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Comprehensive Analysis of Human Cytomegalovirus MicroRNA
Comprehensive Analysis of Human Cytomegalovirus MicroRNA

... and cellular factors involved in signaling and cell cycle [15]. In the present work expression and kinetics of 16 mature HCMV miRNAs were examined in different cell culture systems representing permissive, semi-permissive, and quiescent/latent-like infections. THP-1 acute monocytic leukemia cells [1 ...
Characterization of Pinin, A Novel Protein Associated with the
Characterization of Pinin, A Novel Protein Associated with the

... desmosome have now been characterized, key questions remain concerning the molecular organization of the desmosome, the mechanism of desmosomal assembly and disassembly, and the modulation of the desmosome during essential activities of the epithelial cell. We have identified a phosphoprotein with a ...
pdf, 1.1 MB - The Nebenführ Lab
pdf, 1.1 MB - The Nebenführ Lab

... To test whether this distribution of Golgi stacks is truly random we have correlated the number of Golgi stacks in different regions of the cells with the available volume of cytoplasm. For this purpose, cytoplasm was defined as the area covered by the combined fluorescence of our GFP-marker, which ...
Part 3 (Archaea - Updates Book)
Part 3 (Archaea - Updates Book)

... c) Korarcheota are only known from their DNA sequences—nothing more is known about them (they have only recently been discovered). b. Archaea differ in their chemical make-up from other lifeforms. 1) While archaea have many features that look similar to those found on other cells, these features are ...
Sulfated polysaccharides from marine sponges
Sulfated polysaccharides from marine sponges

... with cells from marine sponge in the beginning of the last century (Wilson 1907). This model was based on the observation that dissociated cells from marine sponge go through an aggregation process, in a species-specific way, forming small cellular aggregates. Later, it was observed that this cellul ...
Effects of Organic Cations on the Gram-negative Cell
Effects of Organic Cations on the Gram-negative Cell

... its presumed effect on the cytoplasmic membrane (see Hotchkiss, 1946; Salton, 1g51), could be replaced by other zwitterionic agents such as betaines, or by cationic quaternary ammonium compounds. Many of the latter are themselves highly bactericidal, and perhaps fulfil the function of organic cation ...
Shaping mitotic chromosomes: From classical concepts to molecular
Shaping mitotic chromosomes: From classical concepts to molecular

... remarkable degree of chromosome condensation, even though H3S10 phosphorylation can no longer be detected in the mutant [40]. These observations imply that H3 phosphorylation cannot be the universal determinant of mitotic chromosome condensation. This conclusion is furthermore supported by the findi ...
Mitochondria in Lung Biology and Pathology: More than - AJP-Lung
Mitochondria in Lung Biology and Pathology: More than - AJP-Lung

... hypoxia? Mungai et al. tested the hypothesis that hypoxia activates the cellular energy ...
pdf: Rahman et al. 2007.
pdf: Rahman et al. 2007.

... its regulation of gene expression (Badescu and Napier, 2006; Woodward and Bartel, 2005). However, the pace has been slower for understanding the steps after transcription that engage the machinery of growth. Although it promotes shoot growth, auxin inhibits root growth. Many studies on auxin, both p ...
Ultrastructural studies of t /t mouse embryos
Ultrastructural studies of t /t mouse embryos

... binucleated cell or cells which undergo karyokinesis but not cytokinesis remain larger than the other blastomeres which continue to divide normally. In the binucleate cells there are generally two nucleoli, rarely three nucleoli, per nucleus. These nucleoli are ultrastructurally normal for the stage ...
Co-Expression of Arabidopsis thaliana Phytochelatin Synthase and Treponema denticola
Co-Expression of Arabidopsis thaliana Phytochelatin Synthase and Treponema denticola

... significant growth inhibition was observed in the presence of cysteine (Table I), even though the presence of cysteine desulfhydrase partially reduced the level of growth inhibition. While cells expressing cysteine desulfhydrase accumulated 25% more arsenite than the wild-type strain BY4742 even in t ...
The Importance of High Resolution Chromosome Analysis in the
The Importance of High Resolution Chromosome Analysis in the

... molecules into a microtubule that makes up the spindle fibres. This prevents the chromatids from aligning on the metaphase plate to be pulled apart during anaphase. The stoichiometric relationship between Colcemid® and tubulin needs to be borne in mind when deciding the amount of the mitotic arresta ...
Actin branching in the initiation and maintenance of lamellipodia
Actin branching in the initiation and maintenance of lamellipodia

... imaging and electron tomography of a cell in which a lamellipodium, extending beneath a retracting ruffle, protruded continuously at 2µm/min up to the point of fixation (black arrows Fig.1D, E and supplementary video S1). A section of the tomogram in F shows the actin filaments, readily identified f ...
Temporal Regulation of RNA Polymerase II by Srb10 and Kin28
Temporal Regulation of RNA Polymerase II by Srb10 and Kin28

... timing of CTD phosphorylation in the holoenzyme could determine whether the event had a negative or a positive consequence. Although both kinases are capable of CTD phosphorylation as purified, recombinant kinasecyclin pairs, it is possible that they can function only at certain times when assembled ...
Targeting of Salmonella typhimurium to Vesicles Containing
Targeting of Salmonella typhimurium to Vesicles Containing

... (SCV) upon entry into the host cell. In this study we have examined the intracellular trafficking route of S. typhimurium within epithelial cells. Indirect immunofluorescence analysis showed that bacteria initiated fusion with lysosomal membrane glycoprotein (lgp)-containing compartments "o15 min af ...
Cadherins constitute a superfamily of transmembrane - HAL
Cadherins constitute a superfamily of transmembrane - HAL

... local concentration of cadherin molecules at the cell surface, the recruitment of both cytoskeleton binding proteins and regulating proteins and the reorganization of cytoskeleton network. All these processes are intimately interrelated and their individual contribution to the modulation of cell-cel ...
Role of the RNA-binding protein Roquin in immune homeostasis
Role of the RNA-binding protein Roquin in immune homeostasis

A1982PM90100001
A1982PM90100001

... in serum was not always an accurate measure of the degree of folate deficiency since very low results could be obtained in many patients without any haematological evidence of the deficiency. “A number of groups in Israel, Sweden, Canada, Holland, and Britain had already reported assays of whole blo ...
Practice Test Answer Key
Practice Test Answer Key

... ____ 25. When a female salmon nears the end of her life, she returns to the river where she was born so that she can lay her eggs. This is an example of a. an inherited characteristic. c. a physical adaptation. b. an adaptation. d. a learned behaviour. ____ 26. A frog that buries itself in the mud f ...
Berlin-Buch - Max Delbrück Center for Molecular Medicine
Berlin-Buch - Max Delbrück Center for Molecular Medicine

A leucine aminopeptidase is involved in kinetoplast DNA
A leucine aminopeptidase is involved in kinetoplast DNA

... a single network composed of mutually catenated circular molecules of two categories–maxicircles and minicircles—that are extended and densely packaged into a highly organized discoid structure [1]. The kDNA network is located in the mt lumen adjacent to the basal body of the single flagellum, to wh ...
Molecular and Cellular Mechanisms Whereby the Apical Ectodermal
Molecular and Cellular Mechanisms Whereby the Apical Ectodermal

... research only scratching the surface of the many complex processes involved in the process of making an ordered form. There are many facets of developmental biology; some focusing on cellular mechanisms and behavior with others focusing on organogenesis and the development of entire systems. The ult ...
Microtubules Regulate Dynamic Organization of Vacuoles in
Microtubules Regulate Dynamic Organization of Vacuoles in

... actin microfilaments, rather than microtubules, and that their maintenance and distribution are actin dependent (Ovecka et al. 2005, Higaki et al. 2006). To investigate vacuolar morphology and its regulatory mechanisms, we have, in this study, established a new visualization system using the moss, Ph ...
The control of sexual identity in the Drosophila
The control of sexual identity in the Drosophila

... relative levels, a process known as X chromosome dosage compensation. However, germ cells must turn off dosage compensation, at least at some point in their development, in order to reset this system for the next generation. XX and XY germ cells would have different levels of X chromosome gene expre ...
Here - Muscle Health Research Centre
Here - Muscle Health Research Centre

... accompanying software. Analysis of blots was performed using ImageJ freeware. It should be noted that significant changes in proteins normally used as loading controls (e.g., GAPDH) during skeletal muscle regeneration occur. Therefore, Ponceau-stained membranes were imaged, and an appropriate band w ...
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Cell cycle



The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication (replication) that produces two daughter cells. In prokaryotes which lack a cell nucleus, the cell cycle occurs via a process termed binary fission. In cells with a nucleus, as in eukaryotes, the cell cycle can be divided into three periods: interphase, the mitotic (M) phase, and cytokinesis. During interphase, the cell grows, accumulating nutrients needed for mitosis, preparing it for cell division and duplicating its DNA. During the mitotic phase, the cell splits itself into two distinct daughter cells. During the final stage, cytokinesis, the new cell is completely divided. To ensure the proper division of the cell, there are control mechanisms known as cell cycle checkpoints.The cell-division cycle is a vital process by which a single-celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. After cell division, each of the daughter cells begin the interphase of a new cycle. Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell division.
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