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Lipoprotein Lipase in the Arterial Wall
Lipoprotein Lipase in the Arterial Wall

PHYLUM MOLLUSCA - Formatted
PHYLUM MOLLUSCA - Formatted

... habitats. They live in fresh water pools, ponds, lakes and paddy fields where succulent water plants are in abundant. Sometimes they may be found in running streams also. They are herbivores and aquatic plants like Vallisnaria and Pistia constitutes its food. Pila is a voracious feeder and feeds on ...
The dehydratase ADT3 affects ROS homeostasis
The dehydratase ADT3 affects ROS homeostasis

... addition, adt3-1 cells were hyper-vacuolated (especially the epidermis), while most WT cells ...
Regulation of plasminogen activator inhibitor 1 expression in human
Regulation of plasminogen activator inhibitor 1 expression in human

... posed of small numbers of chondrocytes and large amounts of extracellular matrix (ECM). The ECM synthesized by chondrocytes has a high water content and contains collagen, proteoglycan (PG), metalloproteinases, and other small molecules; it plays an essential role in cartilage structure and function ...
Stacks off tracks
Stacks off tracks

... confocal laser scanning system (Sparkes et al., 2009b), and 2) a custom-built TIRF- ...
Evidence that FGF8 signalling from the midbrain
Evidence that FGF8 signalling from the midbrain

... (Danielian and McMahon, 1996), here designated pWEXPZ2. Each contains a Wnt-1 minigene upstream of the 5.5 kb 3-prime located Wnt-1 enhancer sequences. In pWEXPZ2 an approximately 800 base pair region in the Wnt-1 3-prime UTR has been deleted. This has no effect on the previously reported expression ...
Vesicles versus Tubes: is ER-Golgi Transport in
Vesicles versus Tubes: is ER-Golgi Transport in

... been identified also in bright structures of unknown identity (Faso et al., 2009). It has ...
Section 1 Sponges
Section 1 Sponges

... some other object. A fringe of tentacles surrounds the mouth, located at the free end of the body. Many cnidarians exist only as medusas, while others exist only as polyps. Still others alternate between these two phases during the course of their life cycle. The cnidarian body has two layers of cel ...
MRI Tissue Perfusion Quantification
MRI Tissue Perfusion Quantification

... Nuclear Magnetism Principles . . . . . . . . . . . . . . 22 ...
Inhibitory Regulation of Higher-Plant Myosin by
Inhibitory Regulation of Higher-Plant Myosin by

... was not reversible upon Ca21 removal. An 18-kD polypeptide that showed the same mobility in sodium dodecyl sulfate-polyacrylamide gel electrophoresis as that of spinach calmodulin (CaM) was present in this myosin fraction. This polypeptide showed a mobility shift in sodium dodecyl sulfate-polyacryla ...
Evidence for an apical Na–Cl cotransporter involved in ion uptake in
Evidence for an apical Na–Cl cotransporter involved in ion uptake in

... consistent with the current accepted model for ion secretion by MRCs in seawater. In this study, we unexpectedly encountered another type of MRC, exclusively found in freshwater-acclimatized embryos, which showed basolateral Na+/K+-ATPase and apical (and no basolateral) NKCC immunoreactivity. Althou ...
Physiological basis for high CO2 tolerance in
Physiological basis for high CO2 tolerance in

... phosphate groups. As buffering can only mask protons during an acidotic pH shift and thus reduce pH changes compared to a non-buffered system, surplus protons have to be eliminated to restore the original fluid pH. This can only be achieved by means of active ion transport across specialized epithel ...
Biogeosciences
Biogeosciences

... phosphate groups. As buffering can only mask protons during an acidotic pH shift and thus reduce pH changes compared to a non-buffered system, surplus protons have to be eliminated to restore the original fluid pH. This can only be achieved by means of active ion transport across specialized epithel ...
The SOX9 upstream region prone to chromosomal aberrations
The SOX9 upstream region prone to chromosomal aberrations

... Identification of ten putative enhancers in the –350-kb region upstream of Sox9 In order to identify enhancers that may directly control SOX9 expression in the chondrocyte lineage and whose disruption may contribute to causing campomelic dysplasia, we examined the mouse ortholog of the human SOX9 –3 ...
Physiological basis for high CO2 tolerance in marine
Physiological basis for high CO2 tolerance in marine

... phosphate groups. As buffering can only mask protons during an acidotic pH shift and thus reduce pH changes compared to a non-buffered system, surplus protons have to be eliminated to restore the original fluid pH. This can only be achieved by means of active ion transport across specialized epithel ...
(apoE) Transgenic Mice
(apoE) Transgenic Mice

... sections were incubated in biotinylated secondary antibodies, and detection of the peroxidase reaction product with diaminobenzidine (DAB) was performed with the ABC Elite kit (Vector Laboratories, Burlingame, CA) as described previously (Holtzman et al., 1995a). For doublelabeling immunofluorescenc ...
Upfront For Consumers The AAC-RERC Clinical News Equipment
Upfront For Consumers The AAC-RERC Clinical News Equipment

... for Coverage of AAC Devices, the Medicare working group demonstrated that SLPs routinely recommend AAC devices as a component of treatment for individuals with dysarthria, apraxia of speech and/or aphasia so severe they are unable to meet their communication needs through natural modes of communicat ...
Coactivation of Syk Kinase and MyD88 Adaptor Protein Pathways by
Coactivation of Syk Kinase and MyD88 Adaptor Protein Pathways by

... neutrophils to produce substantial amounts of IL-10 and CXCL2 (Figure 4C and Figures S8A and S9B). LPS, but not TLR7 or TLR9 agonists, also synergized with curdlan to induce IL-10 production by neutrophils (data not shown). The NOD2 agonist MDP combined with curdlan had no effect on IL-10 production ...
Utilization and Transport of Mannitol in Olea
Utilization and Transport of Mannitol in Olea

... grown in a medium with 1% (w/v) mannitol, and the uptake of D-[14C]mannitol was measured in cell aliquots harvested from the culture at the times indicated in Fig. 5. When the external levels of mannitol fell below 0.05% (w/v) (day 13), the activity of the polyol transport system increased abruptly ...
ภาพนิ่ง 1
ภาพนิ่ง 1

... vp) that are blocked at other steps in the carotenoid pathway also have reduced levels of ABA and exhibit vivipary. ...
Two different but converging messenger pathways to intracellular
Two different but converging messenger pathways to intracellular

... In general, the actions of most hormones and neurotransmitters, which release Ca2+ from internal stores, are blocked by heparin used as an IP3 receptor antagonist, but the possible involvement of cADPR and NAADP receptors has not been tested (Petersen and Cancela, 1999). It is therefore not known wh ...
Interactions of Elongation Factor 1 Cell Protrusions with F-Actin and
Interactions of Elongation Factor 1 Cell Protrusions with F-Actin and

... sorting of ␤-actin protein to this region. ␤-Actin has been suggested to be an important player in leading edge dynamics by virtue of its isoform-specific interaction with other proteins (such as ezrin and ␤-Cap73; Shuster et al., 1996). The sorting of ␤-actin mRNA requires transport and then select ...
Australian regulatory guidelines for medical devices
Australian regulatory guidelines for medical devices

... medical devices in Australia. The ARGMD also describes post-market requirements for medical devices. Regulatory guidance on other therapeutic devices that are listed or registered is not included. The Australian Medical Device Requirements Under the Therapeutic Goods Act 1989 (version 4), or DR4, av ...
Cytolysin-dependent delay of vacuole maturation in
Cytolysin-dependent delay of vacuole maturation in

... with lysosomes (Alvarez-Dominguez et al., 1997; AlvarezDominguez and Stahl, 1999). Alternatively, there is evidence that activation of Rab5a on Lm vacuoles decreases bacterial escape (Prada-Delgado et al., 2005). In addition to its role in perforating membranes for Lm escape into cytosol, LLO could ...
The Role Of The Planar Cell Polarity Pathway In The Second Heart
The Role Of The Planar Cell Polarity Pathway In The Second Heart

... Outflow Tract (OFT) malformations underlie a majority of congenital heart defects (CHD) in humans and are a leading cause of childhood mortality. The OFT, which gives rise to the aorta and pulmonary artery of the heart, relies on the contribution of the Second Heart Field (SHF) progenitors in the ph ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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