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Enzymatic inactivation of endogenous IgG by IdeS enhances
Enzymatic inactivation of endogenous IgG by IdeS enhances

The Grapevine fleshless berry Mutation. A Unique
The Grapevine fleshless berry Mutation. A Unique

... Commonwealth Scientific and Industrial Research Organization Plant Industry, and the Institut National de la Recherche Agronomique departments of Caractérisation et Elaboration des Produits Issus de l’Agriculture and Génétique et Amélioration des Plantes. ...
Diacylglycerol kinases - University of Toronto Mississauga
Diacylglycerol kinases - University of Toronto Mississauga

... All DGKs have at least two cysteine-rich regions homologous to the C1A and C1B motifs of PKCs [26]. In theory, these domains may bind DAG, perhaps localizing DGKs to where DAG accumulates. However, no DGK C1 domain has so far been conclusively shown to bind DAG. In fact, structural predictions sugge ...
An Ancient Yeast for Young Geneticists: A Primer on the
An Ancient Yeast for Young Geneticists: A Primer on the

... genes involved in fundamental mechanisms of transcription, translation, DNA replication, cell cycle control, and signal transduction, to name but a few processes. However, since the divergence of the two species approximately 350 million years ago, S. pombe appears to have evolved less rapidly than ...
Electrospun aniline-tetramer-co-polycaprolactone fibers for
Electrospun aniline-tetramer-co-polycaprolactone fibers for

... [Fig. 1(a)]. However, the instability of HCl doping led to immediate de-doping when immersed in physiological buffer (PBS). This prevents its use as dopant for cell culture membranes, where stable doping is required. Phytic acid has been reported as a stable dopant for poly(aniline),[28] and we ther ...
Signaling tip growth in plants Zhenbiao Yang
Signaling tip growth in plants Zhenbiao Yang

... tubes into bulbous tubes (H Li and Z Yang, unpublished data). These results indicate that Rop controls not only the establishment of cell polarity but also tip growth, as does CDC42 in tip-growing fission yeast [8]. The bulbous phenotype is analogous to tip swelling accompanied by non-localized intr ...
The physical basis of active mechanosensitivity by the hair
The physical basis of active mechanosensitivity by the hair

... tension has been estimated at approximately 8 pN along the oblique axis of each tip link at a resting open ...
Poster
Poster

... Researchers study prions in yeast rather than mammalian prions because of: ● Similar behavior ● Nominal risk ● Yeast have short life cycle ● Yeast are easy to cultivate ...
Functional ultrastructure of the plant nucleolus
Functional ultrastructure of the plant nucleolus

... rRNA synthesis rate as well as for efficient pre-rRNA processing (Schneider et al. 2007). The issue of RNA polymerase I action and main factors participating in this process was the focus of the recent review (Schneider 2012). Concerning plants, little is known about transcription factors constituti ...
Apoptin protein multimers form distinct higher
Apoptin protein multimers form distinct higher

... Received April 30, 2003; Revised May 28, 2003; Accepted June 5, 2003 ...
Immunohistochemical sweat gland profiles
Immunohistochemical sweat gland profiles

... stronger than that of CK 8 and CK 14.22 A controversy exists about the presence of CK 10.22,34 The present findings using the CAM 5.2 antibody are in line with the current concepts. A positivity was found in both the ESG and ASG, and in the presumed apoeccrine glands. By contrast, the S100-B immunor ...
4T, 3T AND 3T1D DRAM CELL DESIGN ON 32 NM
4T, 3T AND 3T1D DRAM CELL DESIGN ON 32 NM

... memory cell, all the possible variations can be lumped into a timing degradation. In this sense 3T1D tolerates higher levels of variability than 6T cell, which incurs into timing degradation as well as instability. [1] Manufacturing process introduces variations in devices characteristic parameters, ...
6.3. La supervivencia de las motoneuronas espinales de pollo mantenidas
6.3. La supervivencia de las motoneuronas espinales de pollo mantenidas

... mediated MTN survival and the intracellular pathways involved in this process, we have investigated the ability of GDN F, NTN, and PSP to activate PI 3-kinase and ERK–M AP kinase pathways. We provide evidence showing that all these neurotrophic factors are able to activate both pathways in our cultu ...
Neurotrophins: the biological paradox of survival factors
Neurotrophins: the biological paradox of survival factors

... Similarly, in vitro exogenous application of NGF to terminally differentiated primary rat cortical cultures of oligodendrocytes (Casaccia-Bonnefil et al, 1996b) or immortalized smooth muscle cells expressing p75 (Kraemer and Hempstead, personal communication), results in apoptotic death that could b ...
pET System Manual
pET System Manual

... recombinant proteins in E. coli. Target genes are cloned in pET plasmids under control of strong bacteriophage T7 transcription and (optionally) translation signals; expression is induced by providing a source of T7 RNA polymerase in the host cell. T7 RNA polymerase is so selective and active that a ...
In HIV-1/HBV Co-Infection Model, CPI-431
In HIV-1/HBV Co-Infection Model, CPI-431

... HCV/HBV-related liver disease is the main cause of morbidity and mortality of HIV-1 patients co-infected with HCV and/or HBV. Despite the recent advent of anti-HCV DAAs, the treatment of HCV/HBV/HIV-1 coinfected patients remains a challenge, as these patients are less responsive to treatment, have h ...
Bartonella Clarridgeiae: Invasion of Human
Bartonella Clarridgeiae: Invasion of Human

... confer protection against the other. B. clarridgeiae has been isolated from dogs with infective vegetative valvular endocarditis and in liver specimens from dogs with hepatic disease (Chomel et al.,2001; Gillespie et al.,2003). The number of human infections by B. clarridgeiae is unknown. It has be ...
Hydrostatic pressure-induced changes in cellular protein synthesis
Hydrostatic pressure-induced changes in cellular protein synthesis

... frequencies stimulate the synthesis, while overloading has an inhibitory effect [2–4,9,39,40]. Mechanical compression and hydrostatic loading had similar frequency-dependent stimulation of proteoglycan synthesis in tissue explants, while monolayer cultures required longer loading period to be stimul ...
Drug resistance patterns and susceptibility to
Drug resistance patterns and susceptibility to

... Lijinsky W 1968 Aflatoxins and nitrosamines: cellularIP: ...
Regulatory Roles for Long ncRNA and mRNA
Regulatory Roles for Long ncRNA and mRNA

... RNA. Only, their lack of protein coding ability and conservation is differentiating lncRNAs from mRNAs [26,32]. These are therefore the main criteria from telling both types of transcripts apart. Protein-coding ability—Proof of protein-coding ability can be obtained from experiments such as Western ...
Promiscuous and specific bacterial symbiont acquisition in the
Promiscuous and specific bacterial symbiont acquisition in the

... We isolated 17 strains of the amoeboid genus Nuclearia (Opisthokonta) from five Swiss lakes. Eight of these nucleariid isolates were associated with bacterial endosymbionts and/or ectosymbionts. Amoebae were characterized morphologically and by their 18S rRNA genes. Phylogeny based on molecular data ...
Nutrients and growth factors in mTORC1 activation
Nutrients and growth factors in mTORC1 activation

... almost certainly prove relevant for human diseases as cancer, neurodegeneration, diabetes and aging. Additional mouse models of deregulated nutrient sensing will certainly teach us additional aspects of physiology that are critically regulated by this pathway, which may be similar to or different fr ...
The Cytoskeleton as a Regulator and Target of
The Cytoskeleton as a Regulator and Target of

... A, Interaction between a plant and a filamentous pathogen, such as that between Arabidopsis and P. parasitica. Top, Microtubules (blue), actin microfilaments (red), and nuclei (green) before appressorium formation or attempted penetration. Bottom, Actin microfilaments become focused on the penetrati ...
A preliminary pharmacognostical study on leaves and flowers of
A preliminary pharmacognostical study on leaves and flowers of

... oils contained six sesquiterpene hydrocarbons, four oxygenated sesquiterpene, and two aliphatic alcohols from water using dichloromethane solvent in leaves of M.champaca L. There appears to be no Pharmacognostical work of this valued (leaves and flowers) traditional medicinal plant. In the present s ...
Golgi-SNARE GS28 potentiates cisplatin
Golgi-SNARE GS28 potentiates cisplatin

... samples as well as the controls were run in triplicate on the same plate. Relative quantification was calculated by the CT method and normalized to GAPDH. Namely, the CT for each candidate was calculated with the following equation: CT (candidate) = [CT (candidate) − CT (GAPDH)]. The relative ab ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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