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The nuclear membrane in multidrug resistance
The nuclear membrane in multidrug resistance

... the nucleus of sensitive cells bound to proteins, whereas MDR cells allow adriamycin into their nuclei by passive diffusion only, with no active transport. This absence of active transport in MDR nuclei has several possible explanations, the two most probable being either that adriamycin binds to di ...
The Involvement of the Fibronectin Type II-like Modules
The Involvement of the Fibronectin Type II-like Modules

Mesoderm induction in Xenopus laevis:responding
Mesoderm induction in Xenopus laevis:responding

... Serum-free conditioned medium from the XTC cell line (Pudney et al. 1973) was prepared as described by Smith (1987) except that the cells were grown on glass roller bottles. For most experiments, XTC-MEF was partially purified from heated conditioned medium by DEAESepharose chromatography followed b ...
Plant Molecular Biology
Plant Molecular Biology

... observed after 24 h DEX treatment (data not shown). However, even after 36 or 48 h treatment, the majority of cells belonged to categories x, y and z (Figure 2B and data not shown). Thus, PCD-like death appears to be the major form of cell death induced by Bax, although necrotic cell death can also ...
Nucleocytoplasmic transport
Nucleocytoplasmic transport

... visible in the electron microscope (Figure 1); certainly Gp62 and NSP1 are accessible to monoclonal antibodies from both the nucleoplasmic and cytoplasmic surfaces and therefore are probably symmetrically distributed. To extend this speculation, the coiled-coil C-terminal domains might interact to f ...
Chapter 31
Chapter 31

... Spores vs Gametes Spore Cell or cell-like structure involved in asexual reproduction May be adapted for dispersal and/or survival in unfavorable conditions Part of life cycle of many ...
Biology I Syllabus
Biology I Syllabus

...  Show how chemical reactions can be represented by chemical formulas?  Explain the difference between organic and inorganic compounds?  Describe the general structure and function of major groups of organic compounds?  Describe the function of enzymes, including how enzyme-substrate specificity ...
Changes in Pectin Structure during Epidermal Cell Elongation in
Changes in Pectin Structure during Epidermal Cell Elongation in

... pectins with a low degree of methylesterification, and JIM7, which recognizes those with a high degree of methylesterification (Knox et al. 1990). In the outer epidermal wall of the elongating region, JIM5 was labeled sparsely on the outer half of the cell wall,with little or no labeling on the inne ...
High-throughput screens for fluorescent dye discovery
High-throughput screens for fluorescent dye discovery

pdf
pdf

... shown above are valid for the cells in direct contact with the ATR crystal, while these estimates do not represent the cells that do not attach to the crystal. This is because the evanescent wave penetrates the cell through an intermediate water film of lower refractive index (when compared to the r ...
Interleukin 1, Interleukin 6, Tumor Necrosis
Interleukin 1, Interleukin 6, Tumor Necrosis

Beta cell restoration
Beta cell restoration

Intersections of lung progenitor cells, lung disease and lung cancer
Intersections of lung progenitor cells, lung disease and lung cancer

Mechanism of Growth Arrest of Chemically
Mechanism of Growth Arrest of Chemically

... clones obtained through 3-methyicholanthrenetransfor (10), or the tumor promoter, TPA (21, 25). DNA virus mation of both of the parent nontransformedlines. The transformed cells, on the other hand, do not growth arrest two transformed lines were AKR-MCA derived from the in G, under usual monolayer c ...
PULP
PULP

...  Collagen increase is noted in the medial & adventitial layers of blood vessels as well.  Decrease in the size of pulp.  Plaques may appear in pulpal vessels.  Calcifications in the walls of blood vessels is found most often in the region near the apical foramen. ...
Cells 1.2
Cells 1.2

... End Show Copyright Pearson Prentice Hall ...
Exit from dormancy in microbial organisms
Exit from dormancy in microbial organisms

... constitute only a small fraction of the population, and although this state does not seem to be a response to environmental stimuli, little is known about how persisters are formed. In Escherichia coli, the kinase HipA phosphorylates the translation factor elongation factor-Tu (EF-Tu) in vitro, and ...
1 Properties of Matter
1 Properties of Matter

... and the body’s interactions with the environment. Identify the basic unit of the nervous system, the neuron, and explain generally how it works. 4.5 Explain how the muscular/skeletal system (skeletal, smooth and cardiac muscle, bones, cartilage, ligaments, tendons) works with other systems to suppor ...
An emerging role for prdm family genes in dorsoventral patterning of
An emerging role for prdm family genes in dorsoventral patterning of

... While many Prdm proteins have only been tested for DNA binding using in vitro systems, ChIP-seq experiments (chromatin immunoprecipitation using Prdmspecific antibodies followed by deep sequencing) have also identified genomic binding sites for a subset of Prdm factors (Prdm1, Prdm3, Prdm13, and Prd ...
315-332
315-332

... A secondary cell wall, if present, is laid down internally to the primary cell wall at the onset of differentiation, once cell growth has ceased. Secondary cell wall composition and ultrastructure in spermatophytes varies from one cell type to another as well as between plant species. This variabili ...
Heat shock proteins: the search for functions.
Heat shock proteins: the search for functions.

... proteolytic digestion products of the bovine clathrin uncoating enzyme. Further evidence was obtained by Bill Welch at Cold Spring Harbor Laboratory who noted that HSP70-1ike proteins have an ATP-binding property and found identity between proteolytic digestion products of HSP70-1ike proteins and th ...
How is pluripotency determined and maintained?
How is pluripotency determined and maintained?

... to the maintenance of pluripotency remains to be confirmed. Mechanisms to maintain self-renewal In order to maintain the stable self-renewal of ES cells, the mechanisms that prevent their differentiation and promote their proliferation must be transmitted to their daughter cells. Thus, the expressio ...
Janice Evans
Janice Evans

... – Fertilization / egg activation • exit from metaphase II arrest and progression into the embryonic cell cycle ...
PDF
PDF

... to the maintenance of pluripotency remains to be confirmed. Mechanisms to maintain self-renewal In order to maintain the stable self-renewal of ES cells, the mechanisms that prevent their differentiation and promote their proliferation must be transmitted to their daughter cells. Thus, the expressio ...
further characterization of the f1
further characterization of the f1

... occur predominantly during DNA synthesis (1, 2) . This phosphorylation occurs both on old preexisting and on newly synthesized Fl after a short post-translational delay (3) . Experimental evidence has also been presented to suggest that the F1 histone of several metaphasearrested cell types exists i ...
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Cell cycle



The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication (replication) that produces two daughter cells. In prokaryotes which lack a cell nucleus, the cell cycle occurs via a process termed binary fission. In cells with a nucleus, as in eukaryotes, the cell cycle can be divided into three periods: interphase, the mitotic (M) phase, and cytokinesis. During interphase, the cell grows, accumulating nutrients needed for mitosis, preparing it for cell division and duplicating its DNA. During the mitotic phase, the cell splits itself into two distinct daughter cells. During the final stage, cytokinesis, the new cell is completely divided. To ensure the proper division of the cell, there are control mechanisms known as cell cycle checkpoints.The cell-division cycle is a vital process by which a single-celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. After cell division, each of the daughter cells begin the interphase of a new cycle. Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell division.
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