Ligation of tumour-produced mucins to CD22 dramatically impairs
... CD22, a member of the Siglec (sialic acid-binding, immunoglobulin-like lectin) family, is a B-cell-specific glycoprotein that associates with the BCR (B-cell receptor). It is generally agreed that CD22 must be in close proximity to the BCR complex for negative regulation of signalling through recrui ...
... CD22, a member of the Siglec (sialic acid-binding, immunoglobulin-like lectin) family, is a B-cell-specific glycoprotein that associates with the BCR (B-cell receptor). It is generally agreed that CD22 must be in close proximity to the BCR complex for negative regulation of signalling through recrui ...
Cell Research
... 30 h after germination. Unlike most PIPs, whose expression peaked before radicle emergence and declined immediately afterwards, the levels of OsPIP2;2 and OsPIP2;6 www.cell-research.com | Cell Research ...
... 30 h after germination. Unlike most PIPs, whose expression peaked before radicle emergence and declined immediately afterwards, the levels of OsPIP2;2 and OsPIP2;6 www.cell-research.com | Cell Research ...
Identification and characterization of regulatory factors and
... 3.1.3 YmoA regulates CsrC synthesis independently of CsrB ........................................65 3.1.4 YmoA influences CsrC RNA stability ..................................................................68 3.1.5 CsrC RNA stability in Y. pseudotuberculosis is affected by YmoA in a CsrA-inde ...
... 3.1.3 YmoA regulates CsrC synthesis independently of CsrB ........................................65 3.1.4 YmoA influences CsrC RNA stability ..................................................................68 3.1.5 CsrC RNA stability in Y. pseudotuberculosis is affected by YmoA in a CsrA-inde ...
4 | the tissue level of organization
... The zygote, or fertilized egg, is a single cell formed by the fusion of an egg and sperm. After fertilization the zygote gives rise to rapid mitotic cycles, generating many cells to form the embryo. The first embryonic cells generated have the ability to differentiate into any type of cell in the bo ...
... The zygote, or fertilized egg, is a single cell formed by the fusion of an egg and sperm. After fertilization the zygote gives rise to rapid mitotic cycles, generating many cells to form the embryo. The first embryonic cells generated have the ability to differentiate into any type of cell in the bo ...
Gap Junctional Communication in the Extraembryonic Tissues of the
... Figure 4. Dye coupling in other regions of the EPC. A, Restriction in dye coupling in the upper peripheral region of the EPC (EPC-U). An impalement into the upper peripheral region of the EPC (a) revealed a pattern of limited Lucifer yellow spread, with dye filling only a cluster of cells in the up ...
... Figure 4. Dye coupling in other regions of the EPC. A, Restriction in dye coupling in the upper peripheral region of the EPC (EPC-U). An impalement into the upper peripheral region of the EPC (a) revealed a pattern of limited Lucifer yellow spread, with dye filling only a cluster of cells in the up ...
Anti-bacteria and In Vivo Tumor Treatment by Reactive Oxygen
... were cultured in DMEM supplemented with 10% FBS at 37 °C in a humified atmosphere containing 5% CO2. And then the cells were seeded in 96-well plates at a density of 1×105 cells per well at different pH values (pH = 5.5, 6.8 and 7.4). After 15 h adhesion, the 6-nm MNPs was added into the medium and ...
... were cultured in DMEM supplemented with 10% FBS at 37 °C in a humified atmosphere containing 5% CO2. And then the cells were seeded in 96-well plates at a density of 1×105 cells per well at different pH values (pH = 5.5, 6.8 and 7.4). After 15 h adhesion, the 6-nm MNPs was added into the medium and ...
Combinatorial Gli gene function in floor plate and
... expression of HNF-3β within the neural tube (Fig. 3B,C; Table 1B,D). Neither injection of Gli2 nor Gli3 resulted in ectopic HNF-3β expression (Table 1B,D; Lee et al., 1997). These results show that Gli proteins have non-redundant functions as only Gli1 can induce floor plate differentiation. Gli pro ...
... expression of HNF-3β within the neural tube (Fig. 3B,C; Table 1B,D). Neither injection of Gli2 nor Gli3 resulted in ectopic HNF-3β expression (Table 1B,D; Lee et al., 1997). These results show that Gli proteins have non-redundant functions as only Gli1 can induce floor plate differentiation. Gli pro ...
Cardiomyocyte Lineage Specification in€Adult Human Cardiac
... The mechanisms controlling differentiation in adult cardiac precursor cells (CPCs) are still largely unknown. In this study, CPCs isolated from the human heart were found to produce predominantly smooth muscle cells but could be redirected to the cardiomyocyte fate by transient activation followed b ...
... The mechanisms controlling differentiation in adult cardiac precursor cells (CPCs) are still largely unknown. In this study, CPCs isolated from the human heart were found to produce predominantly smooth muscle cells but could be redirected to the cardiomyocyte fate by transient activation followed b ...
Arabinogalactan proteins are involved in root hair development in
... The reactive form, containing β-D-glucosyl residues (βGlcY), is capable of binding and/or precipitating AGPs (Yariv et al., 1962). Plants or organs treated with a Yariv reagent are deprived of functional AGPs naturally present on their surface, which allows their functional investigation in vivo. Ho ...
... The reactive form, containing β-D-glucosyl residues (βGlcY), is capable of binding and/or precipitating AGPs (Yariv et al., 1962). Plants or organs treated with a Yariv reagent are deprived of functional AGPs naturally present on their surface, which allows their functional investigation in vivo. Ho ...
Phylogenetic analysis of spotted fever group rickettsiae by study of
... Rickettsiae are classified in the order Rickettsiales and have been included in the a subclass of the class Proteobacteria on the basis of 165 rRNA gene sequence comparison. T o estimate the evolutionary forces that have shaped the members of the spotted fever group (SFG) rickettsiae, t h e ompA gen ...
... Rickettsiae are classified in the order Rickettsiales and have been included in the a subclass of the class Proteobacteria on the basis of 165 rRNA gene sequence comparison. T o estimate the evolutionary forces that have shaped the members of the spotted fever group (SFG) rickettsiae, t h e ompA gen ...
Evolution of acidocalcisomes and their role in polyphosphate
... (Lu et al. 1998). Physiological experiments in L. donovani also suggested the presence of the V-Hþ-ATPase and the V-Hþ-PPase in different compartments (Rodrigues et al. 1999b). The V-Hþ-PPase also exists elsewhere in some species. It was initially described in chromatophore membranes of Rhodospirill ...
... (Lu et al. 1998). Physiological experiments in L. donovani also suggested the presence of the V-Hþ-ATPase and the V-Hþ-PPase in different compartments (Rodrigues et al. 1999b). The V-Hþ-PPase also exists elsewhere in some species. It was initially described in chromatophore membranes of Rhodospirill ...
Evolution of acidocalcisomes and their role in polyphosphate
... (Lu et al. 1998). Physiological experiments in L. donovani also suggested the presence of the V-Hþ-ATPase and the V-Hþ-PPase in different compartments (Rodrigues et al. 1999b). The V-Hþ-PPase also exists elsewhere in some species. It was initially described in chromatophore membranes of Rhodospirill ...
... (Lu et al. 1998). Physiological experiments in L. donovani also suggested the presence of the V-Hþ-ATPase and the V-Hþ-PPase in different compartments (Rodrigues et al. 1999b). The V-Hþ-PPase also exists elsewhere in some species. It was initially described in chromatophore membranes of Rhodospirill ...
Origin of the zebrafish endocrine and exocrine
... merged (Field et al., 2003; schematized in Fig. 1) to form a single pancreatic islet of endocrine cells, surrounded by exocrine tissue, with the entire structure localized to the right side of the ventral midline. Molecular markers reveal that pancreatic development is well under way at stages that ...
... merged (Field et al., 2003; schematized in Fig. 1) to form a single pancreatic islet of endocrine cells, surrounded by exocrine tissue, with the entire structure localized to the right side of the ventral midline. Molecular markers reveal that pancreatic development is well under way at stages that ...
a va i l a b l e a t... w w w. e l s e v i e...
... Despite recent advancements, the mechanism of Delta cleavage is not completely understood. Drosophila Delta proteolysis produces three distinct cell-associated products termed DlcdP1, DlcdP2 and DlcdP3 [7]. DlcdP1 arises from cleavage in the JM domain by the Kuzbanian (ADAM10) metalloprotease. This ...
... Despite recent advancements, the mechanism of Delta cleavage is not completely understood. Drosophila Delta proteolysis produces three distinct cell-associated products termed DlcdP1, DlcdP2 and DlcdP3 [7]. DlcdP1 arises from cleavage in the JM domain by the Kuzbanian (ADAM10) metalloprotease. This ...
Prox1 and fibroblast growth factor receptors form a
... Tissue morphogenesis requires cell-cell communication, often mediated by growth factors, that reprograms cellular phenotypes. This response is fine-tuned by regulation of growth factor receptor expression, allowing cells to respond to, or ignore, specific stimuli (Cross and Dexter, 1991; Scata et al ...
... Tissue morphogenesis requires cell-cell communication, often mediated by growth factors, that reprograms cellular phenotypes. This response is fine-tuned by regulation of growth factor receptor expression, allowing cells to respond to, or ignore, specific stimuli (Cross and Dexter, 1991; Scata et al ...
The Arabidopsis homeotic genes APETALA3 and PISTILLATA are
... flowers ectopically expressing APETALA3 and PISTILLATA and the rescue of missing organs in class A mutants by ectopic B function suggest that APETALA3 and PISTILLATA play an additional role in proliferation of the floral meristem. ...
... flowers ectopically expressing APETALA3 and PISTILLATA and the rescue of missing organs in class A mutants by ectopic B function suggest that APETALA3 and PISTILLATA play an additional role in proliferation of the floral meristem. ...
A Buoyancy-Based Screen of Drosophila Larvae for Fat
... invertebrates have the potential to identify genes and pathways that regulate the levels of stored fat, many of which are likely to be conserved in humans. To facilitate such screens, we have developed a simple buoyancy-based screening method for identifying mutant Drosophila larvae with increased l ...
... invertebrates have the potential to identify genes and pathways that regulate the levels of stored fat, many of which are likely to be conserved in humans. To facilitate such screens, we have developed a simple buoyancy-based screening method for identifying mutant Drosophila larvae with increased l ...
Notochord vacuoles are lysosome-related organelles that function in
... Department of Cell Biology, Duke University Medical Center, Durham, NC 27710 ...
... Department of Cell Biology, Duke University Medical Center, Durham, NC 27710 ...
Supplementary Data - Institute of Cancer Research
... PGRP-LC isoforms LCa, LCx and LCy 13, 29, 30. This cytosolic tail lacks any obvious endocytic motifs, and no ligand-induced trafficking of the receptor has been reported so far. A closer look at the PGRP-LC locus revealed a potential alternative first coding exon, which might encode a functionally d ...
... PGRP-LC isoforms LCa, LCx and LCy 13, 29, 30. This cytosolic tail lacks any obvious endocytic motifs, and no ligand-induced trafficking of the receptor has been reported so far. A closer look at the PGRP-LC locus revealed a potential alternative first coding exon, which might encode a functionally d ...
Notochord vacuoles are lysosome-related organelles that function in
... work was performed in the same orientation at approximately the same position along the anterior-posterior axis (Fig. 1, D and E). Transgenic membrane GFP (GFP-CaaX) embryos were incubated in the vital dye BODIPY TR methyl ester dye (MED) to visualize internal membranes (Fig. 1, F–H). We observed th ...
... work was performed in the same orientation at approximately the same position along the anterior-posterior axis (Fig. 1, D and E). Transgenic membrane GFP (GFP-CaaX) embryos were incubated in the vital dye BODIPY TR methyl ester dye (MED) to visualize internal membranes (Fig. 1, F–H). We observed th ...
Molecular cloning and characterization of chitinase
... and repressed by glucose. The cells seem to produce several different chitinases simultaneously. A gene for chitinase has been cloned from S. plicatus in E. coli (Robbins et al., 1988). However, our understanding of the regulatory mechanisms that control the synthesis and function of the multiple en ...
... and repressed by glucose. The cells seem to produce several different chitinases simultaneously. A gene for chitinase has been cloned from S. plicatus in E. coli (Robbins et al., 1988). However, our understanding of the regulatory mechanisms that control the synthesis and function of the multiple en ...
Electron Tomographic Analysis of Somatic Cell
... the IMOD package (Mastronarde, 1997; Otegui et al., 2001), one can rotate the vesicle around the axis of the rod-like linker domain to produce a side view that shows an L-shaped complex (Figure 4E). Three corresponding views of the modeled L-shaped complex are shown in Figures 4F to 4H. The axial le ...
... the IMOD package (Mastronarde, 1997; Otegui et al., 2001), one can rotate the vesicle around the axis of the rod-like linker domain to produce a side view that shows an L-shaped complex (Figure 4E). Three corresponding views of the modeled L-shaped complex are shown in Figures 4F to 4H. The axial le ...
Keystone Standards
... BIO.A.2. 1. Describe how the unique properties of water support life on Earth. BIO.A.2. 1.1. Describe the unique properties of water and how these properties support life on Earth (e.g., freezing point, high specific heat, cohesion). BIO.A.2. 2. Describe and interpret relationships between structure ...
... BIO.A.2. 1. Describe how the unique properties of water support life on Earth. BIO.A.2. 1.1. Describe the unique properties of water and how these properties support life on Earth (e.g., freezing point, high specific heat, cohesion). BIO.A.2. 2. Describe and interpret relationships between structure ...
Electron Tomographic Analysis of Somatic Cell Plate Formation in
... the IMOD package (Mastronarde, 1997; Otegui et al., 2001), one can rotate the vesicle around the axis of the rod-like linker domain to produce a side view that shows an L-shaped complex (Figure 4E). Three corresponding views of the modeled L-shaped complex are shown in Figures 4F to 4H. The axial le ...
... the IMOD package (Mastronarde, 1997; Otegui et al., 2001), one can rotate the vesicle around the axis of the rod-like linker domain to produce a side view that shows an L-shaped complex (Figure 4E). Three corresponding views of the modeled L-shaped complex are shown in Figures 4F to 4H. The axial le ...
IJMS 45(10) 1234-1244
... hemocytes detect LPS molecules on their surfaces46, and then release, via rapid exocytosis, the contents of L- and S-granules47. These released granular components include two biosensors, named factors C and G. These two factors are serine protease zymogens and are autocatalytically activated by LPS ...
... hemocytes detect LPS molecules on their surfaces46, and then release, via rapid exocytosis, the contents of L- and S-granules47. These released granular components include two biosensors, named factors C and G. These two factors are serine protease zymogens and are autocatalytically activated by LPS ...