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Characterization of Mg -regulated TRPM7
Characterization of Mg -regulated TRPM7

... conditions they pass very weak inward current due to substantial down-regulation by high levels of intracellular Mg2+ ...
Neuronal body size correlates with the number of nucleoli
Neuronal body size correlates with the number of nucleoli

... rates have demonstrated that differences in cell size correspond to differences in RNA content and a tight correlation has also been shown to exist between transcription rates and RNA:DNA ratios in cells from adult rodents (Schmidt and Schibler, 1995). Moreover, the effect of transcription on cellul ...
ch 9 cellular respiration - OG
ch 9 cellular respiration - OG

... Where do light-independent reactions take place in the chloroplast? 30 pts Photosynthesis II ...
Phosphoinositide signaling in plant development
Phosphoinositide signaling in plant development

... 2016). The transcription of some enzymes of PI metabolism is also induced upon perception of environmental stresses. For instance, in Arabidopsis transcription of the PLC1 gene is induced upon dehydration and salt stress (Hirayama et al., 1995) and that of PIP5K1 by exogenous auxin (Tejos et al., 20 ...
Manipulation of oxidative protein folding and PDI redox state in
Manipulation of oxidative protein folding and PDI redox state in

... serological detection, we tagged murine J chains with the myc epitope. To synchronize disul®de bond formation and to uncouple oxidation and isomerization, JcM expressing HeLa transfectants were pulsed in the presence of dithiothreitol (DTT) (Braakman et al., 1992a; Valetti and Sitia, 1994), and then ...
Translation without eIF2 Promoted by Poliovirus 2A Protease
Translation without eIF2 Promoted by Poliovirus 2A Protease

... inactivated by treating culture cells with Ars to induce phosphorylation of eIF2a. This compound induces oxidative stressand has been widely used to inactivate eIF2 [35,36,37]. A PV replicon (pRLuc31) containing the luciferase (luc) gene replacing the viral structural proteins was used [38]. As cont ...
Manipulation of oxidative protein folding and PDI redox state in
Manipulation of oxidative protein folding and PDI redox state in

... serological detection, we tagged murine J chains with the myc epitope. To synchronize disul®de bond formation and to uncouple oxidation and isomerization, JcM expressing HeLa transfectants were pulsed in the presence of dithiothreitol (DTT) (Braakman et al., 1992a; Valetti and Sitia, 1994), and then ...
phospholipid: as novel excipient
phospholipid: as novel excipient

... World Journal of Pharmacy and Pharmaceutical Sciences ...
Overview of problem fermentations
Overview of problem fermentations

... of cells supported by medium, absence of inhibitory ethanol • Stage 3: Transition: at this point ethanol has become inhibitory to continued maximal fermentation; cells are adjusting plasma membrane composition and internal membranes and proteins to an ethanol tolerant form • Stage 4: Maximal ferment ...
Station 1: Components of prokaryotic cells
Station 1: Components of prokaryotic cells

... Bacteria reproduce by binary fission. In this process the bacterium, which is a single cell, divides into two identical daughter cells. Binary fission begins when the DNA of the bacterium divides into two (replicates). The bacterial cell then elongates and splits into two daughter cells each with id ...
Intravenously-Delivered Mesenchymal Stem Cells: Systemic Anti
Intravenously-Delivered Mesenchymal Stem Cells: Systemic Anti

... transdifferentiate into functional myocardium, stimulate resident myocardial stem cells to expand and repopulate the heart with functioning myocytes, or secrete substances leading to myocardial repair15-17. This orientation, along with the demonstration that stem cells, administered intravenously, o ...
Group-specific effects on coastal bacterioplankton of
Group-specific effects on coastal bacterioplankton of

... with phytoplankton blooms. Altogether, these observations indicate that there are specific associations between species of Bacteria and phytoplankton. Since distinct bacterial groups appear to be differently affected by PUAs, the high local concentrations of these compounds in the surroundings of di ...
Identification and characterization of a cluster of transcription start
Identification and characterization of a cluster of transcription start

... also. In addition, three 59 ends were mapped to nt 430, 441 and 446. To verify the novel 59 ends, RNase protection studies were performed with total RNA extracted from CaSki cells. A long antisense probe spanning the region of nt 53–632 (probe F) of the HPV-16 genome was hybridized with different am ...
Leading to a Mild Immunodeficiency Activator trans
Leading to a Mild Immunodeficiency Activator trans

... The expression of MHC class II molecules is essential for all Ag-dependent immune functions and is regulated at the transcriptional level. Four trans-acting proteins control the coordinate expression of MHC class II molecules: class II trans-activator (CIITA), regulatory factor binding to the X box ...
AP Biology - Freehold Regional High School District
AP Biology - Freehold Regional High School District

... mechanisms. Science is a way of knowing. It can involve a discovery process using inductive reasoning, or it can be a process of hypothesis testing. ...
Noticing Familiar Objects in Real World Scenes: The Role of
Noticing Familiar Objects in Real World Scenes: The Role of

... Figure 1. Stimuli and conditions used in the experiment. A, Subset of target images. Monkeys were trained to pull one of two levers whenever they noticed any 1 of 70 target objects on the computer monitor set before them. Lever mappings (left or right) were arbitrarily assigned, but specific exempla ...
Standard PDF - Wiley Online Library
Standard PDF - Wiley Online Library

... the size and number of chloroplasts vary between these tissues (Table 1). Bizonoplasts, giant cup-shaped unique chloroplasts with dimorphic ultrastructural organization in a single chloroplast, are located in dorsal epidermal cells: the upper zone is occupied by numerous layers of two to four stacke ...
Apical constriction
Apical constriction

... mesenchymal transition (EMT) (Anstrom, 1992; Nance and Priess, 2002; Harrell and Goldstein, 2011; Williams et al., 2012). Apical constriction is also associated with the extrusion of apoptotic or delaminating cells (Toyama et al., 2008; Slattum et al., 2009; Marinari et al., 2012) and wound contract ...
Dissection of the Rat
Dissection of the Rat

... 6. The pancreas is not a clearly identifiable organ but a thin membrane that overlays the stomach and spleen. The pancreas produces digestive enzymes that are sent to the intestine via small ducts (the pancreatic duct). The pancreas also secretes insulin which is important in the regulation of gluco ...
Apical constriction: themes and variations on a cellular mechanism
Apical constriction: themes and variations on a cellular mechanism

... mesenchymal transition (EMT) (Anstrom, 1992; Nance and Priess, 2002; Harrell and Goldstein, 2011; Williams et al., 2012). Apical constriction is also associated with the extrusion of apoptotic or delaminating cells (Toyama et al., 2008; Slattum et al., 2009; Marinari et al., 2012) and wound contract ...
Digestion Index
Digestion Index

... The digestive tract extends from the lips to the anus. It includes the mouth, pharynx, esophagus, stomach, and the small and large intestines. Accessory glands include the salivary glands, the liver, and the pancreas. The length and complexity of the digestive system depends on the species. In herbi ...
intraoperative awakening for vision examination during ophthalmic
intraoperative awakening for vision examination during ophthalmic

as Adobe PDF - Edinburgh Research Explorer
as Adobe PDF - Edinburgh Research Explorer

... Mouse mutants that lack LHX2 expression show unusually high levels of proliferation in the ventral diencephalic floor, with concomitant failure of infundibular evagination (Zhao et al., 2010). In Fgf10 knockout mice, furthermore, the infundibulum similarly fails to evaginate fully and infundibular c ...
Cell cycle regulation by the bacterial nucleoid
Cell cycle regulation by the bacterial nucleoid

... the cell is ready to divide. In Bacteria this normally occurs by binary fission and in almost all species this is initiated by the assembly of the tubulin homologue FtsZ into a ring-like structure (‘Z-ring’) at the nascent division site (Figure 1) [1]. The Z-ring then functions as a dynamic platform ...
Endocytosis Via Caveolae
Endocytosis Via Caveolae

... 50, 57–67). The entry process of this non-enveloped DNA virus, analyzed in several laboratories including ours, is emerging as a useful paradigm in the field. SV40 has several advantages as a model ligand. The particle itself is well characterized in terms of composition and structure. The X-ray str ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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