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Physical and Chemical Basis of Cytoplasmic Streaming
Physical and Chemical Basis of Cytoplasmic Streaming

... There are a numberof reviews and symposia reports dealing with various aspects ofnonmuscularcell motility including cytoplasmic streaming (8, 10, 11, 23, 28, 31, 36, 48, 53, 59, 60, 62, 99, 100, 134, 136, 139, 15o, 151, 159). They will provide readers with more comprehensive information on the subje ...
Infection of Mesothelial Cells with Human Herpes Virus 8 in
Infection of Mesothelial Cells with Human Herpes Virus 8 in

... expressing either latent nuclear antigens or the viral homolog of human interleukin-6 (vIL-6), respectively (10, 11, 13–15). In primary effusion lymphoma, the malignant cells have been shown to be infected with HHV 8 in both the latent and lytic phases (16 –18). Circulating B cells, T cells, and mon ...
Nucleoredoxin and Wnt signaling in F9 cells
Nucleoredoxin and Wnt signaling in F9 cells

... Wnt/β-catenin pathway through binding dishevelled. When Wnt is present, dishevelled prevents a destruction complex from degrading β-catenin. This facilitates the translocation of β-catenin into the nucleus where it binds to TCF-LEF to impart changes in gene expression. This study used mouse F9 cells ...
Supplementary information
Supplementary information

... A. ATP dependence of Hsp90β and Hsp70-Hdj1 were compared by the incubation of indicated molecular chaperones with WT p53 (protein concentrations as in main text, Fig. 3), in the presence of 0, 5 and 7 mM of ATP, at temperatures and time periods that allow to distinguish specific activities of both c ...
Multiple post-translational modifications regulate E
Multiple post-translational modifications regulate E

... exacerbating apoptosis. The modifications of E-cadherin by O-GlcNAcylation and lack of pro-region processing represent novel mechanisms for rapid regulation of cell surface transport of E-cadherin in response to intoxication. Key words: E-cadherin, Modifications, O-linked b-N-acetylglucosamine, Tran ...
Chapter 2: Nerve Cells and Nerve Impulses
Chapter 2: Nerve Cells and Nerve Impulses

... 51. The main feature that distinguishes a neuron from other animal cells is that a neuron has: A. a larger nucleus. B. a distinctive shape. C. the ability to metabolize a variety of fuels. D. a high internal concentration of sodium ions. 52. One of the most distinctive features of neurons compared ...
Chalcogenide glass microphotonics: Stepping into the spotlight
Chalcogenide glass microphotonics: Stepping into the spotlight

... ratios of the resonator after multiple bending cycles at a bending radius of 0.5 mm.11 manufacturing side, flexible photonics identify the molecule type, whereas photonic devices, we chose CaF2, an IR integrate seamlessly into large-area roll-tooptical absorption strength quantifies crystal with a l ...
The `ins` and `outs` of flavonoid transport
The `ins` and `outs` of flavonoid transport

... flower color [1]. Flavonoids have been associated with many favorable agronomic traits and health benefits to humans, and their metabolic engineering is therefore an important target for plant biotechnology [2,3]. Pathways, enzymes and regulatory mechanisms of flavonoid biosynthesis have been well s ...
STUDENT - BODY WORLDS Vital
STUDENT - BODY WORLDS Vital

... BODY WORLDS: Pulse shows the science and splendour of the human body, and deconstructs its form and function. It presents the body in health and distress, its vulnerabilities and potential, and many of the challenges the human body faces as it navigates the 21st Century. “Pulse” is a convergence of ...
Expression of the Nucleus-Encoded Chloroplast Division Genes and
Expression of the Nucleus-Encoded Chloroplast Division Genes and

... division-related genes and proteins that are encoded in some of these algal chloroplast genomes were analyzed. The results show that most but not all the nucleus-encoded chloroplast division genes and proteins, regardless of origin, are expressed during the S phase and that the expression of the chl ...
UPC
UPC

... Hazen KC, Lemelle WG. Improved assay for surface hydrophobia avidity of Candida albicans cells. Appl Environ Microbiol 1990; 56: 1974-1976. Hermansson M, Kjelleberg S, Korhonen TK, Stenstrom TA. Hydrophobie and electrostatic characterization of surface structures of bacteria and its relationship to ...
Chapter 4
Chapter 4

...  Thick membrane composed of several layers of cells  Function in protection of underlying areas subjected to abrasion  Forms the external part of the skin’s epidermis (keratinized cells), and linings of the esophagus, mouth, and vagina (nonkeratinized cells) ...
machinery pre-mRNA in sensing defects in the spliceosomal Mdm4
machinery pre-mRNA in sensing defects in the spliceosomal Mdm4

... (ER) mice, which allowed the triggering of a recombination event in both live animals and, ex vivo, primary cells by using 4-hydroxytamoxifen (OHT). We switched to the Prmt5F/FER system for three main reasons: First, it allowed us to look at cell-autonomous defects. Second, we could derive a much la ...


... economics. In 2009, there was a reported 33.3 million people living with HIV and 2.6 million new infections that same year [32]. HIV is characterized by a persisting infection that targets and significantly depletes CD4 T cells, which are important helpers for generation of an optimal CTL response. ...
c-Myc Overexpression Increases Cell Size and Impairs Cartilage
c-Myc Overexpression Increases Cell Size and Impairs Cartilage

... Overexpression of c-myc Resulted in Limb Buds of Larger Size than Normal. To obtain forced expression of c-myc, we used a retroviral vector (RCASBP-A) containing the c-myc coding region (26). Concentrated viral stocks were injected into the prospective right-wing field of stage 12–14 embryos or dire ...
Nucleolar localization of an isoform of the IGF
Nucleolar localization of an isoform of the IGF

... the mature IGF-I peptide. IGF-I exon 1 encodes part of a signal peptide from residues MGK [-48 to -46] to K [-28]. Exon 3 encodes the remainder of the signal peptide from residues VKM [-27 to -25] to A [-1]. This was cloned upstream of the cDNA for GFP. Exon 3 encodes the mature IGF-I peptide starti ...
SETD6 is a negative regulator of oxidative stress response
SETD6 is a negative regulator of oxidative stress response

... other diseases remains mostly unknown. In order to deepen our knowledge of SETD6, we used IP/MS to identify proteins that interact with endogenous SETD6 in K562 cells (Fig. 1A). Approximately 115 SETD6 bound proteins were identified (Supplementary Table T1), including DJ1, a sensor for oxidative stre ...
Cellular Biology - Circulation Research
Cellular Biology - Circulation Research

... Rationale: Polyploidy and multinucleation are characteristic features of mammalian cardiomyocytes, which develop shortly after birth when most differentiated cardiomyocytes become acytokinetic. Cardiac overload and hypertrophy further increase the degree of polyploidy of cardiomyocytes, suggesting a ...
THERAPEUTICS III
THERAPEUTICS III

... structures that carry the air from the larynx to the alveoli of the lungs. Looking at a person UPSIDE DOWN, the trachea is the trunk of the tree and the bronchi are the branches. These tubular parts are held open (made patent) by rings of cartilage. Their lining is ciliated to remove mucus and other ...
New immunotherapies targeting the
New immunotherapies targeting the

... viral infection in several animal models and is the basis for future clinical trials manipulating PD-1 signaling in infectious disease. Mechanisms controlling PD-1 expression Considering the clinical importance of these molecules, there is great interest in understanding the mechanisms behind their ...
Urine Reflection of Changes in Blood
Urine Reflection of Changes in Blood

Chemical Microscopy Applied to Biological Systems
Chemical Microscopy Applied to Biological Systems

... determine the spatial distribution of fluorescent probes, which usually describe a given molecular property, subcellular compartment, or function of a biological sample. An overview of the principles, instrumentation, and factors that affect the quality of fluorescence microscopy images was publishe ...
ARE ECOSYSTEMS ALIVE? - Journals ISSS
ARE ECOSYSTEMS ALIVE? - Journals ISSS

... birds, or the cytosol and the items within it—groups of units. The amoeba is a compound system in that its components have both coherent and noncoherent relations, with the latter contained by the former. A coherently contained compound system, as a whole, exists in the form of an individual unit—a ...
chapter 8 -- the nervous system
chapter 8 -- the nervous system

... Relationship between structure and function: Structure—function relationships are easy to demonstrate in red blood cells and in the hemoglobin molecule. The shape of the RBC, a biconcave disc, increases surface area, and allows the cell to fold as it passes through the smallest capillaries. Without ...
implementation of medicinal leech preparation to investigate the
implementation of medicinal leech preparation to investigate the

... potentials at the resting and active states of the cell. The Nernst equation describes the voltage across the membrane when each ion that crosses the membrane in one direction due to diffusion is exactly balanced by an ion that crosses the cell membrane in the other direction due to drift with the e ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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