The cell biology of hearing - The Journal of Cell Biology
... the width and thickness of the basilar membrane (Lim, 1980), hair cells at different positions along the cochlear duct are tuned to different frequencies: hair cells at the base of the duct respond to highest frequencies, those at the apex to the lowest frequencies (Liberman, 1982; Müller, 1991, 199 ...
... the width and thickness of the basilar membrane (Lim, 1980), hair cells at different positions along the cochlear duct are tuned to different frequencies: hair cells at the base of the duct respond to highest frequencies, those at the apex to the lowest frequencies (Liberman, 1982; Müller, 1991, 199 ...
Protists - Needham.K12.ma.us
... The protists kingdom is one of the most diverse. Most are unicellular, although some are multicellular. Some are heterotrophs, some are autotrophs and some are…. BOTH! Some protists cannot move while some others have no problem zipping around their surroundings. ...
... The protists kingdom is one of the most diverse. Most are unicellular, although some are multicellular. Some are heterotrophs, some are autotrophs and some are…. BOTH! Some protists cannot move while some others have no problem zipping around their surroundings. ...
Transcription factories
... that the signal increased in these distinct transcript clusters with the duration of labeling (1, 5, and 15 min), suggesting that the clusters marked active synthetic sites. However, the total number of clusters per cell did not increase with longer labeling. This suggests the method is sensitive en ...
... that the signal increased in these distinct transcript clusters with the duration of labeling (1, 5, and 15 min), suggesting that the clusters marked active synthetic sites. However, the total number of clusters per cell did not increase with longer labeling. This suggests the method is sensitive en ...
Serial killers: ordering caspase activation events in apoptosis
... Ordering caspase activation events in apoptosis EA Slee et al ...
... Ordering caspase activation events in apoptosis EA Slee et al ...
Exploring glycoside hydrolase family 5 (GH5) enzymes
... scientist Bernard Henrissat. According to sequence similarity, these enzymes were separated into families with conserved structures and reaction mechanisms. One interesting class of CAZymes is the group of glycoside hydrolases (GHs) containing more than 138000 modules divided into 131 families as of ...
... scientist Bernard Henrissat. According to sequence similarity, these enzymes were separated into families with conserved structures and reaction mechanisms. One interesting class of CAZymes is the group of glycoside hydrolases (GHs) containing more than 138000 modules divided into 131 families as of ...
dextran by suspension-cultured plant cells
... contrast, Preston and his coworkers (1987) found no evidence for endocytosis of FD-70S but reported that fluorescent contaminants of low molecular weight (e.g. FITC compounds) were present in commercial preparations of FDs. These small molecules were internalised via a non-endocytotic pathway and s ...
... contrast, Preston and his coworkers (1987) found no evidence for endocytosis of FD-70S but reported that fluorescent contaminants of low molecular weight (e.g. FITC compounds) were present in commercial preparations of FDs. These small molecules were internalised via a non-endocytotic pathway and s ...
PDF - International Journal of Biological Sciences
... with many accessory proteins. The dynamic reassembly of this intracellular protein network regulates the cell shape, cellular adhesions to the extracellular matrix, and mechanical compliances, i.e., elastic moduli [5, 6]. Such mechanical events are orchestrated to generate cells’ directional movemen ...
... with many accessory proteins. The dynamic reassembly of this intracellular protein network regulates the cell shape, cellular adhesions to the extracellular matrix, and mechanical compliances, i.e., elastic moduli [5, 6]. Such mechanical events are orchestrated to generate cells’ directional movemen ...
Epithelial-Mesenchymal Transition in Pancreatic Carcinoma
... models [34], it is likely that the SMAD4 status defines two subclasses of pancreatic carcinoma with very distinct behavior. In tumors with functional SMAD4, the cytostatic effects of TGF have to be prevented by other mechanisms (e.g., hyperactive Ras signaling, overexpression of Ski, etc.), and thu ...
... models [34], it is likely that the SMAD4 status defines two subclasses of pancreatic carcinoma with very distinct behavior. In tumors with functional SMAD4, the cytostatic effects of TGF have to be prevented by other mechanisms (e.g., hyperactive Ras signaling, overexpression of Ski, etc.), and thu ...
- PlantingScience
... How the Celery Challenge Works: This module is framed as a challenge to cause and explain the most extreme bending in celery petioles (stalks), designed as two guided inquiries and an open inquiry ...
... How the Celery Challenge Works: This module is framed as a challenge to cause and explain the most extreme bending in celery petioles (stalks), designed as two guided inquiries and an open inquiry ...
On the origin, evolution, and nature of programmed cell
... been associated with a great level of diversification.19,20,25 In humans and mice, around twenty gene products that are homologues of the cell death repressor Ced-9 and its antagonist Egl-1 (the Bcl-2 family) have been identified, as well as more than ten homologues of the executioner Ced-3 (the cas ...
... been associated with a great level of diversification.19,20,25 In humans and mice, around twenty gene products that are homologues of the cell death repressor Ced-9 and its antagonist Egl-1 (the Bcl-2 family) have been identified, as well as more than ten homologues of the executioner Ced-3 (the cas ...
Mid-term Review
... Heredity - passing of genetic traits from parent to offspring Characteristics - inherited from parents to offspring Genes - one set of instructions for an inherited trait from each parent Dominant - the trait that seems to cover up another trait. (T)- Capital ...
... Heredity - passing of genetic traits from parent to offspring Characteristics - inherited from parents to offspring Genes - one set of instructions for an inherited trait from each parent Dominant - the trait that seems to cover up another trait. (T)- Capital ...
Jamieson
... All aerobically growing organisms suffer exposure to oxidative stress, caused by partially reduced forms of molecular oxygen, known as reactive oxygen species (ROS). These are highly reactive and capable of damaging cellular constituents such as DNA, lipids and proteins. Consequently, cells from man ...
... All aerobically growing organisms suffer exposure to oxidative stress, caused by partially reduced forms of molecular oxygen, known as reactive oxygen species (ROS). These are highly reactive and capable of damaging cellular constituents such as DNA, lipids and proteins. Consequently, cells from man ...
Serial endosymbiosis or singular event at the origin of eukaryotes?
... radiation as substrate and driving force. I am not persuaded by the concept of a cyanosulfidic protometabolism driven by UV radiation (Patel et al., 2015), but others do find this approach to the origins of life appealing. Margulis’s details, however, lack credibility. She talks about ultraviolet radi ...
... radiation as substrate and driving force. I am not persuaded by the concept of a cyanosulfidic protometabolism driven by UV radiation (Patel et al., 2015), but others do find this approach to the origins of life appealing. Margulis’s details, however, lack credibility. She talks about ultraviolet radi ...
- Wiley Online Library
... The difference between PtdIns3P and PtdIns4P is the phosphate group on the 3- or 4-position of the D-myo-inositol ring. PtdIns3P has previously been imaged using the biosensor YFP–2 · FYVE (Vermeer et al., 2006; Voigt et al., 2005). To investigate whether there is any overlap between PtdIns3P and Pt ...
... The difference between PtdIns3P and PtdIns4P is the phosphate group on the 3- or 4-position of the D-myo-inositol ring. PtdIns3P has previously been imaged using the biosensor YFP–2 · FYVE (Vermeer et al., 2006; Voigt et al., 2005). To investigate whether there is any overlap between PtdIns3P and Pt ...
immunodetection of arabinogalactan proteins in different types of
... in the anther. Those authors suggested that the molecules recognized by MAC 207, which at the beginning are especially abundant on the cell surface, disappear to make room for other substances important for the sexual reproduction process. In Arabidopsis thaliana, Acosta-Garcia and Vielle-Calzada (2 ...
... in the anther. Those authors suggested that the molecules recognized by MAC 207, which at the beginning are especially abundant on the cell surface, disappear to make room for other substances important for the sexual reproduction process. In Arabidopsis thaliana, Acosta-Garcia and Vielle-Calzada (2 ...
Eyes Absent, a key repressor of polar cell fate during
... Drosophila oogenesis provides an excellent system with which to study the mechanisms underlying specification of different cell fates. The Drosophila ovary is made up of germline cells and somatic follicle cells. Germline and somatic stem cells can be found at the anterior end of the ovary in a stru ...
... Drosophila oogenesis provides an excellent system with which to study the mechanisms underlying specification of different cell fates. The Drosophila ovary is made up of germline cells and somatic follicle cells. Germline and somatic stem cells can be found at the anterior end of the ovary in a stru ...
MAIT Cells Precursor Derivatives Activating Mouse Derived Riboflavin
... microbes mentioned above. However, in the absence of an antiMR1–blocking experiment, it is not clear whether the reactivity of the clones was lymphokine mediated or classical MHC or MR1 restricted. These two sets of data (diversity of TCRb repertoire of polyclonal TNF secreting Va7.2+ T cells and di ...
... microbes mentioned above. However, in the absence of an antiMR1–blocking experiment, it is not clear whether the reactivity of the clones was lymphokine mediated or classical MHC or MR1 restricted. These two sets of data (diversity of TCRb repertoire of polyclonal TNF secreting Va7.2+ T cells and di ...
Dynamic Tubular Vacuoles Radiate Through the
... tubules seen with anthocyanin fluorescence (arrows). Labeling of the tonoplast around vacuolar tubules was also confirmed with expression of ShMTP1–GFP (Delhaize et al. 2003). This construct labeled the tonoplast around tubules in the outer cortex of inner epidermal cells (Fig. 5B; Supplementary Movie ...
... tubules seen with anthocyanin fluorescence (arrows). Labeling of the tonoplast around vacuolar tubules was also confirmed with expression of ShMTP1–GFP (Delhaize et al. 2003). This construct labeled the tonoplast around tubules in the outer cortex of inner epidermal cells (Fig. 5B; Supplementary Movie ...
Regulation of the initiation of chromosomal replication in bacteria
... to be more intricate in organisms that undergo a complex life cycle or in those that have to adapt to highly fluctuating environmental conditions. Under unfavourable conditions, the growth rate should be reduced and/or the bacteria should undergo morphological changes. In these organisms the decisio ...
... to be more intricate in organisms that undergo a complex life cycle or in those that have to adapt to highly fluctuating environmental conditions. Under unfavourable conditions, the growth rate should be reduced and/or the bacteria should undergo morphological changes. In these organisms the decisio ...
Chromosome Segregation in Budding Yeast: Sister Chromatid
... tightly together by a conserved protein complex, known as cohesin. In mitosis, the cohesin linkages provide resistance and generate tension to facilitate the attachment of sister chromatids to microtubules emanating from opposite poles. Once all the chromosomes have properly attached to microtubules ...
... tightly together by a conserved protein complex, known as cohesin. In mitosis, the cohesin linkages provide resistance and generate tension to facilitate the attachment of sister chromatids to microtubules emanating from opposite poles. Once all the chromosomes have properly attached to microtubules ...
Mechanistic Modeling of Cancer Tumor Growth Using a Porous
... in cell number. Some cycles of hyperplasia are normal in certain tissues, but the term can also apply to abnormal increases in cell proliferation. Alternatively, dysplasia is abnormal growth, meaning that the cells are physically distinct from normal cells. These cellular abnormalities include alter ...
... in cell number. Some cycles of hyperplasia are normal in certain tissues, but the term can also apply to abnormal increases in cell proliferation. Alternatively, dysplasia is abnormal growth, meaning that the cells are physically distinct from normal cells. These cellular abnormalities include alter ...
Genetic and Molecular Mechanisms Controlling Reactive
... In the present work, the regulation and mechanisms of cellular responses, such as cell death and signalling of systemic acquired acclimation (SAA), in response to environmentally induced oxidative stress in Arabidopsis are characterized. We used the lesion simulating disease1 (lsd1) mutant as a gene ...
... In the present work, the regulation and mechanisms of cellular responses, such as cell death and signalling of systemic acquired acclimation (SAA), in response to environmentally induced oxidative stress in Arabidopsis are characterized. We used the lesion simulating disease1 (lsd1) mutant as a gene ...
Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication (replication) that produces two daughter cells. In prokaryotes which lack a cell nucleus, the cell cycle occurs via a process termed binary fission. In cells with a nucleus, as in eukaryotes, the cell cycle can be divided into three periods: interphase, the mitotic (M) phase, and cytokinesis. During interphase, the cell grows, accumulating nutrients needed for mitosis, preparing it for cell division and duplicating its DNA. During the mitotic phase, the cell splits itself into two distinct daughter cells. During the final stage, cytokinesis, the new cell is completely divided. To ensure the proper division of the cell, there are control mechanisms known as cell cycle checkpoints.The cell-division cycle is a vital process by which a single-celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. After cell division, each of the daughter cells begin the interphase of a new cycle. Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell division.