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Catalases and PhoB/PhoR system independently contribute to
Catalases and PhoB/PhoR system independently contribute to

... cells electrophoretic profile- Fig. 1(c)) were excised, treated with trypsin and the resulting peptides ...
Leading to a Mild Immunodeficiency Activator trans
Leading to a Mild Immunodeficiency Activator trans

... due to the very poor prognosis of most patients (despite appropriate medical care). We report herein an unusual MHC class II deficiency phenotype in three affected siblings. Two siblings, now 21 and 22 years old, are mildly affected, and the third, who is 24 years old, is asymptomatic. However, apar ...
The hypersensitive response is associated with host and nonhost
The hypersensitive response is associated with host and nonhost

... growing lesions (1.2 mm/day). Plants with lower levels of partial resistance, such as S. arnezii ´ hondelmannii72, displayed higher IEs (86%) and LGRs (2.4 mm/ day). Susceptible clones became fully infected and showed fast expanding lesions (up to 4.0 mm/day). In general, IE and LGR appeared to be c ...
Metaplastic carcinoma of the breast: A clinicopathological review
Metaplastic carcinoma of the breast: A clinicopathological review

... Methods-Data of 11 patients with metaplastic breast carcinoma were retrospectively reviewed in a 3 years period. Results- The patients ages ranged from 28 years to 70 years (median 49 years). The tumours were 4 to 10 cm (median 7 cm) in size. Patients underwent modified radical mastectomy and one pa ...
The dendritic cell side of the immunological synapse
The dendritic cell side of the immunological synapse

... mobility of antibodies against CD3 incorporated in bilayers (as surrogate APC), this resulted in less signaling within the T cell (55). DCs not only counteract the centripetal forces conferred by the T cell cytoskeleton, but also receive signals themselves from T cells at the immunological synapse. ...
Zhang YA, Okada A, Lew CH, McConnell SK
Zhang YA, Okada A, Lew CH, McConnell SK

... cells, but is found in the nuclei of postmitotic neurons within the deep layers of the cortical plate during early postnatal life (Weimann et al., 1999). Here we provide a more detailed description of the time course by which Otx1 undergoes nuclear localization. Cells in the ventricular zone of the ...
A primer on the mouse basal body
A primer on the mouse basal body

... novo synthesis of centrioles in human cells is error prone, suggesting that the cell’s ability to construct a structurally accurate centriole may be facilitated by the existence of a pre-existing centriole [76]. Loss of mouse Sas4 (also called Cenpj) disrupts formation of centrioles, basal bodies, a ...
Nitrogen gas flushing can be bactericidal: the temperature
Nitrogen gas flushing can be bactericidal: the temperature

... Milk is colonized by numerous “psychrotrophic” or “psychrotolerant” bacterial types which can easily grow at refrigeration temperatures and induce spoilage (Cousin, 1982; Hayes and Boor, 2001). Most psychrotrophic bacteria found in raw milk, many of which are Gram negative bacteria, are generally co ...
PDF
PDF

... progeny of these escaper homozygotes had the same rate of lethality as progeny from heterozygous mothers, indicating that there was no maternal effect on lethality (Fig. 2A). ...
Remapping by hippocampal place cells
Remapping by hippocampal place cells

... cause place cells to show complex remapping have much in common with the kinds of stimuli that behavioural psychologists have manipulated in traditional contextual learning experiments, we refer to such influences on place cells as “contextual stimuli”. This has led us to propose an operational defi ...
Cell Lineage and Fate Map of the Primary Somatoblast of the
Cell Lineage and Fate Map of the Primary Somatoblast of the

... with an Axio Imager Z1 microscope (Zeiss) and an ORCA-ER camera (Hamamatsu) using Volocity acquisition software version 5.0 (Perkin Elmer). Ambient temperature was 228C. DIC and fluorescent z-stacks (5 mm over a 40 mm depth) were automatically taken every 10 min for 8 h. Confocal laser scanning micr ...
A Dominant Negative Mutant of Cyclin-Dependent
A Dominant Negative Mutant of Cyclin-Dependent

... the way it occurs in yeast and animal cells. The endoreduplication cell cycle is a variant of the standard mitotic cell cycle in which there are recurrent S- and G-phases without M-phase (Edgar and Orr-Weaver, 2001). The mechanisms that enable cells to sequentially replicate chromosomes without prog ...
Tumor Necrosis Factor-related Apoptosis
Tumor Necrosis Factor-related Apoptosis

... recruitment of Fas-associated protein with death domain. This polypeptide in turn recruits procaspases-8 and -10 to the receptor complex through homotypic interactions involving death effecter domains in Fas-associated protein with death domain and these two apical caspases (4). The resulting activa ...
Cell cycle behavior of human HP1 subtypes: distinct
Cell cycle behavior of human HP1 subtypes: distinct

... showed two different staining patterns: one, a series of bright regularly shaped spots; and the other, less bright irregularly shaped areas with some diffuse staining of the nucleoplasm. HP1β was predominantly found in the irregularly shaped bodies associated with centromeric regions (Fig. 1A, arrow ...
digitalis - Circulation
digitalis - Circulation

... intracellular Na and K achieve a new steady state, the activity of the pump must be augmented. As influx is increased there is evidence that internal Na + increases for a short period of time and then reaches a steady state at a slightly higher level if the increased heart rate is sustained.13 Intra ...
2010118-1045242010PJ..
2010118-1045242010PJ..

... proteins in bryophytes, based on research using genomic resources that are newly available for the moss Physcomitrella patens, provides new insights into plant evolution. In angiosperms, the XTH genes are found in large multi-gene families, probably reflecting the diverse roles of individual XTHs in ...
Merotelic kinetochore orientation occurs frequently during early
Merotelic kinetochore orientation occurs frequently during early

... Accepted 19 June 2003 Journal of Cell Science 116, 4213-4225 © 2003 The Company of Biologists Ltd doi:10.1242/jcs.00716 ...
Levels of Ycg1 Limit Condensin Function during the Cell Cycle
Levels of Ycg1 Limit Condensin Function during the Cell Cycle

... The eukaryotic cell cycle is divided into two distinct parts: interphase, when cell growth and DNA replication occur, and mitosis, when chromosomes are segregated into daughter cells. One major phenotypic difference between these phases is chromosome conformation. Specifically, interphase chromosome ...
the Sec7 family of guanine-nucleotide- exchange factors
the Sec7 family of guanine-nucleotide- exchange factors

... inactive, abortive complex. A separate subclass of Sec7-domain proteins is involved in signal transduction and possess a domain that mediates membrane binding in response to extracellular signals. ...
Stat3 and MMP7 Contribute to Pancreatic Ductal Adenocarcinoma
Stat3 and MMP7 Contribute to Pancreatic Ductal Adenocarcinoma

... Commentator : Dr. Wu Chou Su            ...
The Role of Cyclin B in Meiosis I
The Role of Cyclin B in Meiosis I

... thought to interact with the yeast homolog of the invertebrate cyclins (Booher and Beach, 1987, 1988; Solomon et al., 1988; Goebl and Byers, 1988; Reed et al., 1988). Unfortunately, a direct immunochemical test of the idea that cyclins are components of highly purified, active MPF is precluded at th ...
Sugar signals and the control of plant growth and
Sugar signals and the control of plant growth and

... AMPK, SNF1, and SnRK1, respectively, are heterotrimeric complexes with a catalytic α-subunit, and regulatory β- and γ-subunits. The AMP/ATP ratio allosterically regulates mammalian AMPK, but the plant SnRK1 is instead regulated by sugar phosphates (Ghillebert et al., 2011). SnRK1 activity is repress ...
Small Signaling Peptides in Arabidopsis Development
Small Signaling Peptides in Arabidopsis Development

... Benfey, 2010; Van Norman et al., 2011). Most prominently, directional transport of the phytohormone auxin from one cell to the other provides cues for patterning and development (Vanneste and Friml, 2009; Grunewald and Friml, 2010). However, signaling through direct symplastic transport of transcrip ...
Induction of Lytic Epstein-Barr Virus (EBV) Infection in EBV
Induction of Lytic Epstein-Barr Virus (EBV) Infection in EBV

... with the antiviral drug, GCV, could abort viral replication and prevent release of infectious EBV, while still allowing EBV-specific killing. Phosphorylation of GCV into its triphosphate form is initiated by the early (or lytic cycle) proteins of several herpesviruses, including the HSV-TK protein a ...
Tese Hugo Fraga
Tese Hugo Fraga

... and culture médium supplementation with plant growth regulators are known to affect DNA methylation and protein expression profiles, modulating the phenotype and/or the embryogenic potential. In this context, the aim of this study was to deepen the knowledge about SE and EC cryopreservation of A. an ...
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Cell cycle



The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication (replication) that produces two daughter cells. In prokaryotes which lack a cell nucleus, the cell cycle occurs via a process termed binary fission. In cells with a nucleus, as in eukaryotes, the cell cycle can be divided into three periods: interphase, the mitotic (M) phase, and cytokinesis. During interphase, the cell grows, accumulating nutrients needed for mitosis, preparing it for cell division and duplicating its DNA. During the mitotic phase, the cell splits itself into two distinct daughter cells. During the final stage, cytokinesis, the new cell is completely divided. To ensure the proper division of the cell, there are control mechanisms known as cell cycle checkpoints.The cell-division cycle is a vital process by which a single-celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. After cell division, each of the daughter cells begin the interphase of a new cycle. Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell division.
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