Involvement of reactive oxygen species in lanthanum
... the effect of La on LR formation, we also analysed the initiation of LRP. As shown in Supplementary Fig. S1A, LRP initiation was increased in all four stages following exposure to 10–300 μM La. Consistent with the increased number of LRs, expression of three key marker genes involved in LR developme ...
... the effect of La on LR formation, we also analysed the initiation of LRP. As shown in Supplementary Fig. S1A, LRP initiation was increased in all four stages following exposure to 10–300 μM La. Consistent with the increased number of LRs, expression of three key marker genes involved in LR developme ...
Vps41 Phosphorylation and the Rab Ypt7 Control the Targeting of
... link the in vivo and in vitro effects observed in the yck3⌬ mutant to Vps41 function, we searched for the phosphorylation sites in the protein. The Vps41 phosphorylation results in a size shift on gels and is observed in vitro if vacuole-containing membranes are incubated in the presence of ATP (Fig ...
... link the in vivo and in vitro effects observed in the yck3⌬ mutant to Vps41 function, we searched for the phosphorylation sites in the protein. The Vps41 phosphorylation results in a size shift on gels and is observed in vitro if vacuole-containing membranes are incubated in the presence of ATP (Fig ...
Compounds from Wild Mushrooms with Antitumor
... Czech Republic as a functional food for the treatment of rectal cancer [19]. Compound 24 was also isolated from Daedalea dickinsii. MMPs mediate physiological extracellular matrix remodelling and have been implicated in several pathological processes including tumor growth and metastasis [37]. In hu ...
... Czech Republic as a functional food for the treatment of rectal cancer [19]. Compound 24 was also isolated from Daedalea dickinsii. MMPs mediate physiological extracellular matrix remodelling and have been implicated in several pathological processes including tumor growth and metastasis [37]. In hu ...
Organelle communication - Repositorio Académico
... Dynamic organelle interaction controls cell bioenergetics, substrate transport and Ca2+ homeostasis among others. Alterations in such interorganelle contacts directly affect cellular physiology and, as expected, are associated with pathology (Fig. 2). For instance, ER–mitochondria contacts are relev ...
... Dynamic organelle interaction controls cell bioenergetics, substrate transport and Ca2+ homeostasis among others. Alterations in such interorganelle contacts directly affect cellular physiology and, as expected, are associated with pathology (Fig. 2). For instance, ER–mitochondria contacts are relev ...
the process of selection of erythromycin
... From a great number of pairs isolated, those that remained united by a cytoplasmic bridge after fertilization were selected for study. The presence of this bridge indicates that cytoplasm, including mitochondria, has been exchanged between the mates. The bridges are usually transient (5 to 20 min in ...
... From a great number of pairs isolated, those that remained united by a cytoplasmic bridge after fertilization were selected for study. The presence of this bridge indicates that cytoplasm, including mitochondria, has been exchanged between the mates. The bridges are usually transient (5 to 20 min in ...
CELL MOTILITY: Spatial and Temporal Regulation of
... phase viscosity of small solutes is only 10% to 30% less in cytoplasm than in water [reviewed in (13)]. Although diffusion can be the principle mechanism of molecular movement for interactions on a ⬃ 20 nm scale, it cannot completely explain the mechanism by which molecules move over greater distanc ...
... phase viscosity of small solutes is only 10% to 30% less in cytoplasm than in water [reviewed in (13)]. Although diffusion can be the principle mechanism of molecular movement for interactions on a ⬃ 20 nm scale, it cannot completely explain the mechanism by which molecules move over greater distanc ...
IGF signaling directs ventricular cardiomyocyte
... factors secreted by the epicardium (for a review, see Sucov et al., 2009). For example, blocking the formation of the epicardium in chick embryos by physical obstruction resulted in a hypoplastic ventricular wall in the denuded region (Gittenberger-de Groot et al., 2000; Manner et al., 2005). Simila ...
... factors secreted by the epicardium (for a review, see Sucov et al., 2009). For example, blocking the formation of the epicardium in chick embryos by physical obstruction resulted in a hypoplastic ventricular wall in the denuded region (Gittenberger-de Groot et al., 2000; Manner et al., 2005). Simila ...
Molecular Regulation of Vascular Cambium Identity and Activity
... their animal counterparts are reservoirs of cells that can both produce new cells for the generation of new tissues and organs, and self-maintain indeterminately via asymmetric cell division. The asymmetric division of an initial cell generates two daughter cells; one remains as an undifferentiated ...
... their animal counterparts are reservoirs of cells that can both produce new cells for the generation of new tissues and organs, and self-maintain indeterminately via asymmetric cell division. The asymmetric division of an initial cell generates two daughter cells; one remains as an undifferentiated ...
IN VITRO BARK EXTRACTS
... new, plant based, risk-free, superior compounds with novel antimicrobial and anticancer activities is the need of the day. The aim of this study was to evaluate the antimicrobial and anticancer effects of bark of Cinnamomum zeylanicum. The antimicrobial activity of extracts of Cinnamomum zeylanicum ...
... new, plant based, risk-free, superior compounds with novel antimicrobial and anticancer activities is the need of the day. The aim of this study was to evaluate the antimicrobial and anticancer effects of bark of Cinnamomum zeylanicum. The antimicrobial activity of extracts of Cinnamomum zeylanicum ...
The 14-3-3 gene par-5 is required for germline development and
... deregulation, the accumulation of endogenous DNA damage and genomic instability. Moreover, par-5 was required for checkpointinduced cell cycle arrest in response to DNA-damaging agents. We propose a model in which PAR-5 regulates CDK-1 phosphorylation to prevent premature mitotic entry. This study o ...
... deregulation, the accumulation of endogenous DNA damage and genomic instability. Moreover, par-5 was required for checkpointinduced cell cycle arrest in response to DNA-damaging agents. We propose a model in which PAR-5 regulates CDK-1 phosphorylation to prevent premature mitotic entry. This study o ...
RECQ5 helicase promotes resolution of conflicts between
... with RNAPII during transcription elongation (Izumikawa et al., 2008; Kanagaraj et al., 2010). It also localizes to DNA replication foci throughout S phase and interacts physically with the proliferating cell nuclear antigen (PCNA), a key component of the replisome (Kanagaraj et al., 2006). A recent ...
... with RNAPII during transcription elongation (Izumikawa et al., 2008; Kanagaraj et al., 2010). It also localizes to DNA replication foci throughout S phase and interacts physically with the proliferating cell nuclear antigen (PCNA), a key component of the replisome (Kanagaraj et al., 2006). A recent ...
Correlating single cell motility with population growth dynamics
... the bulk fluid volumes handled in bioreactors, motility of individual bacterial cells is not considered to influence bioreactor operations. However, with increasing interest in localized fluid flow inside reactors, along with the bulk flow, it is important to ask the question whether individual moti ...
... the bulk fluid volumes handled in bioreactors, motility of individual bacterial cells is not considered to influence bioreactor operations. However, with increasing interest in localized fluid flow inside reactors, along with the bulk flow, it is important to ask the question whether individual moti ...
Differential Expression Control and Polarized Distribution of Plasma
... cell (Fig. 1F, H, I). Although in non-dividing cells the fluorescence of GFP–SYP132 was only detected on the PM, in dividing cells its fluorescence was also observed in cytosolic punctate structures in addition to the cell plates (asterisks in Fig. 1F). It has been reported elsewhere that PM-localized ...
... cell (Fig. 1F, H, I). Although in non-dividing cells the fluorescence of GFP–SYP132 was only detected on the PM, in dividing cells its fluorescence was also observed in cytosolic punctate structures in addition to the cell plates (asterisks in Fig. 1F). It has been reported elsewhere that PM-localized ...
Vacuolar Function in the Phosphate Homeostasis of the Yeast
... ing organisms. We examined growth response of yeast to constant (Fig. 2A). The intensity of signal assigned to inorphosphate starvation. Wild-type cells (YW5-1B) grown to ganic phosphate in the cytosol did not change during the exponential phase in YEPD were transferred to synthetic first four hours ...
... ing organisms. We examined growth response of yeast to constant (Fig. 2A). The intensity of signal assigned to inorphosphate starvation. Wild-type cells (YW5-1B) grown to ganic phosphate in the cytosol did not change during the exponential phase in YEPD were transferred to synthetic first four hours ...
Medicinal Chemistry of Antifungal Agents
... Fungal infections fall into two distinct categories: ...
... Fungal infections fall into two distinct categories: ...
Protein phosphatases and the regulation of mitosis
... ions for catalysis. PPM family members function in signal transduction and DNA damage pathways (Lu et al., 2004), and it is therefore the PPP family that is most commonly associated with mitotic regulation (Axton et al., 1990; Felix et al., 1990; Picard et al., 1989). Remarkably, brief treatment of ...
... ions for catalysis. PPM family members function in signal transduction and DNA damage pathways (Lu et al., 2004), and it is therefore the PPP family that is most commonly associated with mitotic regulation (Axton et al., 1990; Felix et al., 1990; Picard et al., 1989). Remarkably, brief treatment of ...
Enzymatic lysis of microbial cells
... expression of lysozyme in E. coli; however, in this host HEWL is produced inactive as inclusion bodies (Schlörb et al. 2005). More successful have been the attempts of expression in different strains of Aspergillus niger (Archer et al. 1990; Mainwaring et al. 1999; Gyamerah et al. 2002; Gheshlaghi ...
... expression of lysozyme in E. coli; however, in this host HEWL is produced inactive as inclusion bodies (Schlörb et al. 2005). More successful have been the attempts of expression in different strains of Aspergillus niger (Archer et al. 1990; Mainwaring et al. 1999; Gyamerah et al. 2002; Gheshlaghi ...
1 - UvA-DARE - University of Amsterdam
... al., 2007). Despite the highly cell type-specific expression pattern, of these over 70 IF proteins, they all have a similar protein build up. IF proteins consist of an alpha helical rod domain, which is flanked by non-helical head and tail domains (Reeves et al., 1989), see Figure 1. The central rod ...
... al., 2007). Despite the highly cell type-specific expression pattern, of these over 70 IF proteins, they all have a similar protein build up. IF proteins consist of an alpha helical rod domain, which is flanked by non-helical head and tail domains (Reeves et al., 1989), see Figure 1. The central rod ...
Size, shape, and arrangement of native cellulose fibrils in maize cell
... senescent maize, which does not necessarily represent a real native structure per se. While walls of parenchyma cells may still reserve some of the native characteristics, wood cells are nevertheless already dead as they are in living plant. In this case, wall dehydration after plant senescence may ...
... senescent maize, which does not necessarily represent a real native structure per se. While walls of parenchyma cells may still reserve some of the native characteristics, wood cells are nevertheless already dead as they are in living plant. In this case, wall dehydration after plant senescence may ...
An Equatorial Contractile Mechanism Drives Cell Elongation but not
... transcription factor brachyury, is completed at the 110 cell stage [42,43]. During gastrulation, 10 notochord precursors undergo two rounds of cell division and the resulting 40 cells form a monolayer epithelium anterior to the blastopore [8,11,44,45]. Subsequently, in approximately 3 h up to the ea ...
... transcription factor brachyury, is completed at the 110 cell stage [42,43]. During gastrulation, 10 notochord precursors undergo two rounds of cell division and the resulting 40 cells form a monolayer epithelium anterior to the blastopore [8,11,44,45]. Subsequently, in approximately 3 h up to the ea ...
Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication (replication) that produces two daughter cells. In prokaryotes which lack a cell nucleus, the cell cycle occurs via a process termed binary fission. In cells with a nucleus, as in eukaryotes, the cell cycle can be divided into three periods: interphase, the mitotic (M) phase, and cytokinesis. During interphase, the cell grows, accumulating nutrients needed for mitosis, preparing it for cell division and duplicating its DNA. During the mitotic phase, the cell splits itself into two distinct daughter cells. During the final stage, cytokinesis, the new cell is completely divided. To ensure the proper division of the cell, there are control mechanisms known as cell cycle checkpoints.The cell-division cycle is a vital process by which a single-celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. After cell division, each of the daughter cells begin the interphase of a new cycle. Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell division.