
NuMA assembles into an extensive filamentous structure when
... NuMA is a 236 kDa protein that participates in the organization of the mitotic spindle despite its strict localization in the nucleus during interphase. To test how cells progress through mitosis when NuMA is localized in the cytoplasm instead of the nucleus, we have deleted the nuclear localization ...
... NuMA is a 236 kDa protein that participates in the organization of the mitotic spindle despite its strict localization in the nucleus during interphase. To test how cells progress through mitosis when NuMA is localized in the cytoplasm instead of the nucleus, we have deleted the nuclear localization ...
Localization of Collagenase at the Basal Plasma Membrane of a
... human cancer cell lines. In this report we describe the localization of interstitial collagenase at the basal plasma membrane of the human pancreatic cancer cell line RWP-I, using immunofluorescence and ultrastructural immunogold labeling techniques. Collagenase was expressed on the extracellular fa ...
... human cancer cell lines. In this report we describe the localization of interstitial collagenase at the basal plasma membrane of the human pancreatic cancer cell line RWP-I, using immunofluorescence and ultrastructural immunogold labeling techniques. Collagenase was expressed on the extracellular fa ...
NUCLEAR AND CYTOPLASMIC STAINING
... The cytoskeleton (also CSK) is a cellular "scaffolding" or "skeleton" contained within the cytoplasm and is made out of protein. The cytoskeleton is present in all cells; it was once thought to be uni ...
... The cytoskeleton (also CSK) is a cellular "scaffolding" or "skeleton" contained within the cytoplasm and is made out of protein. The cytoskeleton is present in all cells; it was once thought to be uni ...
A metabolic perspective of Peto`s paradox and cancer
... synthesis. Signalling pathways also activate transcriptional programmes in the nucleus, which produce mRNAs that are essential for ribosome biogenesis, protein, nucleic acid, lipid and carbohydrate synthesis [13,22,23]. In essence, the stimulated cell is a biochemical reaction vessel that drives nut ...
... synthesis. Signalling pathways also activate transcriptional programmes in the nucleus, which produce mRNAs that are essential for ribosome biogenesis, protein, nucleic acid, lipid and carbohydrate synthesis [13,22,23]. In essence, the stimulated cell is a biochemical reaction vessel that drives nut ...
5. Parvoviral Host Range and Cell Entry Mechanisms.
... B. The genus Parvovirus Much of our knowledge of the molecular biology and pathogenic potential of the family Parvoviridae has been derived by studying members of the genus Parvovirus, which typically grow efficiently in cell culture, are open to reverse and forward genetic analysis, and predominant ...
... B. The genus Parvovirus Much of our knowledge of the molecular biology and pathogenic potential of the family Parvoviridae has been derived by studying members of the genus Parvovirus, which typically grow efficiently in cell culture, are open to reverse and forward genetic analysis, and predominant ...
Orthologs of Arabidopsis thaliana stomatal bHLH
... (see Tables S1 and S2 in the supplementary material). Despite strong similarity within these two domains, SPCH, MUTE and FAMA each contain unique features, allowing orthologs to be assigned unambiguously. FAMA and SPCH contain N-terminal acidic domains (with limited sequence similarity between them, ...
... (see Tables S1 and S2 in the supplementary material). Despite strong similarity within these two domains, SPCH, MUTE and FAMA each contain unique features, allowing orthologs to be assigned unambiguously. FAMA and SPCH contain N-terminal acidic domains (with limited sequence similarity between them, ...
Tansley review - Professor Gero Steinberg
... motors play active roles in organizing a polar MT array. In exponentially growing cultures of yeast-like cells, c. 50% of the sporidia are in the G2 phase (McCann & Snetselaar, 1997; Garcia-Muse et al., 2004). At this stage, the cells are actively growing at one cell pole and contain three to six MT ...
... motors play active roles in organizing a polar MT array. In exponentially growing cultures of yeast-like cells, c. 50% of the sporidia are in the G2 phase (McCann & Snetselaar, 1997; Garcia-Muse et al., 2004). At this stage, the cells are actively growing at one cell pole and contain three to six MT ...
PDF
... not peer-reviewed) is the author/funder. All rights reserved. No reuse allowed without permission. ...
... not peer-reviewed) is the author/funder. All rights reserved. No reuse allowed without permission. ...
Example of a scientific poster - SPUR
... intestinal bacteria community differed between wild type and CagA expressing flies. We dissected and plated out homogenized CagA and control guts. We observed no significant increase in the proportion of Lactobacillus bacteria in CagA flies as compared to control flies, although the data suggested s ...
... intestinal bacteria community differed between wild type and CagA expressing flies. We dissected and plated out homogenized CagA and control guts. We observed no significant increase in the proportion of Lactobacillus bacteria in CagA flies as compared to control flies, although the data suggested s ...
Plasmodesmata-Mediated Cell-to-Cell Communication in the Shoot
... however, the role of ARRs movement in the SAM is unknown, but appears to be independent of CK signaling. Recently, it has also been reported that the CK signaling inhibitor ARABIDOPSIS HISTIDINE PHOSPHOTRANSFER PROTEIN 6 (AHP6) acts as a mobile signal to generate positional information during organ ...
... however, the role of ARRs movement in the SAM is unknown, but appears to be independent of CK signaling. Recently, it has also been reported that the CK signaling inhibitor ARABIDOPSIS HISTIDINE PHOSPHOTRANSFER PROTEIN 6 (AHP6) acts as a mobile signal to generate positional information during organ ...
File
... Phases of Cell Growth (cont.) Phase G2: post-synthetic phase in which the cell prepares for mitosis by producing RNA and specialized proteins Mitosis divides the cell into two G1 daughter cells G1 cells may advance again to S phase or pass into a non-proliferative stage (G0) S phase: stage of ...
... Phases of Cell Growth (cont.) Phase G2: post-synthetic phase in which the cell prepares for mitosis by producing RNA and specialized proteins Mitosis divides the cell into two G1 daughter cells G1 cells may advance again to S phase or pass into a non-proliferative stage (G0) S phase: stage of ...
Myosin X is a downstream effector of PI(3)K during phagocytosis articles
... PH domains of Myo10 inhibited phagocytosis (Fig. 4b). In contrast, expression of GFP-tagged full-length Myo10 (Myo10 WT), or untagged full-length Myo10 (Myo10 WT*), did not result in a significant inhibition of phagocytosis (Fig. 4b). The lack of an effect on phagocytosis by some of the constructs w ...
... PH domains of Myo10 inhibited phagocytosis (Fig. 4b). In contrast, expression of GFP-tagged full-length Myo10 (Myo10 WT), or untagged full-length Myo10 (Myo10 WT*), did not result in a significant inhibition of phagocytosis (Fig. 4b). The lack of an effect on phagocytosis by some of the constructs w ...
The AtRAD51C Gene Is Required for Normal Meiotic Chromosome
... chiasmata, which, in combination with sister chromatid cohesion, maintain the association between homologs in the form of bivalents, ensuring proper segregation of homologs at anaphase I. Synapsis, the formation of synaptonemal complexes (SCs) between closely associated chromosomes, has also been im ...
... chiasmata, which, in combination with sister chromatid cohesion, maintain the association between homologs in the form of bivalents, ensuring proper segregation of homologs at anaphase I. Synapsis, the formation of synaptonemal complexes (SCs) between closely associated chromosomes, has also been im ...
Electrocardioqraphic criteria for predicting the site of coronary artery
... The shutting off ; after the plasmid has established itself in the recipient cell results in shutting off the activity of the pheromone by two functions encoded on the plasmid; one involves a reduction of the pheromone production, and other by production of specific inhibitor peptide which encoded b ...
... The shutting off ; after the plasmid has established itself in the recipient cell results in shutting off the activity of the pheromone by two functions encoded on the plasmid; one involves a reduction of the pheromone production, and other by production of specific inhibitor peptide which encoded b ...
Asymmetric adhesion of rod-shaped bacteria controls microcolony
... pole is renewed at each generation (Figure S4A), but Acell remains positive with values similar to the ones obtained for one-sided ablations (Fig. 2C). These experiments show that adhesion at the old pole fully matures over one cell cycle since both modes of ...
... pole is renewed at each generation (Figure S4A), but Acell remains positive with values similar to the ones obtained for one-sided ablations (Fig. 2C). These experiments show that adhesion at the old pole fully matures over one cell cycle since both modes of ...
Regulation of tubulin heterodimer partitioning during interphase and
... aberrancies. Interestingly, we also observed the same phenotype by overexpressing the wild type Op18 protein. Thus, either excessive levels of wild type Op18 or normal levels of mutated hyper-active Op18 seems likely to contribute to tumor progression by exacerbating chromosomal instability. ...
... aberrancies. Interestingly, we also observed the same phenotype by overexpressing the wild type Op18 protein. Thus, either excessive levels of wild type Op18 or normal levels of mutated hyper-active Op18 seems likely to contribute to tumor progression by exacerbating chromosomal instability. ...
PDF
... (Sahai-Hernandez et al., 2012; Sahai-Hernandez and Nystul, 2013). The FSC contributes to formation of its own niche through secretion of the extracellular matrix (ECM) protein Laminin A (LanA), which anchors the FSC to the 2a/2b border and controls FSC proliferation through its function as an integr ...
... (Sahai-Hernandez et al., 2012; Sahai-Hernandez and Nystul, 2013). The FSC contributes to formation of its own niche through secretion of the extracellular matrix (ECM) protein Laminin A (LanA), which anchors the FSC to the 2a/2b border and controls FSC proliferation through its function as an integr ...
Expression Sequences and Distribution of Two Primary Cell
... the large Stokes shift makes it easy to distinguish the emitted light (bright yellow) from the tissue autofluorescence (green) that can then be eliminated using appropriate filters. Both N-CAM and L-CAM were detected at stage 2 of development. The staining for both molecules was diffuse in the cytop ...
... the large Stokes shift makes it easy to distinguish the emitted light (bright yellow) from the tissue autofluorescence (green) that can then be eliminated using appropriate filters. Both N-CAM and L-CAM were detected at stage 2 of development. The staining for both molecules was diffuse in the cytop ...
Smectic-A-filled birefringent elements and fast switching twisted dual
... and optical properties of the deflector兲. For example, the active element can be electrically switched by a 90-deg twisted nematic 共TN兲 cell, followed by a passive birefringent prism that separates the beam into two channels, depending on the beam polarization 共Fig. 1兲. Depending on the applied volt ...
... and optical properties of the deflector兲. For example, the active element can be electrically switched by a 90-deg twisted nematic 共TN兲 cell, followed by a passive birefringent prism that separates the beam into two channels, depending on the beam polarization 共Fig. 1兲. Depending on the applied volt ...
Lesson Overview
... Many protists have complex sexual life cycles in which they alternate between a diploid and a haploid phase, a process known as alternation of generations. ...
... Many protists have complex sexual life cycles in which they alternate between a diploid and a haploid phase, a process known as alternation of generations. ...
Nup358 interacts with APC and plays a role in cell polarization
... anti-Nup358 antibodies and the immunoprecipitate was probed for the presence of APC by western blotting. Rabbit IgG (Rb IgG) was used in control IP. (B) Endogenous Nup358 is recruited to a subset of microtubule plus ends that are proximal to the cell cortex by the exogenously expressed APC. COS-7 ce ...
... anti-Nup358 antibodies and the immunoprecipitate was probed for the presence of APC by western blotting. Rabbit IgG (Rb IgG) was used in control IP. (B) Endogenous Nup358 is recruited to a subset of microtubule plus ends that are proximal to the cell cortex by the exogenously expressed APC. COS-7 ce ...
Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication (replication) that produces two daughter cells. In prokaryotes which lack a cell nucleus, the cell cycle occurs via a process termed binary fission. In cells with a nucleus, as in eukaryotes, the cell cycle can be divided into three periods: interphase, the mitotic (M) phase, and cytokinesis. During interphase, the cell grows, accumulating nutrients needed for mitosis, preparing it for cell division and duplicating its DNA. During the mitotic phase, the cell splits itself into two distinct daughter cells. During the final stage, cytokinesis, the new cell is completely divided. To ensure the proper division of the cell, there are control mechanisms known as cell cycle checkpoints.The cell-division cycle is a vital process by which a single-celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. After cell division, each of the daughter cells begin the interphase of a new cycle. Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell division.