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Endocytosis Via Caveolae
Endocytosis Via Caveolae

... 50, 57–67). The entry process of this non-enveloped DNA virus, analyzed in several laboratories including ours, is emerging as a useful paradigm in the field. SV40 has several advantages as a model ligand. The particle itself is well characterized in terms of composition and structure. The X-ray str ...
70 Histopathology The mouse liver is made up of a large number of
70 Histopathology The mouse liver is made up of a large number of

... up of thousands of lobules which contain hepatic cells that are the basic metabolic cells of the liver. The liver has to perform certain important functions that include the break down of fats, production of urea, conversion of glucose derived from the food into glycogen, preparation of vital amino ...
Tubulin folding is altered by mutations in a putative GTP binding motif
Tubulin folding is altered by mutations in a putative GTP binding motif

... Davis et al. (1994) have shown that this region encompassing amino acids 103-109, a highly conserved region of β-tubulins, participates in GTP-binding and hydrolysis. A critical feature of the phosphate binding sequence in non-tubulin NTP-binding proteins is that it is contained in a glycine-rich lo ...
The cell biology of bone metabolism
The cell biology of bone metabolism

... histological types of mature bone: cortical or compact bone which has a dense, ordered structure and cancellous or trabecular bone which is lighter, less compact and has an irregular structure. Cortical or compact bone is found mainly in the shaft of long bones and the surfaces of flat bones. It is ...
Cooperative organization of bacterial colonies: from genotype to
Cooperative organization of bacterial colonies: from genotype to

... 49, 54) the above observations can be understood as follows: The cellular reproduction rate, that determines the growth rate of the colony, is limited by the level of nutrients available for the cells. The latter is limited by the diffusion of nutrients towards the colony (for low nutrient substrate ...
Hormonal regulation of stem cell maintenance in roots
Hormonal regulation of stem cell maintenance in roots

... such that through a Methylation-Sensitive Amplification Polymorphism technique and an immunocytological approach, plant growth and tightly controlled space and time. No single hormone bymethyltransferase, itself in regulating respectively. The development expression ofare one member of the in CHROMO ...
Molecular Plant-Microbe Interactions
Molecular Plant-Microbe Interactions

... acridine orange as the mutagen. PgyBR1Rif-O1 showed a significant growth reduction (approximately 10-fold) in soybean compared with that of the wild-type strain (Fig. 1A). However, the reduction in bacterial multiplication could not be restored in PgyBR1Rif-O1 expressing HopZ1b carried on pUCP20tk ( ...
GATA-2 functions downstream of BMPs and CaM KIV in ectodermal
GATA-2 functions downstream of BMPs and CaM KIV in ectodermal

... activity. In contrast, the N-terminus of 1-Smads has a weak sequence homology to the MH1 domain of R-Smads and does not bind to DNA (Shi and Massague, 2003). Smads bind to a consensus motif called the Smad-binding element (SBE) on target DNA, which has the sequence GCTC. Smad targets contain one or ...
A Critical Role for Egr-1 Characterization of CD44 Induction by IL-1:
A Critical Role for Egr-1 Characterization of CD44 Induction by IL-1:

... dNTP, 1.5 mM MgCl2, 200 pmol of each primer, and 1.75 U Taq polymerase. The reaction mixture was brought to a temperature of 95°C for 5 min, followed by amplification for 30 cycles, 0.5-min denaturation at 95°C, 1-min annealing at 55°C, 1-min extension at 72°C, followed by final extension at 72°C fo ...
BIO_105_S_2013_Final_Exam_QA130531.5c
BIO_105_S_2013_Final_Exam_QA130531.5c

... 85. Which of the following is not a structure found in the urinary system? A) ureters B) kidney C) pancreas D) urethra 86. The removal of metabolic wastes from the body is called __________ A) secretion B) defecation C) excretion D) maintenance 87. Besides the excretion of metabolic wastes, which of ...
FGF-dependent midline-derived progenitor cells in hypothalamic
FGF-dependent midline-derived progenitor cells in hypothalamic

... Mouse mutants that lack LHX2 expression show unusually high levels of proliferation in the ventral diencephalic floor, with concomitant failure of infundibular evagination (Zhao et al., 2010). In Fgf10 knockout mice, furthermore, the infundibulum similarly fails to evaginate fully and infundibular c ...
O B  RGANIC
O B RGANIC

... Since the Nobel Prize awarded discovery that some polymers or “plastics” can be made electronically conducting, the scientific field of organic electronics has arisen. The use of conducting polymers in electronic devices is appealing, because the materials can be processed from a liquid phase or fro ...
PDF How your lungs work British Lung Foundation
PDF How your lungs work British Lung Foundation

... Lungs and How They Fuel Our Bodies With Oxygen The Respiratory System. Figure A shows the location of the respiratory structures in the body. Figure B is an enlarged  How Your Lungs Work HowStuffWorks They can become very short of breath and cells of the body, and the body systems dont work as well ...
RECQ5 helicase promotes resolution of conflicts between
RECQ5 helicase promotes resolution of conflicts between

... after NC block release, whereas the late-replicating rDNA was detected 12–16  h after release (Fig.  3  A). Hence, mock- and RECQ5-depleted cells were cross-linked at 8 or 14  h after NC block release and subjected to ChIP assay using antibody against the catalytic subunit of Pol ε.  We found that R ...
Heat shock results in cell cycle delay and synchronisation of mitotic
Heat shock results in cell cycle delay and synchronisation of mitotic

... which morphogenesis appears relatively normal, and the other in which gastrulation movements are virtually halted, or in which the order of events is grossly perturbed. Upon recovery, the former category displayed reasonably normal patterns of division with a slight perturbance in the sequence in wh ...
Neural Activity in Primary Motor Cortex Related to Mechanical Loads
Neural Activity in Primary Motor Cortex Related to Mechanical Loads

... surgically under inhalation anesthetic. Neurons recorded in the task were located in the rostral bank and crown of the central sulcus where trains of electrical stimulation (11 pulses, 333 Hz, 0.2-ms pulse width, range 5–50 ␮A) elicited movement of the shoulder or elbow. The territory where cell act ...
Physics - BC Open Textbooks
Physics - BC Open Textbooks

... Calcium entry through postsynaptic NMDA receptors can initiate two different forms of synaptic plasticity: long-term potentiation (LTP) and long-term depression (LTD). LTP arises when a single synapse is repeatedly stimulated. This stimulation causes a calciumand CaMKII-dependent cellular cascade, w ...
CURRICULUM VITAE
CURRICULUM VITAE

... development of viral vaccines under GMP standards at the Instituto Butantan, S.Paulo, Brasil. Vice-President of the Brazilian Society of Immunology (1995-1997). Associate Professor and consultant of the University of Strasbourg, “Ecole Europeènne de Biotechnologie de Strasbourg, France” (1995-2001) ...
*Owners manual for the human body* Dr Darko Valec
*Owners manual for the human body* Dr Darko Valec

... world of ours, who are we and how do we fit in relation to others. There will be some confusion at the very beginning. Who was correct, Newton or Einstein?  They were both correct by describing two different realities. One reality is about our physical laws in our three dimensional view of our Univ ...
Protists Cells: Grow and Develop:
Protists Cells: Grow and Develop:

... Protists and the animal and plant kingdoms, they still use these kingdoms to help describe the different types of Protists. Protists are animal like, plant like, or fungi like. Protists are so small that they do not need any special organelles to take in gas or get rid of waste. They rely on simple ...
Tulkens
Tulkens

... A certain serum AUC and a certain serum peak will determine the drug concentration at the target level which may prevent the selection of first and second mutation resistants ...
Respiration and Circulation
Respiration and Circulation

... The walls of alveoli are only one cell thick. The thin walls and the large surface areas of the alveoli enable a high rate of gas exchange. If you could spread out all the alveoli in your lungs onto a flat surface, they would cover an area bigger than most classrooms. Every time you breathe, your al ...
CHAPTER 19: RESPIRATORY SYSTEM
CHAPTER 19: RESPIRATORY SYSTEM

... At the end of an expiration, the alveoli tend to recoil inward and collapse on themselves; Surfactant (mixture of phospholipid & proteins) produced by Type II Alveolar cells decreases the surface tension in the lungs; As the alveoli become smaller during expiration, the surfactant overcomes the pres ...
Supporting Information
Supporting Information

... We detected the Dictyostelium GFP-Cln3 fusion protein as a ~50 kDa band on western blots. Although the expected molecular weight of Dictyostelium GFP-Cln3 was ~75 kDa (Cln3, 47 kDa, www.dictybase.org; GFP, 27 kDa), the relative hydrophobicity of the protein and evidence from other systems where simi ...
Evaluation of cell membrane integrity as a potential antimicrobial
Evaluation of cell membrane integrity as a potential antimicrobial

... Bacterial cell membranes can be used as a target for the development of new antibacterial drugs. Many plants produce secondary metabolites which contain a steroid or triterpernoid aglycon attached to one or more sugar chains that exhibit cell membrane permeabilizing properties [11]. Permeability enh ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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