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the nervous system
the nervous system

... of the following on the frequency of action potentials in the postsynaptic neuron. - spatial and temporal summation of post synaptic potentials - balance between active inhibitory and active excitatory synapses. ...
What drives the plasticity of brain tissues?
What drives the plasticity of brain tissues?

... physical activity, but neuronal activity} and learning are both involved in the behavioral events that appear to drive these processes, leads to the next natural question: what causes changes in neurons, glia and vasculature: Can we rule out artifactual causes such as hormonal or metabolic responses ...
MS Word Version - Interactive Physiology
MS Word Version - Interactive Physiology

... 24. (Page 9.) These are called _________ receptors, and norepinephrine acts indirectly when binding to them. a. adrenergic b. cholinergic 25. (Page 9.) Both alpha and beta adrenergic receptors are found in the central nervous system, and more importantly, on effector organs of the _____________ ____ ...
MS Word Version
MS Word Version

... 24. (Page 9.) These are called _________ receptors, and norepinephrine acts indirectly when binding to them. a. adrenergic b. cholinergic 25. (Page 9.) Both alpha and beta adrenergic receptors are found in the central nervous system, and more importantly, on effector organs of the _____________ ____ ...
Neurophysiology,Dr Sravanti
Neurophysiology,Dr Sravanti

...  EPSP – when the change causes depolarization, this is called an excitatory post synaptic potential. ...
Autonomic Nervous System ANS - Anderson School District One
Autonomic Nervous System ANS - Anderson School District One

... • α1 & β1 produce excitation when activated • α2 & β2 receptors cause inhibition of effector tissues • β3 found only on cells of brown adipose where activation causes thermogenesis (heat production) ...
Morphological Basis of Learning and Memory: Vertebrates
Morphological Basis of Learning and Memory: Vertebrates

...

Several structural features of synapses have been found to be altered by behavioral experience. One of the most obvious features is the size of synapses. Larger synapses may release more neurotransmitter or have more receptors, such that a size change could indicate a strength change. Early findi ...

Morphological Basis of Learning and Memory: Vertebrates
Morphological Basis of Learning and Memory: Vertebrates

... the synaptic input (see Figure 1), so the implication was that new synapses formed. Similar findings were subsequently reported in other areas of the cerebral cortex and in brain regions such as hippocampus, superior colliculus, and cerebellum. Of particular importance to learning and memory was tha ...
Target-cell-specific concentration of a metabotropic glutamate
Target-cell-specific concentration of a metabotropic glutamate

... have at least a ten· fold higher level of presynaptic mGluR7 than terminals making synapses with pyramidal cells and other types of interneuron. Distinct levels of mGluR7 are fo und at different synapses made by individual pyramidal axons or even single boutons. These results raise the possibility t ...
E4 - Neurotransmitters and Synapses - IBDPBiology-Dnl
E4 - Neurotransmitters and Synapses - IBDPBiology-Dnl

... Pre-synaptic membrane, making dopamine to remain active in the synapse  dopamine is associated with a feeling of pleasure , thus cocaine creates a mood of euphoria ...
NEUROTRANSMITTERS AND RECEPTORS
NEUROTRANSMITTERS AND RECEPTORS

... via gap junctions, chemical synapses involving neurotransmitters ...
Stages in Neuromuscular Synapse Elimination
Stages in Neuromuscular Synapse Elimination

... release Mg block of NMDA receptor, allowing Ca influx. NMDA receptor acts as a coincidence detector of the activity of neurons from a single source. They support one aspect of the theory of learning proposed by Hebb. An additional retrograde signal to the presynaptic neuron is required. ...
Unimodal or Bimodal Distribution of Synaptic Weights?
Unimodal or Bimodal Distribution of Synaptic Weights?

... Most Hebbian learning rules or BCM rules used to describe receptive field development exhibit a spontaneous separation of synaptic weights into two groups, i.e., strong and weak synapses, so that the distribution of synaptic weights is bimodal. This implies that even rather ‘weak’, non-significant c ...
breathing systems
breathing systems

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BGandcerebellum - UCSD Cognitive Science
BGandcerebellum - UCSD Cognitive Science

... i. Afferents for PC are Parallel fibers and Climbing Fibers 2. Purkinje Cell Layer (1 cell thick) a. Purkinje Cells: single type of efferent neuron in cerebellar cortex, inhibitor, project to cerebellar nucleus and vestibular nucleus b. Special computational features i. Calcium P currents underlying ...
Chapter 4
Chapter 4

... Neural impulse -The propagation of an action potential along an axon. The axon depolarizes in a sequential fashion from the axon hillock to the presynaptic terminal. The neural impulse occurs only one way because of the absolute refractory period. Speed of transmission varies due to thickness of the ...
excitatory neurotransmitter
excitatory neurotransmitter

... There are many neurotransmitters within the body and each type has its own distinct shape. The receptor sites that absorb the neurotransmitters are designed to only receive a specified neurotransmitter. Therefore the receptor sites have a matching shape to the neurotransmitter. The neurotransmitter ...
Document
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... exciting the neuron to fire more action potentials causing an increase in dopamine release. •Nicotine also affects neurons by increasing the number of synaptic vesicles released. ...
Nonneurolnal cells engineered to express neuroligins
Nonneurolnal cells engineered to express neuroligins

... scaffolding and signaling molecules, possibly via the PDZ-binding motif at the C-terminus. This scaffold may then signal the assembly of the exocytotic machinery and recruit additional neurexins and thereby neuroligins to form an expanding contact zone. Postsynaptic neuroligin-1 oligomers may contri ...
Chapter 48: Neurons, Synapses, and Signaling Reading Guide 48.1
Chapter 48: Neurons, Synapses, and Signaling Reading Guide 48.1

... 3. Which division of the nervous system includes the brain and spinal cord? 4. Draw two touching neurons in which a nerve impulse moves from the one on the left to the one on the right. (Use Figure 48.4 as a reference) Label the following elements: cell body, dendrites, axon, synapse, presynaptic ce ...
Chapter 48: Neurons, Synapses, and Signaling Reading Guide 48.1
Chapter 48: Neurons, Synapses, and Signaling Reading Guide 48.1

... 3. Which division of the nervous system includes the brain and spinal cord? 4. Draw two touching neurons in which a nerve impulse moves from the one on the left to the one on the right. (Use Figure 48.4 as a reference) Label the following elements: cell body, dendrites, axon, synapse, presynaptic ce ...
Synapses - UBC Zoology
Synapses - UBC Zoology

... • The resulting influx of Na+ produces a localized depolarization of the membrane • leading to opening of voltage-gated Na+ channels and generation of an action potential ...
2. Movement In and Out of Cells
2. Movement In and Out of Cells

... through the lungs and into the bloodstream. The oxygen is then transported throughout the body. Carbon dioxide is the waste gas produced by respiration. Carbon dioxide diffuses from body tissues into the bloodstream and is exhaled via the lungs. Where does gas exchange take place in the lungs? 12 of ...
Neurophysiology Neurotransmitter and Nervous System
Neurophysiology Neurotransmitter and Nervous System

... sites, but are not specific to an individual synapse. May be released far from the synapse. Act as a neuromodulator (modify the activity of a neurotransmitter) ...
Document
Document

... activity represents error signals (difference between expected and actual sensory inputs, e.g., the template and the actual drawing). • Experimentally, simultaneous activation of climbing fibers and parallel fibers converging onto the same Purkinje cell can cause longterm depression of parallel fibe ...
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Long-term depression

Long-term depression (LTD), in neurophysiology, is an activity-dependent reduction in the efficacy of neuronal synapses lasting hours or longer following a long patterned stimulus. LTD occurs in many areas of the CNS with varying mechanisms depending upon brain region and developmental progress. LTD in the hippocampus and cerebellum have been the best characterized, but there are other brain areas in which mechanisms of LTD are understood. LTD has also been found to occur in different types of neurons that release various neurotransmitters, however, the most common neurotransmitter involved in LTD is L-glutamate. L-glutamate acts on the N-methyl-D- asparate receptors (NMDARs), α-amino-3-hydroxy-5-methylisoxazole-4-propionicacid receptors (AMPARs), kainate receptors (KARs) and metabotropic glutamate receptors (mGluRs) during LTD. It can result from strong synaptic stimulation (as occurs in the cerebellar Purkinje cells) or from persistent weak synaptic stimulation (as in the hippocampus). Long-term potentiation (LTP) is the opposing process to LTD; it is the long-lasting increase of synaptic strength. In conjunction, LTD and LTP are factors affecting neuronal synaptic plasticity. LTD is thought to result mainly from a decrease in postsynaptic receptor density, although a decrease in presynaptic neurotransmitter release may also play a role. Cerebellar LTD has been hypothesized to be important for motor learning. However, it is likely that other plasticity mechanisms play a role as well. Hippocampal LTD may be important for the clearing of old memory traces. Hippocampal/cortical LTD can be dependent on NMDA receptors, metabotropic glutamate receptors (mGluR), or endocannabinoids. The result of the underlying-LTD molecular mechanism is the phosphorylation of AMPA glutamate receptors and their elimination from the surface of the parallel fiber-Purkinje cell (PF-PC) synapse.LTD is one of several processes that serves to selectively weaken specific synapses in order to make constructive use of synaptic strengthening caused by LTP. This is necessary because, if allowed to continue increasing in strength, synapses would ultimately reach a ceiling level of efficiency, which would inhibit the encoding of new information.
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