Comparative Biochemistry of the Oxidative Burst Produced by Rose
... of the relationship is unclear. Free radical oxidation of plasma membrane lipids, induced by ROS, may kill cells directly. Alternatively, superoxide (Jabs et al., 1996) or H2O2 (Levine et al., 1994) may serve as signals leading indirectly to mortality. However, in at least one case it has been shown ...
... of the relationship is unclear. Free radical oxidation of plasma membrane lipids, induced by ROS, may kill cells directly. Alternatively, superoxide (Jabs et al., 1996) or H2O2 (Levine et al., 1994) may serve as signals leading indirectly to mortality. However, in at least one case it has been shown ...
Modernizing the nonhomologous end-joining repertoire: alternative
... which are members of the poly(ADP-ribose) polymerase (PARP) family (32). DNA-PK and ATM are activated by DSBs, whereas ATR is recruited to stalled replication forks. ATM and the MRE11 complex (consisting of three proteins: MRE11, NBS1, and RAD50) are key players early in DDRs, and an intricate cross ...
... which are members of the poly(ADP-ribose) polymerase (PARP) family (32). DNA-PK and ATM are activated by DSBs, whereas ATR is recruited to stalled replication forks. ATM and the MRE11 complex (consisting of three proteins: MRE11, NBS1, and RAD50) are key players early in DDRs, and an intricate cross ...
PDF Print - APS Journals
... interaction, respectively. At a molecular level, pathogen components (pathogen or microbe-associated molecular patterns, PAMPs or MAMPs) are recognized by the host as nonself to initiate PAMP-triggered immunity (PTI) (Jones and Dangl 2006). Conversely, if the plant species is susceptible to a partic ...
... interaction, respectively. At a molecular level, pathogen components (pathogen or microbe-associated molecular patterns, PAMPs or MAMPs) are recognized by the host as nonself to initiate PAMP-triggered immunity (PTI) (Jones and Dangl 2006). Conversely, if the plant species is susceptible to a partic ...
Document
... Greece, the presentation of the yeast chromosome III and the first 100 kb of the Bacillus subtilis genome revealed that, contrary to expectation (the only cases where this had been observed were phages, for obvious reasons), at least half of the genes uncovered were totally unknown, whether in struc ...
... Greece, the presentation of the yeast chromosome III and the first 100 kb of the Bacillus subtilis genome revealed that, contrary to expectation (the only cases where this had been observed were phages, for obvious reasons), at least half of the genes uncovered were totally unknown, whether in struc ...
Differential expression and regulation of two distinct
... members of the FGF receptor superfamily. The deduced amino acid sequence of PFR1 is 85% identical overall with the human fms-like-gene (FLG). PFR4 is most closely related to the human FGFR-4 (66% overall identity). The tyrosine kinase catalytic domains of both receptors are remarkably conserved. The ...
... members of the FGF receptor superfamily. The deduced amino acid sequence of PFR1 is 85% identical overall with the human fms-like-gene (FLG). PFR4 is most closely related to the human FGFR-4 (66% overall identity). The tyrosine kinase catalytic domains of both receptors are remarkably conserved. The ...
Protein Homeostasis and the Phenotypic - Lindquist Lab
... large, redundancy appears to be provided by unrelated genes that are part of the same or a compensatory biochemical pathway (66, 70, 78, 176). This is also supported by the most comprehensive systematic profiling study of yeast deletion mutants (74). When a large number of growth conditions are assa ...
... large, redundancy appears to be provided by unrelated genes that are part of the same or a compensatory biochemical pathway (66, 70, 78, 176). This is also supported by the most comprehensive systematic profiling study of yeast deletion mutants (74). When a large number of growth conditions are assa ...
Splenic Epstein-Barr Virus–Associated Inflammatory Pseudotumor
... been reported positive in this tumor are clusterin, CNA.42, c-synuclein, and D2-40.4,5,8,15 In most studies CD35 appears to be the most sensitive and reliable marker for this tumor.8,12,16 The spindle cells are often also positive for smooth muscle actin (SMA), but negative for desmin, caldesmon, CD ...
... been reported positive in this tumor are clusterin, CNA.42, c-synuclein, and D2-40.4,5,8,15 In most studies CD35 appears to be the most sensitive and reliable marker for this tumor.8,12,16 The spindle cells are often also positive for smooth muscle actin (SMA), but negative for desmin, caldesmon, CD ...
2) A dynamic cell adhesion surface regulates tissue architecture in
... of skeletal morphogenesis by signaling pathways, the integration of specific cellular processes and matrix structure to generate growth vectors and tissue architecture is not well understood. In the development of long bones, these processes are united in the growth plate cartilage, a unique structu ...
... of skeletal morphogenesis by signaling pathways, the integration of specific cellular processes and matrix structure to generate growth vectors and tissue architecture is not well understood. In the development of long bones, these processes are united in the growth plate cartilage, a unique structu ...
Review Form - Saddleback College
... channels lies well above the wild type’s curve showing that SK2 mutant channels are much more favorable when the drug is administered (Figure 2). SK2 mutant channels show more binding to the drug where as the wild type SK2 channels do not show nearly as much binding (Figure 3). The concentration nee ...
... channels lies well above the wild type’s curve showing that SK2 mutant channels are much more favorable when the drug is administered (Figure 2). SK2 mutant channels show more binding to the drug where as the wild type SK2 channels do not show nearly as much binding (Figure 3). The concentration nee ...
Drosophila Importin-a2 Is Involved in Synapse, Axon and Muscle
... There are three evolutionary clades of Importin-a homologues and each is singly represented in the Drosophila genome [4,14]. All three homologues are required for proper development of male and female germline tissue [15,16,17,18,19,20]. In addition, they function outside of the germline: importin-a ...
... There are three evolutionary clades of Importin-a homologues and each is singly represented in the Drosophila genome [4,14]. All three homologues are required for proper development of male and female germline tissue [15,16,17,18,19,20]. In addition, they function outside of the germline: importin-a ...
Treatment of experimental arthritis by inducing immune tolerance
... Mesenchymal stem cells (MSCs) are mesodermderived cells that reside in the stroma of solid organs and function as precursors of nonhematopoietic connective tissues. Besides their capacity to differentiate into mesenchymal and nonmesenchymal cell lineages (7,8) and their potential clinical applicatio ...
... Mesenchymal stem cells (MSCs) are mesodermderived cells that reside in the stroma of solid organs and function as precursors of nonhematopoietic connective tissues. Besides their capacity to differentiate into mesenchymal and nonmesenchymal cell lineages (7,8) and their potential clinical applicatio ...
Functions and Mechanisms of Fibroblast Growth Factor (FGF
... ligands (Pyramus (Pyr), Thisbe (Ths) and Branchless (Bnl)) that can combine into three functional interactions of FGFR/FGF-ligand pairs: Htl/Pyr, Htl/Ths and Btl/Bnl. In contrast, in humans presumably more than 70 FGFR/FGF combinations are generated by four FGFRs and 22 FGF ligands, respectively; al ...
... ligands (Pyramus (Pyr), Thisbe (Ths) and Branchless (Bnl)) that can combine into three functional interactions of FGFR/FGF-ligand pairs: Htl/Pyr, Htl/Ths and Btl/Bnl. In contrast, in humans presumably more than 70 FGFR/FGF combinations are generated by four FGFRs and 22 FGF ligands, respectively; al ...
Regulation of Vascular Development - Size
... hypothesis predicts that cells would be added incrementally to the end of developing procambial strands, but these observations suggest that this step happens at a prepatterning stage and that morphological appearance of procambium is expressed only after the bridge from auxin source to sink is comp ...
... hypothesis predicts that cells would be added incrementally to the end of developing procambial strands, but these observations suggest that this step happens at a prepatterning stage and that morphological appearance of procambium is expressed only after the bridge from auxin source to sink is comp ...
Chapter_01
... ultrastructural organelle consisting of membrane-bound cavities in the cytoplasm of the cell ER function: Transports substances in the cytoplasm Golgi apparatus or Golgi complex are critical for post-translational modifications that help sort, condense, package, and deliver proteins arriving from th ...
... ultrastructural organelle consisting of membrane-bound cavities in the cytoplasm of the cell ER function: Transports substances in the cytoplasm Golgi apparatus or Golgi complex are critical for post-translational modifications that help sort, condense, package, and deliver proteins arriving from th ...
Pea3 Transcription Factor Family Members Etv4 and Etv5 Mediate
... innervation. Real-time PCR assays indicated that Etv4 and Etv5 mRNAs are significantly induced by NGF in different neuronal cells, suggesting that they could be involved in the biological responses induced by this neurotrophin. Interestingly, distal axon application of NGF in compartmentalized cultu ...
... innervation. Real-time PCR assays indicated that Etv4 and Etv5 mRNAs are significantly induced by NGF in different neuronal cells, suggesting that they could be involved in the biological responses induced by this neurotrophin. Interestingly, distal axon application of NGF in compartmentalized cultu ...
Transcriptional mechanisms regulating skeletal muscle
... From numerous studies, it is clear that sonic hedgehog (SHH) and WNT signalling have pivotal roles in the induction of myogenesis. Moreover, other signalling molecules, such as Noggin and bone morphogenetic proteins (BMPs) — which inactivate and activate receptors of the transforming growth factor-β ...
... From numerous studies, it is clear that sonic hedgehog (SHH) and WNT signalling have pivotal roles in the induction of myogenesis. Moreover, other signalling molecules, such as Noggin and bone morphogenetic proteins (BMPs) — which inactivate and activate receptors of the transforming growth factor-β ...
Recurrent Gene Duplication Diversifies Genome
... inviability (Klattenhoff et al. 2009). We previously showed that HP1D/Rhino evolves under strong positive selection, consistent with its role in a genetic conflict with TEs (Vermaak et al. 2005). We also previously discovered a few partial or complete HP1D/Rhino paralogs in a phylogenomic survey of ...
... inviability (Klattenhoff et al. 2009). We previously showed that HP1D/Rhino evolves under strong positive selection, consistent with its role in a genetic conflict with TEs (Vermaak et al. 2005). We also previously discovered a few partial or complete HP1D/Rhino paralogs in a phylogenomic survey of ...
Development of Conjunctival Goblet Cells and Their
... bound strongly to single goblet cells and goblet cell clusters. At 60 days old, all the goblet cell clusters reacted with UEA-I, although the pattern (shape and density) of staining varied between clusters. Minimal binding of UEA-I was observed in the stroma or in the stratified squamous cells at th ...
... bound strongly to single goblet cells and goblet cell clusters. At 60 days old, all the goblet cell clusters reacted with UEA-I, although the pattern (shape and density) of staining varied between clusters. Minimal binding of UEA-I was observed in the stroma or in the stratified squamous cells at th ...
- Columbia University Medical Center
... of HH results from an activity inherent in the carboxyterminal domain of the precursor protein, and mutations in the carboxy-terminal domain that impair cleavage severely attenuate the normal patterning activities of HH in Drosophila development (Lee et al., 1994; Porter et al., 1995). Autoproteolyt ...
... of HH results from an activity inherent in the carboxyterminal domain of the precursor protein, and mutations in the carboxy-terminal domain that impair cleavage severely attenuate the normal patterning activities of HH in Drosophila development (Lee et al., 1994; Porter et al., 1995). Autoproteolyt ...
MaxiK Channel β-Subunits
... substances (8, 17). All of these modulatory mechanisms allow fast integration of multiple stimuli in many tissues, including neurons, VSMCs, and cochlear hair cells. The Drosophila ,subunit (dSlo) can interact with two different accessory proteins, known as dSlip1 and Slob. Both are soluble proteins ...
... substances (8, 17). All of these modulatory mechanisms allow fast integration of multiple stimuli in many tissues, including neurons, VSMCs, and cochlear hair cells. The Drosophila ,subunit (dSlo) can interact with two different accessory proteins, known as dSlip1 and Slob. Both are soluble proteins ...
Role of E-cadherin and other cell adhesion molecules in survival
... cadherin-type repeats (extracellular cadherin domains) that are bound together by Ca2+ ions. The cytoplasmic tails of E-cadherin bind to p120-catenin (p120) and b-catenin (b-cat), while b-catenin binds to monomeric a-catenin (a-cat) which indirectly anchors the cadherin-catenin complexes to the acti ...
... cadherin-type repeats (extracellular cadherin domains) that are bound together by Ca2+ ions. The cytoplasmic tails of E-cadherin bind to p120-catenin (p120) and b-catenin (b-cat), while b-catenin binds to monomeric a-catenin (a-cat) which indirectly anchors the cadherin-catenin complexes to the acti ...
d-glucose-sensitive neurosecretory cells of the crab cancer borealis
... In all these experiments, the substances were injected into the bloodstream of intact or eyestalkless animals and the glucose level was measured. The reported results vary for different species, and the cellular pathways mediating these responses remain unclear. In this study, we have examined the d ...
... In all these experiments, the substances were injected into the bloodstream of intact or eyestalkless animals and the glucose level was measured. The reported results vary for different species, and the cellular pathways mediating these responses remain unclear. In this study, we have examined the d ...
PDF
... 1996; Thomas and Schneider, 2011; Urrutia, 2003). KAP1 has previously been demonstrated to maintain ERVs in a silent state in embryonic stem (ES) cells via the histone methyltransferase ESET (also known as SETDB1) and secondary H3K9 trimethylation (Matsui et al., 2010; Rowe et al., 2010). It is also ...
... 1996; Thomas and Schneider, 2011; Urrutia, 2003). KAP1 has previously been demonstrated to maintain ERVs in a silent state in embryonic stem (ES) cells via the histone methyltransferase ESET (also known as SETDB1) and secondary H3K9 trimethylation (Matsui et al., 2010; Rowe et al., 2010). It is also ...
Minimal Time Requirement for Lasting Elicitor Effects in
... Amino acid uptake into plant cells is known to proceed via proton cotransport [30] and to depend on carriers [31, 32] as well as on the plasmalemma potential and its ATPase activity [33]. Plant cells may also possess additional regulatory systems for amino acid homeostasis [33, 34], W hen parsley ce ...
... Amino acid uptake into plant cells is known to proceed via proton cotransport [30] and to depend on carriers [31, 32] as well as on the plasmalemma potential and its ATPase activity [33]. Plant cells may also possess additional regulatory systems for amino acid homeostasis [33, 34], W hen parsley ce ...
D:\ACTA\3-2003\jozwiak 732.vp
... Laboratoire Roger Bellon (France). Eagle’s Minimal Essential Medium was from the Sera and Vaccines Factory (Lublin, Poland), calf serum and lactalbumin hydrolysate were from Gibco BRL (Scotland). Gentamicin was purchased from Biochemie Gesellschaft m.b.H (Vienna, Austria). All other chemicals and so ...
... Laboratoire Roger Bellon (France). Eagle’s Minimal Essential Medium was from the Sera and Vaccines Factory (Lublin, Poland), calf serum and lactalbumin hydrolysate were from Gibco BRL (Scotland). Gentamicin was purchased from Biochemie Gesellschaft m.b.H (Vienna, Austria). All other chemicals and so ...