Cooke Zeeman 1976 Wavefront model for morphogenesis
... whole body pattern and (b) approximately normal in abnormally small bodies. Naively, a mechanism for achieving this would be to have the preo semitic cells, which are two longitudinal tracts down the body axis, responsive to a particular regular succession of values of the p.i. variable or body grad ...
... whole body pattern and (b) approximately normal in abnormally small bodies. Naively, a mechanism for achieving this would be to have the preo semitic cells, which are two longitudinal tracts down the body axis, responsive to a particular regular succession of values of the p.i. variable or body grad ...
Idh paper revised II - G3: Genes | Genomes | Genetics
... coinciding with the beginning of E93 transcription. This group was assigned to E93 when it was found that one of its alleles ("E931") is associated with a nonsense mutation at codon 995 of the E93 A isoform, near the 3' end of the E93 coding sequence. The other two alleles in this complementation gr ...
... coinciding with the beginning of E93 transcription. This group was assigned to E93 when it was found that one of its alleles ("E931") is associated with a nonsense mutation at codon 995 of the E93 A isoform, near the 3' end of the E93 coding sequence. The other two alleles in this complementation gr ...
PDF - Walter Lab
... Mutations in numerous genes encoding cortical actin patch components lead to defects in endocytosis2, and most of these proteins have homologues in mammalian cells, where they likewise participate in endocytosis. The dynamic assembly of actin patches at the cell cortex is thought to promote the form ...
... Mutations in numerous genes encoding cortical actin patch components lead to defects in endocytosis2, and most of these proteins have homologues in mammalian cells, where they likewise participate in endocytosis. The dynamic assembly of actin patches at the cell cortex is thought to promote the form ...
Glonal analysis of the crustacean segment
... (3)) have been formed by cells of the blastodermic germ disc. Of these, rows (2) and (3) have already been divided once by a mitotic wave to form two rows each. On the animal's right side, the two cells nearest to the median line cleave for the second time and two cells of row (1) cleave for the fir ...
... (3)) have been formed by cells of the blastodermic germ disc. Of these, rows (2) and (3) have already been divided once by a mitotic wave to form two rows each. On the animal's right side, the two cells nearest to the median line cleave for the second time and two cells of row (1) cleave for the fir ...
Metabolic Basis of Visual Cycle Inhibition by Retinoid and
... like farnesylamine also showed inhibitory potency but a short duration of action, probably due to rapid metabolism. These compounds also are reactive nucleophiles with potentially high cellular toxicity. We also evaluated the role of a specific proteinmediated mechanism on retinoid cycle inhibitor u ...
... like farnesylamine also showed inhibitory potency but a short duration of action, probably due to rapid metabolism. These compounds also are reactive nucleophiles with potentially high cellular toxicity. We also evaluated the role of a specific proteinmediated mechanism on retinoid cycle inhibitor u ...
gamma-delta T cells target the red blood cell
... as phosphoantigens, independent of processing or presentation by professional antigen presenting cells.5 The most active phosphoantigens are intermediate products of the deoxy-xylulose-5-phosphate (DOXP) isoprenoid synthesis pathway, which occurs in the Plasmodium apicoplast.6,7 During a primary mal ...
... as phosphoantigens, independent of processing or presentation by professional antigen presenting cells.5 The most active phosphoantigens are intermediate products of the deoxy-xylulose-5-phosphate (DOXP) isoprenoid synthesis pathway, which occurs in the Plasmodium apicoplast.6,7 During a primary mal ...
Multiple mediators of plant programmed cell death: interplay of
... Programmed cell death (PCD) is a process aimed at eliminating redundant or harmful cells during the life cycle of multicellular organisms. For example, PCD is responsible for the removal of excess cells in the developing nervous system, or is activated in defence against infected or mutated cells, p ...
... Programmed cell death (PCD) is a process aimed at eliminating redundant or harmful cells during the life cycle of multicellular organisms. For example, PCD is responsible for the removal of excess cells in the developing nervous system, or is activated in defence against infected or mutated cells, p ...
The retinoblastoma homolog RBR1 mediates localization of the
... mutants are sensitive to hydroxyurea (HU, also called hydroxycarbamide). HU depletes the dNTP pools in a cell by inhibiting ribonucleotide reductase leading to an arrest of replication forks and subsequent DNA breakage (Yarbro, 1992). The response to replication stress is controlled by an intra-S-ph ...
... mutants are sensitive to hydroxyurea (HU, also called hydroxycarbamide). HU depletes the dNTP pools in a cell by inhibiting ribonucleotide reductase leading to an arrest of replication forks and subsequent DNA breakage (Yarbro, 1992). The response to replication stress is controlled by an intra-S-ph ...
12-N. Ohno.indd - PJM ONLINE | Polish Journal of Microbiology
... a 1,2-β-mannosyl linkage within the mannan moiety of these fractions significantly reduced the biological effects described above (Tada et al., 2008; Shinohara et al., 2006). This result was also supported by investigations into the activity of cell wall mannan extracts of C. albicans, the structure ...
... a 1,2-β-mannosyl linkage within the mannan moiety of these fractions significantly reduced the biological effects described above (Tada et al., 2008; Shinohara et al., 2006). This result was also supported by investigations into the activity of cell wall mannan extracts of C. albicans, the structure ...
cell structure and function cell structure and function
... Prokaryotes (proh-KAR-ee-OHTS) are organisms that lack a membranebound nucleus and membrane-bound organelles. Although prokaryotic cells lack a nucleus, their genetic information—in the form of DNA—is often concentrated in a part of the cell called the nucleoid. Figure 4 -7 shows a typical prokaryot ...
... Prokaryotes (proh-KAR-ee-OHTS) are organisms that lack a membranebound nucleus and membrane-bound organelles. Although prokaryotic cells lack a nucleus, their genetic information—in the form of DNA—is often concentrated in a part of the cell called the nucleoid. Figure 4 -7 shows a typical prokaryot ...
Chapter 3: Movement Of Substances Across the Substances
... (a)The following information is about plasma membrane. The plasma membrane is semi-permeable and allows certain substances to move across. Based on the above statement, describe how an amino acid molecule is transported across the plasma membrane into the cell. P1-Amino acid is a large water soluble ...
... (a)The following information is about plasma membrane. The plasma membrane is semi-permeable and allows certain substances to move across. Based on the above statement, describe how an amino acid molecule is transported across the plasma membrane into the cell. P1-Amino acid is a large water soluble ...
A Shift toward Smaller Cell Size via Manipulation of Cell Cycle Gene
... (Wyrzykowska et al., 2002). However, the technical difficulty of dissecting tobacco leaf primordia and the lack of a system to reliably quantify the outcome on cell division and leaf shape at time points after our manipulations meant that our investigation lacked sufficient resolution to quantify th ...
... (Wyrzykowska et al., 2002). However, the technical difficulty of dissecting tobacco leaf primordia and the lack of a system to reliably quantify the outcome on cell division and leaf shape at time points after our manipulations meant that our investigation lacked sufficient resolution to quantify th ...
Fission yeast Myo51 is a meiotic spindle pole body component with
... CAR during mitosis, and also to the SPBs throughout meiosis (Fig. 4N), indicating that Myo51 localisation is independent of Cdc11 or SIN activity. To explore the dependence of Myo51 upon actin for its localisation during meiosis, we created a strain containing the myo51-mCherry allele together with ...
... CAR during mitosis, and also to the SPBs throughout meiosis (Fig. 4N), indicating that Myo51 localisation is independent of Cdc11 or SIN activity. To explore the dependence of Myo51 upon actin for its localisation during meiosis, we created a strain containing the myo51-mCherry allele together with ...
Full article - Journal of Integrative Bioinformatics
... McAdams and Arkin, 1997; Ozbudak et al., 2002; Thattai and van Oudenaarden, 2001]. Many have proposed that cells exploit stochastic, “all-or-none,” effects as a means to achieve genetic and nongenetic diversity within cell populations in order to survive in different environments. Stochastic mechani ...
... McAdams and Arkin, 1997; Ozbudak et al., 2002; Thattai and van Oudenaarden, 2001]. Many have proposed that cells exploit stochastic, “all-or-none,” effects as a means to achieve genetic and nongenetic diversity within cell populations in order to survive in different environments. Stochastic mechani ...
Roles of 14-3-3 and calmodulin binding in subcellular localization
... with kir/Gem and Rad via their C-terminal extensions in a Ca2+ dependent manner [15,16]. CaM inhibits binding of GTP by kir/Gem [15] and shows a better affinity for the GDP-bound form of Rad [16]. The role of CaM binding on RGK family function is unclear, but in the case of kir/Gem may involve the c ...
... with kir/Gem and Rad via their C-terminal extensions in a Ca2+ dependent manner [15,16]. CaM inhibits binding of GTP by kir/Gem [15] and shows a better affinity for the GDP-bound form of Rad [16]. The role of CaM binding on RGK family function is unclear, but in the case of kir/Gem may involve the c ...
Mitochondrial debris reduce viability of healthy cardiomyocytes
... Background: Acute myocardial infarction results in necrosis and initiation of sterile inflammation activated by Damage-Associated Molecular Patterns (DAMPs).Mitochondria are of bacterial origin, displaying bacterial traits in their DNA and proteins. Moreover, the cardiomyocyte volume consists of 30% ...
... Background: Acute myocardial infarction results in necrosis and initiation of sterile inflammation activated by Damage-Associated Molecular Patterns (DAMPs).Mitochondria are of bacterial origin, displaying bacterial traits in their DNA and proteins. Moreover, the cardiomyocyte volume consists of 30% ...
Plk4/SAK/ZYG-1 in the regulation of centriole
... Active Plk4/SAK kinase is present at duplicating mother centrioles during G1/S and the protein levels increase at both centrioles into mitosis [29]. In addition to centriole localization, Plk4/SAK protein levels are regulated and, when aberrant, centriole assembly is either amplified or decreased co ...
... Active Plk4/SAK kinase is present at duplicating mother centrioles during G1/S and the protein levels increase at both centrioles into mitosis [29]. In addition to centriole localization, Plk4/SAK protein levels are regulated and, when aberrant, centriole assembly is either amplified or decreased co ...
Emerging roles for lipids in non-apoptotic cell death
... to cause the release of intracellular contents, loss of ionic homeostasis, and cellular rupture.41 PIPs, including PI(5)P and PI(4,5)P2, are required for MLKL membrane targeting, as liposomes containing only PIs, but not PIPs, do not exhibit MLKL-dependent leakage.41 Interestingly, specific MLKL mut ...
... to cause the release of intracellular contents, loss of ionic homeostasis, and cellular rupture.41 PIPs, including PI(5)P and PI(4,5)P2, are required for MLKL membrane targeting, as liposomes containing only PIs, but not PIPs, do not exhibit MLKL-dependent leakage.41 Interestingly, specific MLKL mut ...
Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication (replication) that produces two daughter cells. In prokaryotes which lack a cell nucleus, the cell cycle occurs via a process termed binary fission. In cells with a nucleus, as in eukaryotes, the cell cycle can be divided into three periods: interphase, the mitotic (M) phase, and cytokinesis. During interphase, the cell grows, accumulating nutrients needed for mitosis, preparing it for cell division and duplicating its DNA. During the mitotic phase, the cell splits itself into two distinct daughter cells. During the final stage, cytokinesis, the new cell is completely divided. To ensure the proper division of the cell, there are control mechanisms known as cell cycle checkpoints.The cell-division cycle is a vital process by which a single-celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. After cell division, each of the daughter cells begin the interphase of a new cycle. Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell division.