A Role for Eosinophils in Adaptive Humoral Immunity
... interleukins, chemokines and RNAses (collectively known as eokines), which can be rapidly released during an inflammatory response to foreign proteins. Their accumulation and release of diverse eokines during the inflammation that accompanies an anamnestic response suggests an immunoregulatory funct ...
... interleukins, chemokines and RNAses (collectively known as eokines), which can be rapidly released during an inflammatory response to foreign proteins. Their accumulation and release of diverse eokines during the inflammation that accompanies an anamnestic response suggests an immunoregulatory funct ...
PGC specification from epiblast
... Primordial germ cells (PGCs) in mice have been recognized histologically as alkaline phosphatase (AP) activity-positive cells at 7.2 days post coitum (dpc) in the extra-embryonic mesoderm. However, mechanisms regulating PGC formation are unknown, and an appropriate in vitro system to study the mecha ...
... Primordial germ cells (PGCs) in mice have been recognized histologically as alkaline phosphatase (AP) activity-positive cells at 7.2 days post coitum (dpc) in the extra-embryonic mesoderm. However, mechanisms regulating PGC formation are unknown, and an appropriate in vitro system to study the mecha ...
figure 2 - Open Biology
... Figure 2. Single-cell clustering. (a) Average silhouette value for different numbers of clusters using Gaussian mixture modelling (GMM) and hierarchical clustering. Higher averages represent better cluster quality, and the best clustering for this dataset was reached when cells were grouped into sev ...
... Figure 2. Single-cell clustering. (a) Average silhouette value for different numbers of clusters using Gaussian mixture modelling (GMM) and hierarchical clustering. Higher averages represent better cluster quality, and the best clustering for this dataset was reached when cells were grouped into sev ...
Cell signalling - The Open University
... cells of the opposite mating type. It does this by secreting a ‘mating factor’ peptide, an extracellular signal, which can also be called an ‘intercellular signal’. Yeast mating factor binds to specific cell surface receptors on cells of the opposite mating type, and the signal is relayed into the t ...
... cells of the opposite mating type. It does this by secreting a ‘mating factor’ peptide, an extracellular signal, which can also be called an ‘intercellular signal’. Yeast mating factor binds to specific cell surface receptors on cells of the opposite mating type, and the signal is relayed into the t ...
Similarities and Differences in the Glycosylation Mechanisms in
... in the “paradigm” organism, C. jejuni, Aebi, and coworkers have shown that PglK (previously called wlaB), which is an ABC-type transporter, is responsible for flipping the LLO [14]. Interestingly, these workers found that PglK has a relaxed substrate specificity exemplified by its ability to complem ...
... in the “paradigm” organism, C. jejuni, Aebi, and coworkers have shown that PglK (previously called wlaB), which is an ABC-type transporter, is responsible for flipping the LLO [14]. Interestingly, these workers found that PglK has a relaxed substrate specificity exemplified by its ability to complem ...
Progressive lineage analysis by cell sorting and culture identifies
... Fig. 2 presents the shift of surface marker expression during 4 days of ES cell culture under this condition. ES cells maintained with LIF in gelatin-coated dishes expressed high levels of E-cadherin but not FLK-1 or PDGFRα (Fig. 2A). After transferring them to type IV collagen-coated dishes and cul ...
... Fig. 2 presents the shift of surface marker expression during 4 days of ES cell culture under this condition. ES cells maintained with LIF in gelatin-coated dishes expressed high levels of E-cadherin but not FLK-1 or PDGFRα (Fig. 2A). After transferring them to type IV collagen-coated dishes and cul ...
Electrocardioqraphic criteria for predicting the site of coronary artery
... and virulence factors in these organisms. Plasmid-free strains of Enterococcus faecalis secrete at least half a dozen peptide sex pheromone-probably many more-that induce a mating response by potential donor strains carrying members of specific families of conjugative plasmids. The response is assoc ...
... and virulence factors in these organisms. Plasmid-free strains of Enterococcus faecalis secrete at least half a dozen peptide sex pheromone-probably many more-that induce a mating response by potential donor strains carrying members of specific families of conjugative plasmids. The response is assoc ...
Uptake of extracellular DNA: Competence induced pili in natural
... uptake proteins reside. In Bacillus subtilis biochemical data suggested that the major pseudopilin ComGC is able to assemble into a polymeric structure that is essential for transformation; however, no such structure had been visualized [7]. Recently, Laurenceau and co-workers described a type IV li ...
... uptake proteins reside. In Bacillus subtilis biochemical data suggested that the major pseudopilin ComGC is able to assemble into a polymeric structure that is essential for transformation; however, no such structure had been visualized [7]. Recently, Laurenceau and co-workers described a type IV li ...
Detection of Viable but Nonculturable Cells of Listeria
... importance is connected with VBNC cell existence and, consequently, their ability to retain virulence. L. monocytogenes is a bacterium with the ability to enter the VBNC state (Oliver 2005a). What is more, it appears that L. monocytogenes VBNC cells are more tolerant to stresses than growing cells ( ...
... importance is connected with VBNC cell existence and, consequently, their ability to retain virulence. L. monocytogenes is a bacterium with the ability to enter the VBNC state (Oliver 2005a). What is more, it appears that L. monocytogenes VBNC cells are more tolerant to stresses than growing cells ( ...
Spatial Relationship between Transcription Sites and Chromosome
... the interior of chromosome territories. Furthermore, several coding genes were found positioned preferentially at the periphery of chromosome territories. Apparently, this configuration was independent of the transcriptional activ- ...
... the interior of chromosome territories. Furthermore, several coding genes were found positioned preferentially at the periphery of chromosome territories. Apparently, this configuration was independent of the transcriptional activ- ...
RADIOACTIVE PHOSPHORUS IN STUDIES ON THE
... equal to that initially present, i.e., an amount sufficient to form another nucleus. This was in approximate agreement with data on rate of growth of the tumor from which it was estimated that its weight was doubled in 24 hours (21). Brues et al. (25) found that between three and eight days after p3 ...
... equal to that initially present, i.e., an amount sufficient to form another nucleus. This was in approximate agreement with data on rate of growth of the tumor from which it was estimated that its weight was doubled in 24 hours (21). Brues et al. (25) found that between three and eight days after p3 ...
Targeting of Active Sialyltransferase to the Plant Golgi Apparatus
... T.A. Prime, D.J. Sherrier, and P. Dupree, unpublished data). Callus lines were induced from the transgenic plants and maintained in liquid culture. Transit of ST through the secretory pathway in the callus cells was investigated by endo-b-N-acetylglucosaminidase H (Endo H) digestion of proteins. Thi ...
... T.A. Prime, D.J. Sherrier, and P. Dupree, unpublished data). Callus lines were induced from the transgenic plants and maintained in liquid culture. Transit of ST through the secretory pathway in the callus cells was investigated by endo-b-N-acetylglucosaminidase H (Endo H) digestion of proteins. Thi ...
Glucocorticoids Regulate Pituitary Growth Hormone
... mRNA expression in vivo. Total RNA (2.5 mg) isolated from individual pituitaries of sham-operated or bilaterally adrenalectomized rats treated with cholesterol or corticosterone for 3 days was analyzed by RT-PCR for amounts of GHRH-R (panel A) and RPL19 (panel B) mRNAs. Autoradiograms of the dried 5 ...
... mRNA expression in vivo. Total RNA (2.5 mg) isolated from individual pituitaries of sham-operated or bilaterally adrenalectomized rats treated with cholesterol or corticosterone for 3 days was analyzed by RT-PCR for amounts of GHRH-R (panel A) and RPL19 (panel B) mRNAs. Autoradiograms of the dried 5 ...
Synergistic interaction between C5a and NOD2 signaling
... and/or tissue injury. While individual signaling pathways for PRRs and complement are relatively well understood, the complex interactions between these different arms of the innate immune response have been less well studied. Proteolysis of C5 is one of the key events of complement activation, gene ...
... and/or tissue injury. While individual signaling pathways for PRRs and complement are relatively well understood, the complex interactions between these different arms of the innate immune response have been less well studied. Proteolysis of C5 is one of the key events of complement activation, gene ...
Asymmetric Cell Division as a Route to Reduction in Cell Length
... SCC1 from the beginning of S-phase until anaphase. Homologues of the four components of cohesin were identified in the Trypanosoma brucei genome sequence and a functional analysis of the trypanosome SCC1 demonstrated that it is the orthologue of yeast SCC1 (Gluenz, Sharma, Gull ...
... SCC1 from the beginning of S-phase until anaphase. Homologues of the four components of cohesin were identified in the Trypanosoma brucei genome sequence and a functional analysis of the trypanosome SCC1 demonstrated that it is the orthologue of yeast SCC1 (Gluenz, Sharma, Gull ...
Journal of Plant Growth Regulation
... associated with the apical surfaces of the host crypt cells, throughout the life history of the host (Figure 2C). Studies with V. fischeri mutants that are defective in motility (Graf and others 1994) indicate that, although they aggregate, they do not leave the matrix to colonize host tissues. In a ...
... associated with the apical surfaces of the host crypt cells, throughout the life history of the host (Figure 2C). Studies with V. fischeri mutants that are defective in motility (Graf and others 1994) indicate that, although they aggregate, they do not leave the matrix to colonize host tissues. In a ...
A novel live cell assay to measure diacylglycerol lipase α activity
... processes including axonal growth and guidance, adult neurogenesis and retrograde signalling at the synapse. Recent studies have implicated DAGLα as an emerging drug target for several conditions including pain and obesity. Activity assays are critical to the drug discovery process; however, measure ...
... processes including axonal growth and guidance, adult neurogenesis and retrograde signalling at the synapse. Recent studies have implicated DAGLα as an emerging drug target for several conditions including pain and obesity. Activity assays are critical to the drug discovery process; however, measure ...
Effect of Steroid Hormones and Retinoids on the Formation of
... and the formation of capillary-like tubular structures (‘‘tube formation’’) of endothelial cells in the three-dimensional fibrin matrix were analyzed by phase contrast microscopy and the total number, the total area, and the total length of capillary-like tubular structures of six randomly chosen mi ...
... and the formation of capillary-like tubular structures (‘‘tube formation’’) of endothelial cells in the three-dimensional fibrin matrix were analyzed by phase contrast microscopy and the total number, the total area, and the total length of capillary-like tubular structures of six randomly chosen mi ...
Dynamic properties of a reconstituted myelin sheath
... unstructured protein in solution [12,21]. P2 is a small folded protein with a high homology to members of the fatty acid binding protein family [7,18]. It is expressed in the cytoplasmic face of compact myelin in the PNS [9,27], and its lipid-binding activity suggests it may serve important function ...
... unstructured protein in solution [12,21]. P2 is a small folded protein with a high homology to members of the fatty acid binding protein family [7,18]. It is expressed in the cytoplasmic face of compact myelin in the PNS [9,27], and its lipid-binding activity suggests it may serve important function ...
Fibronectins Are Essential for Heart and Blood Vessel
... the primitive heart. In the more severe class, no primitive heart is detectable in whole-mount analysis. In contrast, the less severely affected embryos display a prominent primitive heart, and beating is detectable during dissection. Differences in severity also occur in the degree of shortening of ...
... the primitive heart. In the more severe class, no primitive heart is detectable in whole-mount analysis. In contrast, the less severely affected embryos display a prominent primitive heart, and beating is detectable during dissection. Differences in severity also occur in the degree of shortening of ...
Lysosomal Heterogeneity in Exocrine Acinar Cells
... are characterized by the presence of trimetaphosphatase activity (TMPase) (Figure 2). Nonspecific esterase and aryl sulfatase B activities have also been demonstrated in these lysosomes (6). TMPase, esterase, and aryl sulfatase activities can also be localized in lysosomes adjacent to the Golgi appa ...
... are characterized by the presence of trimetaphosphatase activity (TMPase) (Figure 2). Nonspecific esterase and aryl sulfatase B activities have also been demonstrated in these lysosomes (6). TMPase, esterase, and aryl sulfatase activities can also be localized in lysosomes adjacent to the Golgi appa ...
New beginnings in studies of eukaryotic DNA replication
... 458 and 6855), Bgl (B at 1288). and Mlul (M at 3877). (B) Schematic diagram of the replication of seveBai repeat units. ARS elements and 37 S transcription are indicated as in section (A). This figure is modified from [13]. See text for further details. ...
... 458 and 6855), Bgl (B at 1288). and Mlul (M at 3877). (B) Schematic diagram of the replication of seveBai repeat units. ARS elements and 37 S transcription are indicated as in section (A). This figure is modified from [13]. See text for further details. ...
Lecture 16 - Gene Transcription and Translation
... years ago led to the creation of enhancers and exons for a gene responsible for neurodevelopment, ISL1. ISL1 plays a hugely important role in regulating insulin gene expression, governs motor neuron generation, and helps the development of a bilateral heart in mammals. “These add to a growing list o ...
... years ago led to the creation of enhancers and exons for a gene responsible for neurodevelopment, ISL1. ISL1 plays a hugely important role in regulating insulin gene expression, governs motor neuron generation, and helps the development of a bilateral heart in mammals. “These add to a growing list o ...
Comparative Biochemistry of the Oxidative Burst Produced by Rose
... of the relationship is unclear. Free radical oxidation of plasma membrane lipids, induced by ROS, may kill cells directly. Alternatively, superoxide (Jabs et al., 1996) or H2O2 (Levine et al., 1994) may serve as signals leading indirectly to mortality. However, in at least one case it has been shown ...
... of the relationship is unclear. Free radical oxidation of plasma membrane lipids, induced by ROS, may kill cells directly. Alternatively, superoxide (Jabs et al., 1996) or H2O2 (Levine et al., 1994) may serve as signals leading indirectly to mortality. However, in at least one case it has been shown ...