Dissecting sterol function during clathrin-dependent
... lipid bilayer solvent that can interact with peripheral proteins (Simons and Sampaio, 2011). The lipid bilayer results from the self-association of the lipids hydrophobic moieties and the interaction of the hydrophilic moieties with aqueous environments. The same principle acts at the subcellular le ...
... lipid bilayer solvent that can interact with peripheral proteins (Simons and Sampaio, 2011). The lipid bilayer results from the self-association of the lipids hydrophobic moieties and the interaction of the hydrophilic moieties with aqueous environments. The same principle acts at the subcellular le ...
article in press - MPI
... distinguished by marker gene expression restricted to rostral or caudal territories of forming somites. To better understand the generation of segment polarity in vertebrates, we have studied the zebrafish mutant fused somites (fss), because its paraxial mesoderm lacks segment polarity. Previously e ...
... distinguished by marker gene expression restricted to rostral or caudal territories of forming somites. To better understand the generation of segment polarity in vertebrates, we have studied the zebrafish mutant fused somites (fss), because its paraxial mesoderm lacks segment polarity. Previously e ...
Postmortem Diagnosis of Anaphylaxis
... Commercial kits for determination of mast cell tryptase, based on the work of Schwartz et al. (53,54) have been developed (Pharmacia Diagnostics AB, Uppsala, Sweden). The first version measured only the free form of active tryptase (~) in serum. A more sensitive method was subsequently developed (55 ...
... Commercial kits for determination of mast cell tryptase, based on the work of Schwartz et al. (53,54) have been developed (Pharmacia Diagnostics AB, Uppsala, Sweden). The first version measured only the free form of active tryptase (~) in serum. A more sensitive method was subsequently developed (55 ...
Apical ectodermal ridge morphogenesis in limb development is
... characteristic histological appearance. However, the processes governing this compaction are not fully understood. It has been proposed that movements of cells are crucial to achieve the normal stratification and AER morphology, but the contribution of active migration, cell intercalation, different ...
... characteristic histological appearance. However, the processes governing this compaction are not fully understood. It has been proposed that movements of cells are crucial to achieve the normal stratification and AER morphology, but the contribution of active migration, cell intercalation, different ...
Phage adsorption and lytic propagation in
... phage particle subpopulations under starvation conditions: those that can infect starved cells and those that are not able to do. These subpopulations have differences in their ability to adsorb on bacterial cells. So, phage T4 would prevent it adsorption on host cells by retracting its tail fibers ...
... phage particle subpopulations under starvation conditions: those that can infect starved cells and those that are not able to do. These subpopulations have differences in their ability to adsorb on bacterial cells. So, phage T4 would prevent it adsorption on host cells by retracting its tail fibers ...
Cold-Sensitive Cell-Division-Cycle Mutants of Yeast: Isolation, Properties and Pseudoreversion Studies.
... mutants csAlO, csA18, and csH80 (data not shown). Recombinant spores, (i.e. cs+ ts+) were found at a frequency of about 0.25, the value expected if the cs and ts mutations are unlinked. Since the class I1 cs mutations all complement each other, these data suggest that these three cs mutations define ...
... mutants csAlO, csA18, and csH80 (data not shown). Recombinant spores, (i.e. cs+ ts+) were found at a frequency of about 0.25, the value expected if the cs and ts mutations are unlinked. Since the class I1 cs mutations all complement each other, these data suggest that these three cs mutations define ...
(ECM) Binding Sites on the Basal Surface of Embryonic Corneal
... ECM molecules on cytoskeletal morphology is accompanied by a twofold increase in collagen produced by the epithelium. These results led us to speculate that the solubilized ECM molecules bind to the basal epithelial surface at specific binding sites or receptors, and that this interaction results i ...
... ECM molecules on cytoskeletal morphology is accompanied by a twofold increase in collagen produced by the epithelium. These results led us to speculate that the solubilized ECM molecules bind to the basal epithelial surface at specific binding sites or receptors, and that this interaction results i ...
Hairy Root Transformation Using Agrobacterium
... (Glycine max). This reporter greatly increased the percentage detection of transformants and was used as a tool to determine the function of the soybean Nod factor receptor, GmNFR1a (Lin et al., 2011). The tomato genome sequence has facilitated the discovery of many genes that regulate tomato growth ...
... (Glycine max). This reporter greatly increased the percentage detection of transformants and was used as a tool to determine the function of the soybean Nod factor receptor, GmNFR1a (Lin et al., 2011). The tomato genome sequence has facilitated the discovery of many genes that regulate tomato growth ...
Animal mitochondrial biogenesis and function
... q 2001 Elsevier Science Inc. All rights reserved. Keywords: mtDNA; Gene expression; Retrograde communication; Hormonal regulation; Differentiation; Apoptosis ...
... q 2001 Elsevier Science Inc. All rights reserved. Keywords: mtDNA; Gene expression; Retrograde communication; Hormonal regulation; Differentiation; Apoptosis ...
2 - Liu Lab
... Triple-negative breast cancer (TNBC) is a heterogeneous and clinically aggressive disease for which there is no targeted therapy1–3. BET bromodomain inhibitors, which have shown efficacy in several models of cancer4–6, have not been evaluated in TNBC. These inhibitors displace BET bromodomain protei ...
... Triple-negative breast cancer (TNBC) is a heterogeneous and clinically aggressive disease for which there is no targeted therapy1–3. BET bromodomain inhibitors, which have shown efficacy in several models of cancer4–6, have not been evaluated in TNBC. These inhibitors displace BET bromodomain protei ...
Out of the Mouths of Plants: The Molecular Basis of the Evolution
... opposite the site of the most recent asymmetric division, which appears to be BASL’s main site of activity (Dong et al., 2009) (Figure 3). The ectopic overexpression of BASL confers abnormal cell polarization. Interestingly, the loss of asymmetry in a basl mutant resulted in adoption of the stomatal ...
... opposite the site of the most recent asymmetric division, which appears to be BASL’s main site of activity (Dong et al., 2009) (Figure 3). The ectopic overexpression of BASL confers abnormal cell polarization. Interestingly, the loss of asymmetry in a basl mutant resulted in adoption of the stomatal ...
Wnt signaling: a common theme in animal development
... proven to be problematic. There are numerous unpublished tales of failed attempts to produce secreted Wnt proteins in cell culture. In general, overexpression of the genes in cultured cells results in accumulation of misfolded protein in the endoplasmic reticulum (ER; Kitajewski et al. 1992). Secret ...
... proven to be problematic. There are numerous unpublished tales of failed attempts to produce secreted Wnt proteins in cell culture. In general, overexpression of the genes in cultured cells results in accumulation of misfolded protein in the endoplasmic reticulum (ER; Kitajewski et al. 1992). Secret ...
The Role of the Plant Nucleolus in Pre-mRNA Processing
... to the mature 5.8S, 18S and 25–28S rRNAs. Processing of pre-rRNAs involves (a) cleavage of the transcript into precursors of the mature rRNAs and trimming of these precursors to their final size and (b) modification of specific rRNA nucleotides. The best-characterised pathway of pre-rRNA processing ...
... to the mature 5.8S, 18S and 25–28S rRNAs. Processing of pre-rRNAs involves (a) cleavage of the transcript into precursors of the mature rRNAs and trimming of these precursors to their final size and (b) modification of specific rRNA nucleotides. The best-characterised pathway of pre-rRNA processing ...
A Critical Role for Egr-1 Characterization of CD44 Induction by IL-1:
... molecules are up-regulated at inflamed sites in ulcerative colitis (8). Furthermore, three studies have shown that an anti-CD44 Ab, IM7, has antiinflammatory effects in several in vivo models of inflammation (15–17). Finally, binding of low m.w. fragments of hyaluronic acid (HA) to alveolar macropha ...
... molecules are up-regulated at inflamed sites in ulcerative colitis (8). Furthermore, three studies have shown that an anti-CD44 Ab, IM7, has antiinflammatory effects in several in vivo models of inflammation (15–17). Finally, binding of low m.w. fragments of hyaluronic acid (HA) to alveolar macropha ...
Myosin-Powered Membrane Compartment Drives Cytoplasmic
... microtubules and actin microfilaments with associated molecular motors [2–4]. Transport can be achieved by at least two mechanisms: active transport by receptor-mediated attachment of cargo to molecular motors and passive transport with cytosol flow or cytoplasmic streaming. It stands to reason that ...
... microtubules and actin microfilaments with associated molecular motors [2–4]. Transport can be achieved by at least two mechanisms: active transport by receptor-mediated attachment of cargo to molecular motors and passive transport with cytosol flow or cytoplasmic streaming. It stands to reason that ...
Innexin7a forms junctions that stabilize the basal
... division, a single protocell is visible. (F) When the nucleus divides (not visible) the membrane moves further apart. (G) Following separation of the chromosomes (not visible), the membrane begins to invaginate between the new nuclei. (H,I) The membrane continues to invaginate between new nuclei. (J ...
... division, a single protocell is visible. (F) When the nucleus divides (not visible) the membrane moves further apart. (G) Following separation of the chromosomes (not visible), the membrane begins to invaginate between the new nuclei. (H,I) The membrane continues to invaginate between new nuclei. (J ...
Perturbation of Polyamine Catabolism Can Strongly Affect Root
... Indeed, using ultrastructural and immunocytochemical techniques, it has been previously reported that ZmPAO protein is localized in both the cytoplasm and cell wall of developing tracheary elements and in the endodermis of maize primary roots, with a progressive increase of cell wall immunolabeling ...
... Indeed, using ultrastructural and immunocytochemical techniques, it has been previously reported that ZmPAO protein is localized in both the cytoplasm and cell wall of developing tracheary elements and in the endodermis of maize primary roots, with a progressive increase of cell wall immunolabeling ...
HIV-1 Evolves into a Nonsyncytium-Inducing Virus upon Prolonged
... loss of infectivity on the other cell lines. Although speculative, these differences may be relevant for discerning the mechanism(s) behind each phenotype. Env mutations do not change the coreceptor usage The T-cell tropic LAI virus uses the CXCR4 protein as coreceptor for infection. Because the Env ...
... loss of infectivity on the other cell lines. Although speculative, these differences may be relevant for discerning the mechanism(s) behind each phenotype. Env mutations do not change the coreceptor usage The T-cell tropic LAI virus uses the CXCR4 protein as coreceptor for infection. Because the Env ...
in pdf format
... has large economic impacts in the horse industry (1, 2). In general, there are two groups of mares: those that are capable of clearing bacteria that contaminate the uterus following parturition or intrauterine manipulation; and those that are prone to infection, usually older or barren mares with a ...
... has large economic impacts in the horse industry (1, 2). In general, there are two groups of mares: those that are capable of clearing bacteria that contaminate the uterus following parturition or intrauterine manipulation; and those that are prone to infection, usually older or barren mares with a ...
Transcriptional Control of Endothelial Cell Development
... in the transcriptional programs controlling endothelial cell development as Ets proteins. To date, all characterized endothelial enhancers and promoters contain multiple essential ETS binding sites (Table 1), and ETS motifs are strongly associated with endothelial genes throughout the human genome ( ...
... in the transcriptional programs controlling endothelial cell development as Ets proteins. To date, all characterized endothelial enhancers and promoters contain multiple essential ETS binding sites (Table 1), and ETS motifs are strongly associated with endothelial genes throughout the human genome ( ...
Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication (replication) that produces two daughter cells. In prokaryotes which lack a cell nucleus, the cell cycle occurs via a process termed binary fission. In cells with a nucleus, as in eukaryotes, the cell cycle can be divided into three periods: interphase, the mitotic (M) phase, and cytokinesis. During interphase, the cell grows, accumulating nutrients needed for mitosis, preparing it for cell division and duplicating its DNA. During the mitotic phase, the cell splits itself into two distinct daughter cells. During the final stage, cytokinesis, the new cell is completely divided. To ensure the proper division of the cell, there are control mechanisms known as cell cycle checkpoints.The cell-division cycle is a vital process by which a single-celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. After cell division, each of the daughter cells begin the interphase of a new cycle. Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell division.