 expression in those progenitors remains elusive. Prox1 activity is necessary and sufficient to promote lymphatic endothelial fate in otherwise blood vascular endothelial cells [39]. VEGF-C, which regulates lymphatic endothelial cell proliferation via its association with VEGFR-3 [40– ...
... initiates Prox1 expression in those progenitors remains elusive. Prox1 activity is necessary and sufficient to promote lymphatic endothelial fate in otherwise blood vascular endothelial cells [39]. VEGF-C, which regulates lymphatic endothelial cell proliferation via its association with VEGFR-3 [40– ...
The Ndc80p Complex from Saccharomyces cerevisiae Contains
... several components that colocalize with the spindle microtubules close to the nuclear side of the SPB. These components were identified either by a monoclonal screen (Rout and Kilmartin, 1990) or by MALDI mass spectrometric analysis of the enriched spindle poles (Wigge et al., 1998). A particularly ...
... several components that colocalize with the spindle microtubules close to the nuclear side of the SPB. These components were identified either by a monoclonal screen (Rout and Kilmartin, 1990) or by MALDI mass spectrometric analysis of the enriched spindle poles (Wigge et al., 1998). A particularly ...
The constant beat: cardiomyocytes adapt their forces by equal
... Mechanical properties of tissues strongly affect embedded mammalian cells. The consequences extend from simple, small adaptations of rather isolated cellular structures all the way to initiation of very complex differentiation pathways. One of the most potent mechanical signals is the elasticity of ...
... Mechanical properties of tissues strongly affect embedded mammalian cells. The consequences extend from simple, small adaptations of rather isolated cellular structures all the way to initiation of very complex differentiation pathways. One of the most potent mechanical signals is the elasticity of ...
The lipid phosphatase LPP3 regulates extra
... are glycoproteins with a channel-like structure containing six putative transmembrane domains (Kanoh et al., 1997) and were first characterized from their ability to dephosphorylate phosphatidic acid (PA) to produce diacylglycerol (DAG). Since PA and DAG act as potent signaling molecules, LPPs play ...
... are glycoproteins with a channel-like structure containing six putative transmembrane domains (Kanoh et al., 1997) and were first characterized from their ability to dephosphorylate phosphatidic acid (PA) to produce diacylglycerol (DAG). Since PA and DAG act as potent signaling molecules, LPPs play ...
Tissue engineering
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.